SAFES_200925_2.csv

PDB_ID,variant,mean_ddG_xtal,std_ddG_xtal,mean_ddG_infc_xtal,std_ddG_infc_xtal,mean_ddG_af2,std_ddG_af2,mean_ddG_infc_af2,std_ddG_infc_af2,mean_ddG_af3,std_ddG_af3,mean_ddG_infc_af3,std_ddG_infc_af3
1MHP,F283=,1.0453906259163166e-13,0.076698799035922,,,-5.226982041639516e-14,0.0016255328302754,-0.0052127811951955,0.0004083437028962,-5.227068777813315e-14,0.0324080862344015,0.0089680370458426,0.0037015300647684
1MHP,F283W,0.9760919540230626,0.0030367459341537,0.0625964351688342,0.0064060804774037,1.1059770114942349,0.0,-0.033536885248931,7.392191557040548e-14,2.0777011494252373,0.0126259018192319,0.947402122700592,0.0586459819143822
1MHP,F283Y,0.353218390804739,0.2231943001074888,-0.1317921731510298,0.3886539673369522,0.2586206896551724,0.0028896103655142,-0.0001845296236589,0.0004085367629325,0.611724137931048,0.0026008525285146,0.4295765683437644,0.0091955145427742
1MHP,G237=,0.0,0.0,,,0.0,0.0,0.0007179772287939,3.6960344467836076e-14,0.0,0.0,0.0209753652771546,6.283258150653994e-12
1MHP,G237A,0.2982758620688903,0.0,-0.2377877697006561,0.0068250923058619,-0.3920689655173003,0.0009753196981652,0.3843702824247106,0.0023030853343765,-1.2413793103447963,0.0,-0.6139283584465813,0.0
1MHP,G237N,1.6044827586206185,2.220446049250313e-16,0.21836329083956,0.0068250923053445,2.397816091954009,0.0006502131321103,1.9996441105664893,0.0033803917487461,2.191379310344834,0.0,1.5963712400240893,6.135397966169067e-12
1MHP,G237Q,0.9299999999998834,0.0,1.0353135275243237,0.0023821431096106,2.2563218390804725,0.0001625532829907,2.6149522017976388,0.0027656546179589,1.0568965517241569,0.0,0.1811262717365025,5.9875737594053685e-12
1MHP,G237S,1.2937931034482597,0.0,0.846243316558235,0.0082773740204258,0.7049425287356105,0.1284220318274289,1.2332585333055297,0.0153924231581391,0.4841379310344815,0.0,0.7515595145459569,1.1102230246251563e-16
1MHP,G237W,3.4289655172413656,0.0,1.7303472733702023,0.006825092305862,8.863103448275853,0.0017126051064199,8.354283256309524,0.0023555567030779,5.2800000000000695,0.0262567583735521,3.1024336418309844,0.0010453934543446
1MHP,G238=,0.0,0.0,,,-1.045413755562663e-13,0.167951527776307,0.0014128466596335,0.0011022269013322,0.0,0.0,-0.0035026199730995,0.0
1MHP,G238I,-0.4937931034483077,0.1104557632006916,-1.3235059203096735,0.0821805053887774,-0.5454022988507189,0.1683268090704943,-0.5225830833686181,0.0038050704839781,-0.5778160919540803,0.0009887730192133,-1.6608978753772563,0.0146236580684348
1MHP,G238M,-1.4082758620690647,0.0,-1.4527830369124055,0.0068250923057881,-1.635632183908153,0.1706811794018072,-1.447099457164342,0.0013770127342937,-1.3647126436781665,0.0022757459624596,-1.6412247659103345,0.0049741858947683
1MHP,G238N,-2.088965517241377,0.0,-1.2684573840941336,0.0,-1.2888505747127703,0.1663804915289718,-0.3238411171891857,0.0041368860970066,-1.3731034482758522,0.0,-0.8131513867655139,1.1102230246251563e-16
1MHP,G238T,-1.263448275862143,0.0,-0.5898001115535627,0.0,-1.240000000000158,0.1675924348053551,-0.411005115681694,0.0048632893936018,-0.9168965517241744,0.0,-0.5072809890884594,1.477980414106139e-13
1MHP,G238Y,-1.5694252873563217,0.0042263853587901,-1.0379137746291425,0.0128730168379421,-2.619885057471383,0.0005860941969611,-1.5022647724691425,0.0020661506946866,-1.3793103448275863,0.0,-1.1933458440470814,0.0
1MHP,G284=,0.0,0.0,,,3.614007241618348e-20,0.0012695817261165,-0.0053006997337439,0.0007274918653389,1.0453790610931437e-13,0.0322671337708495,-0.0330790575440684,0.0029457408303329
1MHP,G284F,0.4152873563218194,0.0134035014543093,-1.994576416931439,0.0030067463874686,-0.6940229885056962,0.0019506393963305,-1.1747671465923697,0.0057120361596097,-0.0133333333332271,0.4054584300669892,-2.642192834473516,0.3900498196458659
1MHP,G284I,0.6312643678160093,0.0812766415156951,-1.3817504956230695,0.0334990621937807,-0.7789655172413843,0.0001625532830645,-1.298670620181608,0.0072417228515302,-0.3095402298849249,0.0301197679735234,-1.839402844802862,0.0037419786498343
1MHP,G284L,0.7857471264367568,0.0816837930063129,-1.7450777291415065,0.0468287691475248,-0.1328735632183849,0.0044189385716933,-1.1065321551710368,0.0020012386633001,-0.9158620689653428,0.7909058174997012,-1.9005039434676647,0.2394247835287266
1MHP,G284M,2.7999999999999106,0.3020344545445989,-1.1787446386182867,0.0639749256865571,0.3144827586207277,0.4200380607986931,-1.022045021998254,0.0120985134872073,0.7309195402299808,0.5127748144216998,-0.8376824111357942,0.2683890724700477
1MHP,G284S,0.5185057471263285,0.0766760579472602,0.0248408707207561,0.0374754821260744,0.4467816091954742,0.0038432766660505,-0.1269611459813456,0.0015567920993437,0.5457471264368916,0.0275531411026628,0.0257491812120254,0.0030784085948008
1MHP,G284V,0.2826436781609003,0.0783633281809709,-1.168836858622247,0.0281281404010096,-0.560574712643725,0.0,-1.4336304359440044,1.89640127892752e-06,0.1619540229886224,0.002685821021935,-1.3239840604259288,0.0034870415940734
1MHP,G286=,-5.227068777813315e-14,0.0409634273239026,,,0.0,0.0,0.0056487315500111,0.0,0.0,0.0329742850521553,-0.0587276089739437,0.0027477790101587
1MHP,G286S,3.750114942528655,0.0191812873976939,-0.1502175947532133,0.0116597932881577,3.871379310344728,0.3243379182519755,-0.3010270159264674,0.405928693040969,3.845517241379273,0.0040246302068668,-0.4001309034202185,0.0025922077053993
1MHP,G494=,-1.0453964083279033e-13,0.0026858210219954,,,1.5680943134016005e-13,0.0,0.042267166480887,0.0,0.0,0.1601271129369917,0.0406692176730579,0.0557422287717044
1MHP,G494Q,2.8017241379309823,2.154132659532192,0.0848648627304843,0.1271128249117802,-1.1762068965515875,0.0,-0.7613068631759501,0.0,0.9871264367816314,1.5991172835878198,0.2999062320105131,0.2015610114608717
1MHP,G494S,0.0932183908045103,0.000325106566055,0.2655445843962904,0.0017461751044512,-0.62379310344803,0.0,0.0310857044785436,0.0,-0.1780459770114917,0.1596295586149881,0.408068024044146,0.0556327471943257
1MHP,H240=,0.0,0.0,,,1.5680946124918556e-13,0.0008127664151007,0.0127667428256668,0.0010597441439699,0.0,0.0,0.0188821320541043,0.0
1MHP,H240Y,-0.0631034482758595,0.0,0.2478155328149689,0.0083142179325663,-0.6679310344825667,0.0056893649061489,-1.0375258735789352,0.0058660787420646,0.3396551724136802,0.0,0.5899023751304601,0.0
1MHP,H433=,1.0453906259163166e-13,0.0404261223723601,,,-5.226978427632276e-14,0.0006502131321101,-0.019980083879582,0.0005470387727932,-1.5680975036976485e-13,0.1108627691056839,0.3909449754049395,0.0454901830598493
1MHP,H433K,1.410000000000189,0.0222697997753282,0.3543511296673638,0.0051318957979179,1.9278160919539635,0.0110536232461688,0.3538917667812329,0.0069279170613205,0.5027586206895273,0.0342767794383864,0.2801943627169728,0.0249997366744832
1MHP,H433R,0.5702298850575511,0.0465972531719503,0.0100664696848938,0.0068998926386345,1.3316091954021985,0.0055554234361209,0.348130909640194,0.0022639529729201,-0.789080459770299,0.1753264324260828,-0.3871185909987428,0.0423503206207365
1MHP,H433W,-0.2109195402297847,0.017776373970205,-0.6583275706083671,0.0160661660981353,1.1109195402297765,0.0001625532830645,0.2168440019035391,0.0014324166998992,-1.1166666666668403,0.1660616048316941,-0.2464260363232782,0.0538940453128669
1MHP,K248=,0.0,0.0,,,-5.226982041639516e-14,0.0004876598491195,0.0025030078607796,0.0013017918941714,1.5680943134016005e-13,0.0,-0.0057678102247932,8.673617379884035e-19
1MHP,K248D,0.4300000000001029,5.551115123125783e-17,-0.0848246853845545,0.0,1.066206896551758,0.0,-0.0009729846209634,0.0,0.2317241379312,0.0,-0.011439890243874,1.3305724008420986e-12
1MHP,K248E,0.7100000000000678,0.0,-0.0813743470024715,0.0023821411503062,1.2520689655171926,0.0,0.0023788187980051,1.772270688048565e-06,0.3948275862070471,0.0,-0.0031290424214665,4.336808689942021e-19
1MHP,K248N,0.4510344827586182,0.0,-0.0869669187384444,0.0214859281215222,1.3517241379310596,0.0,0.0069591561748961,5.507090303511971e-12,0.3544827586209317,0.0,-0.017868197139627,0.0
1MHP,K248Q,0.7389655172413893,1.1102230246251563e-16,-0.0905553751293667,0.0023821411502323,0.8996551724137668,0.0,0.0048914064741281,0.0,0.5465517241381004,0.0,-0.0139427238859909,0.0
1MHP,L244=,-5.226982041639516e-14,0.0024274381703155,,,-5.226982041639516e-14,0.0017880861133399,0.0075187047869234,0.0001204738957316,1.5680943134016005e-13,0.0,0.0012767668379732,0.0
1MHP,L244D,1.531264367816001,0.0,0.0142689812185056,0.0068250923059359,1.8671264367815728,0.0048028925094291,0.0027596887069444,0.0007567504067859,1.494827586207066,0.0,0.0472389684107671,7.392191557040548e-14
1MHP,L451=,5.226953129581583e-14,0.0080771154440422,,,0.0,0.0,-0.0250261037428739,1.6517892096686285e-06,5.226982041639516e-14,0.0016255328302754,0.0263014942688589,0.0009403358561121
1MHP,L451F,2.2071264367816874,0.0152384491210425,0.2752902323375346,0.1590991881156641,-0.187356321839093,0.2914580364753022,-0.2993782128384146,0.0046409070726202,3.0788505747126504,0.0009753196981652,-0.4349824756399744,0.0048276120133075
1MHP,L451K,2.690114942528788,0.1719055343768013,0.8847453533726052,0.0995484770442792,1.0110344827587048,0.0,0.4626206920332036,5.580998317252732e-12,3.6310344827586896,0.0016497356430327,1.8014255351289616,0.003885207274913
1MHP,L451W,1.6495402298851227,0.1450819696237331,0.0925246685217163,0.0290067935921759,-0.6585057471264154,0.0033589975163246,-0.0655196700339881,0.0017756384076519,3.0548275862069225,0.0036745672099395,-0.8450909776740508,0.0028819627083125
1MHP,L451Y,2.571609195402357,0.2490938525750749,0.4137377397982445,0.1020519769807183,-0.7032183908045383,0.0008127664151007,-0.1048472502221666,0.0039697061161558,2.273678160919587,0.3625974249607317,0.2644365690420973,0.0829306987647958
1MHP,N432=,5.226978427632276e-14,0.0004876598490456,,,1.5680943134016005e-13,0.0,0.0466929276999821,1.1088123786675448e-13,0.0,0.0022757459624437,0.0032528680809452,0.0037667017828664
1MHP,N432K,1.325862068965553,0.0307548062167303,0.9504338887205742,0.0155958871660895,2.530000000000153,0.0,2.571280257183005,3.291936836966915e-06,1.2109195402298685,0.1390649749145721,2.5207825409509903,0.0470393721018202
1MHP,N432V,-1.329540229885006,0.0114030867358808,-1.2787738371423922,0.0258400616076682,-0.4917241379308538,0.0,-0.1704409854104774,3.6962594456065816e-14,-0.6649425287356677,0.0154451283055131,0.0001079617145635,0.0030926834119183
1MHP,N432W,0.4519540229885337,0.1096043160219214,-0.2862532683086059,0.1215917078465246,2.409540229885289,0.012028942944334,1.3515784741126933,0.003598749715165,-0.233793103448288,0.8907919910120217,-0.1097569484888492,1.1613060604076333
1MHP,N432Y,-0.3528735632183051,0.055768570351331,-0.952947384704652,0.1428255768433555,1.92919540229902,0.0320229967572028,1.3662526058936069,0.071958797004893,-0.5440229885057672,0.0012272503737529,0.5516151637776006,0.0022976985845547
1MHP,N454=,1.0453906259163166e-13,0.0115412830952884,,,-1.5680943134016005e-13,0.0,-0.0025980781890666,0.0,1.5680935282896834e-13,0.0021503778084678,0.0119149754942324,0.0008022856738878
1MHP,N454D,-0.4521839080458951,0.0079101841536098,-1.1806380308390263,0.0251331316459187,0.5025287356320615,0.0094280904158194,-0.0001261342839663,0.0020799215656101,0.5274712643679139,0.0035278182191452,-0.6712635170026845,0.0024144110979552
1MHP,N454E,0.3693103448277129,0.0076400043024794,0.054786776928142,0.010110049440263,0.0679310344824851,0.0,0.008589659177959,3.696095778520274e-14,0.3706896551725602,0.0006502131321101,-0.0520120022746982,0.0094817590141948
1MHP,N454K,-0.0078160919538904,0.0073148977363504,-0.0091568895364073,0.0012676443883049,0.0682758620687623,0.0,-0.0023685114848015,1.772270651088425e-06,-0.1864367816090729,0.0019164749426418,-0.2924422262134842,0.0019816174020818
1MHP,N454R,-0.7506896551723035,0.0033353145123244,-0.5361339157427168,0.0211065572419289,-0.1437931034484038,0.0,0.0021265060727587,0.0,-0.0185057471262866,0.0026759647648201,0.1549802970272537,0.001237989801937
1MHP,N454Y,-1.418735632183786,0.0049278048529052,-1.0146036611215994,0.0030058831608987,-0.7341379310346069,1.1102230246251563e-16,-0.0201783156706698,0.0,-1.914597701149286,0.0056239677346135,-1.4186783925600237,0.0062813174214467
1MHP,N495=,1.5680943134016005e-13,0.0,,,1.0453962276275413e-13,0.0004300755617159,0.0458200622098314,0.0020183673941021,0.0,0.0,-0.0005706388133305,0.0
1MHP,N495D,1.648965517241589,0.0,0.7123289834112518,0.0068243704324769,0.8478160919540988,1.1102230246251563e-16,-0.032744463048831,4.978063660118369e-07,2.083448275862197,0.0,1.770761969169614,0.0
1MHP,R215=,0.0,0.0317553569528451,,,-1.0453962276275413e-13,0.000325106566055,-0.0015883655343018,0.0006600015507536,1.0453674962699705e-13,0.0574537904470059,-0.0047352846570578,0.0093541978269773
1MHP,R215Q,0.16471264367816,0.0027345694835038,0.3011934939432053,0.0048573994861792,-0.1287356321841045,0.0,-0.1066426523966557,7.392518674109674e-14,-0.2228735632183214,0.0317890390600742,0.0998122740008313,0.0156775686399647
1MHP,S219=,-1.0453906259163166e-13,0.0204991226864885,,,-5.2273000742767785e-14,0.0911923917806341,-0.0070334379576586,0.0008923588591395,0.0,0.0,0.003333540675283,0.0
1MHP,S219A,-0.9637931034484056,0.0024545007476088,0.0122508160826725,0.0062039399036907,-1.650344827586279,0.002966319057628,0.0002708579401231,0.0011062221524833,-1.1671264367816612,0.0076607276795211,0.0018666841551435,0.0039520519616662
1MHP,S219Q,0.517701149425172,0.0110858478815401,-0.0237091580254792,0.0125204057051883,1.3802298850574497,0.0023443767878032,-0.1426669666290669,0.0017827454536524,-0.0919540229885266,0.0154425618879495,-0.0668708472380524,0.0008183648271995
1MHP,S219V,-0.2348275862069626,0.3706214853116023,-0.0239962555673858,0.0200094167345969,-0.0806896551723874,0.0,0.0493871477673716,7.391864458063701e-14,-0.885287356321865,0.0028481636076931,-0.0332845059615308,0.0065341234084835
1MHP,S236=,0.0,0.0,,,5.2269811381377074e-14,0.0001625532829905,-0.0033336087608012,0.0004139507709952,0.0,0.0,0.0410960221293423,0.0
1MHP,S236M,4.146781609195323,0.0007085533336914,1.8652817779882065,0.0128128885907759,3.4821839080461423,0.0,0.4769499870906855,3.6975719071099874e-14,4.588965517241324,0.3325840170822693,1.613367658914724,1.4214769546667032
1MHP,S236T,1.2210344827585216,0.0,0.8139381408646246,0.0068250922847945,1.1160919540230452,0.000325106566055,0.9106327678725116,0.0049114871314957,0.9144827586207048,1.1102230246251563e-16,1.0817690588333038,0.0
1MHP,S426=,0.0,0.0005631010902816,,,0.0,0.0009753196981652,-3.346634358244589e-06,9.399723443929518e-08,0.0,0.0,2.8624904659628903e-06,0.0
1MHP,S426R,-1.1179310344827194,0.0014898254479471,-0.0087746869093248,0.023390947364174,-1.3957471264368373,0.0011378729812298,-2.707125028645424e-05,4.014947306845961e-07,-1.5844827586207777,0.0,8.496183736810806e-05,0.0
1MHP,S430=,0.0,0.0,,,1.5680943134016005e-13,0.0,0.0567841707484358,5.617970723598581e-12,0.0,0.0,0.0092714139562868,0.0
1MHP,S430Q,-0.0580459770115068,0.0226124412585209,-0.1521731149663035,0.0323929380407937,0.1848275862070734,0.0,0.0452181172374037,0.0,0.2124137931034432,2.775557561562892e-17,-0.072238629453405,0.0
1MHP,S493=,5.226953129581583e-14,0.0554454451156065,,,-1.5680943134016005e-13,0.0,0.0070963183317359,5.562530513555064e-12,-1.0453964083279033e-13,0.0017880861134138,-0.0735974226712976,0.007031614692066
1MHP,S493K,0.1367816091954608,0.0340493839828651,-0.4352288746745791,0.0255931371707758,-0.1666666666668548,0.219772038658491,-0.814518385544742,0.2055924901874789,-0.0004597701150884,0.1256008941906584,-0.0691998154415442,0.1116257697249876
1MHP,S493Q,-0.0450574712642954,0.0193233399076272,-0.4472212575018048,0.0198248252711456,-2.200344827586472,0.0,-1.9268411234858032,0.0,-0.6371264367817276,0.2297711786903504,-0.5320040500629702,0.0104045258493444
1MHP,S493R,-0.5881609195400949,0.006014471472152,-0.3800884885819461,0.0087025643563072,-1.3686206896553468,0.0,-0.8726892261815605,1.1102230246251563e-16,-1.08620689655186,0.1290270715888822,-1.143960701923182,0.1865586159672306
1MHP,S493T,-0.1563218390803698,0.0110715374007183,-0.7179224262000421,0.0122851946572562,-0.8258620689656678,0.0,-0.4115664568614804,0.0,-0.7383908045978033,0.2872316511165121,-0.8059432490766074,0.0118545584309169
1MHP,S493W,0.0677011494253329,0.0779251006455322,-0.2385955104573859,0.018371121580244,-1.5800000000001155,0.0,-2.1762505829052765,3.705418202493709e-14,-0.5304597701151266,0.0,-1.2942162882080963,6.209296983213144e-12
1MHP,T217=,0.0,0.0,,,-1.5680938896904065e-13,0.0011378729812297,-0.007318834871397,0.0010075655418099,1.0453964083279033e-13,0.0041792319454467,0.001903834704117,0.0071595744519804
1MHP,T217N,1.7337931034483611,0.0,0.8508498734386979,1.1102230246251563e-16,0.672873563218265,0.0009753196981652,0.098470101341109,1.983525539131673e-05,1.2597701149426377,0.032067523553442,0.2975543023306785,0.0123374719240858
1MHP,T217Q,2.2531034482758985,0.0,0.9496420512279404,0.0068250928294421,2.855172413793016,0.0038018012433493,1.0566155990458246,0.0068733883691346,1.6368965517241885,0.0300723573607983,-0.4766764136751715,0.0042440290970637
1MHP,T217V,-0.3037931034482269,0.0062132789663615,-0.3878849898034588,0.0070994700946862,-0.2433333333334073,0.0029259590945697,0.3993110936905537,0.0006699589691723,-1.9642528735631075,0.0271707216930817,-1.196734373270792,0.0005818693392172
1MHP,T234=,0.0,0.0,,,0.0,0.0,-0.002880442724583,5.229887822222772e-12,-5.2270109536974495e-14,0.0215755423940059,0.052930836207807,0.0160847902154114
1MHP,T234E,2.191724137931111,0.0,0.0238430599764974,0.0068250937462802,2.3368965517241533,0.0009753196981652,-0.4273598874820714,0.0005814186696642,3.24471264367814,0.016249637942236,0.1291483993932108,0.015947336176333
1MHP,T234Q,1.6110344827586296,0.1945762797885191,0.3334542216187443,0.184679916190328,1.537816091954012,0.0032994712860654,-0.335225010163457,0.0019369479430841,1.4388505747125946,0.0331046455721916,-0.2763395924210627,0.0019318974997954
1MHP,T234V,-1.5231034482758332,0.0,-0.5101442573239224,7.389902765507827e-14,-0.5067816091954144,0.1178676085854364,-0.4043666800235827,0.0652537903106701,-0.6445977011494977,0.0,-0.0558362520570003,0.0
1MHP,W492=,0.0,0.0646169235522534,,,5.226978427632276e-14,0.0013888558590529,0.1547343912837711,0.0020905232104297,-1.5680975036976485e-13,0.0318442669745623,-0.0860866656170526,0.0107762005475275
1MHP,W492Q,3.0543678160918866,0.0115034446006611,1.084057046115185,0.0120209992495542,4.480804597701222,0.0001625532830644,2.2841622588126698,0.7347776715924487,2.8326436781607893,0.0283742797085114,0.494335165392673,0.010255815494036
1MHP,Y242=,0.0,0.0,,,0.0,0.0013004262642942,0.0388316723736786,0.0053227849411942,-5.227068777813315e-14,0.0557529325095897,0.0378410028635448,0.027737005844258
1MHP,Y242E,2.852758620689704,4.440892098500626e-16,1.5598036342457977,0.0,3.011954022988474,0.0602274720934553,1.5838672453867406,0.2573375325529624,3.5685057471263115,4.440892098500626e-16,2.0721478172214938,0.0
1MHP,Y242Q,0.7441379310344489,0.0,-0.3423445127083173,0.0082220740774866,1.972413793103484,0.0080344745367059,0.882284435827494,0.0066105441983806,1.6221839080459572,0.1400453845618786,0.4704982151263292,0.1726161340345843
1MHP,Y242W,0.0003448275862771,5.421010862427522e-20,0.2110630844587005,0.0023958175154366,1.191149425287337,0.1852299474680425,1.8566952677344264,0.0496560123708054,2.437586206896434,1.2731999046078348,2.11899483033088,1.033059289887013
1MHP,Y243=,-1.5680943134016005e-13,0.0,,,5.226982041639516e-14,0.0017582825908627,-0.0050798993421246,0.003012046654422,-2.0907928166558065e-13,0.0046462949267462,0.0010967783265218,0.000932376984104
1MHP,Y243E,4.274367816091786,0.1542630655968006,-0.0403562753135493,0.0016266896838839,4.064942528735712,0.01137872981215,0.0647404779564353,0.0013141129592661,4.448275862068683,0.0256587152005269,0.0155475942547232,0.0028881608534899
5E9D,A582=,-1.5680943134016005e-13,0.0,,,,,,,,,,
5E9D,A582Y,-1.93344827586232,0.0463276856639225,-0.1664581692055163,0.1172135612336175,,,,,,,,
5E9D,G401=,-5.226982041639516e-14,0.0035203201910285,,,1.0454253203858365e-13,0.0464438938447891,-0.2844861656393766,0.0096440643336605,1.0842021724855044e-19,0.0018746559115741,-0.0170942062459289,0.003292735637564
5E9D,G401E,-0.2537931034483378,0.0061190030594214,0.0317996811720839,0.0029312803064369,-0.2150574712642741,0.0025391634522331,-0.5176980311579227,0.0202208936879769,2.435632183908053,0.0019708538160225,0.8565323954294347,0.0092202639681676
5E9D,K470=,1.5680943134016005e-13,0.0,,,,,,,,,,
5E9D,K470Q,-1.4964367816091175,0.0065567635388565,-0.1949976276808166,0.0009923864968809,,,,,,,,
5E9D,N511=,2.0907812518326333e-13,0.0853479042752199,,,1.5680943134016005e-13,0.0,-0.0041772731077571,0.0,1.5680943134016005e-13,0.0,-0.0176365611853715,0.028300711130965
5E9D,N511G,0.498045977011713,0.1456610754347701,0.0014987196765032,0.0004703016756521,0.5772413793104941,0.0,-0.0132160045346339,7.66927198817597e-13,0.5641379310346283,0.0,0.1192043458883128,0.0281263892185189
5E9D,S424=,1.0453962276275413e-13,0.000325106566055,,,2.312964634635743e-18,0.0592637703615691,-0.699084141220612,0.0202668135602293,0.0,0.0009753196981652,-0.1102568977941031,0.047943294127518
5E9D,S424G,1.1559770114943857,0.0,0.2473273285980097,3.897313515279783e-05,-0.7451724137930712,0.0165285597803684,-0.7617786396660277,0.0080660899814432,1.0109195402299458,0.0095782375430277,0.1027812186242139,0.0382799201633665
5E9D,T464=,0.0,0.1862860623540033,,,,,,,,,,
5E9D,T464Q,-0.6278160919540218,0.0037387255096705,-0.2218002350258464,0.0001578723560739,,,,,,,,
5E9D,V533=,0.0,0.1543444064378044,,,-5.2273000742767785e-14,0.1893163814822558,-0.2560734631010066,0.2009723207642202,1.0453674962699705e-13,0.1616276701723829,0.1095263846761669,0.1402903326013901
5E9D,V533D,0.4164367816092008,0.0045514919249191,-0.1895138438005923,3.55836978326854e-05,2.898850574712569,0.0028481636076593,1.3436654911287989,0.0034840721837491,1.9429885057472307,0.07640056181007,0.4863680142527259,0.0182115914233338
5E9D,Y423=,5.2269964976684826e-14,0.0046091810702518,,,1.0453964083279033e-13,0.0072823145110034,-0.4687340461029946,0.0068720388080238,1.5681003949034416e-13,0.0162845616077728,0.0329558286893157,0.0743967342873848
5E9D,Y423W,0.3785057471265029,0.0470992352109644,-1.054196606656012,0.0053817056797643,1.6562068965517884,0.8441484016328663,-0.3876451449705841,0.6386692749726287,0.7132183908047985,0.0479937019693191,-0.7165798056198635,0.0423342287166921
1R0R,A284=,2.613489213816137e-14,0.000325106566055,,,0.0,0.0,-0.2689072891424248,0.0,2.6134765647907922e-14,0.0016971060988709,0.0241577620588147,0.0016584579369574
1R0R,A284C,0.5911494252873858,0.0014898254479109,-0.2947989770318234,0.0015825446866132,2.206781609195384,0.0020753413890984,0.5738920093261933,0.0014879520534199,1.3580459770115263,0.007660727679542,0.5376279708070797,0.0028592987031257
1R0R,A284D,2.117011494252861,0.0,2.1358216530120444,0.0,3.184597701149414,0.0047973877596868,3.223069811829061,0.0033835713431805,3.836666666666708,0.0896615087651727,3.662905560516385,0.0593530296446149
1R0R,A284E,4.30908045977012,0.140690500335509,3.353789965598606,0.0665365066097896,4.660459770114948,0.0008127664151747,3.544207650429128,0.0012790567208749,5.339540229885078,0.008668831096561,4.5551054700215365,0.0259134065695924
1R0R,A284F,1.467701149425314,0.0005631010903136,-0.4852859165328158,0.001336463566635,7.031954022988466,0.0064223977216968,4.0063092147842925,0.0025571395453158,5.477816091954067,3.119810316195037,2.85719995208324,2.4924031675577227
1R0R,A284G,2.580574712643681,0.0008601511233759,1.6708879496814426,0.0059222951919987,2.5186206896552026,0.0,1.5603466898011809,0.0,2.5663218390804854,0.0013305559658312,1.947262736713238,0.0124275112023905
1R0R,A284H,3.024942528735633,0.0373656929006505,2.118477569264772,0.0064837201624891,4.586666666666666,0.0019974881835485,3.216946023013307,0.0053272167019661,3.976666666666691,0.1956552115788222,2.812509904784961,0.4625941965226705
1R0R,A284I,0.7977011494252936,0.0168295646095428,0.0949597046588291,0.0137032960439808,1.0713793103448177,0.0,0.0377322141886891,0.0,1.2195402298851243,0.0046349069318761,1.183158760437703,0.0044942574179033
1R0R,A284K,4.7371264367816055,0.0747829907543688,4.178238811611387,0.0028028979777552,4.506666666666677,0.1002953756303988,2.957459820088584,0.0065735035762935,5.522413793103457,0.485845005397183,4.559296985887901,0.2734761709365258
1R0R,A284L,1.3116091954023057,0.6047814720053742,0.6558097787283311,0.5173835211443611,1.53505747126437,0.1449264395347216,0.0695444360445205,0.0763387321660188,2.639540229885103,0.3852744284995237,1.8167024528080824,0.7638005853242829
1R0R,A284M,2.12597701149429,0.2174962926959946,0.5409973920042057,0.1081444595659827,1.9226436781609035,0.0021131926793951,0.0565776131864252,0.0023966475996712,2.050804597701187,0.0093817328401629,0.6796327101882599,0.0044191481107211
1R0R,A284N,0.6409195402298876,0.0007085533336578,0.7358562977063637,0.0029436677889099,1.4154022988505577,0.0032510656606247,1.531737163830038,0.006876657483244,2.3781609195402624,0.1087481463479788,2.247088661621933,0.0171805476056187
1R0R,A284P,4.572413793103445,0.0032632343831182,2.6387898608095908,0.0036001210259742,5.200229885057441,0.0052848569804787,2.266890537017577,0.0116315143890649,5.35597701149425,0.0016255328303121,3.557616241580908,0.0096333643402969
1R0R,A284Q,2.7433333333333554,0.0178897254789199,1.8992564888552044,0.0168718967170735,2.292183908045978,0.0090637121855978,1.3515594541393738,0.0209125850720593,3.1724137931034897,0.1289075207147393,2.630223031417611,0.0136169219714525
1R0R,A284R,4.118965517241383,0.006794260554551,3.1670739028138204,0.0054267890770042,2.286666666666667,0.2239000210981319,0.785592113052333,0.1631544129575531,4.35954022988507,0.0760749364587026,3.511169060816768,0.0127863693109873
1R0R,A284S,1.5548275862069014,0.1142971537033822,1.770625372926787,0.3117140662767371,1.2517241379309938,0.0,1.6404220915956886,0.0,1.3783908045977231,0.0038432766660287,1.5662859310899897,0.0023659294171138
1R0R,A284T,0.9186206896551942,0.0008601511233759,0.6572893576202105,0.0019624139727967,2.072758620689644,0.4201218138658364,1.291292451671283,0.1375344809742145,1.7962068965517448,0.0024598775354981,1.343521992278422,0.002167347227442
1R0R,A284V,-0.5389655172413622,0.0037493118230393,-1.05526721703921,0.0016356484811318,0.6075862068965323,0.0,-0.1695351477118931,0.0,0.7150574712643945,0.0021989800540113,0.0253431451566374,0.0040881987211801
1R0R,A284W,6.609080459770119,0.0338528676310893,2.151386815908546,0.0432497955406391,10.121724137931032,0.1501409035656497,6.440303266488695,0.155151369395106,7.533448275862089,1.3244746438907222,3.83173183123081,0.5821922593956675
1R0R,A284Y,2.851379310344829,0.5825219088950505,0.9962423908589062,0.3769883985681831,8.110344827586202,0.1226484718277895,5.334336792528986,0.0269857895743591,5.092758620689684,0.7751205822515591,2.700522697671805,0.6560416006398628
1R0R,E288=,-5.2263748884229244e-14,0.1740179018069558,,,-5.2254497025690703e-14,0.267459433966244,-0.6050486850901623,0.0105528613173311,7.840473062459274e-14,0.0013305559658313,-0.0107907487137876,0.0023059675396073
1R0R,E288A,0.1837931034482419,0.0762250112829817,-0.2594694605144385,0.1041792707003149,0.5387356321838179,0.1123030270167831,-0.9466000690248694,0.0214159549202251,-0.0020689655171663,0.0004300755617159,-0.9994713218956108,0.0006985532031736
1R0R,E288C,0.5079310344827174,0.0698979117035081,-0.5620325614268824,0.1810814854309299,0.5848275862068143,0.1286616166537204,-0.9821912452339844,0.3888566136676954,0.0818390804598472,0.031861687480116,-0.9166982713875654,0.2084187683940837
1R0R,E288D,0.2751724137930518,0.0027634058115052,0.2212992142230355,0.0210716121642458,-0.0380459770115615,0.1376999021300736,-0.5317794452083625,0.0196142498905359,0.1256321839081068,0.188129776454994,-0.0134991230899017,0.1548107770258777
1R0R,E288F,-0.4914942528735971,0.665926680079844,-1.4170722353466365,0.1443300570310932,-1.0302298850575722,0.0144690685159099,-1.839647949366111,0.0689160205232607,-1.027241379310281,0.0004300755617228,-1.8310389129220603,0.0019340853728054
1R0R,E288G,1.4016091954022418,0.0794995244989463,0.2101439722409118,0.3966154127185042,1.1483908045976212,0.0119152776159909,-0.2233957958430212,0.0103494048358765,1.1158620689655792,0.0013888558590225,-0.308050250036046,0.0050318481086482
1R0R,E288H,0.768045977011444,0.4954061924800869,-0.4136202590725797,0.4327419251725956,0.0977011494251984,0.0095602891181224,-0.9007152674889349,0.0052951480800811,0.4766666666667114,0.0359242755499378,-0.2382241100972403,0.0146144447106649
1R0R,E288I,-1.1795402298851292,0.1211103777942246,-1.3391903612036862,0.3654690087068885,-0.7935632183908564,0.0121175813392673,-1.5999738955436615,0.0096263354523441,-0.5033333333332702,0.0627512521462597,-1.689780822825192,0.0356568397393036
1R0R,E288K,0.8374712643677705,0.1361063210807412,0.1741038649560971,0.0222415648995137,0.9748275862068176,0.0371970077655223,-0.1746113090406333,0.150019649471151,1.1109195402299592,0.0007449127239614,0.1866204564963931,0.002197212120078
1R0R,E288L,-1.25218390804603,0.1311533036589019,-1.2362293658534274,0.1298954873973952,-0.7700000000000863,0.0030885123775973,-1.8715321923241783,0.0170675463413727,-0.8322988505746588,0.0009050583763018,-1.2793260245354143,0.0035805920917146
1R0R,E288M,-0.611609195402315,0.0408008740408751,-1.0225437598246676,0.0804983868459291,-0.0350574712644535,0.0204526656915231,-1.5543306462355213,0.0465109789880583,-0.2643678160918965,0.0008127664151746,-1.5954399199646188,0.001112728064443
1R0R,E288N,0.5091954022988057,0.0014077527257361,-0.0409256767711772,0.0015686562987416,0.6040229885056813,0.0088781478240405,-0.7532930253176441,0.004279338103077,0.4686206896552505,0.0188897826061166,-0.6882703257963255,0.1089683007022967
1R0R,E288P,-0.4242528735632742,0.0029259590945327,-0.4585593430946856,0.0023356410293173,-0.8370114942529696,0.0981018153646115,-1.2021787447887249,0.0664740583416186,-1.4506896551723465,0.0018101167526401,-1.3363896217316096,0.004089212864078
1R0R,E288Q,0.0067816091953726,0.1369155144803837,-0.1805389217149983,0.1901336337708651,-0.5459770114943051,0.0030105289318897,-0.9474242913685478,0.0020502312542986,-0.7279310344826637,0.0001625532830275,-0.9427234822135104,0.0033492219603639
1R0R,E288R,-0.1359770114942781,0.1463957249505007,-0.6272829948658188,0.13450374610546,0.5806896551723508,0.0112631948720667,-1.1052749857511155,0.0192739007084908,0.1358620689655713,0.0688529733045811,-1.1113158041744675,0.0187486725430367
1R0R,E288S,1.2658620689654818,0.129393638563196,0.9150536482201952,0.0490093279751982,0.236206896551653,0.0087068491330756,-0.3813372059430444,0.0136352729371596,0.2189655172414546,0.0011378729812218,-0.4317385426726763,0.0003015463061654
1R0R,E288T,0.6647126436780973,0.1777614357001972,-0.7699087080664743,0.7695930958308113,0.4640229885056727,0.0961610871589013,-0.3847914771140416,0.0197721651994147,0.4140229885058357,0.0014629795472848,-1.0143901997437113,0.0143423696630045
1R0R,E288V,-0.9766666666667008,0.2841096124712063,-1.0736103848684326,0.0790518731158863,-1.0357471264368563,0.0754807553700545,-1.8032301302779767,0.2069269805906476,-0.7365517241378674,0.4631803697923816,-1.4446889886415393,0.3477287016479364
1R0R,E288W,-0.8649425287356687,0.0718913832591683,-2.3811933552030298,0.0866706831322892,-0.2378160919541229,0.0668093993259108,-2.450026668488143,0.3675447791561063,-0.7750574712643085,0.00181011675264,-2.2910336304038927,0.0044800968472827
1R0R,E288Y,-0.2232183908046246,0.001567607091605,-1.3538528868126043,0.1602384707917843,-1.1267816091954936,0.0671065550780519,-2.159314180185881,0.0792246886125674,-1.374367816091888,0.072823870798041,-1.8335751835662064,0.0046729523618502
