My profile-cond causes the shortcut keys to stop working, but they work normally when used with mpv.exe.

[dunkeng]

[vulkan]
profile-cond=((video_codec ~= h264) or (video_codec ~= hevc))
hwdec=vulkan
gpu-api=vulkan
gpu-context=winvk
hwdec-codecs=h264,hevc
profile-restore=copy

[d3d11]
profile-cond=((video_codec ~= mjpeg) or (video_codec ~= mpeg2video) or (video_codec ~= mpeg4) or (video_codec ~= vc1) or (video_codec ~= vp9))
hwdec=d3d11va
gpu-api=d3d11
gpu-context=d3d11
d3d11va-zero-copy=yes
hwdec-codecs=mjpeg,mpeg2video,mpeg4,vc1,vp9
profile-restore=copy

As long as you don't use profile-cond, it will work properly.

[dunkeng]

hwdec=vulkan,d3d11va
gpu-api=vulkan,d3d11
gpu-context=winvk,d3d11
I solved my need by using a simpler method.