diff --git a/packages/schematics/angular/refactor/jasmine-vitest/index.ts b/packages/schematics/angular/refactor/jasmine-vitest/index.ts
index a7e34ad26c02..2498855c4607 100644
--- a/packages/schematics/angular/refactor/jasmine-vitest/index.ts
+++ b/packages/schematics/angular/refactor/jasmine-vitest/index.ts
@@ -121,6 +121,7 @@ export default function (options: Schema): Rule {
       const content = tree.readText(file);
       const newContent = transformJasmineToVitest(file, content, reporter, {
         addImports: !!options.addImports,
+        browserMode: !!options.browerMode,
       });
 
       if (content !== newContent) {
diff --git a/packages/schematics/angular/refactor/jasmine-vitest/schema.json b/packages/schematics/angular/refactor/jasmine-vitest/schema.json
index 99f34057ffb5..cb361280e473 100644
--- a/packages/schematics/angular/refactor/jasmine-vitest/schema.json
+++ b/packages/schematics/angular/refactor/jasmine-vitest/schema.json
@@ -30,6 +30,11 @@
       "type": "boolean",
       "description": "Whether to add imports for the Vitest API. The Angular `unit-test` system automatically uses the Vitest globals option, which means explicit imports for global APIs like `describe`, `it`, `expect`, and `vi` are often not strictly necessary unless Vitest has been configured not to use globals.",
       "default": false
+    },
+    "browserMode": {
+      "type": "boolean",
+      "description": "Whether the tests are intended to run in browser mode. If true, the `toHaveClass` assertions are left as is because Vitest browser mode has such an assertion. Otherwise they're migrated to an equivalent assertion.",
+      "default": false
     }
   }
 }
diff --git a/packages/schematics/angular/refactor/jasmine-vitest/test-file-transformer.integration_spec.ts b/packages/schematics/angular/refactor/jasmine-vitest/test-file-transformer.integration_spec.ts
index 8944e34dfa14..079718212d84 100644
--- a/packages/schematics/angular/refactor/jasmine-vitest/test-file-transformer.integration_spec.ts
+++ b/packages/schematics/angular/refactor/jasmine-vitest/test-file-transformer.integration_spec.ts
@@ -11,10 +11,17 @@ import { format } from 'prettier';
 import { transformJasmineToVitest } from './test-file-transformer';
 import { RefactorReporter } from './utils/refactor-reporter';
 
-async function expectTransformation(input: string, expected: string): Promise<void> {
+async function expectTransformation(
+  input: string,
+  expected: string,
+  options: { addImports: boolean; browserMode: boolean } = {
+    addImports: false,
+    browserMode: false,
+  },
+): Promise<void> {
   const logger = new logging.NullLogger();
   const reporter = new RefactorReporter(logger);
-  const transformed = transformJasmineToVitest('spec.ts', input, reporter, { addImports: false });
+  const transformed = transformJasmineToVitest('spec.ts', input, reporter, options);
   const formattedTransformed = await format(transformed, { parser: 'typescript' });
   const formattedExpected = await format(expected, { parser: 'typescript' });
 
@@ -389,6 +396,44 @@ describe('Jasmine to Vitest Transformer - Integration Tests', () => {
     await expectTransformation(jasmineCode, vitestCode);
   });
 
+  it('should not transform toHaveClass in browser mode', async () => {
+    const jasmineCode = `
+      describe('toHaveClass in browser mode', () => {
+        let el: HTMLElement;
+
+        beforeEach(() => {
+          el = document.createElement('div');
+        });
+
+        it('should handle DOM matchers like toHaveClass', () => {
+          el.classList.add('my-class');
+          expect(el).withContext('element should have my-class').toHaveClass('my-class');
+          el.classList.remove('my-class');
+          expect(el).not.toHaveClass('my-class');
+        });
+      });
+    `;
+
+    const vitestCode = `
+      describe('toHaveClass in browser mode', () => {
+        let el: HTMLElement;
+
+        beforeEach(() => {
+          el = document.createElement('div');
+        });
+
+        it('should handle DOM matchers like toHaveClass', () => {
+          el.classList.add('my-class');
+          expect(el, 'element should have my-class').toHaveClass('my-class');
+          el.classList.remove('my-class');
+          expect(el).not.toHaveClass('my-class');
+        });
+      });
+    `;
+
+    await expectTransformation(jasmineCode, vitestCode, { addImports: false, browserMode: true });
+  });
+
   it('should add TODOs for unsupported Jasmine features', async () => {
     const jasmineCode = `
       describe('Unsupported Features', () => {
diff --git a/packages/schematics/angular/refactor/jasmine-vitest/test-file-transformer.ts b/packages/schematics/angular/refactor/jasmine-vitest/test-file-transformer.ts
index eb8afdfe0449..cc9563bd3e15 100644
--- a/packages/schematics/angular/refactor/jasmine-vitest/test-file-transformer.ts
+++ b/packages/schematics/angular/refactor/jasmine-vitest/test-file-transformer.ts
@@ -152,7 +152,7 @@ export function transformJasmineToVitest(
   filePath: string,
   content: string,
   reporter: RefactorReporter,
-  options: { addImports: boolean },
+  options: { addImports: boolean; browserMode: boolean },
 ): string {
   const contentWithPlaceholders = preserveBlankLines(content);
 
@@ -189,7 +189,9 @@ export function transformJasmineToVitest(
         }
 
         for (const transformer of callExpressionTransformers) {
-          transformedNode = transformer(transformedNode, refactorCtx);
+          if (!(options.browserMode && transformer === transformToHaveClass)) {
+            transformedNode = transformer(transformedNode, refactorCtx);
+          }
         }
       } else if (ts.isPropertyAccessExpression(transformedNode)) {
         for (const transformer of propertyAccessExpressionTransformers) {
diff --git a/packages/schematics/angular/refactor/jasmine-vitest/test-helpers.ts b/packages/schematics/angular/refactor/jasmine-vitest/test-helpers.ts
index a93875b912e9..9aa6532206da 100644
--- a/packages/schematics/angular/refactor/jasmine-vitest/test-helpers.ts
+++ b/packages/schematics/angular/refactor/jasmine-vitest/test-helpers.ts
@@ -30,7 +30,10 @@ export async function expectTransformation(
 ): Promise<void> {
   const logger = new logging.NullLogger();
   const reporter = new RefactorReporter(logger);
-  const transformed = transformJasmineToVitest('spec.ts', input, reporter, { addImports });
+  const transformed = transformJasmineToVitest('spec.ts', input, reporter, {
+    addImports,
+    browserMode: false,
+  });
   const formattedTransformed = await format(transformed, { parser: 'typescript' });
   const formattedExpected = await format(expected, { parser: 'typescript' });