1R0R,G301=,5.2273000742767785e-14,0.1746641644778876,,,-5.2263748884229244e-14,0.2940342668565599,-0.4272915730000242,0.1865586058789409,0.0,0.002113192679395,-0.0024806769603343,0.0009790205479657
1R0R,G301A,-1.3227586206896331,0.1156610873133675,-0.4698111977492363,0.0806942682539585,-1.7152873563219178,0.0076641761278822,-0.9119865958496906,0.0046263470090387,-1.1249425287356625,0.0001625532830275,-0.0460769451281824,0.0002255740703191
1R0R,G301C,-0.5134482758620279,0.0339487384894578,-0.5103603488184186,0.0848914149187626,0.0219540229884309,0.2960095284001474,-0.2484399428338413,0.1892849130717394,0.4131034482758418,0.000325106566055,0.7172106595223716,0.0054491236595956
1R0R,G301D,0.6412643678161647,0.0850270215766957,0.9671493874569432,0.0151747272974344,0.2956321839080071,0.0469812734835023,0.5916936036796686,0.1384345983679434,2.3693103448275927,0.000905058376325,2.8175316352121627,0.0061860784435617
1R0R,G301E,0.285287356321888,0.1963845494610215,1.2171151619620744,0.1508609386943435,-0.4560919540230493,0.3037496326659569,0.4230728360263369,0.1700478276740903,1.757011494252854,0.0014629795472848,2.8759083283812443,0.0015388017000873
1R0R,G301F,-2.251609195402266,0.0004300755617228,-0.9536338154981454,0.0312885087547853,1.4745977011493674,0.3838708427152345,-0.4479065870941406,0.9485695912035188,11.255862068965508,0.0021503778084751,7.849831467584205,0.0139079594743697
1R0R,G301H,-0.3717241379309996,0.0036817511213764,-0.6293986564787178,0.2807323659155283,2.1808045977010924,0.1388190761257819,0.8340655548215636,0.136332607978603,2.2832183908046013,0.0319569170937825,0.9632096236004898,0.2546685400533811
1R0R,G301I,-1.380689655172355,0.0872929292067667,-0.5828219091517111,0.0311359632040908,0.612643678160859,0.2200217983651686,0.1729515415511339,0.0175776245538475,2.5077011494252885,0.0004876598490825,2.7845821065314382,0.0031201391877567
1R0R,G301K,0.2580459770115601,0.0097097526813474,1.2013900403269548,0.0250039803945751,1.086091954022918,0.0127197294795722,1.711137654625802,0.0054456417583276,4.0748275862069,0.001874655911521,5.199309585524426,0.0035947369907805
1R0R,G301L,-1.910344827586168,0.1829149190686982,-0.9210837090757656,0.0906320698254323,-1.510114942528805,0.0507166243058141,-0.7983232812492802,0.1287864681746309,6.618045977011494,0.0007449127239736,5.573168936637207,0.0019371151792334
1R0R,G301M,-1.4296551724137263,0.1778055781539725,-0.6025489695176819,0.0858356627949345,-1.1336781609196251,0.0017880861133399,-0.6772700382630162,0.0010653284744389,0.6747126436781484,0.0025391634522308,1.8987425340865804,0.003877931512192
1R0R,G301N,-0.2017241379309947,0.001689303270877,0.0188340223020866,0.0067197908394411,0.5490804597700677,0.3489571501124746,0.6476105681819023,0.1133481236177568,2.02218390804596,0.000975319698202,1.9288172173770648,0.0042974166234342
1R0R,G301P,-1.0003448275861777,0.0927515700435442,-0.0729831830682902,0.0172075759939345,-0.8954022988506228,0.1386070598129395,-0.4620991506389297,0.1369282589360859,-0.0045977011494211,0.0021318663207898,0.2942374069029363,0.0031437970196408
1R0R,G301Q,-0.9094252873562736,0.1498056167730651,-0.0553965401373695,0.208533986364994,-1.531839080459796,0.0069708640000304,-0.9786519607465856,0.0049081477179849,0.971609195402296,0.0017203022467798,1.765262934917042,0.002978213379473
1R0R,G301R,-1.3159770114942086,0.1066866063408265,-0.1351233235976613,0.0620787263063464,0.3219540229884456,0.047005451653347,1.4603612122038412,0.0081658802761003,1.482183908045975,0.0007449127239736,2.6439767363824584,0.0152814670261784
1R0R,G301S,-0.9635632183907828,0.0036745672099289,-0.1129807758505079,0.1056919201206588,-0.8890804597701819,0.0004876598491196,-0.5412242097571672,0.0097472481989534,0.1083908045976992,0.0014629795472848,1.0841568978203318,0.0045304382162362
1R0R,G301T,0.0912643678161291,0.1058234357352043,0.1822963398642279,0.1080839523370481,0.5509195402298467,0.4564101075635502,0.9530203351858488,0.4369733289493686,1.0855172413793055,0.0022582623798252,1.71085014504013,0.0045512390798626
1R0R,G301V,0.5983908045977423,0.0842068369309582,1.4402675743808322,0.0143201467111778,0.6818390804597199,0.0061770247551946,1.3037976709771577,0.0053671018289518,2.0079310344827643,0.0018746559115582,3.080370215179755,0.0057809780818296
1R0R,G301W,-2.1401149425287,0.0654060358910432,-1.0820570570908057,0.079137541786503,2.761954022988453,0.0092698138637347,0.0201783215827513,0.005260663773324,3.5466666666666664,0.0459910897986006,0.8088314425575605,0.089228154378633
1R0R,G301Y,-1.978045977011449,0.001697106098901,-0.4935038525125481,0.0007972616957853,1.6498850574712172,0.1412146503983226,-0.0172020344643374,0.1050714551282569,-0.0250574712643763,0.1187592748323454,-0.700259197620972,0.1900657646948443
1R0R,K282=,-2.6136500371383893e-14,0.0911941303018116,,,-2.6134901173179483e-14,0.0001625532830275,0.0152251664825854,0.0017650051872488,2.613491020819758e-14,0.0022757459624226,0.084529412189092,0.0059689297576016
1R0R,K282A,-0.0808045977011726,0.0925035305143474,-0.2187681411970024,0.0309554852681897,0.0752873563217575,0.009590643698847,-0.2690240997109434,0.0012763586763408,0.0058620689655354,0.0032874367002671,-0.2689872303300223,0.0175772746531754
1R0R,K282C,0.081609195402303,0.0979433104388254,0.1186256459001255,0.0248538738746672,0.1212643678160208,1.3877787807814457e-17,-0.0194583236478545,0.0,0.2556321839080643,0.0037493118230425,0.1582018401674874,0.0022799181658467
1R0R,K282D,2.3999999999999866,0.0843510585004817,1.777812893051253,0.1305681709714638,2.7744827586206284,0.3156784756469609,1.5606524368927397,0.0734984640528697,2.6929885057471625,0.0,2.037212432635338,9.421134519356846e-05
1R0R,K282E,1.606781609195381,0.0968854386122681,0.8474017777440825,0.0266609533421604,2.0294252873562644,0.0066646846043141,1.0517980215812863,0.0086376426450945,1.7817241379310318,0.0015506594900267,0.8865110435078934,0.0019124085061251
1R0R,K282F,0.2647126436781475,0.0305600172099179,-0.540551679953662,0.016804273471549,0.3136781609194666,0.0,-0.6802953891071709,0.0,0.646781609195397,0.0009753196982022,-0.6970339199400947,0.0032043444916111
1R0R,K282G,2.2177011494252725,0.0008127664151747,0.2031302467232057,0.0055055441464129,2.2967816091953206,0.0,0.1051128297867057,0.0,2.232413793103451,0.0014448051827487,0.2134048084307344,0.0012222864210442
1R0R,K282H,0.3988505747126207,0.0934681377430567,0.1324778842519569,0.0254509540852777,0.8380459770114612,0.1953890462037307,0.1037170583656095,0.09901824833917,0.5958620689655137,0.000325106566055,0.1485330544404672,0.0015840077053864
1R0R,K282I,1.312298850574703,0.0011378729812298,0.62033739638487,0.0118582565344006,1.6505747126436667,0.0,0.77145575687186,0.0,1.6735632183908244,0.0008127664151746,0.619728126795398,0.0096085537952295
1R0R,K282L,0.6671264367815931,0.0952578882099609,0.5369772114214022,0.0307121047295805,0.3502298850573958,0.0,0.3913200007601236,5.551115123125783e-17,1.0747126436782029,0.0004876598490826,0.6315219505224127,0.0061338166246645
1R0R,K282M,0.4171264367815983,0.018702106666454,0.3780186270869465,0.0506672472868841,0.4532183908045697,0.0016497356430327,0.2094889471494826,0.0023885443993394,0.659655172413823,0.0013305559658426,0.4555675458236326,0.0061820286932672
1R0R,K282N,0.2298850574712382,0.0916118634146124,0.5259599150196831,0.0299963880769569,0.3333333333332653,0.0,0.3931904680688338,5.551115123125783e-17,0.2986206896551935,0.0004300755617159,0.4849074597338335,0.0043682081706296
1R0R,K282P,7.81103448275861,0.0919265763636146,0.2942645489799005,0.0187890157251877,8.21954022988503,0.0,0.4111213529478359,0.0,8.109770114942563,0.0006502131321471,0.243667745696555,0.0014148769819641
1R0R,K282Q,-0.5654022988506119,0.0916118634146124,0.1284354704511963,0.0054397415290884,-0.3408045977011922,5.551115123125783e-17,0.1786638691099785,0.0,-0.3449425287356294,0.0011262021805953,0.2869559222835176,0.0020037887585808
1R0R,K282R,-0.3118390804597661,0.0013004262642203,0.1984945921591112,0.0090816648343787,-0.3935632183908544,0.0,-0.0171109097536749,0.0,-0.0070114942528384,0.0012272503738043,0.0906795511845898,0.0015826959111931
1R0R,K282S,1.347701149425277,0.0010659331603991,0.8643007313404615,0.0131074838564589,1.6317241379309984,0.0001625532830275,1.094445726437047,0.0485148335167935,1.3667816091954377,0.0004876598490827,0.8514509728179919,0.0037504121882174
1R0R,K282T,0.3937931034482678,0.0975319698188193,0.1645753141041098,0.0296501463922223,0.435057471264325,0.0,0.0943290452822362,0.0,0.5054022988505672,0.0017582825908883,0.1621151205884824,0.0024038369233895
1R0R,K282V,1.2300000000000026,0.0941200353500726,0.2515209853020511,0.045232887143584,1.6124137931033722,0.1435345489167238,0.3698501444628634,0.0582476230137517,1.518850574712663,0.0034597510214611,0.1506323944749181,0.0119759173146325
1R0R,K282W,0.3233333333333451,0.093074637233682,-0.0057468504528044,0.0218162723246659,0.7765517241378624,0.2729801087637648,0.1084623337554399,0.0716347945406855,0.5212643678161014,0.0021989800539744,-0.031048789896912,0.0095574340441391
1R0R,K282Y,0.3159770114942556,0.0819453978147388,-0.1535821986532738,0.0474762921932324,-0.3070114942529315,0.0,-0.8499816136630779,1.1102230246251563e-16,0.6305747126437162,0.0002815505451407,-0.2237183399788382,0.0028814941143513
1R0R,L287=,7.840487518488241e-14,0.0302261699565732,,,-2.6131874442114622e-14,0.1297049916514248,-0.2944587912137409,0.0151298150182577,0.0,0.0,-0.0549233383088872,0.0
1R0R,L287A,1.569080459770175,0.0384647233861213,0.9358299366590734,0.0422192775155273,1.988620689655164,0.0585191818913211,1.1072992773988284,0.0017355295078381,2.211839080459816,0.0013004262642574,1.5884395590872415,0.0015886103127443
1R0R,L287C,1.7467816091954942,0.1512235734391184,0.9254308977187714,0.0438280505397397,1.9066666666666368,0.0454251361158926,1.0323019484099734,0.0032478700750903,2.2914942528735804,0.0006502131321471,1.4542034045190255,0.000478596808662
1R0R,L287D,2.958275862069053,0.0905776299197647,3.626511424919546,0.047905810501896,3.7506896551723976,0.2265656322818662,3.846751050878423,0.0764816038806167,3.8889655172414126,0.1921431376212194,3.963146977741925,0.0066457532996081
1R0R,L287E,2.7657471264368483,0.030240153843491,2.4802854512077133,0.0012053497508543,2.8678160919540283,0.0099157502649021,2.194683331001291,0.0009634943188373,3.63379310344828,0.1916536296381402,2.923512948102075,0.0004181630437748
1R0R,L287F,-0.6870114942528054,0.1445188279669661,-1.1576378940885503,0.1559325635092007,-0.8748275862069086,0.0058519181891025,-1.431254633719255,0.0044013613481543,-0.0968965517241465,0.0019506393963675,-0.353657312578816,0.0015271274824595
1R0R,L287G,3.264712643678268,0.028570097924971,2.8264338154584863,0.0218479572611027,3.836091954022965,0.0544553498155216,2.899036803111562,0.0066524357000279,4.079655172413812,0.1872613820521319,3.168915408321471,0.0035825835492078
1R0R,L287H,1.60091954022995,0.2304492501970135,1.1782890277332816,0.0493533583551107,1.8527586206896447,0.0565860563013371,1.370673748039837,0.1476643428958462,1.725747126436796,0.1920629465891282,1.4792200339383763,0.0028184918397702
1R0R,L287I,1.614022988505816,0.0,0.6035088547252662,0.0,2.972068965517212,4.440892098500626e-16,1.8876922179770736,0.0,2.178275862068968,0.0649198414242163,0.9762054927982092,0.0150628026222492
1R0R,L287K,3.2217241379311123,0.1461812310300368,3.037928557565549,0.121634559818069,3.5060919540229807,0.2526963328770159,3.1042829191896373,0.0536290195922676,3.5020689655172763,0.0385251280784524,3.3849334779986378,0.0078430129141641
1R0R,L287M,0.7005747126437597,0.1019212973433843,0.3163512090856168,0.1370608430822105,1.0104597701149356,0.0084527707176171,0.4212085106978154,0.0016227183892119,1.605632183908052,0.1518247663513135,0.9078072663243708,0.0026580698131236
1R0R,L287N,1.316436781609297,0.2014902859075246,1.7623046052370688,0.1529346876247747,1.81045977011494,0.0435642798523803,1.9789835184221227,0.0032242870143471,2.1520689655172363,0.1414844016477946,2.354247461700897,0.0164697111992003
1R0R,L287P,6.238850574712725,0.0007449127239374,5.694396605822032,0.0102752670854082,7.370919540229853,0.0087522527911715,5.039680385985821,0.0127237952585906,5.862643678160932,0.0040048853770544,4.12776422122706,0.0192975142283582
1R0R,L287Q,1.5686206896552433,0.0343091414718043,1.6386054169046391,0.0036439753956662,1.4714942528735524,0.2761780278703063,1.3940187912420772,0.0090912655079431,1.6708045977011563,0.1549155814078313,1.3001985856227951,0.0039791228283166
1R0R,L287R,3.6125287356322726,0.0301618481774696,3.3991220704338416,0.0235751366574841,3.371609195402282,0.2466164746312038,2.888714532372127,0.004858737617446,3.641149425287369,0.1819788904086425,3.3371916448564227,0.0077154699717198
1R0R,L287S,3.192643678161005,0.3024125479993524,2.902758154324283,0.2316518376342689,3.399310344827594,0.1458105667071274,2.94287122465294,0.0390962265625555,3.4840229885057385,0.0342987427196254,3.3681916220340704,0.0087253555264464
1R0R,L287T,2.401379310344938,0.220052480558676,2.3624990461816795,0.1583774156608756,2.5136781609195045,0.006014471472167,2.5154369086671795,0.0026979573258089,3.015632183908058,0.0037493118230394,2.629622636846166,0.0017532035677499
1R0R,L287V,1.4594252873564135,0.2486440968676073,0.4369465146794875,0.14190458811258,1.30919540229881,0.0045514919248689,0.3184114900875164,0.0070568007078887,1.355747126436764,0.132291710164117,0.4263254738185716,0.0187725860565072
1R0R,L287W,0.322298850574801,0.2119286518338142,-0.6793487490718407,0.1301241622379426,0.5004597701149213,0.0077737188132689,-0.9434741098148388,0.0022883138595532,-0.1002298850574794,0.193926271040181,-0.5342424595826104,0.0175458351719428
1R0R,L287Y,0.026091954023051,0.0746714298350766,-0.3019722812585565,0.0435543531203961,-0.2925287356321922,0.0104034101140216,-0.6815367746371025,0.0085302042568062,1.1979310344827354,0.0,0.5456223579180287,0.0
1R0R,N297=,-7.840473062459274e-14,0.0012272503737676,,,0.0,0.0,-0.0059330042729313,0.0,0.0,0.0,-0.00337859414991,4.336808689942021e-19
1R0R,N297S,1.0659770114941354,0.0044901206861248,0.0002022363495096,5.604757414399561e-05,1.108965517241343,0.0,-0.0061448735675639,0.0,1.0789655172414252,0.0,-0.0035470627142723,0.0
1R0R,N305=,5.2273000742767785e-14,0.0972882417446712,,,-2.8912057932946783e-19,0.0049090014951808,-0.6259079043322617,0.0120253451483445,0.0,0.0,-0.0482735297147632,0.0
1R0R,N305A,-0.3004597701148679,0.0013004262642573,-0.166839300931179,0.0961446680065439,-0.197011494252893,0.0112807762265607,-0.665608150043305,0.0088031257773512,-0.1622988505746904,0.0022757459624595,-0.0780802281515311,0.0041896037575349
1R0R,N305C,0.2595402298851141,0.1125365429999013,-0.2416492565067664,0.0862264841727494,0.4206896551723971,0.3330746519049257,-0.7597269806552797,0.0592297495935521,0.2389655172413737,2.775557561562892e-17,-0.2455003876480077,0.0
1R0R,N305D,-0.1008045977010917,0.0979060731234029,-0.0827418475224717,0.1033004385831283,0.1505747126436457,0.0029304709848156,-0.6631440699592447,0.0123581395894996,-0.2193103448275749,0.0004876598490826,0.093943241964375,0.0006430605246651
1R0R,N305E,-1.00310344827582,0.0021256600010371,0.1799367768132375,0.0043761240123197,-0.8135632183908278,0.0476630508427688,-0.536607890460045,0.1512261212143945,-0.7955172413792638,0.0027151751289783,0.2921074391264451,0.0024720594365521
1R0R,N305F,-2.051839080459731,0.1692730799951511,-0.535886989031256,0.1115438564284221,-1.2513793103448736,0.0024055689122431,-1.6314085735998247,0.0060936822627931,-1.5593103448275638,0.0009753196981652,-1.2839338382142766,0.0028342227438941
1R0R,N305G,1.2212643678161443,0.096498480119346,-0.0338564290290503,0.0993725681348426,1.1542528735632087,0.00788509098214,-0.6028159636585201,0.0109761272969704,1.322413793103461,0.0009753196981652,-0.0071313485127523,0.0013751603838584
1R0R,N305H,-0.9128735632183133,0.0920671717649293,-0.4697433106634471,0.0895748874132918,-0.2871264367816408,0.3355775817654322,-0.941155437302946,0.0679954720719356,-1.3822988505746685,0.0013004262642573,-0.1379858553455364,0.0058578914736412
1R0R,N305I,-1.7186206896551202,0.1894584141327106,-0.4884815738518196,0.1123157721875981,-1.61482758620692,0.3311221148377217,-0.950616597958115,0.0648814933152668,-1.8220689655171995,0.0,-0.530013669409637,0.0
1R0R,N305K,-0.1880459770114121,0.09531736975847,0.0323255123784104,0.0977501459720704,0.0224137931034148,0.0092698138637717,-0.3378367997051303,0.0094369937551225,0.9025287356321942,0.0006502131321471,0.8231695693374886,0.0050434772659075
1R0R,N305L,-1.922873563218344,0.0942190856175062,-0.6288529764952497,0.0901975821383101,-2.318620689655201,0.0130943707213907,-1.1838321476156823,0.0056672548488125,-2.322068965517216,0.0,-0.7591004294286465,0.0
1R0R,N305M,-1.2248275862068123,0.003197799481203,-0.5815152274250465,0.0830625608342856,-1.5873563218391002,0.0011378729811928,-1.176486347948629,0.0131910165653778,-1.4447126436781563,0.0034977296677389,-1.0411958009159397,0.0028250511132725
1R0R,N305P,2.257126436781656,0.0016971060988709,0.2102718573892214,0.0015405382627756,3.952988505747136,0.0057032810253111,-0.3641429159183226,0.0043054650850927,4.230689655172468,0.001489825447911,0.170783779320421,0.0018387938622737
1R0R,N305Q,-1.2426436781608583,0.0954337297622158,-0.3611682715409345,0.016698633467545,-0.7819540229885447,0.3223256174629551,-0.6657607670569172,0.0634569036736023,-1.003563218390778,0.00366376493116,-0.206537027535558,0.0055160227696407
1R0R,N305R,-0.0362068965516781,0.0451105129972824,0.0633085145365588,0.030255029667632,-0.552183908045987,0.0078850909821518,-1.0876910199696492,0.006739672225369,-0.0689655172413165,0.0,-0.2487232403803256,0.0
1R0R,N305S,0.4318390804598295,0.1672429987676997,-0.0698618188323377,0.1121453699685685,0.4614942528735224,0.0025235055632071,-0.6066028057459554,0.0011934560377377,0.7009195402299063,0.0022757459624595,-0.0449713263219825,0.0022520075153661
1R0R,N305T,-0.2944827586206257,0.094133510064175,-0.2405848358463358,0.0906216893986192,0.127701149425247,0.007202046067962,-0.6846921602745635,0.0098154399822213,-0.0668965517241241,0.0,-0.1406848328204056,0.0
1R0R,N305V,-0.9348275862068488,0.0992915850736054,-0.2088148749543632,0.0892610598740819,-1.0650574712643766,0.0081714356722651,-0.831178136650986,0.0121233705545107,-1.0433333333332808,0.0003251065660551,-0.293798467548954,0.0011319911087717
1R0R,N305W,-1.9712643678160504,0.0959927717805537,-0.9321563541754124,0.1029307773206363,-1.9155172413793329,0.0020302898543424,-2.150288342834576,0.0159818368979558,-1.8520689655172216,0.0027151751289418,-1.6955248584222111,0.0115984218866485
1R0R,N305Y,-1.861264367816012,0.1492306424562502,-0.5309662434766669,0.2112004362050031,-1.2001149425287394,0.1341239934056615,-1.2782983416899432,0.2591081294369628,-1.321954022988477,0.002113192679432,-1.169093580141995,0.0003272436310969
1R0R,P283=,2.613491020819758e-14,0.0014171066673495,,,0.0,0.0,-0.0045271678780816,0.0,-2.613491020819758e-14,0.0008601511233759,0.0735671295989238,0.0014189564431036
1R0R,P283A,0.8224137931034973,0.0011378729811928,0.1371855759907964,0.0019096534636649,1.3096551724137937,0.0,-0.2004252801837004,2.775557561562892e-17,1.1645977011494064,0.0015506594900268,-0.1926269539651274,0.0038703999407265
1R0R,P283C,1.5110344827586422,0.0011721883939375,-0.3677536624995705,0.0047420928899835,2.003793103448249,0.0,-0.3773234932619853,0.0,1.7345977011493872,0.0008127664151376,-0.5046811974313808,0.0054237756636174
1R0R,P283D,-0.2363218390804121,0.0030454347814913,-0.4572916418088352,0.0029540096732298,1.4606896551723711,0.0,0.4050402239106225,0.0,1.1486206896551392,0.0030367459341676,0.1067691360636128,0.0055085337173967
1R0R,P283E,0.0454022988506248,0.0004876598491196,-0.544336301344153,0.0037876227367341,0.281724137931037,0.0,-0.4396805730390623,0.0,0.1816091954022904,0.0,-0.4689245231645992,5.551115123125783e-17
1R0R,P283F,0.920804597701198,0.0001625532830645,-0.3136396191645621,0.0043047893455077,1.2320689655172734,0.0,0.306745070362279,0.0,1.046666666666666,0.0003251065660551,0.0177568426641133,0.0010606889397123
1R0R,P283G,1.8448275862069168,0.0030105289318788,0.7753057683184931,0.0022705130130574,2.496896551724133,0.0,0.7473378823427256,0.0,2.492988505747084,0.000975319698202,0.6097708191898698,0.0004306642304382
1R0R,P283H,0.739885057471331,0.0019506393963675,0.0567303258476229,0.0028316184595287,1.3444827586206507,0.0,0.2370946042703022,2.775557561562892e-17,1.2482758620689538,0.0003251065660921,0.2101905156689162,0.0014420371312369
1R0R,P283I,1.0375862068965829,0.0039450580004012,-0.8279185543254233,0.003429334742595,1.9519540229885284,0.000325106566055,-0.4589166639322486,0.0011782939654913,2.1166666666666365,0.0017880861133399,-0.4832331505289319,0.001996758350608
1R0R,P283K,0.7590804597701458,0.0049197550710587,0.4082789752028841,0.00814584864992,1.2582758620689267,0.0,0.225768264454175,2.775557561562892e-17,1.128275862068943,0.0026008525284777,0.1850367519819235,0.0018129839855389
1R0R,P283L,0.0496551724138472,0.0021869307575319,-0.4619635433892006,0.0018773346708607,0.7434482758620514,0.0,-0.550687768357828,0.0,0.876896551724101,0.0025391634522331,-0.2177901870834506,0.0021863513323945
1R0R,P283M,0.735057471264418,0.0034136189436761,-0.0742164566308302,0.0007793805842027,1.1093103448275417,0.0,-0.5508565933047098,0.0,1.3873563218390472,0.0030885123775973,-0.383728286367726,0.0055715276555391
1R0R,P283N,1.071264367816111,0.0021989800539743,0.5324587050628237,0.0016626958729972,1.5644827586207015,0.0,0.2135660976843751,2.775557561562892e-17,1.4936781609195016,0.0035278182191452,0.2219577346698409,0.0039603801826276
1R0R,P283Q,1.071494252873603,0.0011378729811928,0.0183170523278335,0.001299964094716,1.1882758620689355,0.0,0.1371320377139564,0.0,1.052988505747081,0.0024055689122132,0.0493801352255449,0.0042670242409645
1R0R,P283R,0.8358620689655357,0.0015506594900267,0.0402939010584419,0.0020809117757248,1.2631034482758658,0.0980196296679389,0.134334725808408,0.1144947111231181,1.536436781609191,0.0224323530583188,0.243631453421946,0.0078264846178064
1R0R,P283S,1.015287356321875,0.0068175552305077,1.0393217005685855,0.0193142530972505,1.6920689655172156,0.0,0.7063401364510763,0.0,1.5636781609194923,0.0014629795472849,0.6279369441426753,0.0014534871725911
1R0R,P283T,0.7727586206897024,0.001388855859001,0.6043835020544578,0.0011580307738801,1.7365517241379511,0.0,0.7243827082401492,1.1102230246251563e-16,1.5219540229884518,0.0017126051064045,0.3108782721414559,0.0006018031737232
1R0R,P283V,0.9809195402299494,0.0004876598490826,-0.9302110670908394,0.0014742786778048,1.1996551724138076,0.0,-0.6679939125987842,0.0,0.9601149425287172,0.0011721883939375,-0.808214085107246,0.0016101637994656
1R0R,P283W,0.6712643678161087,0.0,0.3490913315785888,0.0,1.5108045977011235,0.113322374793689,-2.084093543701172,0.0980197934309909,0.1122988505746967,0.0009753196981652,-0.146423791160952,0.0001658012411287
1R0R,P283Y,0.7673563218391249,0.0008127664151746,-0.2067334877132526,0.0007053700312196,1.374137931034448,2.220446049250313e-16,-0.2169901196017345,0.0,0.5119540229884739,0.0017126051064045,0.0194899756943205,0.0022509862893393
1R0R,R290=,2.6136500371383893e-14,0.061455675943688,,,-2.6127248512845352e-14,0.1844173980969055,-0.4943878809401615,0.015962952849478,-7.840473062459274e-14,0.0011378729812218,0.0374443569120265,0.0038225181409761
1R0R,R290A,0.5421839080459884,0.0792508522493115,0.0582731971347642,0.0890542540014119,0.5064367816091634,0.0813078457559907,-0.4254986742860549,0.0697358864117002,0.8532183908045196,0.0,0.0944526695629399,0.0014317159829439
1R0R,R290C,0.6129885057471621,0.0809164380282912,0.1695030483974681,0.0882315763245834,0.4998850574712305,0.0804034285493921,-0.4895207824518695,0.0689011632042174,0.9208045977010936,0.0029663190575976,0.0581708650659639,0.0035314064347159
1R0R,R290D,0.4955172413793536,0.0641146499170981,0.1012216698355827,0.112335759071146,0.5404597701149424,0.1944181436641529,-0.46141020145513,0.0526556116094309,0.7687356321838413,0.0014077527257361,0.0871259867001273,0.0037693120628217
1R0R,R290E,1.192758620689702,0.135140253426534,0.1797922868482946,0.0795702422871498,1.219425287356287,0.1168319422711179,-0.3748839824566235,0.1972539321489899,1.3371264367815614,0.0009050583763383,-0.0199160847479765,0.0212314165197667
1R0R,R290F,-0.0071264367815974,0.0993346873103847,0.1680288250682763,0.0059886535257344,0.4148275862068878,0.2984027148146325,-0.6451689348465993,0.4957147447277731,0.7957471264367295,0.1262547278664015,-0.6879984057012599,0.5474625481828729
1R0R,R290G,2.358160919540239,0.0809399464865351,0.2249101603417236,0.0059299372140916,2.329310344827572,0.0159177765735447,-0.4466616863594246,0.0708013952758301,2.4580459770114147,0.0054303502579201,0.0795390012937484,0.0144845597329465
1R0R,R290H,0.3795402298850991,0.0937247609924454,0.1842377060746201,0.0014627922329482,0.2870114942528556,0.0961024027757001,-0.420585652599396,0.0589063502919216,0.5720689655171994,0.0071578838974352,0.0985268236931706,0.0113029920863296
1R0R,R290I,0.1006896551724372,0.1414015495077846,-0.1018293010048475,0.0829278445295242,0.5960919540229533,0.1136524150615681,-0.7047449942149081,0.1098003142697819,0.7491954022987755,0.0010659331604132,-0.0629677844753832,0.0010023692870078
1R0R,R290K,0.4048275862069413,0.0787488033282533,0.0514069045285636,0.0927166530994624,0.6247126436781547,0.0212646784693149,-0.2769426424364918,0.1299816010743876,0.5283908045976204,0.0004876598490826,-0.103776256391625,0.0018155272896611
1R0R,R290L,0.3150574712643922,0.0963011252519829,0.0496501536296776,0.0090968964125279,0.4074712643677983,0.0260146203189375,-0.6644891030366606,0.1310887057910957,0.4342528735631684,0.0022347381718724,-0.1808519944002889,0.0043375343228588
1R0R,R290M,0.7477011494253261,0.0966616779501972,0.0354461281694548,0.2310681290373277,0.6003448275862019,0.0381771880569782,-1.0998889858999048,0.1280466638104934,0.4904597701148702,0.001567607091605,-0.6808190469831156,0.0053207514169663
1R0R,R290N,0.1209195402299266,0.1023115063849167,0.2247921704700526,0.0155310622302883,0.0895402298850309,0.0857719294810709,-0.4242970451910935,0.0657778373715935,0.4320689655171646,0.0006502131321101,0.0733776992539484,0.0015868340588682
1R0R,R290P,3.437816091954061,0.0149654995850449,0.4096766248936473,0.0119087990748272,3.7043678160919353,0.0605591159663076,-0.0249180505922867,0.0065866323006046,4.051839080459716,0.0005631010902817,0.1969584055659809,0.0018566118278745
1R0R,R290Q,0.2635632183908706,0.1423710659235479,-0.1511001078772055,0.1468827271788778,0.3326436781608941,0.0382394290034054,-0.3868913467408283,0.1290763538208282,0.6401149425286526,0.0012902266850919,0.030622468891971,0.0020268165495782
1R0R,R290S,0.6966666666667098,0.0992756165331943,0.1679235909824226,0.0876371113915109,0.6241379310344639,0.0898919655163768,-0.3999407209612557,0.0645065397573335,0.927816091953958,0.0017880861133399,0.1102595289244059,0.0033866825246209
1R0R,R290T,0.7513793103448577,0.0640855881665377,0.0692701297160725,0.0056230118480553,0.6610344827585918,0.0328828055490796,-0.4832307099829172,0.1268358074618211,0.8240229885056537,0.0001625532830275,-0.0227095271625016,0.0017148922463255
1R0R,R290V,-0.0745977011493861,0.0071744765674845,-0.0802618770744525,0.1476218764339169,0.3112643678160493,0.1185887197406652,-0.6370197484104874,0.0645083572062087,0.4265517241378541,0.0005860941969867,-0.0350553734239744,0.0020083129911564
1R0R,R290W,-0.1029885057470693,0.0540320364152063,0.0855616449019379,0.0697013686834728,-0.2122988505747365,0.053195173804142,-0.4812420216001754,0.0666049596473291,-0.0043678160920336,0.0127911979248348,0.1323973112630222,0.0163570310917236
1R0R,R290Y,-0.2497701149424767,0.1000361937407487,0.202280587663645,0.0053413513297766,0.052643678160903,0.0232007444038109,-0.333834818916552,0.1699776449156488,0.7244827586206241,0.2471632691076511,-0.3671889623077387,0.3706602126136099
1R0R,T286=,-1.045413755562663e-13,0.0873688738713447,,,0.0,0.0036745672099289,-0.291942919480572,0.003299916760997,-2.6136500371383893e-14,0.0814391947987226,-0.0042257233794719,9.378591393186848e-05
1R0R,T286A,-0.3204597701150745,0.0952440177083826,-0.3303902545419611,0.0404209489599001,0.1898850574712955,0.0002815505451408,-0.2823463494280793,0.0024017187380982,0.6088505747125944,0.0037387255097444,0.1760215228051001,0.0399066858905978
1R0R,T286C,0.2402298850573573,0.0091276237683263,-0.484988734151583,0.0220691644110077,0.4456321839080666,0.000325106566055,-0.7460856140824035,0.0047876177049657,1.074252873563167,0.2415412155422918,-0.2113517153108774,0.0929837022012129
1R0R,T286D,1.5226436781607973,0.1929323955043425,2.160336334705612,0.1014566354614762,3.018505747126433,0.4570208896094738,2.249466049870352,0.2489335438880794,2.597701149425225,0.0398593776020938,2.064843641298895,0.1685563200443074
1R0R,T286E,1.671264367815957,0.2008094993118513,1.8961102128503564,0.0477477559465841,2.36747126436784,0.1183560935612483,1.9474041912540272,0.1362402042026911,2.457931034482708,0.0021989800539742,2.2361314087945554,0.0057680719281856
1R0R,T286F,0.0475862068964195,0.0008127664151377,-0.7671302200115527,0.0746689387344826,0.4591954022988903,0.0900429280630776,-0.6339993301636612,0.0241662520629788,0.757816091953953,0.0381501854450492,0.1144783687734694,0.0075404810985936
1R0R,T286G,1.481264367815955,0.0648025141049535,1.057165763616274,0.0821944457787259,1.979080459770124,0.0031645746892036,1.0467963497524648,0.0079125877591753,2.141609195402254,0.0030885123775972,1.571988428241984,0.0064933368483162
1R0R,T286H,0.6858620689653979,0.0105959307370196,0.3409878152209284,0.0108735537715415,0.8736781609195532,0.0122044935617679,0.6137725085429584,0.0087708376253769,1.0775862068964994,0.1510615102044445,1.1394645459068442,0.2117981834925409
1R0R,T286I,-1.4003448275863368,0.1510728795294564,-1.3980253155267717,0.0760657175447506,-0.7564367816091844,0.1349380249498142,-1.457186820846986,0.0276641037646063,-0.4939080459770666,0.1967130479982107,-1.1002134572449591,0.0471801460148212
1R0R,T286K,0.4511494252872204,0.0834721792179462,0.4298813524426272,0.08229432507717,1.4190804597701678,0.1776096030416553,0.9024579548373636,0.1362876621640827,2.4402298850574216,0.0265201085596001,1.573009750290734,0.2937708854237366
1R0R,T286L,1.1381609195401043,0.2226844116809908,0.0693570979528258,0.1089879359880207,0.6882758620689721,0.3833850453668525,-0.2319816225454899,0.1868593631092307,1.3324137931033813,0.359467281014131,0.1319680368628357,0.4393319668575211
1R0R,T286M,-0.7943678160920914,0.1812488787032175,-0.876938471561469,0.0279823241539726,0.4418390804598021,0.1447931905881518,-0.3381087755463408,0.0377904400276435,0.8614942528735247,0.1364071954674594,-0.299234227150741,0.0718792296424167
1R0R,T286N,1.2624137931033117,0.2142468920284032,1.1731128656512853,0.0857523968398719,2.0285057471264527,0.004933164076733,1.0166015955963763,0.0057902084363702,1.9450574712643185,0.0221269592414571,1.1566649185878586,0.1541717625232142
1R0R,T286P,6.491609195402179,0.0685406452806858,5.244054234465135,0.0966515427209244,6.443563218390828,0.129862982561069,4.799237451305928,0.0135469218197238,6.9116091954022565,0.0742633706682677,5.08997834982788,0.0854879118564555
1R0R,T286Q,-0.5520689655173848,0.0849771288776506,-0.2517603796703346,0.0964437343933916,0.1880459770115166,0.1271986450785444,-0.3523545922543438,0.0051915425139149,0.5706896551723782,0.0638989491582648,-0.1884930754509623,0.1208260857566278
1R0R,T286R,-0.4231034482759974,0.0793624682959753,-0.2243175787149167,0.0889306912502859,1.2716091954023108,0.0083093193434105,0.8298611771645734,0.0230842997478941,1.6613793103447698,0.0018462503912788,0.8965343360638541,0.0064963068644923
