diff --git a/llvm/lib/Transforms/IPO/OpenMPOpt.cpp b/llvm/lib/Transforms/IPO/OpenMPOpt.cpp
index 5e2247f2a88d0..d9c8412008a21 100644
--- a/llvm/lib/Transforms/IPO/OpenMPOpt.cpp
+++ b/llvm/lib/Transforms/IPO/OpenMPOpt.cpp
@@ -5020,6 +5020,29 @@ struct AAKernelInfoCallSite : AAKernelInfo {
       case OMPRTL___kmpc_free_shared:
         // Return without setting a fixpoint, to be resolved in updateImpl.
         return;
+      case OMPRTL___kmpc_distribute_static_loop_4:
+      case OMPRTL___kmpc_distribute_static_loop_4u:
+      case OMPRTL___kmpc_distribute_static_loop_8:
+      case OMPRTL___kmpc_distribute_static_loop_8u:
+      case OMPRTL___kmpc_distribute_for_static_loop_4:
+      case OMPRTL___kmpc_distribute_for_static_loop_4u:
+      case OMPRTL___kmpc_distribute_for_static_loop_8:
+      case OMPRTL___kmpc_distribute_for_static_loop_8u:
+      case OMPRTL___kmpc_for_static_loop_4:
+      case OMPRTL___kmpc_for_static_loop_4u:
+      case OMPRTL___kmpc_for_static_loop_8:
+      case OMPRTL___kmpc_for_static_loop_8u:
+        // Parallel regions might be reached by these calls, as they take a
+        // callback argument potentially containing arbitrary user-provided
+        // code.
+        ReachedUnknownParallelRegions.insert(&CB);
+        // TODO: The presence of these calls on their own does not prevent a
+        // kernel from being SPMD-izable. We mark it as such because we need
+        // further changes in order to also consider the contents of the
+        // callbacks passed to them.
+        SPMDCompatibilityTracker.indicatePessimisticFixpoint();
+        SPMDCompatibilityTracker.insert(&CB);
+        break;
       default:
         // Unknown OpenMP runtime calls cannot be executed in SPMD-mode,
         // generally. However, they do not hide parallel regions.
diff --git a/offload/test/offloading/fortran/target-generic-loops.f90 b/offload/test/offloading/fortran/target-generic-loops.f90
new file mode 100644
index 0000000000000..07bcbfd2c8752
--- /dev/null
+++ b/offload/test/offloading/fortran/target-generic-loops.f90
@@ -0,0 +1,130 @@
+! Offloading test for generic target regions containing different kinds of
+! loop constructs inside.
+! REQUIRES: flang, amdgpu
+
+! RUN: %libomptarget-compile-fortran-run-and-check-generic
+program main
+  integer :: i1, i2, n1, n2, counter
+
+  n1 = 100
+  n2 = 50
+
+  counter = 0
+  !$omp target map(tofrom:counter)
+    !$omp teams distribute reduction(+:counter)
+    do i1=1, n1
+      counter = counter + 1
+    end do
+  !$omp end target
+
+  ! CHECK: 1 100
+  print '(I2" "I0)', 1, counter
+
+  counter = 0
+  !$omp target map(tofrom:counter)
+    !$omp parallel do reduction(+:counter)
+    do i1=1, n1
+      counter = counter + 1
+    end do
+    !$omp parallel do reduction(+:counter)
+    do i1=1, n1
+      counter = counter + 1
+    end do
+  !$omp end target
+
+  ! CHECK: 2 200
+  print '(I2" "I0)', 2, counter
+
+  counter = 0
+  !$omp target map(tofrom:counter)
+    counter = counter + 1
+    !$omp parallel do reduction(+:counter)
+    do i1=1, n1
+      counter = counter + 1
+    end do
+    counter = counter + 1
+    !$omp parallel do reduction(+:counter)
+    do i1=1, n1
+      counter = counter + 1
+    end do
+    counter = counter + 1
+  !$omp end target
+
+  ! CHECK: 3 203
+  print '(I2" "I0)', 3, counter
+
+  counter = 0
+  !$omp target map(tofrom: counter)
+    counter = counter + 1
+    !$omp parallel do reduction(+:counter)
+    do i1=1, n1
+      counter = counter + 1
+    end do
+    counter = counter + 1
+  !$omp end target
+
+  ! CHECK: 4 102
+  print '(I2" "I0)', 4, counter
+
+
+  counter = 0
+  !$omp target teams distribute reduction(+:counter)
+  do i1=1, n1
+    !$omp parallel do reduction(+:counter)
+    do i2=1, n2
+      counter = counter + 1
+    end do
+  end do
+
+  ! CHECK: 5 5000
+  print '(I2" "I0)', 5, counter
+
+  counter = 0
+  !$omp target teams distribute reduction(+:counter)
+  do i1=1, n1
+    counter = counter + 1
+    !$omp parallel do reduction(+:counter)
+    do i2=1, n2
+      counter = counter + 1
+    end do
+    counter = counter + 1
+  end do
+
+  ! CHECK: 6 5200
+  print '(I2" "I0)', 6, counter
+
+  counter = 0
+  !$omp target teams distribute reduction(+:counter)
+  do i1=1, n1
+    !$omp parallel do reduction(+:counter)
+    do i2=1, n2
+      counter = counter + 1
+    end do
+    !$omp parallel do reduction(+:counter)
+    do i2=1, n2
+      counter = counter + 1
+    end do
+  end do
+
+  ! CHECK: 7 10000
+  print '(I2" "I0)', 7, counter
+
+  counter = 0
+  !$omp target teams distribute reduction(+:counter)
+  do i1=1, n1
+    counter = counter + 1
+    !$omp parallel do reduction(+:counter)
+    do i2=1, n2
+      counter = counter + 1
+    end do
+    counter = counter + 1
+    !$omp parallel do reduction(+:counter)
+    do i2=1, n2
+      counter = counter + 1
+    end do
+    counter = counter + 1
+  end do
+
+  ! CHECK: 8 10300
+  print '(I2" "I0)', 8, counter
+end program
diff --git a/offload/test/offloading/fortran/target-spmd-loops.f90 b/offload/test/offloading/fortran/target-spmd-loops.f90
new file mode 100644
index 0000000000000..7407f0c0768cb
--- /dev/null
+++ b/offload/test/offloading/fortran/target-spmd-loops.f90
@@ -0,0 +1,39 @@
+! Offloading test for generic target regions containing different kinds of
+! loop constructs inside.
+! REQUIRES: flang, amdgpu
+
+! RUN: %libomptarget-compile-fortran-run-and-check-generic
+program main
+  integer :: i1, n1, counter
+
+  n1 = 100
+
+  counter = 0
+  !$omp target parallel do reduction(+:counter)
+  do i1=1, n1
+    counter = counter + 1
+  end do
+
+  ! CHECK: 1 100
+  print '(I2" "I0)', 1, counter
+
+  counter = 0
+  !$omp target map(tofrom:counter)
+    !$omp parallel do reduction(+:counter)
+    do i1=1, n1
+      counter = counter + 1
+    end do
+  !$omp end target
+
+  ! CHECK: 2 100
+  print '(I2" "I0)', 2, counter
+
+  counter = 0
+  !$omp target teams distribute parallel do reduction(+:counter)
+  do i1=1, n1
+    counter = counter + 1
+  end do
+
+  ! CHECK: 3 100
+  print '(I2" "I0)', 3, counter
+end program