diff --git a/changelog.d/19060.bugfix b/changelog.d/19060.bugfix
new file mode 100644
index 00000000000..81a6e545670
--- /dev/null
+++ b/changelog.d/19060.bugfix
@@ -0,0 +1 @@
+Fix a bug introduced in 1.136.0 that would prevent Synapse from being able to be `reload`-ed more than once when running under systemd.
\ No newline at end of file
diff --git a/synapse/app/_base.py b/synapse/app/_base.py
index b416b66ac6e..e30151dfb48 100644
--- a/synapse/app/_base.py
+++ b/synapse/app/_base.py
@@ -591,9 +591,9 @@ async def _handle_sighup(*args: Any, **kwargs: Any) -> None:
                 # we're not using systemd.
                 sdnotify(b"RELOADING=1")
 
-            for sighup_callbacks in _instance_id_to_sighup_callbacks_map.values():
-                for func, args, kwargs in sighup_callbacks:
-                    func(*args, **kwargs)
+                for sighup_callbacks in _instance_id_to_sighup_callbacks_map.values():
+                    for func, args, kwargs in sighup_callbacks:
+                        func(*args, **kwargs)
 
                 sdnotify(b"READY=1")