1R0R,T286S,0.4471264367814638,0.0185396277274871,0.9025076292343184,0.0345063084808472,0.9613793103448312,0.0012695817261165,0.9752968650532866,0.0111837082977871,1.0695402298850123,0.3098553398213667,1.1888134457352988,0.1233707179098231
1R0R,T286V,-0.8944827586208118,0.0669174829994314,-1.2830551884699477,0.0552982667159162,-0.4670114942528591,0.0020302898543157,-1.1411552282265411,0.0052676473289126,0.1952873563217947,0.1187734025447817,-0.6557403066481703,0.0296510907075653
1R0R,T286W,0.747931034482635,0.113787646449911,-0.3940492135961904,0.0345305130290504,5.094597701149436,0.0723559338271289,1.317857720029101,0.1135025347496951,0.8995402298850076,0.4297101801776917,-0.5271865937958927,0.1815562705020817
1R0R,T286Y,0.933908045976907,0.1820918945274037,0.0639399374086031,0.0700776677237084,0.6783908045977324,0.058424508328862,-0.404091410295675,0.0196729669858303,0.9579310344827132,0.0035165651818023,-0.1629463826406334,0.0030056657083513
1R0R,Y289=,-1.1564823173178713e-18,0.1176235600944143,,,0.0,0.002820194056646,-0.5204531231093491,0.000598587248645,2.613491020819758e-14,0.0073975139814675,-0.017863033579608,0.0059295699012507
1R0R,Y289A,2.6545977011494286,0.2346404135316541,0.9486590310618978,0.071100034805882,2.584367816091971,0.0005631010902815,0.9724635790222949,0.0016867730795551,2.50942528735636,0.0141028440418241,1.2453258601259936,0.0201944061792896
1R0R,Y289C,2.8121839080460176,0.0953675327873618,1.1860124076022542,0.0964310587994471,2.638620689655188,0.0016255328303123,1.1572337525410472,8.466483980015963e-07,2.5539080459770696,0.0009753196982022,1.469289370238062,0.0030435786240286
1R0R,Y289D,3.299080459770167,0.1602349147448517,2.6074529186722883,0.1829875249413397,3.5805747126436853,0.3233195832503654,2.686739448007163,0.1232679023372495,2.563563218390817,0.0004876598490825,2.423268383144461,0.0011789661054896
1R0R,Y289E,3.77965517241385,0.2901267826427018,2.862219459110429,0.2472398417568121,4.361724137931022,0.1254911345002226,3.256393029611884,0.0093102982101219,3.2086206896551945,0.012529262880395,2.6162182031814005,0.0009548922588682
1R0R,Y289F,0.0318390804598012,0.1587473257613456,-0.2161487604283807,0.0775347978970753,-0.206666666666693,0.0068272378873047,-0.2281211659178735,0.0036971236517022,-0.1768965517240842,0.01333234241266,-0.0266398405442121,0.0026274948018648
1R0R,Y289G,5.476321839080486,0.2442620958367148,2.5473400887340856,0.1546887600440797,5.566091954022983,0.3113746642389702,2.950137951119563,0.1002939973585234,4.898735632183925,0.0107432840878643,2.814653392609467,0.0012405242764877
1R0R,Y289H,1.94781609195404,0.110780151831908,1.0175911733560874,0.1506988317369651,1.7005747126436863,0.0019708538160589,1.000057042416359,0.0053002528052936,1.5697701149425465,0.0122498756333308,1.1695672335835736,0.0040967795174205
1R0R,Y289I,4.917356321839127,0.2766415710960765,2.8871410002536595,0.7318628686263573,4.433563218390792,0.7011776704316656,2.237323739335136,0.0954262511352585,3.259080459770146,0.2891206068874698,1.824209030013788,0.665057410140184
1R0R,Y289K,4.058160919540235,0.0768877028738405,2.684565598546941,0.131636130014606,4.370574712643691,0.106821998473638,3.0605690835877617,0.0352201827227945,4.109425287356369,0.0017582825908881,3.299355725822775,0.0048098472399217
1R0R,Y289L,2.820000000000038,0.2138487753494541,1.4794193227370065,0.2231805790739328,2.294942528735646,0.0001625532830644,1.4624245424862556,0.0019527470541201,1.819540229885101,0.0025391634522307,1.6483260043372574,0.0038187419481787
1R0R,Y289M,2.361724137931064,0.0607290450368149,1.0583347271165036,0.1822341044173096,2.381264367816103,0.0019708538160223,1.238074043133202,0.0024960195288684,2.040689655172456,0.0004300755617228,1.3321596356137952,0.0147285988458165
1R0R,Y289N,2.487241379310359,0.3232423839625696,1.5284376366124803,0.0480109234136367,2.5956321839080587,0.2634239522582203,1.7285172121210737,0.118600059432611,2.2410344827586552,0.0130923526323852,1.891044288618392,0.0007557474850386
1R0R,Y289P,9.708965517241417,0.0123572573823898,5.460147130874503,0.0596933725613995,10.212413793103442,0.0185168097154936,6.005216371643005,0.0945099287917475,8.926781609195457,0.5809551317508544,5.230647969914906,0.1884075473066698
1R0R,Y289Q,2.9903448275862683,0.0991674951753498,1.7768721705052988,0.120786131473334,3.1349425287356456,0.0286259977536279,2.243483822056825,0.036038387096755,2.5471264367816446,0.0111429060214935,2.1359324146602514,0.0039696314302377
1R0R,Y289R,2.356781609195444,0.0804453188992567,1.3223412678980404,0.0478705317630802,2.4164367816091854,0.1123767656386773,0.9518028116728036,0.1980064196053823,2.3235632183908472,0.0076226917846276,1.5544272978730016,0.0041188896509345
1R0R,Y289S,3.548505747126471,0.1290685350834345,2.375926236012748,0.0864155156103366,3.4179310344827445,0.1225913665381285,2.29390954502949,0.0080017563236982,2.948390804597761,0.0137268523856244,2.429017094318206,0.0011829347331425
1R0R,Y289T,3.8395402298850834,0.1629256724370469,2.468132043159313,0.1299797042036552,3.610804597701149,0.1259007445957387,2.521756883041512,0.00898923164715,2.8033333333333474,0.0157676684540415,2.426484921797468,0.0020760199937502
1R0R,Y289V,2.198045977011526,0.0312216577776802,0.9902979323274148,0.0548439663556743,3.0054022988505937,0.1825157788041352,1.0781523382635227,0.0682714401753491,1.4631034482758671,0.0001625532830275,0.9067134613189212,0.0051969251791706
1R0R,Y289W,-0.4251724137930853,0.0431951514921983,-0.477500303581418,0.0301056893766323,-0.401609195402289,0.059657054872514,-0.9374483140960632,0.0365515982059412,-0.3278160919539809,0.0126791560764442,-0.4800803807429945,0.0016454365314068
1CHO,A250=,0.0,0.0,,,-5.226982041639516e-14,0.0021131926793893,0.0379470846513445,0.0014160448292262,-7.840471567008005e-14,0.0,0.0670790888097113,0.0
1CHO,A250C,0.3627586206896754,0.0029663190576279,0.0591725595809921,0.004115799257965,0.388505747126397,0.0,0.1169103516918249,0.0,0.292068965517156,0.0004876598490826,-0.139391220709565,0.0007914507016777
1CHO,A250D,0.6556321839080664,0.0123892904199258,-0.0621232746029766,0.0154369832709992,0.9362068965516698,0.0391004005921248,0.3956731757254429,0.0182606454131003,0.8625287356320946,0.2207473583566193,0.6138378960920964,0.1284223902384135
1CHO,A250E,1.058160919540245,0.0065021313212866,1.2502585942085414,0.0004503638537359,1.1762068965516397,0.0185830469523671,1.297053487127866,0.0978940096667374,1.174252873563154,0.0006502131321471,1.5467676008460194,0.0028675831685438
1CHO,A250F,-1.555517241379299,0.0,-1.329511464581362,0.0,-1.985057471264418,0.0026160475118947,-1.727309367398061,0.0046926047288663,-2.042873563218459,0.00065021313211,-1.6032744165715025,0.0012447104692947
1CHO,A250G,1.86620689655171,0.020090954497886,1.1060786400089822,0.011503255799557,2.023448275861995,0.0030885123775974,0.9324377742926236,0.0067044177329216,1.6162068965516891,0.0,1.1209171506743587,0.0
1CHO,A250H,-0.2403448275861948,0.0153774031083652,-0.0586170290083065,0.0025945977372077,-0.5445977011494839,0.002454500747572,-0.2643100138431467,0.0034236651154548,-0.3128735632184408,0.0013004262642203,0.022911676188524,0.0068311980725864
1CHO,A250I,-0.9517241379310052,0.0029259590945697,-1.0452475552720826,0.0118427694450103,-1.618390804597719,0.0,-1.5674303106348182,0.0,-1.0990804597701818,0.0011378729812297,-0.8617422285659102,0.0087624050573872
1CHO,A250K,0.5271264367816106,0.1255179781882246,0.8532108156545627,0.0759704625603521,0.8063218390803929,0.0011378729812297,1.1040815539886732,0.0031144175125744,0.3834482758619921,0.0029259590945327,1.0651117033765216,0.0444866362816872
1CHO,A250L,-1.3882758620689628,0.0014629795472849,-1.3820209370503067,0.0157691646615014,-1.5460919540230174,0.0013888558590377,-1.4499069445823751,0.0064814512455212,-1.805862068965597,0.0004876598491196,-1.3068379413517903,0.0065701598315416
1CHO,A250M,-1.0958620689654772,0.0,-1.3550005284266011,2.220446049250313e-16,-0.099540229885108,0.0033825147056615,-0.5282656192094892,0.005851226087429,-1.3296551724138697,0.0,-1.2368387338016154,0.0
1CHO,A250N,0.5834482758620715,0.0,0.3587248698408201,0.0,0.5175862068964914,0.0035203201910729,0.4341815014697136,0.0045937807006221,0.5889655172413297,0.0,0.7177150011595023,1.1102230246251563e-16
1CHO,A250P,1.945517241379329,0.0,-0.013302792242406,0.0,1.619655172413755,0.0026008525284777,0.1243384742148942,0.0138189870117288,1.393563218390729,0.0001625532830645,0.3839783863335909,0.0062744304589405
1CHO,A250Q,-0.2950574712643425,0.0011378729812297,-0.2365437276170917,0.0028597126273899,-0.1911494252873837,0.0012272503738043,-0.1331281888862064,0.0052923326461951,-0.3279310344828445,0.0,-0.0061659180687456,0.0
1CHO,A250R,-0.9210344827586376,0.0,-0.089855862882767,1.3877787807814457e-17,-0.5973563218391461,0.0004876598491196,0.1984643561576606,0.0041428931455856,-0.5780459770115461,0.0001625532830275,0.1388807608462481,0.0406429577266766
1CHO,A250S,0.5055172413793524,0.0,0.880549490262434,0.0,0.4690804597700778,0.0015506594900268,0.930017301517475,0.0056352077024677,0.4341379310344094,0.0,0.8520009421894869,0.0
1CHO,A250T,0.2189655172413761,0.0,0.0326082472162758,0.0,-0.3828735632184581,0.0,-0.0044508291012075,0.0,0.3317241379309523,0.0,0.3044034157940994,0.0
1CHO,A250V,-0.4343678160919275,0.1171264931812872,-0.4171419178752414,0.0984966369689644,-1.0152873563219271,0.0,-0.6452954051720663,0.0,-0.8965517241380042,0.0058179543608696,-0.1574743584155683,0.0145017517198104
1CHO,A250W,-2.492183908045979,0.0011378729812272,-2.292627088776232,0.005730457641603,-3.00218390804602,0.0017126051064045,-2.725336041634653,0.0042684067060741,-2.761724137931066,0.0014629795472848,-2.516406823127329,0.0027447994083117
1CHO,A250Y,-1.9604597701149475,0.0017203022467868,-1.496990109823526,0.00457040401951,-2.39643678160924,0.00065021313211,-1.8811972653673985,4.165197673090892e-05,-2.319885057471316,0.0045514919248453,-1.6691448488379776,0.001715778682461
1CHO,E254=,-2.613491020819758e-14,0.0008127664151746,,,2.6134765647907922e-14,0.0053642583400568,-0.0982130460943611,0.0058177938579866,2.6134765647907922e-14,0.0071744765675054,-0.0058068157376322,0.0131792000873132
1CHO,E254A,0.0397701149424768,0.0,-0.6622405115172898,0.0,0.3944827586207176,0.0024382992454871,-0.487359747393686,0.0104457229669589,0.1585057471264781,0.0022582623798252,-0.7089856326787225,0.0051517800770876
1CHO,E254C,0.0583908045976794,0.0,-1.056056117028816,0.0,0.4602298850574866,0.2656301198087329,-0.8726468393407668,0.4433016742660843,0.4463218390804903,0.0031729135038705,-0.9526733621238632,0.0017048732817652
1CHO,E254D,0.7111494252873446,0.0,0.578822953562645,0.0,1.688850574712668,0.2700258106794372,0.7906897017117958,0.3887292833741385,0.6458620689655596,0.0045601918218136,0.6994828408658934,0.0080648218439207
1CHO,E254F,-0.1203448275862359,0.0035650718205009,-1.175406411678591,0.010677881094676,0.0540229885057502,0.0064223977216966,-1.0362610231088925,0.005893633398511,0.0395402298851155,0.0042169968569735,-1.2463587497249158,0.0090492868591496
1CHO,E254G,1.850114942528684,0.0,0.625093131658528,0.0,2.278275862069008,0.0053642583400567,0.769971910947719,0.0031373524720181,1.9839080459770368,0.0039417076320677,0.4957882924446264,0.0004572140975129
1CHO,E254H,0.0470114942528856,0.0,-0.4314636546003949,0.0,-0.0704597701148967,0.0644562200803239,-0.5333313908805843,0.0048647998011521,0.1352873563219068,0.0043344155482629,-0.5103634165372265,0.0062203985750406
1CHO,E254I,0.4548275862068566,0.0759123831756751,-0.423452092424391,0.0243601788185481,1.2197701149425642,0.268621107717109,0.3015004479871827,0.4682537966022471,0.7019540229885286,0.09623195542859,-0.4748872175256455,0.0707853636986317
1CHO,E254K,0.5097701149424964,0.0,0.045412924417821,0.0,0.8443678160919807,0.4526306892936795,0.3037365700994027,0.5528015358857726,0.6131034482758951,0.001697106098901,-0.0299806393252964,0.0069705214918576
1CHO,E254L,-0.5575862068965647,0.0433481178474169,-1.030377926926482,0.1971767348667924,-0.1456321839080259,0.3676115810755787,-0.4429203476029372,0.5183641341070565,-0.4908045977011212,0.0046292024288736,-0.9343032504985764,0.0052970000619179
1CHO,E254M,0.3856321839080481,0.0,-0.3162138314908212,0.0,0.9017241379310638,0.2607995572021794,0.1487070603358874,0.382745609048215,0.3901149425287886,5.551115123125783e-17,-0.4992844900613463,0.0302383293582173
1CHO,E254N,0.8391954022988165,0.0006502131321471,0.0700430388243911,0.0026648892195417,1.7833333333333712,0.26132810181858,0.9493693527412136,0.4019810883329466,0.8831034482759135,0.0114030867358218,-0.0269939754663686,0.0064848245201288
1CHO,E254P,-0.5888505747126752,0.0029259590945697,-0.7517772240891812,0.0073030869474668,-0.484827586206879,0.0,-0.6445832335258462,0.0,-0.2751724137930518,0.0017880861133399,-1.0610263870700074,0.0027684446263193
1CHO,E254Q,-0.7298850574713062,0.0,-0.4378156100922532,0.0,-0.2652873563218382,0.2697589730740544,-0.0569333443861824,0.3836794576039718,-0.662183908045921,0.0017880861133399,-0.538406823933755,0.0020442338761552
1CHO,E254R,0.7657471264367595,0.0032510656606248,-0.0864282998840354,0.005160740507001,0.7297701149425472,0.0043007556169776,-0.2264863514660424,0.0082625852174302,0.413103448275894,0.0032019283396044,-0.5367489214870732,0.0128275878530572
1CHO,E254S,0.2039080459769985,0.0,-0.0474576049008772,0.0052863052367458,0.4551724137931076,0.2736410591466328,0.1693646878754862,0.4186183627149547,0.393793103448294,0.0016255328303124,-0.0695604604808047,0.0035192608246623
1CHO,E254T,0.2773563218390555,0.0,-0.5255949393140641,0.0,1.0966666666666598,0.0852732584314333,0.2793606416846105,0.3482561674713466,0.5678160919540555,0.0032632343831179,-0.5410593989037923,0.0066151857608608
1CHO,E254V,-0.2645977011494407,0.0013004262642573,-1.1728002558966286,0.0095430127152023,-0.465402298850546,0.0041506827782329,-1.2285465371776787,0.0036186519113454,-0.3177011494252231,0.0086886212363056,-1.0684736511753703,0.0082397701933497
1CHO,E254W,1.7790804597700964,0.0,-0.142194209760701,0.0,1.7741379310345289,0.0477906652112443,0.0871044531029331,0.0348646168552187,2.5386206896552,0.0061319442153211,0.3747063614915877,0.005362413866819
1CHO,E254Y,-0.1929885057471626,0.0,-0.8279957740483721,0.0061229501135317,-0.0018390804597788,0.0013004262642573,-0.9145582840634904,0.0038220043802027,0.1497701149425676,0.1288532918802812,-0.9673001565024292,0.0816405053973401
1CHO,G267=,0.0,0.0,,,0.0,0.0,0.3637556174710857,0.0,5.226982041639516e-14,0.0009753196982022,0.0429624178262975,0.003987815097925
1CHO,G267A,-0.4688505747126119,0.0008127664151377,-0.3405146597497568,0.0004471279483269,-0.4541379310344853,0.0,0.2343580874339005,0.0,-1.3786206896551627,0.0065849129137404,-0.8166368883807363,0.0025924910633912
1CHO,G267C,1.5195402298850869,0.0078850909821327,0.5957174631144285,0.0077726760564056,1.2851724137931342,0.0,0.8841749915259124,0.0055045992966253,0.7259770114942826,1.1364313466177296,0.2464752586793477,0.3037950445510115
1CHO,G267D,1.6354022988506085,0.00366376493116,1.3705651007137083,0.0136653117842623,3.142528735632201,0.1850338387137673,3.0937281014803832,0.0979153365478827,1.8756321839080703,0.1206145360093223,1.672141512968043,0.0663119355369867
1CHO,G267E,2.527586206896579,0.0056239677345862,2.1772290674428816,0.0043708163267529,2.101609195402311,0.0141122091029631,2.2601952421904303,0.0102626878971764,1.5488505747126855,0.0009887730192104,1.859448256857977,0.0109666731979768
1CHO,G267F,1.506551724137954,0.0578783285143342,1.0395184713904682,0.7539912645317862,0.8719540229885334,0.0022757459624226,0.9352685778949515,0.0016934689851111,6.277701149425337,0.8171565663994989,4.734960008553723,0.7584141102267877
1CHO,G267H,3.08620689655174,0.0,2.288806274966097,0.0,1.5383908045977288,0.3215303938360636,1.2039987071474814,0.2406099639361321,2.643333333333393,0.0001625532830275,2.045873086395089,0.0037811955239963
1CHO,G267I,5.72528735632186,1.8444921025572023,3.4656501616090303,1.212571812123682,4.917816091954006,1.5534799091867204,3.484656725195981,1.987037014772196,1.0096551724138314,0.0,0.7863570322468871,0.0
1CHO,G267K,4.560919540229892,0.3204263327927276,4.094986617285328,0.4474526255739536,2.9762068965517536,0.0,2.183948197412437,0.0,4.146091954023031,0.1147498384865589,3.604820680116429,0.440118125740167
1CHO,G267L,5.30183908045982,1.0185588714747038,4.363880060921961,1.014479642594267,1.0479310344827542,0.0,0.0185145154221666,0.0,1.857241379310412,0.0,1.703462583647142,2.220446049250313e-16
1CHO,G267M,3.1391954022988684,0.0215755423939691,2.426620581414138,0.0174591575417801,1.667241379310357,0.0,1.0483856120557362,0.0182353514962698,2.343908045977044,0.0812810303358235,1.7270176247154592,0.0378457462515417
1CHO,G267N,1.000689655172429,0.0777879879299467,0.3682108378467907,0.010878334918503,1.9039080459769944,0.1682264703595454,1.6613185280966756,0.1425620296199885,1.658275862069007,1.7077122630017212,1.632437397496813,1.2093592529419483
1CHO,G267P,1.2762068965517317,0.0,1.1712403737495716,0.0,-0.2748275862069053,0.0,0.2941643437104788,0.0,-0.7890804597700637,0.1271194735263322,0.3517008102419917,0.0571140802460198
1CHO,G267Q,1.5503448275862397,0.0,0.7832132881984261,0.0,0.9482758620689656,1.1102230246251563e-16,0.7855853548661257,1.1102230246251563e-16,0.2437931034482867,0.1075364606475703,0.289653024027595,0.0664352547103339
1CHO,G267R,2.9763218390805126,0.3345636036121341,2.062175914933892,0.0302688466636985,4.680919540229904,2.1868299691059554,4.058922888478247,1.904119199777193,6.559770114942547,0.2005154541451614,5.733298875798446,0.0299941832664904
1CHO,G267S,0.6193103448276032,0.0,0.9273800222517976,0.0,1.2633333333333578,0.0071523444533598,1.735188678364999,0.0112303833213969,-0.7489655172413098,1.1102230246251563e-16,0.0834348516376974,0.0
1CHO,G267T,1.419885057471272,0.0038225952064928,1.1438321603638502,0.0102939460547645,1.5186206896551713,0.0,1.2842608839894536,0.0,0.6121839080460317,0.1144375112541277,0.5852506087822104,0.0796616778803986
1CHO,G267V,2.461724137931077,0.082180451659491,1.715716551203336,0.0126603507462726,0.9582758620689644,0.0,0.6457533905573647,0.0,-0.0102298850574123,0.1068083927658777,0.0767916785579389,0.090233541664939
1CHO,G267W,2.856436781609208,0.9300054906879498,1.1790325159165214,1.0741788326892,3.234712643678193,0.0001625532830275,2.405392292574259,0.0134233117437825,9.59390804597705,0.0157927855545468,7.606536054291067,0.3429249272675521
1CHO,G267Y,0.7043678160919983,0.1076253735564446,-0.1339738223487074,0.0696879603761145,-0.0393103448275975,0.0,0.6729917451776867,0.0,7.337126436781619,0.0055052551792286,5.807607769094162,0.0045418849222519
1CHO,K248=,0.0,0.0,,,0.0,0.0016255328303124,-0.0361729256299221,0.0008454239029225,0.0,0.0,0.0534020687442879,0.0
1CHO,K248A,1.527931034482694,0.0,-0.0410745347362692,0.0,1.4826436781609589,0.0046519784700804,-0.0533251997672195,0.000327248820381,1.4906896551723674,0.0,0.051717797092853,0.0
1CHO,K248C,1.914712643678124,0.0033942121977382,-0.2670725828154681,0.0137897503593546,1.2995402298851144,0.0,-0.0432540318698705,6.938893903907228e-18,1.3599999999999863,0.0,-0.0675902073853335,0.0
1CHO,K248D,2.072068965517168,0.0,0.1144252995235045,0.0,1.5978160919540831,0.0,-0.5032337735523165,0.0,1.0437931034482126,0.0,-0.4489239935257198,0.0076091842981281
1CHO,K248E,2.261839080459757,0.0047224456515333,-0.2208229894218393,0.0076418183872837,1.8965517241379573,0.0052017050570292,-0.5657199277014106,0.0040989231407986,1.6802298850574644,0.0383077772434212,-0.4613330279659917,0.0120701422402922
1CHO,K248F,0.8758620689655047,0.0,-0.0641916228028094,0.0,0.2287356321839614,0.0001625532830275,-0.0328204004630862,0.0030511716870293,1.0389655172413517,0.0,-0.1036869648414565,1.3877787807814457e-17
1CHO,K248G,3.5527586206896147,4.440892098500626e-16,-0.0401518937790036,0.0,3.414597701149464,0.0006502131321471,0.0199090613920617,0.0051160926034705,3.56103448275862,0.0,0.0846991081537704,0.0
1CHO,K248H,1.8088505747125747,0.0016255328303124,-0.0388494713832124,0.0104739894225224,1.7220689655172905,0.0027634058115422,-0.065000378446598,5.493538811950985e-05,1.68862068965515,0.0,0.0150465742536527,1.734723475976807e-18
1CHO,K248I,0.0744827586206532,0.0004876598490826,0.1292504752991956,0.0016755803399909,-0.1718390804597314,2.775557561562892e-17,-0.1240636889736708,1.3877787807814457e-17,-0.2034482758621191,0.0,0.0055031261173757,0.0
1CHO,K248L,0.0596551724137937,0.0,-0.0109179979426699,0.0,0.2121839080460035,0.0745371945251696,0.0280195900096513,0.0373369160171204,0.1596551724137812,0.0,0.0275934803249615,0.0
1CHO,K248M,0.5151724137930479,0.3730597845570524,-0.0092540612408602,0.0159793086585184,0.9591954022988798,0.0741242970623352,-0.0457750843720244,0.0431503550229959,0.7603448275861818,0.0,0.0275861071022988,0.0
1CHO,K248N,1.2512643678160622,0.0008127664151376,0.1076904279513143,0.0034752599302886,0.8967816091954178,0.0,-0.1881242465593451,0.0,0.4903448275861373,0.0,-0.0349916948936942,0.0
1CHO,K248P,6.146206896551671,8.881784197001252e-16,0.1442858654822571,0.0,5.514022988505771,0.1243532615189928,-0.147041038738472,0.0804496994093997,5.429999999999946,0.0,-0.0578599059492168,0.0
1CHO,K248Q,0.1975862068965053,0.0,-0.1967976296494051,0.0,0.2267816091954234,0.0,-0.1670078505334663,2.775557561562892e-17,0.247586206896499,0.0,-0.1226816789478013,1.3877787807814457e-17
1CHO,K248R,0.1793103448275537,0.0019506393963675,-0.006619348460092,0.0043462465439494,0.2529885057471812,0.0704782372529308,-0.0281752389619553,0.0469051273301156,0.1627586206896482,0.0,0.0156295781571107,0.0031360713017049
1CHO,K248S,1.1785057471264029,0.0001625532830275,-0.0433360827298787,0.0024714019258584,1.508160919540293,0.0,0.0124836533748764,0.0,1.1048275862068797,0.0,0.0704068334530034,0.0
1CHO,K248T,0.495632183907982,0.0056403881132803,-0.2746477334301159,0.0075264939705475,0.8252873563218727,0.0759170821080012,-0.0610760770385191,0.0361962938681133,0.6534482758620627,0.0,-0.0425004199600748,0.0
1CHO,K248V,-0.3900000000000295,0.0,-0.1779918223381424,0.0,0.0110344827586472,0.0006502131321101,-0.0038660751943032,0.0033808071470225,0.0668965517241241,0.0,0.0272486095841016,0.0
1CHO,K248W,-0.3371264367816344,0.000325106566055,-0.0609767625262808,0.00141764646658,0.3527586206896766,0.004226385358827,-0.661947471799459,0.0046374296338363,0.0799999999999899,0.0,-0.5149716282687286,0.0076092708420518
1CHO,K248Y,1.684827586206885,0.0,-0.1643285427677444,0.0,1.2108045977012138,0.0017880861133399,-0.35927361409928,0.005414942870474,1.120689655172414,0.0,-0.2250096160242594,0.0
1CHO,L253=,-1.4456028966473392e-19,0.0041474985178676,,,-2.6136500371383893e-14,0.2768604538863289,0.6310141706571303,0.4266100951018003,-5.226982041639516e-14,0.0049758300739958,-0.006620351370615,0.0124522917435143
1CHO,L253A,3.4777011494252705,0.0084292929275002,2.3660029379792333,0.0092462131231445,3.480804597701112,0.0053888313424108,3.4949676569551986,0.0083748591323594,3.3055172413792886,0.0133085381816412,2.579385816166518,0.0028725937922164
1CHO,L253C,2.9904597701149225,0.1313478809159743,2.2517922529633148,0.111755179547009,3.017126436781586,0.0258842816486077,3.153069532395205,0.0040949949766342,2.8786206896551576,0.0021318663207898,2.2403993295614755,0.0066644245689797
1CHO,L253D,4.169999999999973,0.0053642583400569,4.462599741292074,0.0094222731652589,4.260229885057428,0.0029259590945696,5.590688096649142,0.0627466600494867,4.351954022988463,0.0165285597803704,5.13658048021343,0.0129739645730292
1CHO,L253E,4.3466666666666445,0.0026008525285144,3.8176959307972655,0.0079458286524663,4.444022988505722,0.00292595909457,4.463686851449089,0.0602917039033711,4.076321839080453,0.0734037423676519,3.474560908035141,0.1312064144613596
1CHO,L253F,-0.2266666666666905,0.0008127664151746,-0.9701677999461268,0.0040855142156235,-1.1275862068965978,0.0025235055632071,-1.09391972422933,0.0095944327416918,-0.7887356321839434,0.0031645746891761,-1.2137335244797056,0.0042695826528423
1CHO,L253G,4.79724137931033,0.0032469992854724,4.2544016976611,0.0142158696964823,5.080804597701121,0.0015506594900208,5.234682854441956,0.0691362661630593,4.827356321839034,0.007379632606557,4.127210971842817,0.0081684264754072
1CHO,L253H,2.106321839080465,0.3720128038460409,1.832062068129828,0.1814875982383937,1.4486206896551537,0.2062780666274795,1.7493121331208763,0.3808772384252396,1.9982758620689385,0.0047140452079097,1.845112596859445,0.0034357482289501
1CHO,L253I,2.1904597701149444,0.0040638320757626,0.9592102088853786,0.0021531934416218,1.6911494252873265,0.2914928478155892,1.104197613496258,0.5311872776334978,1.9711494252873167,0.007777117160454,0.9894423570842168,0.0109322667283063
1CHO,L253K,4.179540229885067,0.0011721883939376,4.103903036689398,0.0041729053299695,4.449999999999965,0.0008601511233761,5.152579055321778,0.0024410721398747,4.9935632183908005,0.0072167067366995,5.049425610672862,0.0046338980849503
1CHO,L253M,1.3560919540229888,0.0028342133346949,1.181316674419629,0.0011624071193456,0.713563218390762,0.0040638320757995,0.670183940912398,0.0100520896888997,1.0487356321838843,0.0024382992454501,0.5636558880542258,0.0036664472260833
1CHO,L253N,2.401379310344808,0.0034136189436894,2.959177636858035,0.0121866373118412,2.471954022988489,0.1960424942003747,3.596953097623977,0.3393870414362233,2.323793103448235,0.0055339784446727,2.8389546531733187,0.0086644711237307
1CHO,L253P,8.276436781609208,0.0135271290757949,6.383410742428691,0.015181919649025,8.82494252873561,0.0050075910139889,7.44432618196837,0.032438498098129,8.431494252873517,0.0,6.467994407802085,0.0
1CHO,L253Q,2.190574712643651,0.0064223977216966,2.446144634452098,0.0018931692831428,2.1681609195402105,0.00101514492714,3.089881352755546,0.0708811394074458,2.237011494252846,0.0078984839276413,2.307101910261903,0.0113199982720238
1CHO,L253R,4.634022988505725,0.4158979353334295,4.108795587853533,0.3481027028475085,4.787356321839065,0.2503360141150557,5.275858806613632,0.4677025117998659,3.636436781609163,0.0690518616574481,2.975511727566603,0.0563441934157095
1CHO,L253S,4.287586206896568,0.008479300294941,4.2988749650352025,0.0100513764279942,4.491379310344807,0.0026008525285144,5.17174908555707,0.0693559957715315,4.270114942528694,0.0004876598490827,4.295576008485035,0.0024925804231419
1CHO,L253T,2.608850574712631,0.0033589975163605,2.839947951816852,0.0011146567013932,2.810459770114919,0.0027634058115422,3.725438175487609,0.0650825867467294,2.723448275862038,0.1168880183144472,2.971531339554249,0.1785372296792512
1CHO,L253V,1.778275862068966,0.0056098548698422,0.9092485565586674,0.0008008647224784,2.003448275862024,0.0005860941969509,1.898671133561864,0.070600959578788,1.8650574712643544,0.0052848569804943,0.7229077203867579,0.0027368268428907
1CHO,L253W,3.2606896551724067,0.0040897579022179,2.227228461785342,0.0139754034274817,2.368390804597677,0.3392488185192276,1.7667526986052955,0.5838958203589074,1.533218390804591,0.3213689505507941,0.3011439072692229,0.329968244275453
1CHO,L253Y,0.0565517241379527,0.1745842692312732,-0.3766887621112351,0.0069953514537354,-0.7935632183908564,0.0780276077446514,-0.5516653529368679,0.0728285443897088,-0.4518390804598008,0.0035761722267169,-0.6665491474920296,0.0028097709825406
1CHO,N263=,0.0,0.0,,,0.0,0.0,0.0017958094759384,0.0,0.0,0.0,-0.0129606327611546,0.0
1CHO,N263S,1.0972413793103506,0.0,0.0012755338009591,0.0,1.0755172413793592,0.0,0.0011895663142671,0.0,1.078620689655148,0.0,-0.0138067263209262,0.0
1CHO,N271=,0.0,0.0,,,1.0454600148553557e-13,0.1804341441648269,0.3499508347090407,0.4076526049609247,-5.2269838486431373e-14,0.0012902266850918,0.0510178859842157,0.0022645293924986
1CHO,N271A,0.1941379310345179,0.0,0.2721701813316972,0.0,-1.1713793103447263,0.0,-0.1723261155999894,2.775557561562892e-17,-0.4831034482759375,0.0031729135038706,0.4019555694854382,0.0018650851700059
1CHO,N271C,0.6882758620689459,0.0014629795472849,0.0985806176847823,0.001918919928719,-0.1162068965516419,0.0,0.0836264295450966,0.0,0.6195402298849906,0.0012695817260834,0.4593753560146947,0.0013650936808212
1CHO,N271D,0.1937931034483191,0.0,0.4212881727260631,0.0,-0.1396551724137053,0.0,0.9021090933417546,0.0,0.762988505747065,0.0013305559658426,0.9135971297707756,0.0101327829234319
1CHO,N271E,-0.2218390804597513,0.0022757459624226,0.4031288765584357,0.0059609242137519,-1.0399999999998697,0.0,0.9518380124018028,0.0,-0.3102298850575576,0.0032632343831179,0.7447549574028184,0.0023345222955354
1CHO,N271F,-0.8387356321839111,0.0034977296677758,-0.1325825732614322,0.0047922795719536,-1.2293103448274745,0.1283953836946775,0.7540757565490805,0.0955072674778255,-1.1119540229885816,0.0030885123775973,-0.3568416226327524,0.0160760152639871
1CHO,N271G,2.3339080459770187,0.0003251065660551,0.8100237748568496,0.0061073460722457,0.6593103448276766,0.0,0.3473427543381854,0.0,1.1401149425286683,0.0850153670254025,0.2519672755505749,0.0685160457140366
1CHO,N271H,-1.560689655172437,0.0,-0.5528875751386703,0.0,-1.9672413793102408,0.0009753196981652,-0.1147704921765316,0.0009165797610397,-1.867011494252971,0.0032510656606247,-0.4948451350554118,0.0030955492694701
1CHO,N271I,-0.7997701149425122,0.000325106566055,-0.2170631850557761,0.0038865815974996,-1.1744827586205937,0.0,-0.6539011325159844,0.0,0.079310344827514,0.5429647332431488,-0.0022488571509146,0.3363309600114655
1CHO,N271K,2.7529885057471293,0.5541962813826167,2.1737853359271,0.3954085122039353,1.0000000000001097,0.0,1.709969648418278,0.0,0.3917241379309448,0.0028155054514723,0.4823379834694878,0.004925029822382
1CHO,N271L,0.6703448275861931,0.0,0.65106740932559,0.0,-0.81862068965505,0.0380374682293699,0.6259318547403899,0.1506795435793308,-0.2396551724138495,0.0495216916003575,0.5109845462699673,0.0079932898403119
1CHO,N271M,-0.0418390804597477,0.0009050583763383,-0.3136734181619212,0.0077029937678696,-1.5351724137930247,2.220446049250313e-16,-0.8274653406195692,0.0,-0.9548275862069509,0.3772187893801493,-0.7236441730224633,0.2714887890045755
1CHO,N271P,4.278620689655191,0.0017582825908881,1.5221474330711506,0.0010442397764038,0.7241379310346082,0.0,0.1328212418006803,0.0,2.1994252873562425,0.0006502131321471,0.6914121605160582,0.0036525251625371
1CHO,N271Q,-0.8116091954022638,0.0013305559658426,-0.2167060529510392,0.003044009458376,-1.758620689655063,0.0,0.1777698214070353,0.0,-1.199425287356368,0.0011378729812297,-0.2246698966187904,0.0086130726126592
1CHO,N271R,0.998620689655158,0.0,0.3961602051713428,0.0,-0.0217241379309128,0.0,0.8387264899659127,0.0,1.4939080459769414,1.178758166532523,1.589348290456985,1.0136157410929127
1CHO,N271S,1.2880459770115094,0.0007085533336874,0.6647919867698655,0.0010290856603399,-0.3931034482757398,0.0,0.1360527780636191,0.0,0.1758620689654618,0.0014898254478988,0.7937711815737923,0.0007012662119987
1CHO,N271T,0.3565517241379674,0.0,0.2450813668762968,0.0,-0.9617241379309516,0.0,-0.3725324381769395,0.0,-0.3480459770115489,0.0021318663208264,0.413030223573368,0.00067987299204
1CHO,N271V,-0.9468965517241444,0.0015676070916049,-0.5823789439830699,0.0035077477589901,-0.6910344827585096,0.0,0.0317945553732591,0.0,-1.1708045977011927,0.0037174624434112,-0.356509637505857,0.0041134114390009
1CHO,N271W,-1.1990804597700908,0.0027634058115422,-0.9762700414979728,0.0012421015621912,-2.522643678160802,0.0008127664151747,-1.4844460258498542,0.0043321995322484,-0.7142528735632901,0.2566107850280855,-0.1278475305024711,0.2250949339206529
1CHO,N271Y,-0.6619540229884812,0.1832851520300782,0.1504159612642885,0.050964598901485,-1.4822988505746035,0.019833499035063,0.5353952103556713,0.0750691780993788,-1.0221839080460329,0.000860151123376,-0.1434931218143943,0.0099330836807172
1CHO,P249=,7.840471567008005e-14,0.0,,,-2.6134901173179483e-14,0.0001625532830275,0.0485893276516895,0.0022713261099014,0.0,0.0,0.0476186013749621,0.0076092028893626
1CHO,P249A,0.1937931034483976,2.775557561562892e-17,-0.3996251125401049,0.0,0.1819540229884892,2.775557561562892e-17,-0.1413274883141616,0.0,0.0755172413792495,0.0,-0.1694722936215463,0.0
1CHO,P249C,0.6777011494253871,0.0382539373194191,-0.3323841592859465,0.036140359856253,0.3571264367816059,0.0,-0.4577763155255305,0.0,0.5496551724137323,0.0,-0.2044700333898429,0.0
1CHO,P249D,-1.295862068965452,0.0,-0.8283742856987969,1.1102230246251563e-16,-1.2194252873563654,0.0,-0.7068728257337006,0.0,-1.5386206896552472,2.220446049250313e-16,-0.9199106375089726,0.0
1CHO,P249E,-1.3158620689654494,0.0,-0.6481504924245044,0.0,-1.5085057471264658,0.0008601511233759,-0.779321826075614,0.0254151292832554,-1.346321839080508,0.0003251065660921,-0.551117176989475,0.000957578034375
1CHO,P249F,-0.2806896551723362,0.005393732508809,-1.4593786570244918,0.0162931445299028,0.2903448275861624,0.0030105289318897,-0.9668557176446,0.01248250459267,-0.0728735632184186,0.2371023940207454,-0.7817373770093393,0.4846178525487254
1CHO,P249G,1.0231034482759744,0.0,0.2846807742485155,0.0,0.9243678160919444,0.0,0.2149678793160617,0.0,0.9079310344826932,1.1102230246251563e-16,0.2699007143295101,0.0
1CHO,P249H,-0.6237931034481868,0.0004876598490826,-0.0412801265354929,0.0011077062415737,-0.8642528735632714,0.0004876598490826,-0.0183098516732314,0.0014189462424598,-0.7796551724138604,1.1102230246251563e-16,-0.0127572523647672,0.0
1CHO,P249I,0.056551724138005,0.0,-0.6675875467904634,0.0,-0.1818390804597824,0.0863157932896599,-0.681982237937598,0.0109321797681006,-0.0204597701149814,0.0620155155131043,-0.5331158541368767,0.0281739564935249
1CHO,P249K,-0.4944827586206006,0.0025024759835741,-0.5842696544312213,0.0048784046550014,-0.4070114942528928,0.047831286268482,-0.075452740288985,0.0324494775305083,-0.3281609195402843,0.2187967189602518,-0.0010066318007364,0.2115693898652081
1CHO,P249L,-0.0582758620688419,0.0,-0.3031459783523101,0.0,0.0026436781609092,4.336808689942022e-19,-0.0236588251941376,0.0,-0.3586206896552382,0.0424264068711875,-0.3503501460518864,0.0419699339480788
1CHO,P249M,0.1303448275862608,0.0,-0.487339924803752,5.551115123125783e-17,-0.4859770114943126,0.0,-0.8850872652510197,0.0,-0.0140229885057814,0.0014448051827571,-0.3733125225059781,0.0022696703493805
1CHO,P249N,0.0089655172414809,0.0,0.1635494520275548,0.0,-0.0377011494252844,0.0,-0.0556270665756411,0.0,-0.2802298850575091,0.0933773465104272,-0.0336626947532802,0.1292054619011526
1CHO,P249Q,-0.3924137931033423,0.0,0.0911601570818487,0.0,-0.70735632183908,0.0,-0.1177621057376129,1.3877787807814457e-17,-0.5155172413793512,0.0,0.1215139249765782,1.3877787807814457e-17
1CHO,P249R,0.0010344827586746,0.0,-0.2923516808817206,0.0,-0.3259770114942804,0.0160927750200966,-0.3474145486218642,0.054721286687943,-0.0251724137931354,0.0,-0.03558948379601,0.0
1CHO,P249S,-0.4183908045976081,0.0035761722267169,0.0273711147454785,0.0284123448533074,-0.5111494252873697,0.0,0.0995815130133239,1.3877787807814457e-17,-0.5596551724138095,0.0,0.1453128037149421,0.0
1CHO,P249T,-0.1426436781608394,0.0008127664151377,0.0560463071701372,0.0066709362133145,-0.179425287356339,0.0,0.125583568890463,0.0,-0.2527586206897154,0.0,0.1684708844826955,0.0
1CHO,P249V,0.0882758620690734,0.0,-0.6842196734572977,0.0,-0.0873563218390794,0.0,-0.6477687856497322,0.0,0.0696551724137924,0.0,-0.3833370135533908,0.0
1CHO,P249W,-0.2974712643677076,0.6333971430399857,-1.653741642249435,0.8899755114676644,0.2342528735631935,0.0472404004708688,-1.12611315244017,0.156303038671534,-0.693793103448335,1.1102230246251563e-16,-1.5806724953499096,2.220446049250313e-16
1CHO,P249Y,-0.9848275862068162,1.1102230246251563e-16,-2.003074825032431,0.0,-0.463103448275914,0.0257080984992106,-1.4752234001399689,0.0061943231290424,-0.982873563218409,0.0022757459624226,-1.4458262262426604,0.01081084458297
1CHO,R256=,2.6135054768487247e-14,0.0048847193933202,,,2.6145752229922443e-14,0.4352019529597448,0.4440785651330243,0.5688302662108576,5.2273000742767785e-14,0.0736414813570175,-0.0055302504774354,0.0724737424660945
1CHO,R256A,1.671379310344873,0.0004876598491195,1.6841201324746702,0.0015196476331027,2.08804597701154,0.2574942518473922,2.1307948469001565,0.3916421258183304,1.745057471264422,0.013817029057674,1.855581487469988,0.0001228413944448
1CHO,R256C,1.740000000000043,0.0083331351541899,1.4742075848319776,0.0076024406317488,1.4160919540230072,0.0750480534831908,1.3841689887813289,0.0401414564583215,1.7711494252873947,0.0086977399596998,1.4898278355925,0.0025365147519523
1CHO,R256D,1.6052873563218792,0.008024602149753,1.7359454596942083,0.0051856034301595,2.103448275862064,0.2648851011140098,2.396979018933233,0.4737301128623566,1.7521839080460195,0.0850172318609691,1.923746355024592,0.0836403594733696
1CHO,R256E,2.269885057471269,0.0898160948959882,1.7034439139143387,0.010871874946706,2.169770114942549,0.3554007747064089,2.0293380781883266,0.5332614608215996,2.47793103448281,0.0332551600184953,1.7715990309600511,0.124943667111499
1CHO,R256F,0.2577011494253091,0.1915475771266381,0.0050249673439344,0.0006091763815585,0.6379310344827795,0.2551982486662953,0.4002225316260308,0.3993769946155937,0.8413793103448727,0.0004876598491196,0.28207859185339,0.002409226177804
1CHO,R256G,3.45655172413797,0.0087778772837092,1.8271093729796883,0.0002829905352584,3.710459770114989,0.3037585926357879,2.3649951575913257,0.4092128613409357,3.5464367816092524,0.0045514919248691,1.985697546274763,0.0077563411612567
1CHO,R256H,1.413908045977056,0.020875284753563,1.07576810465172,0.0120342992547242,1.275632183908067,0.0058519181891395,1.2137618289401304,0.0002535606033761,1.6725287356322545,0.0767251495908129,1.2238570149950636,0.0831979691170981
1CHO,R256I,1.1191954022988595,0.0076400043024794,1.2271937397748651,0.006929996228696,1.0449425287356726,0.1575141312574254,1.4904487852266948,0.1586763523050541,1.4303448275862545,0.0019708538160499,1.1789070338116436,0.013413397753775
1CHO,R256K,0.8944827586207333,0.0034252102128301,0.7943608762202895,0.0037398510520908,0.9104597701149744,0.0055387511738659,1.1861563083337208,0.007150851930485,1.1886206896552125,0.0864057476692563,1.0862351274217037,0.0695726078946805
1CHO,R256L,0.7493103448276391,0.0039717592053303,0.6337062388235515,0.004442745530024,0.5270114942528777,0.0024382992454501,0.7014881590162886,0.0022743898784119,0.807356321839146,0.0720688738564751,0.5970367579930778,0.0740664732461735
1CHO,R256M,0.7697701149425421,0.0078750313255185,0.3084391643242323,0.0076378663999301,0.6587356321839336,0.0153928603779152,0.5495317859079519,0.0095859206365547,0.94781609195406,0.0043099616687887,0.5541623327580076,0.0030162054050511
1CHO,R256N,1.2196551724138052,0.0074010850721805,1.673134673976855,0.0017870719982128,1.6641379310345163,0.2609838899836771,2.309202958392238,0.4601718831681948,1.4967816091954471,0.0438191915537329,1.922071280963996,0.1472295764449596
1CHO,R256P,4.586781609195426,0.0724150702313835,1.5988440899666356,0.0064201047918165,4.548620689655209,0.00520931916947,1.9525560748851063,0.0169236841747915,4.82137931034487,0.0019708538160591,1.6517184241133798,0.0122990421966358
1CHO,R256Q,1.2372413793103592,0.0062260241673195,1.064528343391017,0.0012134492567532,1.2289655172414065,0.1773476432050814,1.3582624603757776,0.1631800449232046,1.5428735632184172,0.0112983302226887,1.0622599696018014,0.0073683678025635
1CHO,R256S,1.90080459770118,0.0100586206240097,1.7544501162379236,0.0023300632456418,2.100114942528731,0.0,2.109411590072831,0.0,2.061954022988567,0.0775467758464595,1.8598405469921329,0.0872429280690991
1CHO,R256T,1.3922988505747451,0.0022757459624225,1.4111469696191543,0.01195187505988,1.4759770114942932,0.4286641954598899,1.7312769967869024,0.5439863846094244,1.5174712643678685,0.0043829140149218,1.464082066097019,0.0074789308222981
1CHO,R256V,1.0859770114942895,0.0060538823366578,1.3124874488451643,0.0027105918004722,1.2473563218391168,0.2968620402598969,1.9768085229007144,0.3979225046450491,1.3504597701149976,0.0009050583763017,1.429190752040624,0.0027922395812788
1CHO,R256W,0.1714942528736111,0.0103690648380309,-0.7665023865954402,0.0052648207135146,-0.197931034482704,0.3139931575672907,-0.510351393703062,0.4466161655149495,-0.009195402298816,0.0735942822343728,-0.7194790600631981,0.0878682929279973
1CHO,R256Y,-0.2090804597701103,0.1808653470076055,-0.0956373638340424,0.0082688183249436,0.3200000000000382,0.2670898841392569,0.3789163513813204,0.4273213874855657,1.2674712643678734,0.0419428421568209,1.872653464678238,0.1366636396812677
1CHO,T252=,0.0,0.0004876598490826,,,0.0,0.0,0.0361056390665751,0.0,0.0,0.0,0.0527830875001137,6.938893903907228e-18
1CHO,T252A,1.3849425287356558,0.006875446633909,0.7429922797087659,0.0019673106616547,1.383333333333369,0.0016255328303123,0.6968600079987309,0.0016409949610245,1.3520689655172584,0.0,0.5877374845670539,0.0
1CHO,T252C,1.5186206896551713,0.0,0.4873094416811439,0.0,1.5624137931034303,2.220446049250313e-16,0.4385841565261938,0.0,1.4889655172413736,0.0,0.4825692819628691,0.0
1CHO,T252D,1.7448275862069564,2.220446049250313e-16,1.5021015530277475,0.0,1.834137931034469,0.0,1.625834585224844,0.0,1.738275862068945,0.0,1.1710217000766,0.0
1CHO,T252E,,,,,1.5579310344827686,0.0,1.2406091022657015,0.0,1.563448275862105,2.220446049250313e-16,1.122450369599188,0.0
1CHO,T252F,1.0573563218391149,0.0133738978663732,1.1414744796834333,0.0205687505112172,0.8503448275862229,0.0031729135038705,1.1327591439604034,0.0083035686878349,1.082183908045999,0.0008127664151747,1.0118683063871332,0.0012474640226006
1CHO,T252G,2.0002298850575024,0.0016255328303124,1.3748251979386517,0.0014458255393218,2.008735632183921,0.0001625532830275,1.3905998205104726,0.0027186182084802,1.8593103448276045,0.0,1.1384440387337236,0.0
1CHO,T252H,1.6048275862069217,0.7770865943439097,1.8086723270540075,0.9184730577924796,1.0505747126436895,0.0001625532830274,1.042123272200324,8.079696214197279e-05,1.2786206896552013,0.0,0.985625742727954,1.1102230246251563e-16
1CHO,T252I,1.4217241379310508,0.0,0.5465882434976203,0.0,1.3513793103448608,0.0,0.4079071695802103,0.0,1.8621839080460056,0.1459728481621739,0.7766899525548635,0.0093278691889961
1CHO,T252K,1.7729885057471473,0.0045514919248822,1.3100466461448388,0.0022446421110329,1.6971264367816208,0.0253650843020876,1.3172283516658565,0.0311765289841193,1.621724137931026,2.220446049250313e-16,1.0997459786719823,0.0
1CHO,T252L,0.3234482758621041,0.0,-0.1463579554545755,0.0,0.4363218390804915,0.000325106566055,-0.0828778752612776,0.0002975088324073,0.792413793103449,0.0,-0.3091288359349886,0.0
1CHO,T252M,1.20862068965521,0.0,0.4591411541315242,0.0,1.2655172413793354,0.0,0.6640869010868363,0.0,1.0679310344827515,0.0,0.4749447124590758,5.551115123125783e-17
1CHO,T252N,1.2837931034482608,0.0,0.6513513461518885,0.0,1.3610344827586085,0.0020302898543158,0.681668261328045,0.0035550622329036,1.313793103448257,0.0,0.5599108914641655,0.0
1CHO,T252P,1.2448275862069405,0.0,0.8646237121451091,0.0,0.9968965517241384,0.1004579289134261,0.7269301263021323,0.0572484714517483,1.2141379310344684,0.0,0.48676804611879,0.0
1CHO,T252Q,1.221724137931076,0.0,0.8479998394777951,0.0,1.1288505747126596,0.0009887730192103,0.7838367221266113,0.0058961142403966,1.1600000000000112,0.0,0.6325689682608001,0.0
1CHO,T252R,0.891839080459798,0.0026008525284776,0.2347745629633428,0.0029725119871958,0.6958620689655012,0.0012902266850988,0.0789661078555838,0.0064505314057856,0.9216091954023284,0.0022757459624225,0.4469232802783404,0.0031125354020653
1CHO,T252S,1.0382758620689545,0.0,1.1939680869226448,0.0,1.038850574712671,0.0006502131321471,1.1601132279176374,0.0048625996635875,1.0227586206896973,0.0,0.9987953951714064,1.1102230246251563e-16
1CHO,T252V,1.4239080459770284,0.2158140178852372,0.4162451553643798,0.1946297465968223,1.3627586206896547,0.0004876598490826,0.4914275895662965,0.0220743419129623,1.6596551724138282,0.0,0.6270877567970369,0.0
1CHO,T252W,0.4541379310345114,0.0505294991209261,-0.36281161314311,0.6345225632284741,0.2372413793103538,0.0005631010903136,0.5402989929320651,0.0024804730778314,0.6486206896552019,0.0,0.2489910205779245,2.775557561562892e-17
1CHO,T252Y,0.92379310344828,0.0868034531387425,1.2085364109839247,0.1563073741694265,0.6726436781609296,0.005633356668888,0.92191461138895,0.0133465637063925,1.2404597701149591,0.0079351979743132,0.9826250901046844,0.0412297098972593
1CHO,Y255=,-7.84045860643031e-14,0.0043007556169776,,,-5.2254497025690703e-14,0.4302785401840793,0.4662207421762985,0.6138262456618385,2.6135054768487247e-14,0.0079651108685183,-0.150044113764088,0.0059168644880347
1CHO,Y255A,3.679655172413758,0.0042637326416163,2.159518129898066,0.0019426433934385,3.475977011494173,0.0032510656606249,2.7908384552457632,0.0014355510672191,3.026666666666705,0.0,1.803710982586883,0.0
1CHO,Y255C,3.29574712643673,0.1564591182209148,2.1666538988258,0.0039762094465058,3.2457471264366835,0.0,2.7093464108199234,4.440892098500626e-16,2.932873563218452,0.0,1.7470296817562267,2.220446049250313e-16
1CHO,Y255D,3.2797701149424623,0.0188197112072773,2.17552767186362,0.0030985057907748,3.732413793103368,0.0003251065660551,3.704427513827604,0.0007655109756779,2.9480459770115104,0.0,2.2917139913650724,0.0
1CHO,Y255E,3.29666666666662,0.1611986905527096,2.439019206527864,0.0061845603450487,4.211954022988454,0.0,4.22681329568812,0.0,3.01563218390811,0.0,2.4248087500402487,0.0
1CHO,Y255F,-0.2374712643678719,0.1595206851455078,-0.2456479102635507,0.0004779701966954,-0.6028735632184306,0.0,-0.1711308181283869,0.0052203598259658,-0.2879310344827189,0.001600964169789,-0.2236857365495591,0.0064938927921055
1CHO,Y255G,5.779885057471195,0.1633066784045498,3.218232296454731,0.0014223821106301,5.586091954022902,0.0,4.049995511868612,0.0,5.068390804597756,0.0,2.871551271918069,0.0
1CHO,Y255H,1.985057471264288,0.1457029738408821,1.350160875984476,0.0093561093429377,1.9898850574712263,2.220446049250313e-16,1.808566986716677,0.0,1.5070114942529116,0.0087778772836722,0.9381575550757808,0.0075217617516842
1CHO,Y255I,1.9260919540229435,0.1379954830274462,1.4419234052512293,0.0061765693435015,3.177816091953963,0.0,2.6844983974123005,4.440892098500626e-16,1.4142528735632809,0.0,0.952916736947796,1.1102230246251563e-16
1CHO,Y255K,4.701954022988445,0.0328948568605224,3.763526655215926,0.0184250896966766,4.7074712643677294,0.0,4.426773950392897,0.0,3.7095402298851,0.0028896103655058,2.9637064230913546,0.0013010435394083
1CHO,Y255L,0.490919540229828,0.151404400123625,0.3134454630748453,0.1590893729700627,2.234712643678084,0.0053642583400569,2.239157372732342,0.1170401653679786,0.3825287356322595,5.551115123125783e-17,0.4282638705014255,0.0
1CHO,Y255M,1.8288505747125985,0.019056902782562,0.7492278300570883,0.0060363405418699,2.28310344827579,0.2693531443956585,1.975182662231438,0.4136965459558155,1.2973563218390844,0.0,0.3634137725409879,0.0
1CHO,Y255N,2.6457471264367327,0.1535435151514435,2.044022939668954,0.03642907980503,2.1788505747126066,0.0,2.415831147907754,0.0,1.920459770114952,0.0,1.5102256324876338,0.0
1CHO,Y255P,13.157816091953968,0.1627669814074514,8.108777593496539,0.2612461572790711,13.142298850574631,0.0,9.12835901556101,0.0,11.762988505747174,0.0003251065660551,5.389662592025559,0.0035529859718692
1CHO,Y255Q,2.362068965517184,0.1480884496796848,1.6700104027781837,0.0310419724140964,3.251724137930952,0.2722767490775712,3.3440833231051443,0.4229864441560825,2.66218390804601,0.0,2.056943775892329,0.0
1CHO,Y255R,3.451034482758582,0.1393994631683134,2.013507624531265,0.0795461857140113,2.32367816091945,0.0,2.065655694338665,0.0,2.4943678160919824,0.0396789866857625,1.6077408408799805,0.1522716442528855
1CHO,Y255S,4.161264367816037,0.0033589975163506,3.060809645010304,0.0073707094661019,4.205517241379254,0.0724435260979999,3.85518489152048,0.0330573085946548,3.516666666666722,0.0,2.647708208459304,0.0
1CHO,Y255T,4.205517241379254,0.1558908866994954,3.0401777887114263,0.0194143997871175,4.424712643678096,0.0,3.9515661165037153,4.440892098500626e-16,3.542183908046056,0.0,2.704612201254161,0.0
1CHO,Y255V,1.8332183908045272,0.1887319220658296,1.5738334705663917,0.0025463230921922,2.5641379310344035,0.0022757459624224,2.456392391198039,0.0056173779309311,1.7877011494253,0.0,1.3852919738013136,0.0
1CHO,Y255W,1.023908045976948,0.3079298116874759,0.011859074135655,0.3352340743675416,0.9880459770114164,0.2337516209991187,0.9730496649528724,0.4100563759028186,0.6514942528736293,0.0039012787927719,-0.2132606677001269,0.0029106070747365
1VFB,D161=,2.613491020819758e-14,0.0024382992454501,,,-7.840471567008005e-14,0.0,-0.0276522392672679,0.022686505480449,0.0,0.0986055503745845,-0.0231422677174039,0.0042628033737191
1VFB,D161A,1.7258620689655289,0.0014629795472849,-0.0230135832986167,0.0007128060031118,1.2750574712642715,0.0010659331604133,-0.410984180530171,0.0216392650203881,-0.0999999999999874,0.0269058830458221,-1.8962560327612208,0.1098600152109276
1VFB,D165=,7.840471567008005e-14,0.0,,,-2.6134765647907922e-14,0.0035761722266799,-0.0168251745673251,0.0222961057836163,-2.6134837928052763e-14,0.0023945593857506,-1.2497286632564304,0.0028613505640374
1VFB,D165A,0.7849425287357571,0.0086153240006447,-0.3586552881086066,0.0004562570869516,0.6845977011494142,0.0004876598490826,-0.0493607084309462,0.0012626268307502,-0.5220689655172841,0.0310476770590005,-1.348852825262185,0.2766887936504574
1VFB,D165E,0.5135632183909177,0.0074189147416771,-0.2826945906802121,0.0155941226547714,0.4571264367815933,0.0006502131321471,0.0106717713328932,0.0005627083515628,-0.8410344827586478,0.0011378729812298,-2.3633983075044585,0.0009222726034464
1VFB,D165N,0.9595402298851832,0.0022757459624489,-0.3299082593100828,0.0038892530017935,0.3852873563218231,0.0037878751846709,-0.0211037422575137,0.0401366179989454,-0.9871264367816314,0.0022757459624226,-2.28833792229496,0.3200154475592801
1VFB,D207=,2.6134901173179483e-14,0.0001625532830275,,,0.0,0.0,-0.0011169537051579,0.0226050003413697,0.0,0.0,-0.0103269864167361,0.0
1VFB,D207A,2.0919540229885114,0.0059080907015551,1.457445489231602,0.0058301153102064,1.4704597701148778,0.0264961851341184,0.2536403183219606,0.1237445040922375,2.4821839080460326,0.0039550920768049,1.2845326748660928,0.0008798314217169
1VFB,D241=,0.0,0.0055268116230844,,,0.0,0.0,-0.0194467524287987,0.0226801581589035,7.840471567008005e-14,0.0,-0.4849832390126637,0.3044226706409758
1VFB,D241A,1.0502298850574647,0.0841732543149837,0.6316197111428226,0.0058719494856482,1.3213793103447862,0.0,-0.0139854251574172,0.0226481430720905,1.204137931034548,0.0,-0.4271793989130794,0.3044253276445663
1VFB,D342=,5.7824115865893605e-19,0.0097694387866091,,,-5.2273000742767785e-14,0.0437938576578563,-0.0159837767013748,0.022605020974615,0.0,0.0,-4.5824772941755483e-07,5.293955920339377e-23
1VFB,D342A,2.786436781609192,0.0056333566689205,0.5395361334097643,0.0015891392343351,1.7670114942528006,0.0547804563815767,-0.0479521899199389,1.958873119745889e-07,1.38344827586205,2.220446049250313e-16,4.575228778211849e-08,0.0
1VFB,E205=,-2.6136500371383893e-14,0.0902091637382535,,,5.2269811381377074e-14,0.0008601511234108,0.0556690929295069,0.031920905667866,-1.0454600148553557e-13,0.220111731317179,-0.060193776917291,0.091811144277575
1VFB,E205A,2.0619540229884623,0.084354974123626,-0.4650009650290433,0.007514577631839,0.1641379310344955,0.0764000430247578,0.0609044484128295,0.0179314910558146,0.9904597701148076,0.0218747440201695,-0.1112207276115368,0.0025943401814895
1VFB,G138=,5.226982041639516e-14,0.0012902266850988,,,-2.613489213816137e-14,0.000325106566055,0.0424777954463835,0.0217910338597243,7.840024925561313e-14,0.0903796253654594,0.0098494020938693,0.0030863246967039
1VFB,G138A,-0.9697701149424648,0.0034977296677586,-0.6115705582752871,0.0008827273479728,-0.5434482758620764,0.0016255328303123,0.2185695610268831,0.098733289466094,-0.6325287356320973,0.105736006411845,-0.0338329196483232,0.015766265882473
1VFB,G138E,-2.041494252873507,0.0003251065660551,-0.8921666267669098,0.0016772018939629,-1.5648275862069525,0.0013004262642573,0.1605441841139253,0.0017071906061049,-2.560459770114846,0.1302490069251624,-1.1673744494619418,0.0728593182756213
1VFB,G138W,-1.175632183907975,0.0013004262642573,-0.8571911043243263,0.0020224584751498,-0.997471264367855,0.2720775362974589,-0.325156807300808,0.6202532195610637,-1.2167816091953254,0.0071523444533598,-1.3619699486110577,0.0004051456126432
1VFB,H30=,-5.226953129581583e-14,0.0107285166800767,,,-5.2269811381377074e-14,0.0001625532830275,0.0054182484254381,0.0266592046493653,1.4456028966473392e-19,0.0034058695149656,0.0032697435142512,0.0061206714426459
1VFB,H30A,1.3652873563217789,0.0001625532830274,0.3392609154371744,0.0020626874938869,2.0505747126436424,0.0022582623797945,1.0875577505284986,0.0434511913956373,1.6272413793103364,0.0032632343831078,0.6180309563101795,0.0018948424833988
1VFB,I347=,-7.840473062459274e-14,0.0004876598490826,,,2.6134765647907922e-14,0.0095906436988469,-0.0147238423110347,0.0233276508022408,0.0,0.0,-0.4775360884477568,0.3044237647312005
1VFB,I347A,3.207931034482666,0.0058586873275207,1.054805562887709,0.0016041472580525,3.046091954023012,0.0020753413890982,0.0193213673451439,0.064085964453512,3.2375862068965424,0.0034136189436523,-0.2610762341936836,0.3043989112214318
1VFB,K339=,5.226982041639516e-14,0.0013004262642573,,,0.0,0.0475937025580618,-0.0308641913364817,0.0228958928022598,-2.6145752229922443e-14,0.2529329083968497,0.0233815580224274,0.000406274379537
1VFB,K339A,0.8298850574713459,0.2081601896443843,-0.1935117299647039,0.0053189064016647,0.9134482758620824,0.0500566464690629,-0.0146221486219495,0.0219481639523775,0.1987356321839128,0.0034058695149409,0.0215734670583755,0.0009157647863231
1VFB,L352=,0.0,0.0039550920768049,,,0.0,0.0,-0.0161437600319846,0.022605001057698,0.0,0.0,0.0020117404361716,0.0
1VFB,L352A,0.2586206896551463,0.0080344745366696,0.100876634535116,0.0053188355774297,2.2051724137930973,0.0,-0.0313451495335043,0.0226050010576611,2.21172413793103,0.0,0.0414108544311508,0.0
1VFB,L46=,7.228014483236696e-20,0.0040246302069018,,,-2.6134765647907922e-14,0.0029304709848156,0.0583913126917687,0.0200276669924709,0.0,0.0,-0.2248481096400881,0.3152852151552817
1VFB,L46D,4.990229885057468,0.0014077527257359,-0.0283322158075788,0.0007572508794929,4.40586206896548,0.0046887535757399,-0.0408143767681891,0.0195962026888999,5.235862068965507,0.0,-0.0136098823375128,0.0
1VFB,L46E,4.42114942528735,0.0099157502649391,-0.026736301121997,0.0011890582883212,3.335402298850552,0.0029663190575945,0.0342695669170312,0.0189131182914582,4.554942528735624,0.1227277286887175,-0.2224293181205567,0.3085924534038255
1VFB,N163=,0.0,0.0,,,0.0,0.0,-0.0473804164901845,6.938893903907228e-18,0.0,0.0,-0.0299136936127038,3.469446951953614e-18
1VFB,N163A,-0.0320689655171886,0.0,-0.4740691048174274,5.551115123125783e-17,0.4662068965516764,5.551115123125783e-17,0.0799098780908678,0.0225951101280619,0.6405747126436888,0.0013888558590226,0.6456504333455191,0.000520671101365
1VFB,N242=,0.0,0.0016255328303124,,,0.0,0.0,-0.0283625432670065,0.0226133018894553,-7.840471567008005e-14,0.0,-0.0450009906587873,6.938893903907228e-18
1VFB,N242A,1.58367816091949,0.0058519181891395,0.684527286634875,0.0024411300711975,1.4675862068965813,0.0,-0.0189880863667476,0.0226234105089,1.3562068965516432,0.0,-0.1331308121136536,0.0
1VFB,N31=,-5.2268374813498524e-14,0.038217656202445,,,2.6134765647907922e-14,0.0034136189436523,0.1688045607115861,0.0141661336832079,-2.6134901173179483e-14,0.0001625532830275,-0.2200844735690988,0.3277327210864286
1VFB,N31W,0.2312643678160332,0.0346238492856805,0.0041325911086815,0.0806445664380784,-0.0532183908045676,0.1821530486210531,-0.8781821500556309,0.1711325802350718,-0.1162068965517465,0.0006502131321101,-0.3799950102731715,0.0004453639550542
1VFB,Q344=,0.0,0.0079849905439051,,,2.6136500371383893e-14,0.1069288049228837,0.036083719753488,0.0871454873227749,0.0,0.0,-9.003426612252952e-05,0.0
1VFB,Q344A,2.177586206896571,0.0016255328303123,2.19808504462584,0.1246474100524366,0.301034482758637,0.0,0.0041068572682763,0.0736207678849128,0.3572413793103388,0.0004876598491195,-0.2668506687859133,0.3044268877500442
1VFB,R206=,2.6131874442114622e-14,0.0838303844662133,,,0.0,0.0011378729812297,0.0299440153593809,0.0241011551011378,5.2268374813498524e-14,0.0671345058919659,-0.0504632258400369,0.067000883635864
1VFB,R206A,1.3658620689655478,0.0083632044890101,0.6076229111143524,0.0018734432310891,0.6812643678160814,0.0024382992454871,0.0907032145997963,0.0223773564546589,0.0513793103448671,0.0822519612138973,-0.1544042628417639,0.0727315593694611
1VFB,R206W,0.176091954023006,0.2174979328014106,-0.5407518071497545,0.0220784418576486,0.9081609195402376,0.0096838654114093,-0.1644843577360163,0.043388441407028,-0.6863218390804079,0.0019974881835486,-0.3236854238196104,0.0014688377811771
1VFB,R206Y,-1.32850574712641,0.0842068369309582,-1.6250674767652211,0.0120098440127668,0.2409195402298855,0.0042044462432677,-0.146341009826194,0.0051383561441462,-0.8181609195401706,0.007189193458008,-0.513011471683988,0.243792994571513
1VFB,R348=,-7.838174553853605e-14,0.4345889610517499,,,-2.6135343889066576e-14,0.0487052605428451,-0.0319700964881242,0.0226044934652609,0.0,0.0004876598490826,-0.0484420472304563,0.0002721305467673
1VFB,R348A,0.6906896551723632,0.0704311693091361,0.9961764304691428,0.0398266232451417,0.467241379310325,0.0011378729811928,-0.0319660134308488,0.0226055584976681,1.05310344827584,0.0004876598491195,-0.0485757657731127,0.0001989795511469
1VFB,S135=,-5.226982041639516e-14,0.0017880861133399,,,0.0,0.0,-0.0359404288889535,0.0227538354968761,7.228014483236696e-20,0.0010659331603991,0.0222990849400717,0.0025163053593468
1VFB,S135D,1.0556321839079903,0.001697106098901,-0.0498602113136529,0.0011561755887413,0.9662068965517184,0.1716562668811546,-0.0421688739725428,0.0142312539798838,1.043448275862092,0.0001625532830645,0.0185959410531586,0.0008681055797233
1VFB,S135E,0.5357471264367099,0.0004876598490826,-0.1868331434444298,0.0025357101316637,0.7962068965517396,0.0019506393964044,-0.0502104744265679,0.001424672229917,0.5898850574712715,0.0097219910132317,0.0119992592154871,0.0034669244392985
1VFB,S135N,0.8916091954022537,0.0014898254479108,-0.0463886788379934,0.0019900992001088,0.9144827586207048,1.1102230246251563e-16,-0.0475013846169887,3.695932256172189e-14,0.8505747126437148,0.0581743203860943,-0.0012152393701294,0.0224922606374261
1VFB,S135Q,0.6766666666665818,0.0013305559658426,-0.0397957827579574,0.0016151193203907,0.6341379310344627,0.0,-0.0484104410339574,1.847802562313468e-14,0.7622988505747198,0.1182097711976684,0.023293478715114,0.0065083720012412
1VFB,S247=,-2.6136500371383893e-14,0.3376250471749161,,,7.840469448452032e-14,0.0004876598490826,-0.0142985314994086,0.0230716068258102,0.0,0.0016255328303124,-0.0293890273095628,0.0006576428747441
1VFB,S247A,-0.0355172413793329,0.325507784459024,-0.4056357039563598,0.0383066097840149,0.4700000000000978,0.0,-0.0468258504135268,0.0,-0.009195402298816,0.0008127664151377,0.022304830926986,0.0048495774008314
1VFB,S93=,7.840473062459274e-14,0.0018318824655652,,,0.0,0.0,-0.1429793854815304,3.6962597929721424e-14,5.2268374813498524e-14,0.159675652220382,-0.174987250902684,0.2729623154070514
1VFB,S93A,0.878965517241424,0.0050391517739647,-0.2909495644509672,0.0012840321759483,0.1458620689655178,0.0,-0.2650296633421162,0.0226050010576611,0.1078160919540869,0.0251264472978499,0.0231680224413756,0.0062691350709445
1VFB,T137=,7.840487518488241e-14,0.0032510656606248,,,-7.840471567008005e-14,0.0,-0.0288921420964151,0.0227426966294814,0.0,0.0968030390995599,-0.1938884505604629,0.302011308117973
1VFB,T137A,1.0847126436782275,0.0046633247758722,-0.3545334374795815,0.0036211431867454,1.0924137931033329,0.0,-0.103055830088853,0.0669552776639595,0.8421839080459769,0.0386066613821546,-0.0722840370137116,0.0107810297156192
1VFB,T341=,2.6134765647907922e-14,0.0018462503912789,,,0.0,0.0497049027260095,-0.0159839406348285,0.0226049610753063,2.6135343889066576e-14,0.0187698017162645,-4.718631254067516e-05,1.5463996480862831e-06
1VFB,T341A,1.5539080459770382,0.0006502131321101,0.2037002910882118,0.0084498757830604,1.4252873563218236,0.0018462503912789,-0.0319680341404275,0.0226050088250801,1.3003448275862188,0.0164178815861517,-4.6032819253683226e-05,1.2364782243736204e-06
1VFB,T52=,-7.840471567008005e-14,0.0,,,-2.613491020819758e-14,0.0008601511234108,0.0729088604033489,0.0211803913843792,0.0,0.0,0.0064961176434704,0.0
1VFB,T52F,-0.6056321839080988,0.0016497356430327,-0.4025111102034326,0.0016374931211354,0.1894252873563377,2.775557561562892e-17,-0.0160278577749752,0.0226050010576241,0.1331034482758508,0.0009753196981652,-0.159574046628609,0.202968445496748
1VFB,T53=,0.0,0.0,,,7.840471567008005e-14,0.0,0.0555068888809143,0.022605001057698,-7.840471567008005e-14,0.0,0.0064063363859155,0.0
1VFB,T53R,0.6859770114942876,0.3464607684531653,0.8808860010225251,0.5458118398648374,0.0741379310346113,0.0,-0.0884549313801816,0.087074547406061,-0.3745977011495315,0.0032510656606248,-0.0210891490201776,0.0002979937435334
1VFB,V343=,5.226953129581583e-14,0.0057148519056147,,,-2.6136500371383893e-14,0.0456450660759291,-0.0136091446041001,0.023278569788794,0.0,0.0227574596243739,-0.0285222175050186,0.0001691410777129
1VFB,V343A,1.4606896551724498,0.0075705166896785,-0.3951816997197245,0.0095441294677681,0.9720689655172275,0.0424264068711875,0.0028079222936438,0.000149572288442,1.0754022988506,0.0578262599317594,-0.241092303972123,0.3032763513500677
1VFB,W159=,1.4456028966473392e-19,0.0030105289318897,,,-1.4456028966473392e-19,0.0025024759835741,0.0674266520209992,0.0222539748558261,5.2268374813498524e-14,0.084485338923749,-0.1222050787360451,0.0709379849002884
1VFB,W159A,5.244252873563219,0.0068330408954934,1.73757923717641,0.0092632347716709,4.175402298850577,0.0022757459624224,0.0962955937948653,0.0222722993300435,3.741494252873608,0.0814777961108466,0.4711383008007868,0.2930371084048055
1VFB,W92=,-7.840471567008005e-14,0.0,,,-2.613491020819758e-14,0.0020753413891229,0.059408842040812,0.0525524653939454,-5.2273000742767785e-14,0.2132369481034393,-0.0521859904420282,0.0879747738845463
1VFB,W92A,4.348735632183811,0.0816017480817499,2.264559550216599,0.0011793463352383,5.177241379310336,0.0054108516303215,3.610179666049704,0.0427689265581798,2.9258620689654826,0.0148422808767794,2.914960591346788,0.0107429302458771
1VFB,Y139=,2.613491020819758e-14,0.0007085533336578,,,-2.6135054768487247e-14,0.0054691389670627,0.0281398610816372,0.0257429526300315,2.6136500371383893e-14,0.0602105786377237,-0.0218659469041002,0.0219510974487611
1VFB,Y139A,2.407011494252904,0.1153811172574638,-0.2218432402348518,0.2490908939137462,1.8610344827585985,0.0021131926793951,0.0521147377552311,0.0281695008187302,1.6933333333333562,0.0600145312037577,-0.2501752142339244,0.3008034041038195
1VFB,Y139E,4.062183908046017,0.6654125937616243,-0.7063980652058218,0.1822203014409934,1.9613793103447843,0.0025547253759383,0.1851047240539816,0.0254585556891297,3.447471264367835,0.0065607922725437,0.0189796860276219,0.0012679134379476
1VFB,Y208=,-2.6134765647907922e-14,0.0071301436410448,,,2.6134765647907922e-14,0.0030885123775973,0.0151759234478211,0.0040299517306356,2.6135343889066576e-14,0.0239770225146144,-0.2269215986268461,0.3383477258290823
1VFB,Y208A,3.8578160919539832,0.0086688310965259,2.383748232585449,0.0010594438159518,2.773793103448283,0.0031013189800439,1.8263820017030064,0.0018494823870189,4.040114942528775,0.3438058425797649,3.003814622970848,0.0687033934328349
1VFB,Y208F,1.140919540229851,0.0090228054743647,0.8584530980969792,0.0035775942811326,-0.0612643678160545,0.0074986236460979,-0.2148585718393651,0.0275086474939222,0.8859770114942886,0.0186355836560343,0.9189993379117496,0.0289282599421617
1VFB,Y246=,7.840950111415168e-14,0.1846128019474573,,,5.2268374813498524e-14,0.0433148837214742,-0.0157158871007496,0.0240854314373068,0.0,0.353520915813788,-0.0172551555541936,0.0119210940221404
1VFB,Y246A,3.827126436781693,0.1910351743490091,0.1386871223470389,0.0010402931936022,3.466896551724194,0.0131698258274807,-0.0333536646784152,0.0204953434367302,4.196321839080464,0.0789257709203287,-0.1259818301740382,0.0699061035690136
1VFB,Y32=,-5.2268374813498524e-14,0.0797295269228118,,,-5.226980234635895e-14,0.0004300755616879,0.0252936325204501,0.0415593779647518,-2.613512704863208e-14,0.0058677006979643,0.012920645150037,0.004438076211996
1VFB,Y32A,3.104597701149346,0.0217402482379404,1.236048444001865,0.0293910034794741,3.715632183907996,0.0002815505451727,2.2808763863974035,0.0002948464257499,3.308620689655156,0.0016971060989009,2.739472052359172,0.0012540755900147
1VFB,Y32W,2.800229885057428,0.0758355927326626,1.215130389638693,0.0294912461710464,-1.1351724137931531,0.0027054258151634,-0.6386934065777292,0.0285670012887436,0.7891954022988227,0.0784304008939075,-1.6858760754433562,0.7407850419049856
1VFB,Y49=,0.0,0.1437630094292945,,,2.8912057932946783e-19,0.0039717592052962,0.0460430216661075,0.0222731366127508,2.6134837928052763e-14,0.0018101167526401,0.000842401747581,0.0012030321734612
1VFB,Y49A,3.389540229885036,0.0851163201204827,0.7852081417389667,0.0233942912832959,2.3380459770115087,0.4822677581115471,0.2987145291511939,0.0322004965369982,1.6556321839080457,0.0011378729812297,0.1578575172607349,0.000706216058
1VFB,Y50=,2.616425594699952e-14,0.7319471819988574,,,2.613491020819758e-14,0.0014629795472848,0.1740115543458844,0.0196589282949281,-5.2269748136250335e-14,0.002361222825785,-0.0347761001131172,0.3582917599994095
1VFB,Y50A,1.415287356321877,0.0797474213305881,1.156482764185444,0.0111546020964537,2.905287356321846,0.0020367867984932,0.7691879435535535,0.0902443225940217,2.107586206896501,0.0016255328303123,0.9250223054906024,0.0013149206991341
1VFB,Y50K,2.4150574712644164,0.0756665889673687,2.809964182689124,0.0121281818765561,3.9903448275862208,0.4309805023670223,1.0293346185651495,0.0340089488618329,3.3573563218390614,1.0134396261293668,2.1290307196682865,0.7696140777692203
1VFB,Y50R,0.2939080459770395,0.1196019955373119,0.185138330824696,0.0167426673081552,3.549885057471266,0.3356895321813217,1.0072094181949631,0.099891225322755,3.5702298850574365,0.0587894797818335,2.0684240791031216,0.0073231605145485
2FTL,F255=,0.0,0.0016255328303124,,,2.6136500371383893e-14,0.0631558729536966,-0.3049316862713578,0.0366537196852746,2.613491020819758e-14,0.0024382992454871,-0.3196126832913042,6.93296497026308e-05
2FTL,F255A,4.860114942528725,0.001227250373804,0.0116407864664523,0.0123800598185329,5.080459770114974,0.1797839310327165,-0.1353233024771474,0.0278709526618933,4.8732183908046425,0.002763405811542,-0.3251588843385821,6.96697774664199e-05
2FTL,G234=,7.840471567008005e-14,0.0,,,0.0,0.0,-0.2246733486232454,0.0,7.840471567008005e-14,0.0,-0.6265210035073701,0.0
2FTL,G234A,2.073103448275921,0.0,-0.3270098093751052,0.0,2.354482758620681,0.0,-0.1731247149381613,0.0,2.0841379310345944,0.0,-0.658918893490691,0.0
2FTL,G258=,0.0,0.0,,,0.0,0.1103275848597017,-0.6633291930873922,0.1577446362458112,0.0,0.0,-0.7079186301488617,0.0
2FTL,G258A,1.7458620689655524,0.0004876598490826,-0.4825244374748356,0.007054655963522,1.845402298850556,0.0089492927171536,-0.7681144105468309,0.0383214129701882,1.879310344827524,0.0,-0.8665229821414461,0.0
2FTL,G259=,-2.613491020819758e-14,0.0011378729812271,,,-2.613491020819758e-14,0.0013305559658426,-0.3301134483139003,0.0530470446804307,0.0,0.0,-0.6573957164397959,0.0
2FTL,G259A,3.301724137930998,0.1464821561272095,-0.5403504709237098,0.1966251415047548,2.883563218390752,0.1750698858248069,-0.4911121207039454,0.2294358203545622,3.098965517241407,0.0,-0.6151094113751053,0.0
2FTL,I240=,-2.6127248512845352e-14,0.3255943476442225,,,0.0,0.0,-0.3059159951388226,0.0,0.0,0.0,-0.7362791106124703,0.0
2FTL,I240A,2.8579310344827102,0.0030885123775972,0.9427877387057984,0.0105231880588831,2.614827586206847,0.0,-0.2277943166519701,0.0,2.976551724137874,0.0,-0.2050060946508297,2.775557561562892e-17
2FTL,I241=,0.0,0.114213203409241,,,2.6136500371383893e-14,0.1365459188363152,-0.1569255211289136,0.1920180418417398,0.0,0.0,-0.0168530520953277,0.0
2FTL,I241A,2.0577011494252666,0.0016255328303123,0.3064634077249734,0.0132072876513495,2.4720689655172747,0.0,0.2128494866667551,0.0,2.224827586206896,0.0,0.0378462473982553,0.0
2FTL,K237=,-7.840471567008005e-14,0.0,,,-2.613491020819758e-14,0.0021503778085027,-0.6417304812191952,0.0223663649143323,0.0,0.0,-0.57389522337346,0.0
2FTL,K237A,0.8844827586205518,1.1102230246251563e-16,-0.02998156666269,0.0127548825239274,1.0095402298850462,0.0036601570869047,-0.2807400477958197,0.0067606799396376,0.8410344827586477,0.0,-0.4440665729224088,0.0
2FTL,K237D,1.8227586206895183,0.0,2.222538779331852,0.0121883668046842,1.997816091954007,0.050292840423456,2.261373757897037,0.0843063466967859,1.777586206896543,2.220446049250313e-16,1.8378774799406647,0.0
2FTL,K237E,2.191034482758505,0.0019708538160224,1.6943688749142634,0.0021306094582588,2.3013793103448204,0.0011721883939374,1.3876162350337466,0.0165741533659813,2.0910344827586216,0.0019708538160224,1.2601827887212087,0.0022996927971098
2FTL,K237F,-3.293563218390935,0.004226385358827,-4.058151872832791,0.0008506710390217,-3.135632183908095,0.0025804533701906,-4.175166418343665,0.0148154749383589,-3.3548275862069112,0.0,-4.429339833766648,0.0
2FTL,K237G,2.692068965517169,0.0,1.8517010263525635,0.0,2.8654022988505328,0.0468229645781931,1.7213549976022426,0.2528195099507234,2.6514942528736136,0.0027634058115422,1.4851417927593762,0.00480992542843
2FTL,K237H,-0.991839080459916,0.107935379932841,-1.5430344393932198,0.1334196289406627,-0.8685057471264414,0.0066289061403701,-1.5939213889448485,0.129789904706902,-0.759999999999983,0.0039012787927719,-1.639831411987834,0.0017944350263421
2FTL,K237I,0.5506896551723285,0.0,-0.8684135260078808,0.1557993196919045,1.5968965517241152,1.0910579626537982,0.0219831940108926,1.3267328064029136,0.6775862068965758,0.0035278182191453,-0.9906010255629334,0.0029071107877979
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1DAN,L453A,1.943793103448335,0.0,0.0581680089387724,4.822540436963348e-06,,,,,,,,
1DAN,L504=,-3.614007241618348e-20,0.0016497356430327,-0.1989019792430052,0.0027014493831063,0.0,0.0,0.1229618699690767,1.3859928424463485e-06,5.2273000742767785e-14,0.0580322050351347,0.0012443813653882,0.0558789431377143
1DAN,L504A,2.068275862068982,0.0008127664151008,1.594082745423293,0.0023795140006092,1.1903448275861803,0.0016893032709089,1.408463376592774,0.0455169463806741,1.6477011494252916,0.0192081312327934,1.519612149970752,0.0215933629612464
1DAN,L543=,-5.2273000742767785e-14,0.2387907727731205,0.0028594445080963,0.0014046016155115,-1.5680938896904065e-13,0.0011378729812297,-0.0019683646915502,0.0030378660934466,-1.5680943134016005e-13,0.0,-0.0001887971806898,1.2067192390979727e-05
1DAN,L543A,2.0875862068965296,0.2402544122110037,0.0032306722337595,0.0013765939290104,1.745172413792946,0.0025547253759536,-0.0032731399986935,0.0030497603556784,1.7099999999999425,0.0,-0.0091552992047393,0.0129065162772122
1DAN,M286=,1.5680512444049557e-13,0.1523189316624431,0.1258916399669994,0.0100122106993733,-1.0453674962699705e-13,0.1702046982849574,-0.2513506698491172,0.0370438148820984,0.0,0.0007085533336917,0.066154061533184,0.0152778055186711
1DAN,M286A,2.181839080459924,0.1581643443895355,1.7846084055114346,0.000917887861103,1.2895402298849588,0.1534502991816259,1.1087086196132347,0.0359672597100696,1.6510344827586243,0.0022757459624595,1.4923692510149722,0.0100972193316929
1DAN,N399=,-1.0453956855264552e-13,0.0007449127239615,-0.1996517173370454,0.001145617818761,,,,,,,,
1DAN,N399A,2.490574712643588,0.0545382616555436,0.0708178491128621,0.0922057101415391,,,,,,,,
1DAN,N478=,-5.2269748136250335e-14,0.0021318663208264,0.0041092988900429,0.0008407084648468,1.5680943134016005e-13,0.0,0.019920295543456,1.4019465553658305e-05,1.0453956855264552e-13,0.0013004262642203,0.0347125187669718,0.0131081029716759
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1DAN,N509=,-1.568094341441312e-13,0.0001625532830645,-0.0012449503510756,0.0005905107581915,0.0,0.1186631172452687,-117.38056949254342,0.0980825445687929,1.045413755562663e-13,0.0581940753251921,0.070083806604925,0.0481503043002047
1DAN,N509A,1.417241379310232,0.0013004262642942,0.0055375861079117,0.000295775073506,1.6954022988505748,0.0001625532829906,-117.1075987607088,0.0031247972625467,1.5068965517243094,0.0442144929845275,0.0722076023712675,0.0577651862457995
1DAN,N566=,5.2273000742767785e-14,0.0690903085525775,0.0033460929039026,0.0004303123325034,0.0,0.0096222756489726,-0.022877121779658,0.0267062202584754,1.0453964083279033e-13,0.0014077527257041,-0.0185517038061721,0.0135130749556771
1DAN,N566A,0.5368965517241698,0.000325106566055,0.0043960565419664,0.0004459035880605,1.1608045977011157,0.0068059178588613,-0.0031120704176211,0.0124991203252445,1.2528735632184536,0.0008127664151747,-0.0363000744064997,0.0345083662351323
1DAN,P463=,1.5680943134016005e-13,0.0,0.1048871002120873,0.000968347129239,-2.0907928166558065e-13,0.005495647396758,0.1134187038713929,0.0026469350076133,0.0,0.0,-0.0027124437384508,0.0315788813165479
1DAN,P463A,0.066321839080747,0.1422341226524665,0.3979704056407183,0.0310770931198651,1.125402298850385,0.0045601918218137,0.8187187300166379,0.0080742964671062,0.8582758620689246,0.0004876598491195,0.260609040943177,0.0022409521537057
1DAN,Q418=,0.0,0.1285796468778568,-0.0256634995118485,0.0175852472889124,,,,,,,,
1DAN,Q418A,2.079425287356362,0.1339240777734801,0.0371921833875185,0.0169475369559407,,,,,,,,
1DAN,Q450=,-1.5680943134016005e-13,0.0,0.0061365437238561,1.116364815541406e-08,,,,,,,,
1DAN,Q450A,0.1234482758619723,0.0,0.0031336098356467,0.0014278037000323,,,,,,,,
1DAN,Q481=,1.0453963086311521e-13,0.0011262021806273,0.0030540607357234,0.0021198354315502,-5.2270109536974495e-14,0.0080344745367059,-0.1106030889200835,0.0288116299720764,0.0,0.0240578858886682,-0.04056589687835,0.0527926604971348
1DAN,Q481A,1.7554022988506717,0.0014171066673834,0.1296896782866821,0.0016864355602954,1.839655172413701,0.0011721883939016,0.5993994974558299,0.0298124756894229,1.59873563218392,0.0,0.3255606760802394,0.0382171210400075
1DAN,R257=,1.5680975036976485e-13,0.0195719823150641,0.0781130996464808,0.0113061053896594,1.5680801564628885e-13,0.0259153983998472,0.2393861369699507,0.0023254380458457,-1.0453978539308e-13,0.0050783269044615,0.0652745482768463,0.0099145215926114
1DAN,R257A,1.0056321839082316,0.0034136189436155,0.7928902159126183,0.0016591713599096,1.4560919540231068,0.0153774031084021,1.185453845844379,0.0040035446918008,1.0479310344826758,0.0007085533336916,0.8393137784468173,0.014352505433201
1DAN,R502=,1.5680975036976485e-13,0.0178830776317365,0.0087825044870285,0.0596146934030694,-1.0454600148553557e-13,0.1101371369181531,0.1473534895035561,0.2826094429636765,5.7824115865893605e-19,0.0104376423767738,0.0131539207667179,0.0582370015765257
1DAN,R502A,0.18287356321864,0.0,-0.0481397552650232,0.0012830411054569,0.6625287356320936,0.1590614399633104,-0.1223988258908091,0.1563142533825672,0.4502298850575139,0.0146297954728487,-0.1422313546607193,0.0292043605978793
1DAN,R506=,-5.22696758561055e-14,0.0027151751289916,-0.1968497911972092,0.0055919999937143,1.0453964083279033e-13,0.0019775460383538,0.1643240753317294,0.0727614270053501,5.226953129581583e-14,0.015930221737143,0.080839186274998,0.0331483628946833
1DAN,R506A,2.5365517241379028,0.0573002051973226,1.135667385855016,0.0909506695282973,1.289310344827702,0.0016255328302755,0.3513703342482534,0.0418376137037715,1.887011494252864,0.019567931682322,0.6421278640447844,0.0274802823730206
1DAN,R507=,-1.0453964083279033e-13,0.0022930962463341,-0.0069569039004264,0.0020955449578531,5.2270109536974495e-14,0.0061448581170775,0.1601198214637762,0.0185236674525987,5.7824115865893605e-19,0.0521411035139079,0.0693533064950629,0.0364233885298927
1DAN,R507A,1.1966666666665164,0.0004876598491195,0.0013223941960995,0.0015252942525712,1.895057471264377,0.0089404305667737,0.2005316123415792,0.0572189641504561,1.9298850574712605,0.042059857063056,0.0263852848875417,0.0308861054572272
1DAN,R515=,0.0,0.001689303270845,0.0020530249653295,0.0020631970081424,1.5681900222830336e-13,0.2453444977556111,0.1877846950636838,0.2159261091832142,-4.625929269271485e-18,0.0581061483961845,0.023249415296583,0.029535064857271
1DAN,R515A,2.175172413793153,0.0010151449271754,0.0009077346632547,0.0012661241256187,2.1760919540231214,0.1264028167545924,0.0766933675172942,0.0584867206516431,1.5950574712643102,0.0565351344697572,0.0339607216328554,0.0322404655884724
1DAN,R563=,-3.614007241618348e-20,0.0009887730191465,0.0022308218463333,0.0012767054022069,-5.2180482157382376e-14,2.2498396824903897,0.0040664936152578,0.0361622073969739,1.5680946124918556e-13,0.0032510656606248,-0.0270667711008392,0.0376246481326569
1DAN,R563A,3.2865517241379654,0.0026008525285146,0.0033956059959219,9.507117388881296e-05,3.817126436781642,2.252663677767149,0.0193133162842864,0.0263118992273931,3.2972413793104667,0.0020367867984402,-0.0072323271056695,0.0130053486458423
1DAN,S397=,0.0,0.0,0.0046721749941784,0.0012829514990366,,,,,,,,
1DAN,S397A,-0.1468965517241141,0.0,-0.0002018959358092,0.0012830067085406,,,,,,,,
1DAN,S423=,0.0,0.0,0.0016417681348392,4.873803463993971e-06,,,,,,,,
1DAN,S423A,0.5759770114943015,0.0009050583762885,-0.315222649733448,0.0037202767639546,,,,,,,,
1DAN,S428=,-1.0453964083279033e-13,0.0017880861134138,0.0038401305975598,0.0048722711963262,,,,,,,,
1DAN,S428A,0.1141379310343711,0.1447543146159931,-0.1945398553545246,0.0274299352156264,,,,,,,,
1DAN,S530=,-5.2254497025690703e-14,0.5843606490964995,1.0795327506432832,0.7576689156278719,-1.0453964083279033e-13,0.0026160475118946,0.1064294664263212,0.0069874150169265,0.0,0.0,-0.0210474244392477,0.038288440014932
1DAN,S530A,-0.5585057471265326,0.5736505358177756,0.5667060517636605,0.7812454584037561,0.7282758620689408,0.0021318663208264,-0.2968188406034067,0.004926687744879,1.0137931034482948,0.0,-0.1070566048156251,0.0128529900975693
1DAN,S562=,0.0,0.0582755220013281,-0.0005733000474113,0.0046645096092073,5.226982041639516e-14,0.0017880861133399,5.719829548707958e-05,0.0001431976908845,1.0453964083279033e-13,0.0027151751289916,-0.0091334987836876,0.0129185745971498
1DAN,S562A,0.3179310344827674,0.0015676070915934,0.0018213009050815,0.0012788164031071,1.1162068965517518,0.0013888558589793,-0.0060165879511092,0.0002054166597439,0.3393103448277166,0.0009753196981652,-0.0362076659903636,0.0337405746509202
1DAN,T398=,-2.8912057932946783e-19,0.0039450580004019,0.000639641332092,0.0019013440725238,,,,,,,,
1DAN,T398A,1.145402298850487,0.0003251065660551,0.1302135825522029,0.0006174498625339,,,,,,,,
1DAN,T402=,0.0,0.0076641761279033,0.0054718984981901,0.000321894057349,,,,,,,,
1DAN,T402A,1.3668965517241178,0.0053642583400198,0.1290169207274222,0.0008897163926364,,,,,,,,
1DAN,T433=,5.227003725682967e-14,0.0106108826693233,0.0260051088557754,0.0190285584077076,,,,,,,,
1DAN,T433A,2.172183908046045,0.011735401395942,0.0513372334114461,0.0161138623099593,,,,,,,,
1DAN,T441=,1.4456028966473392e-19,0.002258262379764,-0.0105106115683909,0.0062562087187745,,,,,,,,
1DAN,T441A,1.448735632183939,0.0,0.3009342984527937,0.0012829903406922,,,,,,,,
1DAN,T477=,1.5680943134016005e-13,0.0,0.0119875840010044,1.1163980807303557e-08,-1.0458300891968977e-13,2.054673574678119,-0.0127628827776423,0.0361495966297224,0.0,0.0,-0.0310170151365598,0.0337320311827091
1DAN,T477A,0.7781609195404369,0.0006502131321841,0.0082223823821926,0.0007408634889885,-0.4472413793105104,0.0042263853587901,-0.0749190005401566,0.0008128928233803,0.8275862068965831,0.0,-0.0177660892758018,0.0382289282329209
1DAN,T503=,-1.5680975036976485e-13,0.0825943452584354,-0.129012528340009,0.1320911379260091,-1.0454600148553557e-13,0.1182643002291002,0.1019410052514814,0.0989744243919798,1.568085938874475e-13,0.026195298905858,0.0069795726085953,0.0552028595511569
1DAN,T503A,1.0118390804596,0.0007085533336239,-0.3944360265349729,0.0008845523363817,1.2889655172413204,0.0010151449271578,-0.0082553107534389,0.0242010176585509,1.2239080459771845,0.0,0.1188745711090308,0.0129181999503018
1DAN,T510=,-1.5680943134016005e-13,0.0,-0.2030520466397665,0.005948397721346,-1.0453674962699705e-13,0.0976872201023799,0.0908489071272255,0.0914669314691289,5.226953129581583e-14,0.0349580274158243,0.0051641584809919,0.0455375998316084
1DAN,T510A,0.9811494252872583,0.002394559385703,-0.2213489181104214,0.0027712622792112,0.5049425287355832,0.0916800516296798,0.0405057825416887,0.0799112245905607,0.3987356321839662,0.039012787927572,0.0202439686580842,0.0360827246750041
1DAN,T534=,5.2273000742767785e-14,0.2146619965370827,0.0171131914696642,0.0046831256918923,-1.045396046927179e-13,0.0004876598491195,-0.0020102028572611,0.0021389709498794,5.226982041639516e-14,0.0014171066673156,-0.0315106547349774,0.0335269151968996
1DAN,T534A,1.0572413793103816,0.2363539827864465,0.0223015070033638,0.0003869213353637,1.2855172413791238,0.001970853816068,0.0847089909766039,0.0014088250310986,0.8085057471265013,0.0009753196981652,-0.0525546621049905,0.0253561189162028
1DAN,T539=,-1.5680938896904065e-13,0.0008127664151007,0.0019680141848108,0.0006490546016092,1.0453967697286277e-13,0.0013305559658426,-0.0007818571153077,0.0003239102512689,0.0,0.0,-0.0155186747804628,0.0382645877099971
1DAN,T539A,1.846206896551556,0.0013004262642203,0.0028102982046273,0.0003392801435322,1.7700000000001437,0.0210511208614437,-0.0072655574161154,0.0107127705044472,1.6462068965516854,0.0,-0.0339545684177544,0.0253638772696341
1DAN,T564=,5.226982041639516e-14,0.0021503778085377,0.0018144941500343,0.0012830411054939,0.0,0.0,-1.6976709121499672e-06,1.3859927685213875e-06,0.0,0.0,-0.0091388665897942,0.0129243090753401
1DAN,T564A,1.1829885057472211,0.055755776079742,0.0009072470739456,0.0012830411049764,1.2303448275862796,0.0,7.671759306702725e-06,1.2639118960869784e-05,0.9793103448274796,1.1102230246251563e-16,-5.0430136102006845e-05,3.5659488774507296e-05
1DAN,T570=,-1.0453959565769981e-13,0.0021131926793893,0.0107161124832464,0.0022063399687153,1.0453964083279033e-13,0.0014629795472848,-0.0024164160446611,0.0005055648274194,1.5680943134016005e-13,0.0,-0.0796776767714325,0.0384213308805148
1DAN,T570A,0.9685057471264288,0.0013305559658426,0.1596714500846738,0.001204218630698,0.6157471264368829,0.000325106566055,-0.0931865253204674,0.0001691876703725,0.6658620689656356,0.0008446516354225,-0.0178036030612783,0.0128396788339313
1DAN,V414=,5.226982041639516e-14,0.001417106667375,0.0636908383354636,0.002205701601724,,,,,,,,
1DAN,V414A,2.421839080459789,0.1726315865793198,0.0643184341223023,0.0135632616427684,,,,,,,,
1DAN,V417=,-1.568094512795104e-13,0.0036601570868948,0.0659655303552844,0.005372269923861,,,,,,,,
1DAN,V417A,3.3356321839078347,0.1272391468929263,0.0490964282733267,0.0189224178398836,,,,,,,,
1DAN,V445=,5.226982041639516e-14,0.0037808929203417,0.0018736559604281,0.001197922151746,,,,,,,,
1DAN,V445A,1.1624137931035332,0.0050783269044615,0.0014381291225879,0.0031864914513212,,,,,,,,
1DAN,V517=,5.226982041639516e-14,0.0008127664151746,0.0037641680552334,0.0018840995354216,0.0,0.1495500805152032,0.038667587629799,0.1381405076506235,-5.227068777813315e-14,0.0445476078427873,0.0152060219823752,0.0413640671762231
1DAN,V517A,2.5308045977012577,0.0009753196982391,0.0043265474341333,0.0019435713580317,2.642873563218436,0.0178045939909348,0.0370070189475474,0.0361263447264212,2.8279310344827664,0.0001625532830644,0.0002905535645901,0.0013881632801352
1DAN,V546=,5.2254497025690703e-14,0.3848480130256916,0.0048434683880071,0.0015040258243539,1.0453964083279033e-13,0.0017880861133399,0.0050388898757617,0.0002334745114123,0.0,0.0,-0.0153155332762399,0.012906516277249
1DAN,V546A,2.26712643678168,0.2033590297141815,0.0095139290841944,0.0022937758244745,2.788735632183928,0.0067591680128617,0.0029173726912192,0.0056097350436044,2.8935632183908546,0.0021503778084677,-0.014537067645349,0.0140037433465717
1DAN,V565=,0.0,0.0,0.0025859075260253,4.95405999075096e-06,0.0,0.0032510656606248,-0.0039655502120235,0.0027976932532913,0.0,0.0,-0.0182674628597945,0.0128821232020708
1DAN,V565A,1.5265517241379776,0.0,0.002616654035163,1.116298292858552e-08,1.7404597701149749,0.00043007556166,7.424590993933039e-05,5.86765862436808e-06,0.9851724137930934,0.0,-0.0091787818155876,0.0128742802982351
1DAN,V574=,,,,,0.0,0.0043889386418546,-0.0146112470052873,0.0017598263645231,0.0,0.002113192679395,-0.3956082642077918,0.0524375780709893
1DAN,V574A,,,,,2.501609195402261,0.0016255328302755,0.8092078099008209,0.0003929928473475,3.480114942528793,0.0107543463363279,0.9569458517221548,0.0117421967774828
1DAN,W395=,0.0,0.0,0.0004130283353323,0.0018678963721288,,,,,,,,
1DAN,W395F,2.248965517241357,0.0,-0.0045517332730286,1.478413778713443e-13,,,,,,,,
1DAN,W406=,0.0,0.0,0.0155165774742857,0.0042204338936555,,,,,,,,
1DAN,W406F,1.5944827586207762,0.0,0.0117942795485624,4.965224378112526e-06,,,,,,,,
1DAN,W426=,-1.045413755562663e-13,0.0630932931552239,0.0506612786060962,0.0656597880015516,,,,,,,,
1DAN,W426A,4.494712643678035,0.1820463964881023,0.764411207824771,0.0542218132811394,,,,,,,,
1DAN,W426F,1.3398850574711776,0.120099487538942,0.2059814741812584,0.0792893724948155,,,,,,,,
1DAN,W529=,-2.0907893833489282e-13,0.0066209291144475,1.1761047221072616,0.0035717443122114,-5.226982041639516e-14,0.0067278209777772,0.0834855671333027,0.0080411357276695,5.226982041639516e-14,0.0017880861133399,-0.0002664308555523,0.0016558673001263
1DAN,W529F,0.5790804597699594,0.1733771553495015,0.9169538597059246,0.0350123537160412,1.152298850574671,0.0101410321839404,0.1903923466449575,0.009373885557531,1.3318390804598212,0.0,0.1662013868737903,0.0337109456238208
1DAN,Y432=,-1.0453964083279033e-13,0.0063354086342718,0.0363054396389977,0.0165652139856523,,,,,,,,
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1DAN,Y459=,5.227068777813315e-14,0.017242145576822,0.0664857070164701,0.0186795804636068,,,,,,,,
1DAN,Y459A,3.715632183908101,0.0115447168087487,0.1449582081091,0.002248465503471,,,,,,,,
1DAN,Y465=,1.045413755562663e-13,0.1349485988178565,0.2142929588943185,0.0218113462569075,-1.045413755562663e-13,0.0723362109489952,0.1900079804139248,0.0096848865964361,-5.2269856556467583e-14,0.0019164749425917,0.0273598082012854,0.0144405265808787
1DAN,Y465A,3.847471264367968,0.0033825147056304,2.4493055420105354,0.0029903422078083,4.058045977011371,0.1650863644548058,2.349090539672729,0.0494884111525027,3.941494252873582,0.0071060144901406,2.098033315668043,0.052009037950359
1DAN,Y527=,1.0453964083279033e-13,0.0031352141832099,0.0208161610079587,0.0037387823306777,-5.226989269654e-14,0.0057448271262351,-0.0064661812191467,0.0068569892230745,-5.226982041639516e-14,0.002685821021935,0.1196867441933721,0.0165972394141075
1DAN,Y527L,1.1836781609196712,0.1992447757025268,-0.2230186606599174,0.005475646152642,1.5878160919539537,0.1922048055514388,-0.4763191560136717,0.1423346690401045,1.2398850574712423,0.0098596304892074,-0.0902108771651387,0.015246487621499
1DAN,Y528=,1.5680049851122634e-13,0.1803652289143046,1.2484275800677,0.0226291076598743,-1.0453962276275413e-13,0.0001625532829905,0.0088185596875477,0.0029537265915863,0.0,0.0009753196981652,0.1107666437916311,0.0117895986259109
1DAN,Y528A,4.020114942528882,0.1678430934032941,0.8150708346293795,0.5505294196772126,4.112528735632027,0.0,0.0882727759825234,0.0001342796138503,4.049655172413842,0.0,0.2123237948476396,0.0128409229051783
1DAN,Y552=,-1.0453992995336965e-13,0.0063291493783371,0.0051346496655597,0.0027536557092317,-5.226982041639516e-14,0.0004300755617159,-0.011706231290588,0.0011426897034854,0.0,0.0,-0.4105631191488236,0.0370521054110917
1DAN,Y552A,3.2019540229884504,0.176533763454207,0.0168527152793061,0.006081336707877,3.6931034482757705,0.0691986481080602,-0.0438409793514699,0.0005813957591543,4.672068965517287,0.0134703620583589,-0.3770081577906093,0.0163865674880786
2J0T,C231=,-2.613491020819758e-14,0.0014629795472848,,,0.0,0.0,-0.0154064749518385,0.1210028504890134,-5.226982041639516e-14,0.0029259590945697,-0.2182048151192917,0.0012597288625938
2J0T,C231S,0.0020689655171924,0.0,0.222055530991028,5.269112641959681e-07,0.0025287356322025,0.0050391517739648,-0.0200763178097126,0.1269665042787823,-0.0017241379311505,0.0,-0.2088726013639957,2.775557561562892e-17
2J0T,M227=,2.6131874442114622e-14,0.1023490771700729,,,-5.2268374813498524e-14,0.0464979112835531,-0.0146280926723148,0.1229934484106076,0.0,0.0,-0.2588520430227335,0.0
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2J0T,S229=,0.0,0.0043647902404638,,,-5.227068777813315e-14,0.0487692358667085,0.0768317366780906,0.0031107001212526,2.613489213816137e-14,0.000325106566055,-0.3270124336558151,0.056389041334315
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2J0T,S229E,2.644022988505739,0.0008127664151376,1.718594997597032,0.0250917284722246,1.3182758620689452,0.0024382992454871,0.6495565490046565,0.125959016464781,1.7156321839080906,0.0025024759835849,0.841207965521157,0.0555572621776426
2J0T,S229R,6.049770114942558,1.5575898584868846,3.595319422808183,1.2453242595670924,2.4159770114942014,0.520504750097269,0.9516873280861432,0.4589216107717565,7.597931034482822,0.0068117390299066,6.1514033595360695,0.0437143330225463
2J0T,S229Y,3.3436781609195307,0.0294436903659577,0.6069309839916519,0.0771401750177463,1.7321839080459174,0.0163428713445345,-0.1767964534948579,0.1248550031642114,6.396436781609235,0.0169897344523327,3.826755518830056,0.0776483978143045
2J0T,T163=,0.0,0.1418356340049772,,,7.840471567008005e-14,0.0,-0.0393102533792903,0.1159028276238833,0.0,0.0004876598490826,-0.2448570525743942,0.0039153090538723
2J0T,T163A,1.3743678160919404,0.1372820941165973,0.8836816451371723,0.1196881223562379,1.2726436781609851,0.0011378729812297,0.7419155769331147,0.1203369079039695,1.0205747126436937,0.0008127664151377,0.1310477885441736,0.00084029479663
2J0T,T163L,-0.7368965517241186,0.1377758705794945,-1.2750090118398718,0.1172561121336275,-0.7248275862068488,0.0004876598490826,-1.3807179597839507,0.11760276211379,-0.8624137931034662,0.0009753196982022,-1.6921812084426122,0.0006820255255498
2J0T,T163R,2.723793103448289,0.0001625532830275,0.902910557456171,0.0081384441392447,3.612183908046021,0.00065021313211,2.025429872534383,0.1032249660103967,2.0429885057471138,0.005047011126451,0.2865181168059625,0.0139438245793483
2J0T,T163S,1.8506896551724268,0.0044901206861094,2.0301827319433445,0.0089986572809581,1.8818390804598308,0.0027634058115421,1.821974563144108,0.0036080940338434,1.709310344827597,0.0019506393963675,1.459405419847575,0.0011784097081554
2J0T,V165=,2.6136500371383893e-14,0.0981131273464154,,,-7.840471567008005e-14,0.0,-0.1074571773377143,0.109816755164224,7.840471567008005e-14,0.0,0.2796575288129259,1.0271185368489457e-07
2J0T,V165A,0.1149425287356844,0.0057448271262497,0.3303145114775371,0.0055930125657456,1.0399999999999217,0.0010151449271667,0.480016832983724,0.1113180046283861,0.9634482758621022,0.0009753196981652,0.7386109114602618,0.0017831566559433
2J0T,V165I,0.9628735632184116,0.0222697997753282,0.5740172084012202,0.1184146387944022,1.4906896551723674,0.0,0.1931213765057832,0.1093989079108628,0.9893103448276352,0.0,0.622192390387603,0.0
2J0T,V165K,0.84850574712647,0.0037245636197591,1.102851664985787,0.0077403455877517,1.1190804597700743,0.0028201940566375,1.2247217781348343,0.0053101232056478,0.9065517241379768,1.1102230246251563e-16,1.2807590942302651,0.0
2J0T,V165S,0.2681609195402656,0.0004876598491195,0.7063225022724166,0.0042636096998323,1.2517241379309938,0.0,0.866039772273474,0.1100912769549036,1.1790804597701454,0.002427438170344,1.144692710376561,0.0014387861073048
2J0T,V230=,5.226982041639516e-14,0.0011378729811928,,,0.0,0.0053888313424108,-0.0989974069594758,0.0925071015494664,-5.226982041639516e-14,0.0013004262642573,-0.2182743378338712,9.95938436867188e-05
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2J0T,V230T,0.2677011494253078,0.0017880861133399,0.7915871731829768,0.0025430743934741,0.7313793103448081,0.0037174624433765,0.2304892688642933,0.0948826673386899,0.7796551724137557,0.0018318824655963,0.2659774858051051,0.0059127192504798
1PPF,A233=,-7.840471567008005e-14,0.0,,,0.0,0.0,0.018440023914493,0.0,7.840471567008005e-14,0.0,-0.0096675999850112,0.0
1PPF,A233C,2.402758620689524,0.0,0.6047870171626308,0.0,0.6020689655172218,0.0019506393963674,0.1635903417855064,0.0007177949215426,1.7078160919540952,0.0008127664151376,1.095837051130212,0.0011058690313056
1PPF,A233D,1.6486206896550766,0.0,0.5798713395013473,0.0,1.3724137931034548,0.0009753196981652,1.0977789035944066,0.0006689089414079,2.31793103448283,0.0750996167605003,0.3637534024696885,1.304339622482686
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1PPF,A233G,1.841494252873454,0.0006502131321101,1.1658506315811323,0.0040966446872579,1.803793103448274,0.0,1.4308157460611082,2.220446049250313e-16,1.9009195402299388,0.0762374897416932,1.4178440841601774,0.0054316461438975
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1PPF,A233P,3.4641379310344216,0.0,0.1644418736483705,0.0,3.314712643678132,0.067134505891966,0.2872187804770035,0.0112734846422267,3.471379310344909,4.440892098500626e-16,0.2696766469369416,0.0
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1PPF,E237=,2.613489213816137e-14,0.000325106566055,,,2.6134693367763084e-14,0.0055909823020765,-0.329175181976368,0.0099989834890057,7.840487518488241e-14,0.0037493118230425,-0.3484955412246804,0.0041712556631454
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1PPF,E237M,-0.5616091954022427,0.0007449127239373,-1.6360064945331618,0.0090175679684948,-0.2667816091953923,0.0822640072648193,-1.344483002023399,0.1134674109368803,-0.3973563218389882,0.1116868818256583,-1.447966397022591,0.2066776291178638
1PPF,E237N,0.7981609195402776,0.0011378729811928,-0.6765126543503399,0.0068478672237921,0.6688505747126913,0.0010151449271756,-0.5668859358624087,0.0043592351415884,0.6685057471265187,0.0463276856639595,-0.5886162552565634,0.0812358057703996
1PPF,E237P,-0.1871264367815487,2.775557561562892e-17,-1.0590707714435792,0.0,-0.0433333333333017,0.0676930502737245,-0.7193194675030438,0.066401934756153,-0.061954022988452,0.0041026593787531,-0.8997176757420623,0.0094801494719517
1PPF,E237Q,-0.6757471264367446,0.0024382992454871,-0.7759383908248948,0.0093853061248617,-0.796781609195378,0.0039949763671257,-0.8583469897720385,0.0117972874732318,-0.8452873563217395,0.0015676070916049,-0.9425627584969648,0.0043473033971015
1PPF,E237R,0.6345977011494467,0.0017126051064045,-0.7822933226644563,0.007944445951694,0.4063218390804953,0.0010659331604132,-0.7864062688843557,0.0021467316000379,0.3519540229885985,0.0580868184530866,-0.8930617179356072,0.0675301784747259
1PPF,E237S,0.7266666666666802,1.1102230246251563e-16,0.1860512289433778,0.0,0.4129885057471611,0.0005631010903136,-0.1033337289254174,0.0174747325643563,0.55597701149433,0.0082053187575026,-0.059457433192008,0.0014045062291989
1PPF,E237T,0.937126436781664,0.0564059892118891,0.0609373727168573,0.095511485620749,0.6241379310344901,0.0030885123775973,-0.3048326947826212,0.0022236080078086,1.068160919540322,0.0055387511738659,-0.5673406105961476,0.0063549118323725
1PPF,E237V,-0.2256321839079897,0.0037387255097074,-1.0768196532568968,0.010029621658999,-0.444597701149392,0.0087416796974118,-1.2038926715211833,0.0645340663996425,-0.5120689655171548,0.0027345694835313,-1.2000422731755958,0.0015645785919333
1PPF,E237W,0.8414942528736317,0.0021989800539744,-1.6157264152809996,0.0014346442832866,0.1809195402299452,0.009789703149375,-1.365825149113218,0.0149040579295657,0.9044827586207584,0.056537938699182,-0.6210654491244362,0.036291928993031
1PPF,E237Y,-0.3301149425286654,0.0052017050569923,-1.1319607859657,0.074376793499814,-0.071724137931011,0.0254726751756764,-0.8913053040678527,0.0732476743272567,0.0625287356322734,0.0377386272930014,-0.8399455269726911,0.2031491128787464
1PPF,G250=,0.0,0.0,,,-5.2263748884229244e-14,0.1176885769147156,-0.0025396957321508,0.0113623642610745,2.6135054768487247e-14,0.0052017050569923,-0.995913528048622,0.0082421468107252
1PPF,G250A,0.8520689655172426,0.0,0.4649975968396606,0.0,0.9231034482758562,0.1167132572165502,0.7128123065866938,0.0013805436364718,1.2905747126436855,0.0028342133346948,-0.4931749219576625,0.008949563347213
1PPF,G250C,3.6725287356322127,0.0843178467072798,1.9036497241271475,0.2084499947989699,4.704137931034449,0.7628776243832803,2.983739823599638,0.6200134137300454,4.563563218390802,0.0,0.6063087625691869,0.011259019719076
1PPF,G250D,3.879310344827561,0.1951372780200915,2.646369489648116,0.2247639911841425,6.178390804597669,1.2813419132659296,4.900681469339015,0.8201248109818772,5.929080459770124,0.934356270864402,3.03009385190446,0.3843424036606914
1PPF,G250E,5.041724137931041,0.2176291011875654,3.837485743650977,0.0963167980439376,7.340114942528726,0.0170680947182986,6.264225127953558,0.3257217973134632,6.920459770114978,0.20254289094269,3.4238337432302406,0.185140637466914
1PPF,G250F,3.9577011494253154,0.0037387255097443,2.6136866686654727,0.0006676924806343,3.960804597701104,0.0019506393963675,3.079734975084316,0.0044157358091238,3.2582758620689893,0.0644513005405456,1.431581906626157,0.0729884362629446
1PPF,G250H,4.07942528735632,1.223980800449037,2.5861715008962727,1.24576000005285,4.874137931034428,0.0328357631723405,3.619812636491584,0.353966251465025,4.066091954023015,0.8733194305925291,1.5182828677137583,0.4062865101025127
1PPF,G250I,11.403908045977031,0.0005860941969866,7.581177817745466,0.0068873280940014,9.559310344827551,2.5816800893020413,6.700903201668989,2.219428486849682,5.364252873563256,0.0,2.8192935166336466,0.0041098227891269
1PPF,G250K,6.871724137931047,0.115663143406926,5.586650287637796,0.0497318571118308,6.859425287356285,0.0,6.056646742242092,8.881784197001252e-16,8.495862068965542,0.1108613390274105,5.593649091464999,0.2286995791247475
1PPF,G250L,6.00471264367816,0.1793042291913462,4.120703283214969,0.2099091219173275,7.237356321839044,0.0553896584998515,4.403409006722371,0.4428236116075714,4.551954022988543,0.7225493430745192,1.8197345222310284,0.3558346542464847
1PPF,G250M,4.463218390804616,1.185338539864884,3.614608685717952,1.0449276263220393,6.540804597701121,8.881784197001252e-16,4.630404214261207,0.0,5.274137931034509,1.135360989536966,2.572699960426261,0.6633544064483275
1PPF,G250N,3.0142528735632106,0.241622920309641,1.828138662137604,0.1661748489231864,5.05517241379308,1.1385231943518788,3.918922238947504,0.8413500020080394,4.410229885057487,0.001550659490054,1.1223593532319904,0.0310192641118776
1PPF,G250P,2.739885057471289,0.303405996706328,1.3247645420922227,0.1238479185488423,5.104597701149409,0.0021256600010372,3.086565598466913,0.0193177590065211,2.911494252873607,0.0019506393963675,0.2532932775814557,0.0021836417149772
1PPF,G250Q,3.872643678160921,0.3022953979086845,2.5825414244839826,0.0864840044345604,4.301954022988496,0.9457432149182138,2.786137242842931,0.5369480371023886,2.6450574712643875,0.0013004262642572,0.4853689962029139,0.0031713113180373
1PPF,G250R,4.704482758620673,0.3101842496448033,3.4924970740192176,0.2695663693372618,6.754942528735583,0.0253583121528887,5.939917694004546,0.0019320721678147,5.019655172413799,0.7631498203513355,2.374911273066536,0.2072407832515847
1PPF,G250S,2.825172413793124,0.0063395780382221,2.3697406842078395,0.0017006864613118,2.407241379310317,0.1148123400645825,1.838752829770804,0.0134153822104171,3.1098850574712955,0.1080979332158685,1.5442400044521596,0.0016447600440964
1PPF,G250T,3.770459770114956,0.0006502131321471,2.605232002201225,0.0050995296132385,3.395977011494235,0.002966319057628,2.3211972008301287,0.0044525676538233,3.535747126436778,0.0010659331603765,1.2087953727051362,0.0105732950339514
1PPF,G250V,5.800689655172428,0.0061362518689708,3.623174341719356,0.0225400018947568,4.896321839080429,0.2808920730782532,2.394082404082213,0.0147833639944843,4.232528735632169,0.0,1.1177436243861465,0.0102792639558353
1PPF,G250W,5.118160919540233,0.4297098112278869,4.631255006879891,0.358152189021719,6.8552873563218215,0.2455435540594744,4.901407389513619,0.1098874655273929,4.026206896551753,0.4839206321567409,2.03082663066642,0.0272817272343101
1PPF,G250Y,4.860229885057483,0.4316641224978792,3.179996875951971,0.265538069996089,4.919195402298827,0.0027345694835312,3.437448510447796,0.0876048362464889,4.541609195402293,0.0006502131321471,2.0285499902728192,0.0015333971805141
1PPF,K231=,0.0,0.0,,,0.0,0.0,0.0246969442422721,3.469446951953614e-18,-2.613491020819758e-14,0.0026008525285146,-0.0272448036945917,0.0043410904658507
1PPF,K231A,1.3024137931034634,0.0,0.0250208130650019,3.469446951953614e-18,1.0565517241378797,0.0,-0.0050106709030301,0.0,0.6694252873562775,0.0,0.0242191920799463,0.0
1PPF,K231C,1.4351724137931157,2.220446049250313e-16,0.0125434859581156,0.0,1.2842528735631926,0.0003251065660551,-0.0077924319794749,0.0024689056741498,0.8470114942528638,0.0,0.0237231012308006,0.0
1PPF,K231D,2.519655172413799,0.0,0.3431446638105312,0.0,2.077931034482704,0.0,0.108138188080896,1.3877787807814457e-17,1.641149425287385,2.220446049250313e-16,0.1402112006397554,0.0
1PPF,K231E,1.8455172413793413,2.220446049250313e-16,0.0443104219503954,0.0,1.555172413793101,2.220446049250313e-16,0.0141193503849465,0.0,1.1527586206896547,0.0017880861133399,0.050057768883264,0.0087429606656722
1PPF,K231F,-0.2614942528735475,0.3476250130377926,-0.5659231412715892,0.2352008804758662,0.1668965517241115,0.0,-1.1693202500454594,0.0,-0.5034482758621076,0.0105659633970492,-1.3393359374994696,0.0028898617628088
1PPF,K231G,3.2020689655172614,0.0,0.0745141234097775,0.0,2.8368965517240903,0.0,-0.0111187121449112,0.0,2.4590804597700897,0.0,0.0459776594834693,0.0
1PPF,K231H,1.102758620689687,0.0,-1.178793120330769,0.0,0.5803448275862044,0.0,-0.0371644513529645,0.0,-0.0840229885057726,1.3877787807814457e-17,-1.2301892085067014,0.0
1PPF,K231I,0.0248275862069366,3.469446951953614e-18,-0.1893717498545936,0.0,-0.063793103448257,0.0,-0.0508888156408876,0.0,-0.3860919540230059,0.0,-0.0731758524293111,0.0
1PPF,K231L,-0.410000000000027,0.0,-0.2408885644913896,0.0,-0.3344827586206991,0.0,-0.0873943746163886,0.0,-0.5431034482758778,0.0211319267940615,-0.0907207396314083,0.0079968579202003
1PPF,K231M,0.161724137931052,0.0,-0.0643347032359213,0.0,0.0589655172413962,6.938893903907228e-18,-0.0345048575510692,0.0,-0.2760919540230196,0.0,-0.0160489234652796,0.0
1PPF,K231N,1.5258620689655016,0.0,0.0122615335791626,0.0,1.306896551724125,0.0,0.0143442049915361,0.0,0.9035632183907903,0.0,0.035897271857501,0.0
1PPF,K231P,4.0837931034483015,0.0,0.039442677210555,0.0,5.346896551724089,0.0,0.0318048396314907,0.0,5.358045977011521,0.0,0.1865028592589687,0.0
1PPF,K231Q,0.1706896551724545,0.0,-0.1458620987027016,0.0,0.4472413793103536,0.0,-0.0268213348098909,0.0,-0.2636781609195513,0.0,0.1191882646770048,0.0
1PPF,K231R,0.0706896551723887,0.0,-0.2064215212716401,0.0,-0.1055172413793241,0.0,-1.0379861003501831,0.0,-1.0805747126436598,0.0,-1.4218501031590958,2.220446049250313e-16
1PPF,K231S,1.444827586206915,0.0,0.0678265568296473,0.0,1.3827586206896525,2.220446049250313e-16,0.0143246558020407,0.0,1.224597701149425,0.0,0.0770480132897664,0.0
1PPF,K231T,1.173448275862076,0.0,0.0191707279743931,0.0,1.0003448275861515,0.0,0.02964527388401,0.0,0.5721839080459584,0.0,0.0349657984432677,0.0
1PPF,K231V,-0.3989655172413536,0.0,-0.0217367439254617,0.0,-0.4951724137931548,5.551115123125783e-17,0.0457235155854779,0.0,-0.874022988505752,0.0,0.0512063184934394,0.0
1PPF,K231W,-1.06275862068964,0.0046091810702791,-0.3448367695451954,0.0096420071520996,-1.0097701149425382,0.0025547253759407,-0.2141779683514393,0.0074831963910818,-1.423333333333364,0.0,-0.2138426373931154,0.0
1PPF,K231Y,-0.5170114942528529,0.0112983302226887,-0.737748433533063,0.0073386367225384,0.8334482758620402,0.0,-0.6551120256434694,0.0,1.1387356321838995,0.0,-0.8719642338981993,1.1102230246251563e-16
1PPF,L236=,0.0,0.0,,,0.0,0.0,-0.0064444812201223,0.0,-2.613491020819758e-14,0.0006502131321101,-0.8273095812630565,0.0028111274203818
1PPF,L236A,3.5313793103448226,0.0,2.6045330026301508,0.0,3.364482758620712,4.440892098500626e-16,2.7441464306376857,0.0,3.325172413793088,0.00065021313211,1.9145885655849144,0.0021067714377845
1PPF,L236C,2.805862068965498,0.0,2.057186938043836,0.0,2.616091954023014,0.0003251065660919,2.1295458639602285,0.000143168167909,2.5998850574712287,0.0031352141832042,1.2640722165168432,0.0078869180588436
1PPF,L236D,4.754137931034495,0.0,5.259178552016614,0.0,4.725172413793095,0.0,5.62991031507342,8.881784197001252e-16,4.47689655172412,0.0011378729812298,4.467529316002426,0.0262881958103064
1PPF,L236E,5.128620689655189,0.0,4.700386573726111,0.0,5.055172413793132,0.0,4.822006465681719,0.0,4.915172413793097,0.0017880861133401,3.881761810066904,0.0409291528214203
1PPF,L236F,2.502068965517271,0.0,1.4055990787076962,0.0,2.694022988505759,0.0011378729812298,2.021611563604272,0.0072330581975649,2.864137931034444,0.0018746559115582,1.307490362963594,0.0018782645885817
1PPF,L236G,5.152413793103451,0.0,4.428865295559608,0.0,4.9617241379310775,0.0,4.629841079300107,0.0,4.96367816091951,0.0,3.851930030790958,0.0
1PPF,L236H,4.874712643678144,0.0044009631538336,4.2997160627699005,0.0119907205369809,5.190689655172452,0.0,5.054313476722427,0.0,5.051609195402254,0.0010151449271756,4.0979636359478215,0.0020731740727923
1PPF,L236I,0.5044827586206777,0.0,-0.5480386269212839,0.0,0.5003448275862145,0.0,-0.3940994274189742,0.0,0.4628735632183696,0.0006502131321471,-1.2458978056161638,0.0066701987647694
1PPF,L236K,6.892873563218399,0.0104034101139846,5.839192016462047,0.0063757151128793,7.499885057471268,0.1596273239368203,7.087861762547122,0.0084621248382605,6.89080459770113,0.1851481893727366,5.8179561410484295,0.1708849937243678
1PPF,L236M,1.8682758620689288,0.0,0.9273046290379704,0.0,1.911609195402309,0.0027634058115422,1.3496702533481164,0.0290779486837635,1.763908045977012,0.0803886385082863,0.3185714324913481,0.0063559362779147
1PPF,L236N,2.6679310344827862,0.0,3.182039980576974,0.0,2.458275862069012,0.0,3.263304192342252,0.0,2.423103448275852,0.004328315030758,2.425160366597084,0.0055764003219575
1PPF,L236P,8.961034482758649,0.0,7.217427505779049,0.0205176473168537,8.938620689655181,0.0,7.505927232328243,8.881784197001252e-16,8.89701149425285,0.0039850427180125,6.761252771740753,0.0067274638677899
1PPF,L236Q,3.284137931034444,0.0,3.143219768098318,0.0,3.223793103448332,0.0,3.3382626098967525,0.0,3.0856321839080234,0.0021131926793951,2.322812280389261,0.0005400503862442
1PPF,L236R,6.807011494252875,0.3401144958102936,5.743417836956984,0.4628861348759576,6.454712643678181,0.155757856864112,5.770707336918579,0.2444232599283816,6.421609195402266,0.3711608339322262,4.804832527052221,0.4529711730262016
1PPF,L236S,4.642068965517238,0.0,4.379037797596868,0.0,4.477241379310397,0.0,4.5604961124765735,0.0,4.450689655172388,0.0022757459624597,3.745610449596438,0.0035227818972232
1PPF,L236T,2.948965517241348,0.0,2.82813513037563,0.02347453520668,2.806551724137974,0.0,2.8729790075318964,0.0,2.7099999999999738,0.004975830074017,2.008444595557658,0.003586801413609
1PPF,L236V,1.2799999999999965,0.0,0.3821914302158865,5.551115123125783e-17,1.1375862068965443,0.0,0.3366721037439964,5.551115123125783e-17,1.0234482758620425,0.0038018012433485,-0.5600511726389602,0.0006063364123229
1PPF,L236W,1.930344827586192,0.0082902174346265,0.0599640206233932,0.0032645716414087,2.4396551724138087,0.0,1.2135458435820456,0.0,2.05367816091951,0.0023045905351611,-0.1884305319152911,0.0028272140080346
1PPF,L236Y,6.26724137931033,8.881784197001252e-16,4.922341534867789,0.0,3.2225287356321908,0.0008127664151376,2.808022815437576,0.0071403875417638,2.7550574712643474,0.5437862884871012,1.133079329143537,0.7636391136126676
1PPF,N254=,0.0,0.0,,,-7.840471567008005e-14,0.0,0.0181846772584478,0.0,-2.613491020819758e-14,0.0021503778085027,-0.9166580391885204,0.0018236927413207
1PPF,N254A,-0.0149425287356185,0.0016971060988673,0.2459488012924788,0.0020275690687131,0.1170114942527985,0.118444246391452,0.2564595098234197,0.0029998641168888,0.3340229885057151,0.001689303270877,-0.3881341735413032,0.0010576738087165
1PPF,N254C,0.6828735632183944,0.0006502131321101,0.2048883387740339,0.001131323900354,1.5413793103447586,0.0,0.3667318787313041,5.551115123125783e-17,0.9414942528735408,0.0013004262642203,-0.3609102151166887,0.0020952480182732
1PPF,N254D,-1.1627586206896796,0.0,-0.560819389335283,0.0,-0.3878160919541041,0.1150520168192788,0.2894141681617355,0.0059667157246357,-1.7622988505747512,0.000905058376325,-2.1396673693329675,0.0009725392383659
1PPF,N254E,-1.7196551724137947,0.0004876598491195,-0.3486593922942162,0.0006034253495912,-0.4710344827586941,0.1083801386739112,0.4548458855668185,0.056087917264098,0.0801149425286705,0.2454556188541158,0.1795310635813213,0.3818006058274216
1PPF,N254F,-0.811724137931049,1.1102230246251563e-16,0.5741475916250959,0.0,-1.321149425287425,0.0043647902404638,-0.1218152822605068,0.0057068263008397,-0.2447126436782023,0.0015506594900539,-0.1756796516983531,0.0033865673849047
1PPF,N254G,1.658965517241431,2.220446049250313e-16,0.6929763690090865,0.0,1.495517241379228,0.005067909812663,0.5866078121042214,0.0039801779100439,2.040919540229869,0.0014898254479108,0.0340528709570542,0.0027642065085701
1PPF,N254H,-1.5231034482758332,0.0,-0.3025445152577739,0.0,-1.9026436781610367,0.0013004262642573,-0.5122906474902273,0.0005604704103162,-0.9455172413793496,0.0015506594900268,-0.3492069995406811,0.006790404091954
1PPF,N254I,-0.5455172413792689,0.0,-0.4519589565986029,0.0,-0.5244827586207537,0.0,-0.4443920769108641,0.0,0.1524137931034246,0.2115800051042478,-1.0276083136103096,0.0803551828491278
1PPF,N254K,1.36862068965519,0.0,1.3600784346852317,0.0,0.8749425287355107,0.3581048825181485,0.6516975292756287,0.5740749570692859,2.357931034482721,0.0050705160919879,1.04798855012794,0.0082316077938887
1PPF,N254L,-0.9062068965516996,0.0,-0.3099661484684632,0.0,-0.6970114942529871,0.1144388966430034,-0.4763638969247767,0.0032415319136531,0.0565517241378743,0.0016971060988709,-0.3824214407748137,0.0016430953021841
1PPF,N254M,0.0279310344828037,3.469446951953614e-18,0.1968659754962918,0.0,-0.256896551724231,0.115254289845449,-0.129107704109643,0.0068715572314225,0.987126436781553,0.0014629795472848,0.0418220376438731,0.0060039113822193
1PPF,N254P,2.283448275862067,0.0019506393963675,0.2535076617523216,0.0005865213427549,2.705862068965432,0.1177699376935092,0.5070918546475591,0.0022604100814871,5.4495402298849855,0.0,0.7348275888923137,0.0008289454428147
1PPF,N254Q,-1.2203448275862026,0.0,-0.0313625765126493,0.0,-1.021609195402368,0.1173634703486604,-0.2046177626660382,0.0004177518313334,-0.294942528735688,0.0040605797086581,-0.1277562238239112,0.0025972240223681
1PPF,N254R,0.459655172413822,0.0,0.5429006091844713,0.0,0.4435632183907174,0.1144375112540907,0.0179238588068476,0.0135851167174699,1.685172413793058,0.0041026593787832,0.5539217491687151,0.0079205248416993
1PPF,N254S,1.0310344827586235,0.0,0.5577748096202569,0.0,1.225402298850477,0.1166327451959685,0.6263299921311137,0.0051196708342966,1.413448275862046,0.0011378729812218,-0.1272204467853765,0.0055797187827074
1PPF,N254T,1.620459770114964,0.0523421571360896,0.9731359466142444,0.0296843885680753,1.394482758620592,0.4247517285610319,0.9475764202427568,0.3104573464191111,1.5677011494252495,0.0007085533336917,0.2139634246757317,0.001723075167619
1PPF,N254V,-0.1986206896551799,0.0,-0.2645530100268592,0.0,-0.1625287356322608,0.1151732167820152,-0.0520263813989681,0.0099452479929401,0.2089655172413513,0.0019775460384176,-0.914085978417602,0.0024714432087676
1PPF,N254W,-0.6632183908045696,0.0026008525285146,0.1990136980959672,0.0001060128832373,-1.1375862068966227,0.0,0.1246062000675975,0.0,-0.201954022988539,0.0025547253759642,-0.3139737032593441,0.0021090093149306
1PPF,N254Y,-0.2636781609195513,0.0027634058115422,0.6907169554018315,0.0432445682753057,-1.816896551724192,0.0014629795472849,-0.9860943217377138,0.0066461148369187,-0.3479310344827898,0.0027054258151578,-0.2778395165374793,0.001618771581306
1PPF,P232=,7.840471567008005e-14,0.0,,,0.0,0.0,0.0057423445354021,0.0,0.0,0.0,-0.00514334528526,0.0
1PPF,P232A,0.5186206896552966,0.0,-0.0015536170161763,0.0,0.4510344827586182,0.0,-0.0474040692876479,6.938893903907228e-18,0.5065517241379486,0.0,-0.0129742918789063,0.0
1PPF,P232C,1.1341379310345567,0.0,-0.0289766010051795,3.469446951953614e-18,1.0013793103448263,0.0,-0.1451085924729168,0.0,1.0524137931034947,0.0,-0.128882232506369,0.0
1PPF,P232D,0.0337931034483392,0.0,0.0652350398716658,0.0,-0.5093103448275386,0.0,-0.6304756878693031,0.0,0.0051724137931379,0.0,0.0388176804232961,0.0
1PPF,P232E,-0.4641379310344056,0.0,0.0988950162689528,0.0,-0.5972413793103348,0.0,0.0081630741622434,0.0,-0.5565517241379423,0.0,0.0423396488437494,0.0
1PPF,P232F,-1.265517241379257,0.0,-2.375794338856771,0.0,-1.1100000000000176,0.0,-2.3271960366825453,0.0,-1.8044827586206715,0.0,-2.676437616575546,0.0
1PPF,P232G,1.1010344827586935,0.0,0.1231896016116511,0.0,1.021379310344824,0.0,0.0685500291706963,0.0,1.0506896551724223,0.0,0.0692347263528627,0.0
1PPF,P232H,-0.7555172413792426,0.0,-0.3410103682759215,0.0,-0.5059770114942318,0.0996451624982513,-0.2645453888356082,0.1052455316885958,-0.8296551724137756,0.0,-0.4506547553984123,0.0
1PPF,P232I,0.5020689655173649,0.0,-0.5828863806679128,0.0,0.3875862068965598,0.0,-0.3733441738755172,5.551115123125783e-17,0.5113793103448094,0.0,-0.7490002282035112,1.1102230246251563e-16
1PPF,P232K,-0.0010344827585178,0.0,-0.0330631267970288,0.0,0.0266666666666633,0.0091029838497643,0.0186625193157397,0.0037980278342276,0.0199999999999974,0.0,-0.0201140742098592,0.0
1PPF,P232L,0.2851724137931812,0.0,-0.1382391061992919,0.0,0.2520689655172395,0.0,-0.1091356761005186,0.0,0.3068965517241724,0.0,-0.0987802865236925,0.0
1PPF,P232M,-0.1031034482757761,1.3877787807814457e-17,-1.1241472066868043,0.0,0.2989655172413661,0.0,-0.5761693893907117,0.0,-0.3348275862068978,0.0,-1.282987467998988,0.0
1PPF,P232N,0.448620689655227,0.0,0.0805385516274515,0.0,0.4072413793103586,0.0,0.0424419063169964,0.0,0.4265517241379586,0.0,0.0414446273388703,0.0
1PPF,P232Q,-0.3931034482757398,0.0,-0.2496459826977962,0.0,-0.356551724137889,0.0,-0.2490303795476111,0.0,-0.3189655172413636,0.0,-0.1845918818789555,2.775557561562892e-17
1PPF,P232R,0.2927586206897103,0.0,-0.1339845555652385,0.0,-0.012758620689667,0.0,-0.3381144135481455,0.0,0.0013793103448733,0.0,-0.2854736935914216,0.0
1PPF,P232S,-0.141379310344699,0.0,0.0913235966355575,1.3877787807814457e-17,-0.1706896551723761,2.775557561562892e-17,0.1154730605757016,0.0,-0.1651724137931178,0.0,0.0796916345566857,0.0
1PPF,P232T,0.3665517241380446,5.551115123125783e-17,0.1601357927186121,0.0,0.3082758620689674,0.0,0.1487200505805856,0.0,0.3244827586207003,0.0,0.0825569589645463,0.0
1PPF,P232V,0.4682758620690258,0.0,-0.3013092659558299,0.0,0.3786206896551574,0.0,-0.3835670438188925,0.0,0.4658620689655561,0.0,-0.3107476964468615,0.0
1PPF,P232W,-3.378620689655095,4.440892098500626e-16,-4.004158341788768,0.0,-3.4355172413792983,0.0004876598490825,-4.410238143644952,0.0032296121227684,-3.5572413793103554,0.0,-4.104853585291996,0.0
1PPF,P232Y,-1.1282758620688649,0.0,-1.4174902428412837,0.0,-1.445172413793114,0.0,-2.093189964385927,0.0,-0.8568965517241035,0.0,-1.2844203966192411,0.0
1PPF,R239=,1.0453964083279033e-13,0.0024382992454871,,,2.6134765647907922e-14,0.0092911679898715,-0.0007065201125912,0.0105058225748105,2.6134765647907922e-14,0.0043283150307212,-0.8334883977478454,0.0011682814869992
1PPF,R239A,1.4141379310346,0.0,1.0259162158351878,0.0,1.718850574712664,0.1147007802586634,1.465178602847949,0.0072056424345327,1.829425287356368,0.0013888558590378,0.819302475809403,0.0018455361044333
1PPF,R239C,1.144827586206953,0.0,0.4753445150552988,5.551115123125783e-17,1.543333333333349,0.1207889028158812,0.9968725241102852,0.0073269865101223,1.784827586206925,0.1308990023550518,0.4044979539750638,0.0055928407456688
1PPF,R239D,1.2104597701150412,0.0014171066673453,1.0609264259341709,0.0108022371570502,1.4670114942528905,0.0055052551792342,1.4767606388572687,0.0132032401969124,1.7472413793103474,0.0037387255097075,0.8844517979530102,0.0085704676872251
1PPF,R239E,1.70344827586214,0.0029259590945698,0.9557435739594732,8.944639051432683e-06,2.151609195402357,0.1093983594801259,1.5451043129891706,0.0160132275150049,2.2642528735632266,0.0014171066673495,0.8465475061441939,0.0027087284236854
1PPF,R239F,-0.2268965517240256,0.0,-1.61032134285796,0.0,0.5301149425287709,0.071850757671644,-0.8913774100092374,0.1554577569830001,-0.0540229885057241,0.0071468007157189,-1.9514180068456923,0.0031554582326328
1PPF,R239G,3.0549425287357344,0.0013004262642572,1.1298824542506276,0.0014285251590714,3.269080459770119,0.005689364906075,1.5635455103017648,0.0055584608417811,3.475747126436785,0.0058789479781741,0.9361981972828832,0.0061086922792167
1PPF,R239H,0.7175862068965969,0.0,0.119149567087135,0.0089746419569942,1.1596551724138129,0.1209396425753774,0.6975189628771278,0.0104435036706065,0.9518390804597904,0.0018746559115116,-0.2143490736302319,0.0065368687543638
1PPF,R239I,0.2986206896552457,0.0087778772837092,-0.0689975274342774,0.0201962437056594,0.7689655172414117,0.0041665675770982,0.388547197086702,0.0023881481748625,0.8800000000000203,0.0039450580003684,-0.0721128250995792,0.0036996165360962
1PPF,R239K,1.1810344827586834,0.0,0.8678989827381915,0.0,1.3265517241379503,0.0061362518689705,1.2127044358509722,0.0049317469663273,1.2493103448276024,0.0029840816059168,0.2798949253865587,0.0057564320030353
1PPF,R239L,-0.2110344827585698,2.775557561562892e-17,-0.6728703016928005,0.0,0.3836781609195885,0.0079651108685345,-0.102537339731392,0.0160131858363477,0.4370114942529151,0.0011378729812297,-0.6239184622528939,0.0054994625060189
1PPF,R239M,0.1036781609196236,0.0023945593857632,-0.6657030926090431,0.006338640005502,0.3868965517241885,0.1110783806991249,-0.3622887597542877,0.0105391110270268,0.6134482758620938,0.0961676817591321,-0.7886840301781879,0.1554859787699552
1PPF,R239N,1.146896551724224,0.0,0.8599879148174484,0.0,1.5782758620689912,0.1224029459335363,1.250630593891831,0.0060187166983458,1.189885057471301,0.0736387902053571,0.5871632963648749,0.105941770477712
1PPF,R239P,3.765517241379388,0.0004876598491195,0.7419796301373099,0.002842276342131,4.045287356321861,0.0098837208398733,0.9045905341622072,0.0098493473542912,4.28206896551723,0.0030885123775972,0.3919086408740409,0.0019438648474542
1PPF,R239Q,0.3949425287357277,0.0027634058115422,0.1479684669138858,0.0015180397455111,0.9802298850575258,0.0028481636076763,0.7427384187573923,0.01169609603015,0.9545977011494589,0.0006502131321471,0.0078715731877769,0.0026783041505672
1PPF,R239S,1.5272413793104531,0.0,1.092750108010117,0.0,1.7102298850574866,0.0070124363414598,1.5096546113813512,0.0049501968432086,1.9258620689655297,0.0007085533336917,0.8857666842865503,0.0084350517399887
1PPF,R239T,0.863103448275916,0.0,0.6285444114075353,0.0,1.0191954022988725,0.1254276342180998,0.8841901094059533,0.0017923781621813,1.2134482758620708,0.0013888558590377,0.2442199248337434,0.0042438297912936
1PPF,R239V,0.6331034482759449,0.0,0.5284044153208454,0.0,0.863103448275916,0.0166186386868265,0.7195881136155272,0.1311816150488995,1.1040229885057753,0.1031478395959594,0.3397063311205585,0.1494518594466449
1PPF,R239W,0.3849425287357289,0.2002157641800182,0.3924977270975662,0.7985952325670881,0.9993103448276076,0.4539814617994216,0.5760941340563529,0.7448456226622298,0.7331034482758801,0.005908090701555,-1.2356442662309914,0.0059624410451756
1PPF,R239Y,0.6579310344828554,0.0014629795472848,-0.5480955854103552,0.0162531734111506,1.398045977011522,0.0842346030902892,0.5153636887814955,0.4014512013955189,0.5019540229885275,0.0004876598490826,-1.149825349351149,0.0052439604786175
1PPF,T235=,0.0,0.0,,,2.6131874442114622e-14,0.0790008955532355,-0.0861492151741668,0.1267326296758444,-2.6131874442114622e-14,0.128419871373998,-0.0812911765888463,0.0859446175262543
1PPF,T235A,1.7937931034482757,2.220446049250313e-16,0.67765530016498,0.0,1.5863218390805045,0.0607949278537438,0.5997047579359301,0.0628606340096383,1.3355172413793006,0.0347864025687449,0.3709056506699167,0.0328371642945903
1PPF,T235C,1.6195402298851005,0.0001625532830275,0.0012923607615427,0.0005404426147041,1.66804597701154,0.0798136619684472,0.2378682541428397,0.1101379013776503,1.578045977011473,0.0019506393963675,0.089948177775197,0.0033230084402973
1PPF,T235D,2.704712643678181,0.2775250640640748,1.963097141622126,0.56722606278862,2.7032183908046536,0.0001625532830275,2.330347482701088,0.0008925226490505,2.192183908045912,0.0,2.0635663781940665,0.0
1PPF,T235E,1.380574712643701,0.0227592012000526,0.2299567907517882,0.0176001221795603,1.6448275862069688,0.0,1.3179472872572018,0.0,1.8170114942528464,0.0037878751846448,1.2994169840607064,0.0019339022633394
1PPF,T235F,0.6218390804598056,0.0836069230679312,0.1484714279307934,0.0852451846639359,0.7849425287356788,0.2605053677711983,0.5469127593546258,0.3337706846707831,0.8197701149424836,0.0819268546478053,0.7063597096003341,0.0024241640443052
1PPF,T235G,2.491379310344875,0.0,1.3570207870970836,2.220446049250313e-16,2.4726436781609653,0.0928179246109094,1.603722711936926,0.1058210295345682,2.117816091953992,0.128190656825278,1.4241561180882405,0.0096594871362208
1PPF,T235H,1.258045977011513,0.9525716005884246,0.658504803524251,1.099589005929802,0.7709195402299497,0.5879552247245322,0.4136116443752423,0.6683849704449553,1.3319540229884756,0.0847772644559476,1.2588820174384072,0.003953409537802
1PPF,T235I,1.0944827586206822,0.0,-0.4672789402184207,0.0,0.7210344827586628,0.0042606328719268,-0.3173640304689915,0.0024915404233769,0.8448275862068599,0.0479747037761035,-0.49568224386108,0.0790458994398932
1PPF,T235K,2.2657471264368065,0.006014471472167,1.2156267786915238,0.0141554487086229,1.872758620689669,0.0002815505451407,0.6633751639595831,0.0008794926385115,1.673563218390772,0.0911793518149109,0.7279957830007918,0.0121300167799112
1PPF,T235L,0.7741379310344975,0.011703836378242,-1.0098377369657665,0.059438980663061,0.312413793103483,0.0024382992454871,-1.1133579757967482,0.0013726945645247,0.5737931034482454,0.1232153885378,-0.6583555977498555,0.0020367990332149
1PPF,T235M,1.7462068965517512,0.0002815505451408,-0.147823327813878,0.0029791739035687,1.3521839080460438,0.0680265582729755,0.1416617455109924,0.2232199247245359,1.3645977011493813,0.109857761242036,0.0468036253284648,0.0708341599971404
1PPF,T235N,1.687471264367847,0.0008601511234108,0.4985916276969592,0.0061760071030107,1.623218390804632,0.0842026006102649,0.7347617764815527,0.1254527013642667,1.329999999999964,0.0030885123775973,0.3264468842428806,0.0989068966987606
1PPF,T235P,1.549195402298858,0.0003251065660921,0.4726077820992711,0.0035888826210471,1.5216091954023054,0.0001625532830274,0.611914916686256,0.0013580622733057,1.2185057471264236,0.002459877535525,0.361235442917849,0.0017928957246611
1PPF,T235Q,1.2116091954023185,0.1957297459228593,0.1938246933956628,0.3102235727050073,2.12275862068969,0.0011262021805952,0.4875448346038165,0.0008588748716481,1.701609195402283,0.1457296301910012,0.7162211240357652,0.0859249486378166
1PPF,T235R,1.579885057471304,0.0133323424126601,0.2929794562028658,0.0066604425234539,1.189885057471301,0.204418945545506,0.3001183264076391,0.0490892754924754,1.4414942528735564,0.6222838403516076,0.3874972347806625,0.4721874836698399
1PPF,T235S,1.328620689655195,0.0,0.937458617241834,0.0,1.1850574712643878,0.0016255328303123,0.9695891928405956,0.0066751589506681,1.1129885057470994,0.1259564544012848,0.8900527139216159,0.1296732624907896
1PPF,T235V,1.309770114942553,0.2593547182218204,-0.2655605625408623,0.2017842997271289,0.9666666666667284,0.0018746559115212,-0.3434592845332616,0.0048876915010256,1.059080459770082,0.1069369593632108,-0.3429215502590774,0.0135862300567957
1PPF,T235W,-0.4320689655172169,0.0,-0.8215727905871187,1.1102230246251563e-16,-0.2454022988505214,0.6060561928279552,-0.2197425799233743,0.5633432631384754,0.1911494252873314,0.211736680148193,-0.2923571170454229,0.2651289897012449
1PPF,T235Y,0.4082758620690072,0.0087416796974118,0.1661079661981791,0.0831059747567726,0.8622988505747333,0.0013004262642573,0.980605572868455,0.0005925769297413,0.4781609195402131,0.005555423436136,0.5754083829296094,0.0091200252738904
1PPF,Y238=,7.840471567008005e-14,0.0,,,-2.613491020819758e-14,0.0019506393964044,0.0017698125982183,0.0038108164873691,0.0,0.0016255328303124,-0.9588799458043238,0.0295352063179478
1PPF,Y238A,3.088275862069063,0.0025804533701978,1.6504659873630354,0.0010054679346266,3.6814942528735366,0.0005860941969509,1.916877571948024,0.0022971804421546,3.293678160919485,4.440892098500626e-16,0.7958343193139439,0.0
1PPF,Y238C,3.3193103448276564,0.0,1.8731787539162537,2.220446049250313e-16,3.4840229885057385,0.0584380748113635,2.109094157240773,0.1106859205280534,3.215862068965473,0.140327552195352,0.7389962673473955,0.1238714710939428
1PPF,Y238D,3.1370114942529423,0.005689364906075,2.808759466685879,0.0003163882081686,4.298850574712602,0.027718552267051,3.3230978687547696,0.0073498311694745,4.026091954022941,0.0030454347814824,2.221634513794982,0.0134753806077173
1PPF,Y238E,4.235172413793182,0.0017582825908881,3.117978558337999,0.0078339914792739,4.46402298850572,0.001997488183577,3.549715730023792,0.005505040502729,4.1863218390804136,0.0066646846042771,2.2084847709942,0.0195404396615899
1PPF,Y238F,-0.1681609195401475,0.0022757459624595,-0.2382991136831977,0.0109573668019386,0.1068965517241191,0.0035278182191121,-0.0049297229017138,0.0061903774003007,-0.1941379310345179,0.005751722300317,-1.0112881697157972,0.0033975784651822
1PPF,Y238G,5.2177011494253405,0.0011378729812298,2.8827484660009453,0.0016938428832764,5.69540229885057,0.0397269049696011,3.1668290290255743,0.003868899809183,5.425747126436723,0.0004876598490827,2.026161012903994,0.0025343852301934
1PPF,Y238H,2.185517241379377,0.0,1.2581316815877817,0.0,2.052988505747138,0.0013305559658425,1.4189783389166868,0.0047773609496373,2.1021839080459754,0.0017880861133399,0.3494689946146589,0.0102647134649388
1PPF,Y238I,1.8524137931035247,0.0021256600010074,1.3231785635417015,0.0088638884615635,2.397011494252826,0.2571452677580255,1.481438537091396,0.1250036168763605,1.8558620689654863,0.0040638320757626,0.2624920873360428,0.0015405516611462
1PPF,Y238K,3.957471264367902,0.0045077405864547,2.823544872973025,0.0048627725502721,5.136436781609183,0.0008127664151378,4.099269259840304,0.0048375514762649,4.132988505747087,0.0029259590945696,2.1322560166100137,0.0221702252383861
1PPF,Y238L,1.7763218390805326,0.0355181713228803,1.3609215732734832,0.1927634310054858,2.6568965517241394,0.0017126051064045,1.895519296335336,0.0011293522606457,1.4509195402298385,0.0033786065417859,0.3569442270323351,0.006625540116045
1PPF,Y238M,1.716896551724231,0.0004876598490826,0.5257337948761944,0.0080617991284071,2.085172413793112,0.0002815505451408,0.8702294887256091,0.0024380344871856,1.8554022988505547,0.0085352083750344,-0.3055343367281103,0.0059778507370597
1PPF,Y238N,2.550229885057538,0.3129776360390488,1.977775674752295,0.0396787912157719,2.740689655172394,0.001689303270877,2.0800911810398124,0.0023670826231048,2.782758620689607,0.2376380560565798,1.1635720736440798,0.0200069227424294
1PPF,Y238P,12.843563218390912,0.0003251065660551,8.139597097422604,0.0020838786563686,13.357586206896556,0.0504061978334521,7.628500155684097,0.0412160493639431,12.145862068965505,0.0083632044889992,6.077166321435193,0.1249698320661503
1PPF,Y238Q,2.84344827586218,0.0,2.082353181862078,0.0,3.158505747126416,0.0020367867984562,2.3556848279749647,0.0030090902537041,3.022873563218362,0.0050391517740017,1.1691105878682313,0.0186879271359606
1PPF,Y238R,2.6267816091954885,0.2172564003807596,1.507903257779643,0.1695873938647272,2.7708045977011224,0.0018318824655652,1.678241543336802,0.0028952216863261,2.613678160919492,0.0057494248278034,0.6785190331558216,0.0174719022001092
1PPF,Y238S,3.584482758620762,0.0025804533701908,2.66334767622285,0.0087001386164765,4.264942528735609,0.000430075561688,3.1810457635480294,0.001129077869761,3.5732183908045703,0.0031645746891761,1.4568056125587396,0.0107095188572103
1PPF,Y238T,4.306321839080554,0.0047140452079097,2.9035517382157843,0.0133192893360655,4.204827586206883,0.3006541948931515,2.8139998458160256,0.1863793791695655,4.214252873563164,0.0038018012433493,1.529007876228541,0.025426126607819
1PPF,Y238V,1.7806896551724878,0.0,1.1538081700705491,0.0,3.4590804597700946,0.0142241089051335,1.7242266459638345,0.3818207153950546,1.7503448275861622,0.0996849310590456,0.0234052285839362,0.1334036679414227
1PPF,Y238W,-0.0687356321838246,0.375743979480735,-0.5303875803085886,0.0379137641077571,0.8597701149425047,0.0046802926601319,-0.1432169242979589,0.0020035909762021,0.4452873563217895,0.0235735889710293,-1.0800407189164365,0.4277540829840572
3HFM,D246=,-5.226980234635895e-14,0.0002815505451408,,,-1.0452749776845849e-13,0.1831975499763691,0.2360119000443894,0.0372331726512891,5.2263748884229244e-14,0.1835213607189655,-0.6547296949865368,0.0364990837344845
3HFM,D246A,2.6602298850573938,0.4636019632055764,1.1859344441165962,0.2923967272958528,1.929999999999915,0.2916735008542172,1.089174137278787,0.4280799247565128,2.2720689655172737,0.204254070203891,0.1618031745288815,0.0162805886857142
3HFM,D246N,1.3490804597700723,0.0052396649747052,0.1181241054643902,0.0032843667720571,0.4925287356321149,0.0084527707176541,0.7058446279499768,0.0390152219687957,0.7709195402298713,0.1355198248805769,-0.3714323744872212,0.0447075591581668
3HFM,D530=,-1.0453978539308e-13,0.0039417076320448,,,0.0,0.0141421356237291,1.0536857676107507,0.0264704917759887,5.229150445984487e-14,0.7306789600326562,0.2130729026540634,0.5441287251180744
3HFM,D530A,0.9902298850573938,0.0302038697551332,-0.9655150718938148,0.2190824120121704,3.178275862068947,0.2486636498984273,2.012215240870528,0.2914957689531659,0.3004597701149463,0.7061424629369786,-0.205915311814989,0.5584458122080533
3HFM,D530E,1.2896551724137175,0.1324087044041648,-0.5242061210992165,0.1987994520314607,3.077586206896614,0.2197990290217875,1.5896385286009975,0.3706015303984797,0.3857471264368593,0.695157893784987,-0.0530840246418607,0.6607270574979224
3HFM,D530F,3.702873563218303,0.1403653952376297,0.7270759006210081,0.0124003220198692,3.963563218390877,0.3735004721839455,1.44519485075989,0.4705966238628765,0.0072413793103565,0.7677406012858822,0.1792699478694143,1.1741696025478248
3HFM,D530G,2.379655172413738,0.0017126051064202,1.121368124772012,1.491744401377861,3.550574712643716,0.1398975711967543,2.624173670221285,0.1210680004761851,0.8229885057471097,0.1097181678853212,-0.3246361618018465,0.1962075230243893
3HFM,D530K,2.29241379310334,0.0,1.024715238109904,1.5388273472133385,5.820804597701211,0.006788424395544,2.7139627793899987,0.0137681815312108,0.9904597701149122,1.1102230246251563e-16,-0.3402436557540757,5.551115123125783e-17
3HFM,D530N,0.4240229885056255,0.0017880861133399,-0.270414167988768,0.0036655243986785,1.5944827586207762,0.0,1.1446126017992864,1.842256686428762e-14,-0.9133333333333232,0.127540532364998,-0.6829648587977474,0.2005596374907827
3HFM,D530Q,0.5779310344826303,0.1363068162527058,0.5097445482270219,1.290009977161563,2.9879310344827457,0.4454620797849773,1.8308169650682675,0.5168965951689762,-1.1934482758620473,0.1171440885484507,-1.228622107455417,0.2097740621521887
3HFM,D530R,1.100114942528621,0.0343979800738456,-0.939542704311642,0.1471708340447273,4.297356321839101,0.4192249169379844,2.629459207320368,0.2540137372142125,0.3157471264368159,0.704021871920355,0.4111589274635275,0.5422671301939813
3HFM,D530S,0.9021839080459432,0.1486654420535947,-0.3101076197324947,0.1784737030791225,2.9629885057471026,0.0052017050570291,2.8264295750930475,0.0001092273842865,-0.685057471264372,0.0,-0.1319436455635476,0.0
3HFM,G531=,1.0454600148553557e-13,0.3418270990178073,,,-1.0453964083279033e-13,0.0110810797746883,0.4673788418915853,0.0020913230307605,1.0454600148553557e-13,0.1282177596753323,-0.7904720145689815,0.2034611519941552
3HFM,G531V,2.754022988505856,0.2815053526580208,0.597398526864886,1.4159623954508995,0.2457471264366678,0.0050391517739516,0.5633475097292099,0.0054683358907231,2.966896551724231,0.0049090014951882,-0.9448896886595678,0.0393152694820923
3HFM,H444=,-1.045396046927179e-13,0.0004876598491195,,,0.0,0.0,0.2957906265074446,1.8474763863539243e-14,-1.5680943134016005e-13,0.0,0.1715584467851892,0.021285856337038
3HFM,H444A,0.9374712643676536,0.0022757459624595,0.9115849206778124,1.549572247878919,0.8385057471264975,0.0008127664151007,0.2327570701692073,0.0003940537579477,0.9082758620688136,0.0,0.1362297256494865,0.0
3HFM,I527=,-1.0453962276275413e-13,0.0001625532829905,,,1.0453964083279033e-13,0.0021131926793893,0.5575136678898365,0.006287881603784,5.226953129581583e-14,0.0135524991735402,-0.1457774276510442,0.0299988459786945
3HFM,I527A,3.515402298850504,0.0008601511233759,-0.1102826930707448,0.0764193175455402,2.8873563218392246,0.0036745672099395,0.3831739760675317,0.0018944054964379,2.831379310344858,0.0002815505451408,0.9305735996073556,1.5801222298517392
3HFM,K525=,-1.568094341441312e-13,0.0001625532830645,,,-1.567634910770721e-13,0.7727783075312138,0.4399614506629123,0.0308614166628557,-1.045413755562663e-13,0.1255697544984766,-0.576381804850052,0.2015292751643313
3HFM,K525A,1.5134482758620071,0.0222947027781139,0.9580922795808436,0.0245489953141647,1.387816091953874,0.1149888412446205,1.1340066518612957,0.2392166822890245,1.0116091954021864,0.0902188293980692,-0.1559553780537592,0.0947909360945836
3HFM,K525M,0.1726436781608095,0.4462109825888881,2.4960482436725364,1.6061932018956868,0.0621839080458394,0.191274245434637,0.5696667559110816,0.2187197158619583,-0.096551724138,0.6231613833172001,-0.1890645790733507,0.5196341961278352
3HFM,K525R,-0.0262068965517839,0.0253431985297348,0.4681363150351398,0.0218325023514245,0.7311494252872376,0.7438438231516453,1.3439226620707476,0.6746131151130168,1.0336781609194288,0.6292061321365219,0.2544181144923181,0.4936770269558502
3HFM,K526=,5.2254497025690703e-14,0.4697793254414402,,,-5.2254497025690703e-14,0.7254439417833047,0.9746764878293536,0.0827194510731295,-5.227068777813315e-14,0.0131938803239203,-0.904036435505422,0.0321865101609516
3HFM,K526A,1.4458620689654855,0.2435048179810302,3.145710367552025,1.2916121394465312,3.806091954023021,0.3410702188312801,2.9886562388422653,0.1753171355669766,3.963793103448186,0.5851918189129899,2.268334344058144,0.5971828177955404
3HFM,K526D,2.0766666666666675,0.0022757459624595,1.557923884935405,0.0195579601146082,5.528965517241364,0.0816503053328689,4.297642480588645,0.0247060338974096,5.764942528735603,0.4110430005031603,3.338057684887101,0.3186068907088246
3HFM,K526E,2.842528735632186,0.000586094196961,2.917328645832337,0.0748221408088071,4.674942528735688,0.7053997235488773,3.680890160546732,0.1524588854375777,6.339885057471178,0.1419652375857482,4.064010444311778,0.6673515744336727
3HFM,K526G,2.483333333333283,0.0869708676925344,1.7013945255543483,0.2142107513558295,5.368735632183918,0.2687105088400885,3.928780079632638,0.342698829979706,6.095977011494185,0.0172880594134315,3.02790756372355,0.0378040734200114
3HFM,K526M,-0.0839080459769613,0.0004876598491196,-0.0877537797039141,0.000986093842096,1.693793103448314,0.411299992674549,1.335185973622715,0.51107904121216,1.8451724137930376,0.2136089306829932,0.3234531934672356,0.1701889420238416
3HFM,K526R,1.2282758620689826,0.240091199037341,1.3053881130691092,0.1592316943742955,2.3804597701149466,0.4728193018672871,3.094878780257073,0.2060083113830741,2.856436781609104,0.1912723804687554,1.692009108924349,0.3790201759676141
3HFM,L504=,5.2254497025690703e-14,0.4385687576187428,,,0.0,0.0,0.2835586837604699,3.6975719071099874e-14,0.0,0.0080492604138036,-0.9692118918653888,0.0359413840181428
3HFM,L504A,2.1254022988506254,0.0238920149613667,2.799635280750941,1.5343935726646287,2.6902298850575463,0.0026008525285146,1.830982368541608,0.053195199257906,3.797701149425335,1.0674892290148066,1.743018851426972,0.5882527111405851
3HFM,N31=,0.0,0.0,,,5.2273000742767785e-14,0.1597266127826534,0.550082521113541,0.443140831381991,-1.0453964083279033e-13,0.0014629795472848,-0.638081528623979,0.0016370813667523
3HFM,N31A,1.8131034482759536,2.220446049250313e-16,0.158911110433235,0.0,1.2273563218391197,0.0026160475119428,1.2296216593878706,0.0024976173589795,1.192988505747011,0.0079451814523329,-0.3975447752026903,0.0074104051647843
3HFM,N31D,2.1924137931035084,0.0,1.302782753170149,0.0484938249721146,1.0740229885057528,0.001567607091605,1.7548553453686129,0.0034816942277409,1.3608045977010903,0.0079651108685345,0.2072393649396171,0.0016241260493869
3HFM,N31E,2.5868965517242786,0.0,1.3270320519820322,0.0520312142658994,2.2426436781609684,0.0032469992854335,0.8987706233662967,0.0007543750757482,2.392873563218311,0.0008127664151747,0.7581170747094469,0.0009543336511043
3HFM,N32=,0.0,0.1144375112541277,,,-5.226953129581583e-14,0.0150710651982618,0.8233177216306465,0.0244121864345519,1.0454600148553557e-13,0.177183078504239,-0.1815444833860003,0.518607212395404
3HFM,N32A,2.0259770114943287,0.1196604170348127,1.7050325934850736,0.0983288336710147,2.56885057471261,0.0014448051827841,2.5665511213636214,0.0048992389047531,2.40505747126447,0.00422638535879,1.9055507920208177,1.5816178003242212
3HFM,N448=,0.0,0.0,,,-5.2273000742767785e-14,0.1706003481681034,0.6519784052247998,0.2851585355505703,1.0453964083279033e-13,0.0104376423768199,-0.6339920688704861,0.0080976340612356
3HFM,N448D,1.0752873563218934,0.0006502131321101,0.7231883452066895,1.5632557315923106,1.0997701149425003,0.543707150936687,0.8674378561053523,0.0016989274099384,0.8649425287357472,0.1741057213866763,0.1466499665573416,0.5307224531074438
3HFM,N448K,0.4979310344827448,0.0,-0.0445602723914493,0.0569308161828291,0.4313793103446888,0.8800959753810184,0.6260809600775737,0.2477664012231146,0.4894252873564046,0.1755595775782057,-0.2584435281250571,0.5305344547344775
3HFM,N448Q,0.2558620689655825,0.0,0.9763425394215316,1.5397778731739735,0.5387356321838441,0.000905058376315,0.8448086595083639,0.0010360025309666,0.3121839080460694,0.0,0.4721837663319301,1.5791206636773678
3HFM,N522=,5.226953129581583e-14,0.0230842832387473,,,1.0454600148553557e-13,0.2678878104356797,-0.0229355049903372,0.3031916595569293,5.229150445984487e-14,0.6956530563376296,0.5932994501515806,0.7991471916233878
3HFM,N522A,0.3947126436782358,0.1297370736674395,1.885486422634967,0.1134846418185503,1.185632183908157,0.00357617222668,1.3923639135674193,0.0002506406253585,0.9164367816092428,0.0033353145122847,1.8488259606138155,0.0165021263458229
3HFM,Q53=,5.22696758561055e-14,0.0020753413891229,,,7.228014483236696e-20,0.0014898254478746,-0.0395113022079709,0.0008909664645634,-1.0453964083279033e-13,0.0033353145122848,-0.0029252798252458,0.0029429166163667
3HFM,Q53A,2.3427586206896627,0.2559683661423382,1.9392810083146008,0.0972698889347665,0.8465517241379059,0.0146487477465559,0.4633291240114254,0.0163759277076861,2.2799999999999754,0.0004300755617158,2.169237958443313,0.0009713901203462
3HFM,R450=,1.0453212369772777e-13,0.1795600236340768,,,-5.226953129581583e-14,0.0050757246358603,0.0988393957036011,0.0128621644319201,-9.251858538542969e-18,0.1416202973704869,-0.3618412637824177,0.4125052933269713
3HFM,R450A,1.479310344827678,0.0028342133347585,1.2623658866066074,0.002559153399392,0.8789655172412673,0.4630655747473145,1.2930285627907974,0.0138114493910786,-0.2875862068965986,0.1149541373448283,0.3439379451009146,0.1036690481785752
3HFM,R450E,1.4233333333334162,0.0142602872820895,1.7917284222437893,1.5282112243186068,0.8867816091952623,0.0076400043024794,0.6507234982123219,0.0046573504321267,0.4513793103448431,0.8614992293569338,-0.0198409821502965,0.6795808327150921
3HFM,R450G,2.047931034482812,0.4592441819501333,1.5997917661150431,0.1885863840683363,0.767356321838968,0.7147444564297842,1.2146257874455213,0.3419377534938602,0.1314942528735377,0.1362413749465531,0.4837241411682065,0.1243406768949453
3HFM,R450H,0.7141379310346094,0.520176677608769,0.8045644493238108,1.366594086941465,-0.1978160919541279,0.2768282410024534,0.2537712465492592,0.1031584616818946,-0.5552873563218541,0.0986762697386657,-0.2912624227745505,0.0037753131487526
3HFM,R450K,2.0873563218391684,0.0983264640849138,1.4669023959140235,0.1782667224356832,1.6096551724137302,0.3906789520807198,1.5502852264761973,0.3594960953133197,1.086206896551703,0.2694990778084848,0.7182026194034514,0.127358237419542
3HFM,R450M,-0.1904597701148555,0.0019775460384206,0.395024245540769,1.488266884279111,0.4752873563217073,0.2659371710393491,-0.112694346008792,0.2744443618135508,-1.753103448275909,0.0410931998846788,-1.579312084051457,0.0015976638021059
3HFM,R450N,0.4649425287357974,0.0,0.8935104912464226,2.365448962127177e-12,-0.9232183908046676,0.2953727343316056,0.3990244713484692,0.4111214321695888,-1.5564367816092146,0.3450293662503329,1.307493847758796,1.5219146035219666
3HFM,R450Q,1.116206896551856,0.9783281594541228,0.6023938761750967,0.1290445756336048,-0.06804597701161,0.0124721912892449,0.1421136321888669,0.0054064437442899,-1.4944827586207363,0.4092542576813566,0.5428543185019605,1.4557800944190165
3HFM,R450W,-0.8558620689654549,0.0031013189800419,-1.9288779492981327,0.0023182335832335,-2.098160919540271,0.4819000849773559,-2.434602758848029,0.026910765329427,-2.837701149425352,0.0048467054350065,-3.010059775050044,0.0012680741370914
3HFM,R502=,1.045413755562663e-13,0.0934429739345353,,,5.2273000742767785e-14,0.3010486801741862,-0.0298657354171714,0.4161882843965064,-1.0454021907394901e-13,0.0140182769548936,-0.2863883154711517,0.028092171799534
3HFM,R502A,1.7357471264368467,0.4992011321893853,0.0150495911041083,0.3011243260484596,1.2443678160920089,0.0001625532829906,0.1516842574920079,0.057029812080798,0.8052873563217182,0.0651504149049862,-0.2704159246573992,0.038416702342347
3HFM,S245=,1.045396046927179e-13,0.0006502131321101,,,1.5680943134016005e-13,0.0,0.1485183310581896,0.0288354929591019,3.700743415417188e-17,1.08110424652834,-0.1482687240833138,0.585848123940264
3HFM,S245A,0.0009195402300201,0.0001625532829905,-0.8429110277575091,0.0813942943757068,0.2155172413794671,0.0,-0.2547082570085171,0.0,-0.9331034482759072,0.0170246919913985,-0.9898815787144633,0.0380221896418001
3HFM,S529=,-5.226982041639516e-14,0.003901278792735,,,-1.045396046927179e-13,0.0029663190575611,0.9922971493051592,0.0366878131322489,-1.5681090685208213e-13,0.0366015708691948,-0.4682673446827669,0.0003947680931218
3HFM,S529A,-0.5189655172414169,0.041010811292727,-0.514617646802895,0.1508815322785549,-2.1851724137932043,0.6579775399839191,-0.5448861082230508,0.4708612667466149,-1.4505747126438748,0.0218856128587711,-1.858512959654987,0.0257001795638058
3HFM,T518=,0.0,0.0011378729812297,,,0.0,0.0,0.3313246700330789,1.8474763863539243e-14,0.0,0.0,0.0068416406718134,8.673617379884035e-19
3HFM,T518A,0.9256321839080848,0.0127612092227351,0.4478910367026463,0.0859233110924995,1.108965517241343,0.0,0.5514524931991924,0.0,0.963448275862024,0.0,0.5855773811101934,0.0
3HFM,W312=,-1.5680975036976485e-13,0.270181307572483,,,-5.226953129581583e-14,0.012106673441358,0.9304361612766736,0.0493335367357481,0.0,0.5257064401326795,0.295906773718845,0.555879009970802
3HFM,W312A,2.137126436781435,0.2398178284260756,0.7422064885046068,0.1954680180178697,2.6498850574712223,0.2966821863968163,1.6872285556122284,0.0308389419840168,2.260229885057444,0.0323530040560026,1.658999641549233,0.0184098512460578
3HFM,W312F,-1.1381609195403917,0.215046812246252,0.2026769035252993,1.453085864228458,-0.9763218390805284,0.1856273085727003,1.254947926764301,0.2978578401157908,-0.8806896551724962,0.0169211643398527,0.53471177358497,0.030491699361149
3HFM,W492=,0.0,0.4887977220754005,,,0.0,0.0,0.4002135300293728,0.0035858440048187,5.2254497025690703e-14,1.0349217842352434,0.5822749104881114,0.4888748342261043
3HFM,W492A,3.8333333333333752,0.0,1.2481394442666092,0.0817931934991904,3.6006896551724688,0.4318778874990763,0.8135673902458737,0.2766523072452373,3.3567816091954747,0.5642167787219889,0.8138544178652003,0.3492066442429786
3HFM,Y247=,-5.227068777813315e-14,0.0449832252464504,,,1.5680049851122634e-13,0.26197129658141,0.8244433475984915,0.2241223106055078,-5.229150445984487e-14,0.7575864946452331,-0.4182168382428359,0.7316337667180451
3HFM,Y247A,2.136091954022969,0.0046633247759359,3.492116935605642,1.499483518721748,2.9544827586209195,0.3543733152458539,2.4593067518074365,0.0342698674261959,4.353448275861965,0.0014629795472846,3.725226369504829,0.0005265351060545
3HFM,Y247F,-1.6803448275862234,0.2710842476224416,0.5734304908796782,1.637833765361997,-1.2480459770113577,0.0721818946933549,-0.5926383492814025,0.24224654926321,-0.5657471264368891,0.6841406153389469,-0.5655489214729025,0.6591566862208826
3HFM,Y247L,0.5667816091954069,0.2349099106853683,1.1503128249959726,0.1691709659173771,2.0398850574714555,0.6225023976159595,1.3905436846643244,0.2662352417106088,1.866436781609124,0.899388982411489,1.243403044891604,0.7657162791667751
3HFM,Y247W,1.6779310344828058,0.1625730320555983,0.3261330230996191,0.2040628892363984,0.5106896551725949,0.174949249950137,0.0873810600753011,0.2163961531108962,0.8693103448275457,0.3301602440661365,-0.3432903319847241,0.3154713549044595
3HFM,Y264=,-5.227068777813315e-14,0.0295064434003745,,,-5.2273000742767785e-14,0.1762302509060056,0.4311940442033213,0.0458540354185181,-1.0450899405138141e-13,0.7348222373054568,-0.3636247644998412,0.7124307450114329
3HFM,Y264A,4.999425287356309,0.2845133850924008,1.2872345343517193,0.3013241418251368,4.618390804597734,0.35569589068957,2.924081656589804,0.2048586095937297,4.181839080459674,0.3029051216954887,1.987575507175551,0.0211568515185788
3HFM,Y264F,0.9849425287355754,0.0225966604454512,1.8096003283793856,1.5079417970635447,1.0459770114942424,0.488496064812824,1.6703901949744768,0.587873966264936,0.9537931034481976,0.5079868119707203,1.038099953923628,0.5818516509017106
3HFM,Y264L,4.591839080459726,0.6696712318193003,2.5571550372876963,1.8163378211559944,3.389655172413768,0.4375000443538743,1.5328900412460025,0.3736445257497393,3.151494252873473,0.0093775071514079,0.3833982129248105,0.0063972870793885
3HFM,Y267=,5.2269748136250335e-14,0.0020367867984726,,,-1.0450899405138141e-13,0.4816213478838372,0.0801247431450744,0.4584573710497331,-1.567634910770721e-13,0.7783864085258045,0.4947522224466442,0.5882878461199417
3HFM,Y267A,2.4541379310344955,0.0041506827781966,2.3100250459663,0.0811245823420338,3.573563218390665,0.4508494646707244,3.000023839376233,0.624160986852315,3.785747126436642,1.064396278261981,4.074747480817364,0.8237872782933726
3HFM,Y267F,-0.1124137931034035,0.0018318824655619,-0.2854972527083891,0.0789668782979129,0.5972413793102302,0.318524682422238,-0.5749940949111068,0.3126800115901381,-0.4794252873564582,0.0,0.0384143004309627,0.0
3HFM,Y267L,1.0182758620690089,0.4966031529348486,0.5335403640700097,0.2468579834577468,4.148160919540119,0.2888481276567451,2.252237281981338,0.1581610761999542,3.033103448275696,0.7730221502740482,2.2934909110091244,0.5675122067583835
3HFM,Y267W,0.8050574712644093,0.126455693465503,0.305599668730343,1.2442277687625576,0.4658620689653993,0.1123243185747326,0.6639093684961854,0.278618112208466,0.078160919540002,0.7783051191542983,0.3097828671325678,0.5825578249120493
3HFM,Y272=,-5.2268374813498524e-14,0.1069971100373871,,,9.251858538542969e-18,0.2739306428522053,0.3608081395850735,0.0545433819746059,5.2273000742767785e-14,0.1169431636631275,-0.4786518730784285,0.2147914998340765
3HFM,Y272A,1.1813793103448038,0.0022757459624596,0.5913233444751879,0.0787171663324026,2.462413793103474,0.1066650564682189,1.6249327016793875,0.0935753166718701,1.0187356321839405,0.0934392977547917,1.1529597380422274,0.0051557509329169
3HFM,Y272F,-0.4593103448277016,0.0038432766660505,-0.7223182713125592,0.0058296650144096,0.2480459770114829,0.037720418400753,0.397927417151035,0.0636867045614997,0.2541379310345626,0.0800807163157103,-0.3775428873968953,0.1415997838510677
3HFM,Y272L,0.4225287356321237,0.0030454347815091,1.0738320738401257,1.5002780025559843,0.6688505747125868,0.0453080645810857,0.9204574193547588,0.0252083861899245,0.6656321839081175,0.2788835014815807,-0.0550687502141306,0.3807323427803239
3HFM,Y449=,0.0,0.6129084631913391,,,1.0454600148553557e-13,0.525151495295392,0.6870194921848897,0.5830676287582516,-5.2273000742767785e-14,0.6541144715122478,0.1960385002272839,0.5673802860060723
3HFM,Y449A,3.4655172413793207,0.4961133388379118,1.3289438488987046,0.514381264086197,2.8419540229884954,0.0885238076810868,1.3743840933009508,0.3223176776060868,2.900574712643589,0.8075659371014283,1.8526372361763304,0.6095026743012228
3HFM,Y449F,0.1803448275862023,0.452385786676343,-0.1613275706350923,0.2417110022840932,-0.1327586206895736,0.1460358284982532,0.1898077278761597,0.2419678538174707,0.3444827586206194,0.6536923593105557,0.2730410772237415,0.7407589061487394
3HFM,Y449L,2.822758620689602,0.0012695817261119,1.617055693821688,0.0084131377363238,1.2916091954023603,0.0968865295262995,0.2883456323599117,0.1437764862294972,3.136896551724053,0.1949013863546482,1.2781445387274246,0.240793174645069
3HFM,Y50=,-5.228225260130633e-14,0.3483056775674632,,,-1.5680975036976485e-13,0.0179516533382235,0.9042177926348368,0.0175669263005455,1.5680049851122634e-13,0.2045989280603653,-0.2603147009662719,0.5129265760222773
3HFM,Y50A,2.831034482758529,0.2482190228679117,1.3384104062615003,0.14380537921371,2.6633333333331035,0.0163816291966113,2.2243699359467364,0.0248632368030522,2.773908045977199,0.1542219507521245,2.2958161191927924,2.052884628680097
3HFM,Y50F,-0.7022988505747795,0.1174590046912406,0.8554876767170597,1.4008330005317202,-0.0144827586208698,0.0108546164302089,0.8394904623013378,0.003632827238136,0.2783908045978609,0.1131526152361413,-0.5871752086221901,0.2272031138210969
3HFM,Y50L,1.8421839080458773,0.3780187344059439,0.970307196680133,0.0227876350385546,2.333793103448129,0.2193259470581833,2.3309670829851075,0.2009335411279521,2.293448275862223,0.1398116053058964,0.5794792847931624,0.2399041375086361
3HFM,Y96=,-5.2273000742767785e-14,0.2704939380794667,,,-5.2254497025690703e-14,0.4844851174592406,0.4698251345792613,0.394555359156587,1.045413755562663e-13,0.0457006059312243,-0.1460228456625864,0.0207584831017466
3HFM,Y96A,3.726781609195324,0.1343843829202043,0.8865598335630458,0.0161783051693005,2.6442528735631265,0.0,1.1414088417440529,0.0,2.84505747126452,0.0083537206026089,1.109904151546665,0.0036214553510978
3HFM,Y96F,-0.3737931034483226,0.221581769657965,-0.3209305727977016,0.0324976115039268,-1.3564367816092922,0.0035278182191452,-0.2614533718758071,0.0144305017997312,-0.730574712643547,0.2418098513869634,-0.3727404750241309,0.0019040849688097
1JTG,D311=,0.0,0.0,0.0504956460665574,6.938893903907228e-18,0.0,0.0,-0.3278258656515893,5.417535389479713e-09,-1.0453964083279033e-13,0.0024382992454501,0.0091315995701086,0.0024806849629298
1JTG,D311A,0.6420689655171122,0.0,-0.543986100630781,0.0,0.606551724137936,0.0009753196981652,0.7788859628646668,0.0017652719071255,1.2457471264367517,0.0035761722266799,-0.1390817204205684,0.0037070777136603
1JTG,D425=,0.0,0.0,0.0116343818229523,0.0073393523599103,-1.568091721286062e-13,0.005590982302077,-0.0021810850532723,0.0030234397148688,0.0,0.0,0.0131239404670369,0.0039000075998094
1JTG,D425A,0.8386206896550997,0.0,-0.0476939806878425,0.0,0.765747126436655,0.0031977994812256,-0.1301237099285091,0.0032930331351754,0.7158620689655248,0.0,-0.066595849386964,0.0032075225941941
1JTG,D425K,0.320344827586237,0.0,0.0990234739899393,7.391864468919837e-14,-0.3556321839081041,0.0063458270077412,-0.5689315550590625,0.0021069022579094,-0.6289655172414031,0.0,-0.6435205292619612,0.0039000025878398
1JTG,E143=,5.226978427632276e-14,0.0004876598490456,0.0436643545016595,0.0025047173196613,0.0,0.0,0.0195133957765193,0.0221900892713625,-1.0454600148553557e-13,0.1103578775808057,-0.0080583893870801,0.1134712540723117
1JTG,E143A,0.2472413793103787,0.0,0.4396908178896724,0.0,0.1417241379310545,0.0,0.2668388643335926,0.0221900892713995,0.1516091954021897,0.1116741054426224,0.2784558427402384,0.111445513805948
1JTG,E143G,1.1096551724138972,0.0,0.5265474255078327,0.0,0.9444827586207007,1.1102230246251563e-16,0.2847454791782215,1.2321430730185753e-08,1.018160919540041,0.0,0.3795498720418091,0.0
1JTG,E146=,0.0,0.0,0.028296869862207,7.392028006647428e-14,0.0,0.0,-0.0004293561533061,1.2380752066318174e-08,0.0,0.0,0.0758899450166327,0.0
1JTG,E146K,0.1279310344828435,0.0015676070916049,-0.9808484538212076,0.009041095793911,0.0475862068965241,0.0282842712474583,-0.9179843164412532,0.0048113530138972,-0.2944827586207825,0.0,-1.1470091158994835,0.0
1JTG,E213=,0.0,0.0,0.0366181358450721,0.0,5.226982041639516e-14,0.0016255328303493,0.0164805277039045,0.0015173857860069,0.0,0.0,0.0611298880845612,0.0
1JTG,E213K,0.1106896551725405,0.0,0.2784580172898006,0.0,-0.3596551724137822,0.0001625532829905,0.4623770506946809,0.0048725705755896,-0.4429885057471574,0.0006502131321101,-0.1120692212547008,0.0063672116051387
1JTG,E293=,5.226953129581583e-14,0.0087778772836353,0.1240350909377192,0.2190097432523027,5.226982041639516e-14,0.0026008525284407,-0.5217451098134142,0.0030408930407463,7.228014483236696e-20,0.0010659331603991,-0.0023274145340779,0.0012512167649762
1JTG,E293A,0.9852873563218524,0.0011378729812297,0.9913921079806256,0.0014965877028856,1.2301149425287614,0.0059348646636321,0.2664096969182088,0.0233972941308051,1.0440229885057568,0.0030105289319096,0.8674461502319879,0.0005827675095291
1JTG,E335=,5.2269811381377074e-14,0.0001625532829905,0.0140171821292552,0.0071034525318048,-5.226953129581583e-14,0.0047891187715088,-0.3836788756630921,0.045663377496622,-5.226982041639516e-14,0.0031140729158852,-0.1382293392997644,0.0080926881418744
1JTG,E335A,2.421609195402324,0.0074615321227963,1.6649034404019467,0.0165308927680245,0.4097701149424305,0.0043889386418546,0.2110478234624355,0.0522791582799659,2.2588505747126484,0.0014448051827839,1.631479781146962,0.0088384538592592
1JTG,E335M,1.4414942528736348,0.0025804533701977,1.2724908787535685,0.0175578666093365,-0.8998850574713894,0.0271969665604706,-0.4274803865884689,0.0154285692352808,0.582643678160915,0.422417249184401,0.482056811141586,0.4218511230517161
1JTG,E79=,0.0,0.0,-0.0127769915807534,0.0,-5.226978427632276e-14,0.0009887730192073,0.0560405733374958,0.0383028774080183,0.0,0.0065021313212496,-0.1642812376892563,0.0207548360741934
1JTG,E79A,2.067701149425239,0.0042357530512031,2.0006375638445992,0.0108510911050826,1.8021839080458824,0.0013888558589793,1.6087475421489157,0.0217082370661796,1.2621839080459505,0.0,0.8995228193536039,0.0038820334667594
1JTG,E79D,1.673793103448212,0.0,1.6788001810244106,0.0,1.567816091953904,0.0028574259528026,1.9084529676260955,0.0263558373489187,0.5924137931035002,0.0898919655163398,-0.3216487523842711,0.1112711151699858
1JTG,E79K,,,,,2.7173563218389845,0.1719822952970057,2.638872448601119,0.3383577839471813,4.468160919540235,0.0330822888952743,3.5790170836194246,0.1629283662705877
1JTG,E85=,1.0453964083279033e-13,0.0019506393964044,0.0331372857445607,0.0009538731753443,0.0,0.0008127664151007,-0.3467517935428599,0.0232248970961485,-1.045413755562663e-13,0.0553896584998318,-0.2775434593172315,0.0097830077918562
1JTG,E85A,,,,,0.8875862068965233,0.0413700500493494,1.4111593848349069,0.4448029362225276,0.023678160919503,0.0159774249512224,0.4381258107828583,0.0969546681275478
1JTG,E85G,1.901724137931148,0.0211050258594299,0.9259893536505088,0.0214558888978298,2.2505747126436177,0.0066049461602335,-113.52254367349474,0.0106043883475854,1.2664367816091466,0.0484073196488209,0.5667388430595242,0.0148324884790575
1JTG,E85V,-0.9055172413791714,0.02053003561294,-0.2304254641244526,0.0158943846339226,0.3680459770114156,0.0058519181891395,0.4482073924435454,0.0214063092148079,-1.2059770114943271,0.0655240972415946,-0.7929451243444942,0.1251847708110732
1JTG,F298=,-1.0453906259163166e-13,0.0196689472467396,-0.0258247699608629,0.0157101471669982,0.0,0.0,-0.3976632992673812,1.2321393754508348e-08,-1.4456028966473392e-19,0.005623967734559,-0.1237608130823618,0.001061769079233
1JTG,F298A,3.1618390804597483,0.0,1.6218209280664115,2.220446049250313e-16,0.7086206896551159,0.0,-0.3733577685661344,0.0,2.480000000000002,0.0,1.0013063080990332,0.0
1JTG,F404=,1.5680946124918556e-13,0.0032510656606248,0.0260763418297453,0.0001494829878552,1.0453956855264552e-13,0.0009887730192133,0.0125918316215334,0.0031261296932672,5.227068777813315e-14,0.033690908105051,0.1892572884975609,0.1217976458143921
1JTG,F404A,4.942183908046116,0.0,3.631973994116253,4.440892098500626e-16,4.080574712643807,0.0311318184111352,3.4633034537368097,0.1060795646708189,5.047471264367922,0.1273611974667375,3.7338500301323614,0.1266100530664622
1JTG,G212=,0.0,0.0,0.054404996961176,0.0,-5.2268374813498524e-14,0.0590068417403668,0.1609584756925116,0.1908954775302691,0.0,0.0077532974501553,0.0455413478471461,0.0187821524461815
1JTG,G212S,2.071724137930969,0.0,0.0743563488934854,0.0065748093983386,3.4443678160918894,0.0993200559321592,0.1815540938425339,0.1875769035141887,3.948620689655181,0.1653994632044557,0.176955322657255,0.1633791090069161
1JTG,G310=,0.0,0.0,0.0485512859919337,7.391864468919837e-14,0.0,0.0,0.0135415707656397,2.5533235978286364e-08,0.0,0.0047028212748149,0.0311103800652943,0.0205704409073955
1JTG,G310A,1.6086206896551598,0.0,-0.2365644909214724,0.0,2.5317241379310684,0.0,-0.6342061133811209,0.0221900775393193,1.8782758620690057,0.0,0.0413744093951198,0.0038996618898888
1JTG,G403=,0.0,0.0,0.0031485039062317,0.0,0.0,0.0109491431761914,0.1093836719028383,0.0128333441521654,-5.226982041639516e-14,0.0029259590945697,0.0188551151925811,0.0200378552211918
1JTG,G403A,0.831724137930968,0.0,-0.1476914155328217,0.0,1.3162068965517266,0.0059748006521062,-0.0061945530796947,0.013438868502528,0.5117241379310081,0.0,-0.5492441489288217,0.0
1JTG,H303=,-1.4456028966473392e-19,0.0064511334254874,-0.0485949190106007,0.0014935873880545,-5.226982041639516e-14,0.0067591680128651,-0.4422122119478768,0.0237842632182145,0.0,0.0001625532830645,-0.1308383296397038,0.0039925623748811
1JTG,H303A,3.280344827586179,0.0325175643868855,0.5908662289195344,9.793800778764e-05,2.855632183907947,0.0247080990207784,0.160406542312108,0.0138927039957895,3.0014942528735964,0.0014448051827839,0.3215345164791096,0.0037921458717142
1JTG,H410=,-5.226982041639516e-14,0.0024055689122094,-0.0104500821602748,0.003175251421839,-2.8912057932946783e-19,0.0140662607271581,-0.0123579458369576,0.0105493313913256,0.0,0.0199371452536436,-0.3412571572128912,0.0271099358960633
1JTG,H410A,2.262183908045877,0.0040048853770175,0.8373027758237175,0.0011163980478958,0.9377011494252762,0.0032019283395781,0.6230336677166394,0.0618434246907921,2.205057471264442,0.0035761722266799,1.008986939301321,0.0309049201786577
1JTG,K208=,0.0,0.0009050583762885,0.023888051932929,0.0009478558256922,7.228014483236696e-20,0.0014898254478746,-0.1389276728348537,0.02291167570218,0.0,0.0,0.0421369582240861,0.0030087525455495
1JTG,K208A,-0.8878160919540415,0.0004876598491196,0.0958624278669519,0.0003255792558759,-0.8395402298850675,0.0022757459624542,0.0718153116777468,0.0221317277525637,0.0255172413793341,0.0,0.1064596066272974,0.0
1JTG,K336=,5.227068777813315e-14,0.0438893864184724,0.261167488407545,0.0113761163808425,-5.226982041639516e-14,0.0030105289319096,0.0422953460926545,0.0263027223023671,0.0,0.0,-0.1749703627776147,2.775557561562892e-17
1JTG,K336A,-1.050114942528784,0.0011378729812298,-1.4784957054921142,0.0001531916869436,0.9417241379310064,0.0067591680128767,0.5356657754863141,0.0270912346656931,-0.8260919540229769,0.0020367867984726,-1.7919313481793169,0.002150872803545
1JTG,K86=,-5.226982041639516e-14,0.0005860941969405,-0.0175030208441151,0.006630745713274,5.22696758561055e-14,0.0020302898543512,-0.4377183390134037,0.0295164344102278,5.2268374813498524e-14,0.0607290450367779,0.0973158179142213,0.0979006685016475
1JTG,K86A,0.1312643678160196,0.0009753196981652,-0.2999966614122278,0.0005206942439739,-0.0997701149424171,0.0408008740408381,-0.955159446666062,0.034542147930732,-0.7942528735630972,0.0572808339306692,-1.1771326561720656,0.0288972743526864
1JTG,K86N,0.168045977011493,0.0028201940566375,-0.5734878935141103,0.0044944552808238,-1.302183908045893,0.0040246302069369,-1.3990208867921448,0.0332776199908846,-0.7641379310343942,0.115559379287726,-0.7893014383439394,0.1041448728169047
1JTG,L77=,0.0,0.0,0.0294334706534849,0.0073394558166257,-5.226982041639516e-14,0.0014629795472848,-0.4263592901651955,0.0034484547887323,5.2270109536974495e-14,0.0101514492715964,-0.2005533288130554,0.0171731327495573
1JTG,L77A,3.476206896551717,0.0004876598491195,0.5229908534428088,0.0035458016682368,3.389310344827543,0.0029259590945696,-0.4267775615411843,0.0001983463073118,3.134942528735724,0.0513706953614602,0.7321035268559767,0.1481176955673855
1JTG,M104=,-5.2269856556467583e-14,0.0010151449271756,0.0329096593456294,0.0093336200836794,-1.0453964083279033e-13,0.0014629795472848,-0.4910645379292309,0.0026505273653369,0.0,0.0074774510194149,0.1646493830449098,0.0201462655972935
1JTG,M104A,1.0455172413792062,0.0,0.8345636383167183,0.0,0.9160919540228086,0.0016255328302754,0.1830801175869912,0.0012140433440979,0.5772413793103374,0.00043007556166,0.3652042086814513,0.0017189714873399
1JTG,M244=,-1.0453674962699705e-13,0.1718188201642191,0.0521819875227485,0.0030935500294895,5.226982041639516e-14,0.0004876598491195,0.0606008615962351,0.0251003925687047,-5.2270109536974495e-14,0.0066646846042402,0.0642023703541007,0.0041368690941663
1JTG,M244A,1.3609195402298495,0.1716562668811546,0.4783105848241837,0.0059901161777029,0.7568965517241945,0.0,0.7379869132756047,0.0221900596766264,1.169770114942492,0.0,1.6857712205226811,2.220446049250313e-16
1JTG,N351=,0.0,0.0,0.0062298825497791,7.392068894076081e-14,0.0,0.0,-0.0030954414939943,1.2321393764321428e-08,0.0,0.0,0.0008963160452963,1.0842021724855044e-19
1JTG,N351K,-0.0182758620690821,0.0,0.0017246353301178,0.0,0.1110344827586608,0.0,0.0129320931481764,0.0221900831107,0.0188505747127206,0.0001625532830645,0.000235040784148,0.0062905215764665
1JTG,N75=,-5.2273000742767785e-14,0.0848697836047229,-0.2118418219496843,0.152316935901784,0.0,0.0,0.0720156322395478,0.022231457247584,-5.226982041639516e-14,0.0014629795472848,-0.0854689961244375,0.0024809092234058
1JTG,N75A,-0.4233333333333848,0.0006502131321101,-0.6575433493652855,0.0007781831717304,-0.5586206896551348,0.0,-0.6835596478729702,0.0221917075471004,-0.1331034482760076,0.0,-0.426290991665061,0.0
1JTG,P82=,-5.226978427632276e-14,0.0006502131321101,-0.009009822570183,0.0006475396603608,1.0453964083279033e-13,0.0073275298623233,-0.411418444040851,0.0179698315531256,0.0,0.0075600384608641,-0.1640376928968891,0.0160390937900837
1JTG,P82A,1.5854022988505363,0.00043007556166,-0.1279166138933708,0.0011297546926149,1.900574712643766,0.001567607091605,-0.3803056246510221,0.0217909890670555,1.6462068965517378,0.0453951689439814,-0.2764036909359769,0.0242720807627941
1JTG,P82Q,1.5302298850573786,0.0318156268652631,-0.3408883194044037,0.1405079842844934,2.2695402298851497,0.0,-0.4944037725265154,0.0,1.579770114942545,0.004226385358864,-0.5662891386289148,0.0202051326091073
1JTG,Q74=,-1.5680975036976485e-13,0.1643413691447302,-0.1133876392471173,0.1528760148653059,5.226982041639516e-14,0.0026160475118946,-0.3482034111050456,0.0207319322175883,1.0453674962699705e-13,0.0951040900848129,-0.2685603159074914,0.1206335213107771
1JTG,Q74A,-0.1137931034485644,0.0,-0.331820827514041,1.4785037782426326e-13,0.7944827586206675,0.1178100923620215,0.1479076335042908,0.048191796436541,0.1896551724138558,2.775557561562892e-17,-0.22587098310443,0.0
1JTG,R214=,0.0,0.0,0.0012363798144168,7.392068893567215e-14,0.0,0.0007085533336917,0.0113436554254113,0.0216561864897287,0.0,0.0,0.0874450272520585,0.0
1JTG,R214Y,-0.6500000000000753,0.0,-0.0970449377307196,0.0,-0.3565517241379152,0.0161869119468835,0.3408446241944629,0.2414432028348206,-1.1519540229884984,0.031521508468087,-0.3155125265080621,0.0073807554012228
1JTG,R217=,0.0,0.0022757459624437,-1.3015927702055976,0.0036602430660951,0.0,0.1054843060811822,0.3335927399638652,0.3394550704456928,1.045413755562663e-13,0.0416678953445183,-0.3313750725227765,0.0048542048985776
1JTG,R217A,0.2234482758620644,0.1721345631609037,0.1334253677844666,0.0030518213597519,0.6981609195401856,0.0031977994812256,0.6646915907779021,0.0234273036546962,0.2162068965518123,0.0113891748721276,0.6222987690978635,0.0223190181196296
1JTG,R406=,0.0,0.0,0.0153079290340042,0.0073247760801231,-5.226989269654e-14,0.0021318663207531,0.5364271046751233,0.0241767772390804,1.0453674962699705e-13,0.1231690585753938,0.2897600083730433,0.1778921273056077
1JTG,R406A,1.5737931034483814,2.220446049250313e-16,1.011514037994669,0.0,0.8586206896551495,0.0004300755617159,0.6101312075024804,0.0022991910978892,0.5525287356323688,0.003901278792735,0.2698637824050298,0.003848619534627
1JTG,R422=,-5.226953129581583e-14,0.0203191603789237,-0.015282218099406,0.0194442956873709,7.228014483236696e-20,0.0020367867984402,0.0102030672354592,0.02235997112995,0.0,0.0,0.0263853821995023,0.0032075583613779
1JTG,R422A,1.5148275862068024,0.0226806979024042,1.5137678721416756,0.0258137593793631,1.3036781609195518,0.0014171066673156,1.3865499409014292,0.0232982325851702,1.2204597701149351,0.0014171066673157,1.2425000837009943,0.0021162942771242
1JTG,S105=,0.0,0.0,0.0628208430002448,0.0078612954099334,0.0,0.0,-0.1569646873328576,9.443255332047754e-09,5.226982041639516e-14,0.0019506393964044,0.1105346254200998,0.1186094800926068
1JTG,S105A,-0.0768965517242796,0.0,0.228252613071853,0.0,-0.1459770114942507,0.0094280904158194,0.6348922754134413,0.41030798148412,-0.0337931034482085,0.0082037084505666,0.0049381704564271,0.1356325167751232
1JTG,S209=,0.0,0.0,0.0201904622102527,0.0,0.0,0.0,0.0154735200552666,2.9745679552484434e-09,0.0,0.0,0.0361888838568475,0.0061470595413632
1JTG,S209A,0.5058620689655511,0.0,0.0959043206858982,0.0,-0.1910344827586508,2.775557561562892e-17,0.1889199924035349,7.392518891213163e-14,-0.2827586206897116,0.0,0.0285499299845218,0.0
1JTG,S297=,5.226982041639516e-14,0.0021131926794689,0.0010194069269325,0.0067870915727584,0.0,0.0,-0.4228789541742054,0.0022075681865771,5.226982041639516e-14,0.0019506393964044,-0.0692676008006908,0.0011408124001999
1JTG,S297A,0.0411494252874286,0.0008127664151007,-0.6357201890609602,0.0007145586033605,-0.0086206896551515,0.0004876598491196,-0.5786602847416131,0.0005575914772251,-0.0287356321838557,0.0016255328302754,-0.7017878624113935,0.0002359046465138
1JTG,S301=,-1.5680946124918556e-13,0.0011378729812297,-0.023152904197465,0.0030671497195191,-1.0453920715192133e-13,0.0085026400040891,-0.3329312025393795,0.0212695781170292,-5.2270109536974495e-14,0.0042606328719162,-0.0471866504996023,0.00114559208183
1JTG,S301A,-0.3903448275863327,0.0016255328302754,-0.4331198932895232,0.0042555758511653,-0.3437931034483787,0.0,-0.0423391692615741,1.2321467686236997e-08,-0.324827586206899,0.0029394739891315,-0.4579504677158392,0.0009045071562042
1JTG,S333=,0.0,0.0,0.0045087696929547,0.0073394341064191,5.226989269654e-14,0.0014898254479472,-0.3538174469230106,0.0645384687343981,5.226982041639516e-14,0.0045048087223173,-0.1405469239340352,0.0170619028508459
1JTG,S333A,0.0258620689654545,3.469446951953614e-18,0.2566831892627514,0.0073394341062713,0.102413793103457,0.0070048960851476,0.0471098464993116,0.0077204677747449,-0.063678160919498,0.0977204849021844,0.1565189502843555,0.0599138890552545
1JTG,S375=,-5.226978427632276e-14,0.0006502131321101,0.0060064484801089,0.0063791175934932,-5.226982041639516e-14,0.0075039074685108,-0.4102328324842054,0.0465553999543722,5.2270109536974495e-14,0.009878372505656,-0.1970236624768812,0.0206713189152642
1JTG,S375A,0.3149425287355548,0.0024055689122768,0.3395945847767863,0.0046696121657792,-0.0637931034483093,0.0097219910132493,-0.3539052734680777,0.0481791497926794,-0.5673563218390453,0.0016255328303493,-0.3808541666879022,0.0010143543291841
1JTG,T294=,0.0,0.0,0.4540861613804736,0.0,0.0,0.0,-0.3931133031267501,1.232131982932175e-08,0.0,0.0,-0.0238027068142651,0.0
1JTG,T294K,1.3017241379310658,0.0,0.4457387734662226,0.0,0.5114942528735945,0.0008127664151747,-0.4144813072218375,0.0011050995742952,1.3844827586206458,0.0,0.012432748174109,0.0016591727694009
1JTG,T402=,0.0,0.0,0.0159148534409211,7.392028006647428e-14,0.0,0.0023045905351532,0.0615566652098503,0.0094838063110101,1.0453964083279033e-13,0.0027634058115791,0.0154679768239924,0.0337011273544752
1JTG,T402K,0.4137931034482131,0.0,0.0149064301981995,0.0,0.3363218390804518,0.0012695817261165,0.0335773582266494,0.0019752969529052,0.497011494252986,5.551115123125783e-17,0.0610519346936671,0.0038998895501918
1JTG,V190=,0.0,0.0,0.0270931800611739,0.0,0.0,0.0,0.0015862468507785,0.0221901089027323,0.0,0.0,0.0199866060174095,0.0047889740081047
1JTG,V190A,0.9748275862068176,0.0,0.7227511356165253,7.389902765507827e-14,1.362298850574749,0.2246486371493795,0.2624115761050652,0.0814767659666509,1.7296551724138196,0.0,0.3720200649305016,5.551115123125783e-17
1JTG,V355=,1.0453961279307897e-13,0.0002815505451408,-0.0034998921728401,0.0009076957859653,0.0,0.0,0.0133829007174803,0.0221900665389624,1.045396046927179e-13,0.0002815505451408,-0.0017682693235645,0.0002693636975887
1JTG,V355K,0.428160919540324,0.0001625532829905,-0.0012110447164298,0.0002005131349697,0.4934482758620828,0.0,-0.0022483990237717,0.0,0.4312643678162433,0.000325106566055,0.0007097938759602,0.0010816301826439
1JTG,V78=,0.0,0.0,0.0353947098378791,0.0073397407569508,-7.228014483236696e-20,0.0019775460384206,-0.0097619009477119,0.0119581229755208,5.226953129581583e-14,0.0323591289282869,0.0745756925225473,0.0072676096527301
1JTG,V78A,2.440000000000008,0.0214588804770844,0.5489345432054495,0.0278089761502444,2.654022988505764,0.0023045905351533,0.8736098084604572,0.0067287899338639,2.5252873563218685,0.0175474744382866,0.712029456253731,0.0251692961307124
1JTG,W374=,5.2268374813498524e-14,0.0220623792853845,-0.0234324850791757,0.015300347177683,-5.2269657786069296e-14,0.0045165247596504,-0.3124183520931811,0.0416836647500693,-1.0454079731510765e-13,0.0248791503700005,-0.1483576209985826,0.0525475340192441
1JTG,W374A,3.4242528735632374,0.0031013189800537,2.4631687979991645,0.0047590136297373,2.5327586206895862,0.0033825147056961,1.90433392763578,0.0040448924078462,3.002988505747046,0.2949350927651871,2.126308068449488,0.2002438403799792
1JTG,W412=,1.734723475976807e-18,0.0240512949878993,0.0065704477771666,0.0169770766027151,-1.0453949627250073e-13,0.0018746559115196,-0.3180741659744676,0.0342229395286645,-1.568085938874475e-13,0.0147950279629659,-0.3388460122252958,0.0511834584603443
1JTG,W412A,3.969770114942559,0.0012272503737529,1.336800250921139,0.0013237149179103,3.645747126436712,0.0083821400706202,0.6432114470179705,0.0196823382383388,4.280804597700933,0.0916079695327494,1.2190268919385252,0.1029120682955411
1JTG,W424=,0.0,0.0,-0.007283109509507,0.0,-1.045396046927179e-13,0.0024274381703848,-0.0071774475008294,0.0074394885752175,-5.2268374813498524e-14,0.062890056463696,0.0329736625411081,0.0361040370695295
1JTG,W424A,3.908620689655237,0.0019506393964043,1.6490155678712162,0.0075342973156277,3.61885057471253,0.0027729512832077,2.011340365313912,0.0004860715064204,3.879999999999984,0.0366560356440443,1.6832469316279104,0.0243152820351979
1JTG,Y312=,-5.226982041639516e-14,0.0020753413891461,-0.039785110501903,0.0053803180060043,-1.5680931668889588e-13,0.0022347381718603,0.0323131221909597,0.025416177670388,5.2269964976684826e-14,0.0029796508958218,-0.1311077435983098,0.0110212796087644
1JTG,Y312A,4.046896551724096,0.0118797426921195,1.8232538615843463,0.0009710809253874,3.701379310344645,0.0293015537864878,3.2465222894619075,0.0642170184299428,3.0122988505748034,0.1120876494887821,1.2860619544909797,0.1227540203138705
1JTG,Y313=,1.0453906259163166e-13,0.0253583121528886,0.0148578723883474,0.0205071091308957,-5.2270109536974495e-14,0.0082902174345896,-0.36555085484488,0.0274242445557986,0.0,0.0009753196981652,-0.1056970136329547,0.0054945912584286
1JTG,Y313A,2.722183908046081,0.1815720171460198,0.6860220528813903,0.0535518805566524,2.5877011494253304,0.0031140729158852,0.987053627967511,0.0265767721632977,2.4124137931034286,0.0017126051063887,0.5308449207120572,0.001740620791522
1JTG,Y315=,5.226953129581583e-14,0.0040638320757995,-0.0156135820820075,0.0030399738803983,0.0,0.0011378729812297,-0.4126564961521664,0.0154822280814912,5.2269964976684826e-14,0.0018746559115196,0.0479060936744979,0.0008708200991054
1JTG,Y315A,4.026436781609219,0.01536708962427,1.4375074519139897,0.0135043445277689,5.211839080459753,0.0427552217163307,3.1543953663965283,0.0336910208977816,3.87551724137948,0.0016497356430327,1.50669904558239,0.0020933071140894
1JTG,Y405=,0.0,0.0,0.0096502709954526,0.0,5.227068777813315e-14,0.0643244928095947,0.2451708834753102,0.2621323978350487,-5.2273000742767785e-14,0.0781627788825677,-0.0382355328886545,0.1249581737912019
1JTG,Y405A,0.9771264367816328,0.0059681632118235,-0.2491674842774265,0.0021276648321894,1.852988505747189,0.00285742595279,0.2033323655728472,0.0291123145382652,0.9105747126436812,0.1281138514672926,-0.6633588561986136,0.1143051464503697
1JTG,Y80=,0.0,0.0,0.0090438862321991,0.0,-1.0453956855264552e-13,0.0023945593857506,-0.4171243199619249,0.017720845947741,5.226982041639516e-14,0.0047308311786656,-0.1618343599410314,0.0039667438235995
1JTG,Y80A,2.3656321839081134,0.0039450580004339,2.489312570758442,0.0115163942196818,4.725057471264283,0.0039417076320354,2.167287014265864,0.0281887960578877,2.330689655172419,0.023251938890622,2.1050505070614487,0.0071889878478724
2JEL,A517=,-5.232851189399904e-14,2.307443869807744,,,0.0,0.0011262021805633,-9.576954509570006e-05,0.000334174690641,7.228014483236696e-20,0.0031394253525477,0.001193331561902,0.0011036148837213
2JEL,A517S,-1.492183908046078,0.0011721883939529,-0.0113334223156591,0.0010060932837558,0.6962068965517,0.0012902266850918,-0.0003747495027229,0.0002693575433347,0.5504597701149672,0.0,0.002928622344245,0.0005060036370665
2JEL,D504=,0.0,0.0016009641697796,,,-5.227068777813315e-14,0.0475681569410045,-0.5571484865562598,0.0618485381467441,0.0,0.0,0.1205515245604554,0.0
2JEL,D504E,2.2418390804598114,0.0053716420439372,-0.0327866817049694,0.0018567989493538,3.004942528735531,0.2435466463581499,-0.1622512450065752,0.2911458228958059,2.661379310344775,0.0,0.0515850837225649,6.938893903907228e-18
2JEL,E440=,0.0,0.7051561417901283,,,1.5680943134016005e-13,0.0,0.0311332339944375,3.469446951953614e-18,-5.226982041639516e-14,0.0087068491330218,0.0766951412588659,0.0636133583418566
2JEL,E440D,2.495172413793061,1.80549414735461,1.5535061007303426,1.5819415179429954,0.4624137931035687,0.0,0.0411745944361114,0.0,0.3590804597700915,0.0136544757746835,0.1139673929844645,0.0737100607332228
2JEL,E440Q,0.3768965517241375,0.3004104735786446,0.301722262623785,0.3597138788753399,-0.0006896551722406,0.0,0.033897491784485,0.0,-0.0200000000000497,0.0052320950237892,0.0147537254291422,0.0073443770681617
2JEL,E501=,5.226978427632276e-14,0.0004876598490456,,,1.568085938874475e-13,0.0175557545674185,-0.4552968087725129,0.0139639719240531,-1.0453790610931437e-13,0.0243021235521194,-0.0348561234562728,0.0745327393447657
2JEL,E501K,1.390000000000087,0.0508765808247238,1.7676191187717774,0.0576950958763957,-0.3462068965516393,0.0014629795472848,-0.5768719692421121,0.0032991124352188,-0.29241379310359,0.0011378729812297,-0.142944503442474,0.0247677674973718
2JEL,E503=,-1.0453963086311521e-13,0.0028155054514723,,,-1.0453949627250073e-13,0.0036745672098954,-0.5761172513441658,0.0095086259219807,-5.226982041639516e-14,0.0008127664151746,-0.2573194070915089,0.0020573795191873
2JEL,E503A,0.9235632183906832,0.000325106566055,-0.2892214584196791,0.0315222289783652,0.1198850574711736,0.0026858210219954,-1.1205586412221948,0.0050382922845773,1.0701149425287293,0.0094280904158194,-0.5553903840748603,0.0009892772739531
2JEL,E505=,5.7824115865893605e-19,0.0073975139815036,,,-1.045396046927179e-13,0.0004300755617159,-0.5705019460679748,0.0031011138513651,5.226953129581583e-14,0.028968709913429,-0.02610405256328,0.0580092805849027
2JEL,E505A,0.2478160919540171,0.0,1.837221576780582,0.0,0.4378160919539933,0.0136612471490971,0.2225514505977147,0.004970229042093,-0.442183908045844,0.0312102303420281,0.0503851249148847,0.0653093059467744
2JEL,E505K,5.702068965517314,0.0057171632714443,4.462057762629772,0.3126201583699434,4.49804597701142,0.0152843312191572,1.588787473694287,0.0120310059557708,2.9527586206896905,0.0412885338899578,1.316941750099839,0.0253004628012095
2JEL,E510=,0.0,0.7756230027596169,,,0.0,0.0005631010902816,0.0084902026792301,0.0002330509868986,-5.2268374813498524e-14,0.1245361853487823,0.1704368596797237,0.1273146169889286
2JEL,E510R,1.9457471264367685,0.9346162407671196,1.7137159496954564,0.1024745295189723,-0.1703448275861513,0.0002815505451408,-0.2774797748008559,0.0004857869608061,2.483218390804524,0.0213502459713788,1.6527299853187394,0.0088358194090346
2JEL,E518=,5.2273000742767785e-14,0.5491096096921184,,,0.0,0.0011378729812297,-0.0011330341215074,2.4861843794173725e-05,0.0,0.0,0.002120848691092,4.9538868537463113e-05
2JEL,E518A,-0.175402298850504,0.6287560987654074,0.0071578069504874,0.0004250054965554,0.7009195402298278,0.0011378729811981,-0.000108927879462,9.476080078824284e-05,0.1757471264367811,0.0006502131321101,0.1371205145156197,0.0001304335535158
2JEL,E520=,0.0,0.0,,,-5.2269964976684826e-14,0.00144480518273,-0.0013187230721431,3.231712958250449e-06,0.0,0.0,0.0003151911083666,0.0
2JEL,E520A,-0.1125287356321625,0.0006502131321841,-0.000329424689159,3.241130868955054e-05,-0.5410344827586069,0.0021869307575058,-0.0013352973245015,1.2324087085585582e-05,-0.5704597701149647,0.0011378729812298,0.0003710141637102,6.586495854827925e-05
2JEL,E520D,0.6762068965517024,0.0031729135038876,-0.0410526630179154,0.028796883265961,0.4909195402298541,0.0556188831825139,-0.0013113611043468,5.439033353350535e-06,0.3917241379310232,0.0,0.0003114393396979,0.0
2JEL,E520K,0.6575862068966044,0.0,-0.0003765505576227,0.0,-0.0837931034482545,0.0011378729812297,-0.0013439121332454,1.9670982732275362e-07,-0.1122988505746967,0.0042263853587901,0.0003056658281287,7.327124267786803e-05
2JEL,E520Q,-0.1934482758620681,0.0531549235513012,-0.0002784888905201,1.923774400595975e-06,-0.4471264367816468,0.00601447147213,-0.0013250840823735,4.227331126219754e-06,-0.5037931034482018,0.0,0.0003332763884012,5.421010862427522e-20
2JEL,F437=,-1.5680960580947517e-13,0.0121458960282783,,,-5.226982041639516e-14,0.0046462949267125,-0.4617478512140505,0.0040334023402927,5.227068777813315e-14,0.0297685616245873,0.1077229416588365,0.0403260793398543
2JEL,F437W,2.917356321838908,0.1696248765897617,0.2084961209718768,0.1673864915355974,0.154712643678109,0.0019164749425697,-1.6437846470727695,0.002249233547947,1.7388505747127665,0.0355248661978765,-0.0135132705465638,0.043446813964912
2JEL,F437Y,2.447126436781448,1.8857929389483912,1.3891569100012238,1.5845447701236524,0.1435632183907811,0.0058519181891395,-0.3022424317182361,0.004326512393635,0.4310344827587252,0.0312102303420281,0.3826867603327983,0.0455608992004814
2JEL,H511=,5.2270109536974495e-14,0.0154903982380885,,,-5.22696758561055e-14,0.0058134108581105,-0.0375759621559039,0.0214168169710966,1.5680975036976485e-13,0.0129237527389906,0.0083883973243193,0.0042340753341624
2JEL,H511A,0.0673563218391603,0.8447894119141539,-0.047799921914974,0.0293492195595503,1.725632183908089,0.1285364838942926,0.2525413224653132,0.1235586299538146,2.025632183908156,0.0016009641697796,0.6661638286847857,0.0002657831441218
2JEL,H511D,0.6402298850575424,0.8696442493108636,-0.0973537291767424,0.0284829903135496,1.7790804597700702,0.0584116172519588,0.2761818933856961,0.0730496752567076,2.6101149425289023,0.0138227650417743,0.4112730361249441,0.0163955963350326
2JEL,K459=,-5.226980234635895e-14,0.000325106566055,,,-9.035018104045872e-20,0.0014448051827134,0.0047542925561686,0.0007382922017599,-5.226978427632276e-14,0.0006502131321101,0.0043399687198567,0.0001750626111466
2JEL,K459E,0.1542528735632296,0.0658340796277455,-0.0461822092688896,0.0288263977377826,0.2745977011494395,0.0041792319454467,0.0044019834111994,0.0003051527127031,0.0648275862067748,0.2569164280412839,0.0047047809748514,0.0026255191525792
2JEL,K462=,0.0,0.0,,,1.5680943134016005e-13,0.0,0.0038799181374056,0.0003424891502353,0.0,0.0,0.0037508239781878,0.0
2JEL,K462E,0.5613793103448815,0.0,-0.0072714086581459,0.0025954867694691,0.6591954022990221,0.0005860941970123,0.0069785702374184,0.0007626645798204,0.6333333333333585,0.000650213132184,0.004393801551675,4.103964328011918e-05
2JEL,K507=,-4.625929269271485e-18,0.0889879386044743,,,-5.227068777813315e-14,0.013313500906222,-0.5931996630544809,0.0091120751978211,1.0454600148553557e-13,0.4830684555820277,-0.5011165350915898,0.557374789602047
2JEL,K507E,-0.5857471264367298,0.8382512514295709,0.042492931627738,0.0294713445861693,0.2750574712643189,0.0159401708720473,-0.3570316672668359,0.0260640190393798,1.477816091954124,0.5097184983392224,1.211559466142905,0.2232054216197719
2JEL,K507R,0.9186206896551942,2.562141122007007,1.0014965122638972,1.7380598903720663,-0.2693103448276209,0.0081211594173162,-0.9848481642682692,0.0088104055000935,-0.3670114942527933,0.0216067496781512,-0.3954928792265867,0.0136813403400897
2JEL,K514=,-5.232851189399904e-14,1.4176294459891676,,,5.2270109536974495e-14,0.0225878885630597,0.0539795994367962,0.0355993971966886,1.0453906259163166e-13,0.0131467323019987,0.0618951225820721,0.0706276360743712
2JEL,K514E,-1.292068965517292,0.6107959239560712,0.0244162682683859,0.0013425020257623,0.2398850574713154,0.0233607788308078,0.0115886287752455,0.000580413421086,0.4596551724139788,0.0130042626424993,0.2084091810994145,0.0797809845693894
2JEL,N447=,0.0,0.0,,,0.0,0.0,-2.7128031621847687e-11,0.0,0.0,0.0,-1.7405846878757764e-11,0.0
2JEL,N447D,0.266896551724099,0.0,1.27314518161664e-07,0.0,0.3417241379310294,0.0,2.422705714205473e-11,0.0,0.2082758620690583,0.0,-2.9323363660609926e-11,0.0
2JEL,N473=,0.0,0.0,,,0.0,0.0,-0.0001106525557808,1.3552527156068804e-20,0.0,0.0,-3.5170693426435125e-05,0.0
2JEL,N473T,2.226206896551769,0.0,-0.0026983248081946,0.0026098997464364,2.2255172413792152,0.0,-0.0001914893355519,2.710505431213761e-20,2.301034482758543,0.0,2.805312650989749e-05,3.3881317890172014e-21
2JEL,P446=,0.0,0.0,,,0.0,0.0,8.389304576698562e-12,0.0,1.5680943134016005e-13,0.0,-4.150549165356567e-06,0.0
2JEL,P446E,0.7878160919540539,0.000325106566055,1.287970467953643e-07,8.75146869388404e-09,0.8344827586207147,0.0,2.093405908391137e-11,0.0,0.7731034482759274,0.0,-1.6053978658325426e-06,2.1175823681357523e-22
2JEL,Q438=,-7.401486830834377e-17,1.4286385426735182,,,-2.0907924552550835e-13,0.0001625532829905,-0.3498165494685921,0.0013853611102194,5.227068777813315e-14,0.0112161765291594,0.1067110335924522,0.0718572783482842
2JEL,Q438K,3.873563218390784,0.4631968849289873,3.489345260912201,0.4917511115926105,-0.0629885057473618,0.0011721883939734,-0.2220332399408902,0.0017113828096018,0.4428735632184506,0.0136612471490971,0.6205213467793569,0.0640341684491523
2JEL,Q439=,5.2254497025690703e-14,0.34233721406407,,,5.226982041639516e-14,0.0026008525285146,-0.4094821692796484,0.001023262716206,1.0453964083279033e-13,0.0085506735234384,0.0616365521380785,0.0688448449784893
2JEL,Q439K,2.657011494252872,1.4345633358594774,2.5732846207460818,1.1965353102583136,0.4556321839081961,0.0,-0.4460511537456438,3.694951382753912e-14,1.6679310344828595,0.045678340245685,1.2746012499544654,0.0665824177647447
2JEL,Q492=,-1.5680943134016005e-13,0.0,,,0.0,0.0,4.560880715244225e-09,0.0,0.0,0.0,1.267647442953854e-09,2.0679515313825687e-25
2JEL,Q492E,0.7999999999997428,0.0,-0.0036922420351151,0.0026084686581385,0.852413793103363,0.0,2.602017298942945e-09,0.0,0.9120689655172352,0.0,1.9036037726970068e-08,0.0
2JEL,Q506=,1.0842021724855044e-19,0.0052396649747052,,,5.22696758561055e-14,0.0075879482502114,-0.5657547181708545,0.0110070013008284,0.0,0.0261710785680632,0.0834911350810362,0.060776127398467
2JEL,Q506E,2.761609195402281,0.0450589373441701,2.962731249035224,0.1307264390052432,1.1566666666667305,0.0057171632714445,0.2131950867477376,0.0008544622614867,1.7417241379310628,0.0096318821448928,0.8729121972547892,0.0687155117374165
2JEL,R452=,5.226980234635895e-14,0.000325106566055,,,5.226982041639516e-14,0.0019506393964044,0.0001556458573497,6.836498491609033e-05,-1.5680943134016005e-13,0.0,0.0009322619611151,1.0842021724855044e-19
2JEL,R452G,1.2136781609195628,0.0004876598490456,-3.305541929290777e-05,5.29650620179899e-06,0.6902298850574838,0.0013888558590226,0.0001038603814233,4.708845526968591e-05,0.2975862068964928,0.0,0.0003415295279786,0.0
2JEL,R452K,1.0235632183907752,0.0021131926793951,-0.0001262120558122,3.42342501891431e-05,0.5258620689655485,0.0222887760154103,0.0001418463370853,0.0001219320312117,0.7351724137929679,0.0,0.0009213663718677,0.0
2JEL,S476=,0.0,0.0,,,0.0,0.0,-0.4481058234242043,0.0,1.5680943134016005e-13,0.0,0.0027894928429116,0.0
2JEL,S476C,1.315632183908036,0.0030105289318439,0.5942004657927832,0.0002377612086242,-0.1162068965517203,0.0,-0.4473487523635663,0.0,0.5417241379311613,0.0,0.0018648651986699,0.0
2JEL,S478=,0.0,0.0,,,0.0,0.0,0.0037980173677734,4.336808689942021e-19,1.0453962276275413e-13,0.0004300755617159,0.0012846822117081,0.0003938897474678
2JEL,S478C,0.9286206896550884,1.1102230246251563e-16,-0.0040476771141845,0.0026145143146399,0.9568965517241692,0.0,0.0038736825474878,0.0,0.8888505747127683,0.0,0.0020888858089478,0.0
2JEL,S481=,-5.226982041639516e-14,0.0009887730192133,,,0.0,0.0,0.00365504626549,0.0,0.0,0.0,0.0010653113265013,0.0
2JEL,S481C,0.3270114942528506,0.0019708538160498,-0.0009853638295848,0.0028893017888576,0.3003448275862395,0.0,0.0045904477146591,0.0,0.1455172413793191,0.0,0.0010001494970781,0.0
2JEL,S499=,1.5680931668889588e-13,0.0023045905351532,,,-1.5680942510911308e-13,0.000586094196961,-0.4478623355373264,0.0007408526322855,5.226982041639516e-14,0.0064223977217143,0.0107918944825636,0.0027915565901305
2JEL,S499T,-0.0548275862066715,0.0014898254479472,-0.0689408666517794,0.0028725379980182,-0.0970114942529839,0.0029259590945697,-0.4579202901695471,0.0008147458400531,-0.1445977011494035,0.0,0.0196856881279143,0.0
2JEL,T442=,5.2273000742767785e-14,0.6228236835027503,,,0.0,0.0,-0.0014237802225454,2.1684043449710093e-19,0.0,0.0022757459624595,0.0004562915466584,0.0001484508362814
2JEL,T442N,0.1670114942528706,0.0936306910260843,-0.0195250829893279,0.0301148070534411,0.7641379310346034,1.1102230246251563e-16,-0.001342979494125,0.0,0.726551724137921,0.0008601511234458,0.0010049146080693,0.0008146969363044
2JEL,T442S,0.5193103448276418,0.0050391517739648,-0.0008043360139708,0.0001971582208962,0.7482758620689905,1.1102230246251563e-16,-0.0013459655524613,0.0,0.6833333333333522,0.0004876598491195,-0.0002936761435173,8.339420482166635e-05
2JEL,T469=,-5.232851189399904e-14,0.8540549490469829,,,-5.226978427632276e-14,0.0006502131321101,-0.4428558166210448,0.0022701690692978,-5.226982041639516e-14,0.0011378729811558,0.0133371074588435,0.0002731742019867
2JEL,T469N,0.849655172413773,0.8393314693047409,0.1755779855377385,0.0031631776610662,0.2644827586206817,0.0016255328303493,-0.450590153207397,0.0034079855815998,0.4266666666665609,0.002113192679395,0.0183876062428471,0.0014124531602261
2JEL,T469Q,0.9350574712642884,0.8438687498091343,0.4814950970918791,0.0072982295404793,-0.587816091954079,0.0022347381718361,-0.4539966893822441,0.0034505531218374,-0.0485057471264919,0.0018746559115421,0.0165250746862637,0.003573213119045
2JEL,T471=,5.226982041639516e-14,0.0019775460384146,,,5.226982041639516e-14,0.0004876598491195,-0.4412752779499824,0.0003562389843852,0.0,0.0107285166800398,0.0158189703270913,0.0060282583391148
2JEL,T471Q,0.3334482758621028,0.7028008251759004,-0.3620394964937286,0.0035454322780021,0.2613793103447623,0.0,-0.4394937333881115,0.0,0.5774712643678032,0.0108180400605764,0.0159109436478617,0.0055549267895372
2JEL,T497=,5.226982041639516e-14,0.0016255328302754,,,0.0,0.0,-0.4174925790802598,7.392518891213163e-14,-2.0907928166558065e-13,0.0069195020429221,0.0220034319614444,0.0054920790215992
2JEL,T497A,1.6920689655172942,0.5650369654818761,-0.0120663296444224,0.0273430997896302,0.9913793103448276,1.1102230246251563e-16,-0.4314313150032454,0.0,1.0187356321837315,0.00601447147213,0.0538173063005056,0.0065288663163155
2JEL,T497N,0.8447126436782316,0.5678799117190331,0.0403146751952966,0.0286959261222433,0.0398850574712359,0.0041219358797797,-0.4496642070829558,0.0095385047129747,0.8272413793101491,1.1102230246251563e-16,0.1257815850173975,0.0
2JEL,V441=,-1.0450899405138141e-13,2.143833977881467,,,5.226982041639516e-14,0.0033589975163479,-0.018844048756897,0.0168291256116789,-1.0453956855264552e-13,0.0019708538160224,0.0109398923574378,0.0048212836772991
2JEL,V441F,7.6690804597700115,0.2296335981030395,3.5480536603605266,0.1590826154310579,3.936666666666748,0.0001625532830644,-0.0114197339114551,0.000634924797682,4.591264367816088,0.0028896103655141,0.0019195277457782,0.0010472384598921
3MZG,H125=,0.0,0.0,,,0.0,0.0,-0.0001318608449754,1.1240058900919624e-05,0.0,0.0035165651817664,0.000197717695405,0.0006253515364457
3MZG,H125A,1.8072413793103657,0.0716882093920265,-0.0044485380858636,0.0001835964319788,2.337356321839111,0.0013888558590377,-4.625287999062138e-05,0.0001119336780155,2.2771264367816,0.0844606273303395,-0.0001890809590313,0.0009180418350021
3MZG,H14=,0.0,0.0016255328303124,,,-2.6136500371383893e-14,0.167774124810731,-0.1524661024609747,0.2114653224209673,0.0,0.0,-0.0176294418146238,0.0
3MZG,H14A,0.7540229885057409,0.3025932310806825,0.4219930370564286,0.1599569181901842,1.088160919540215,0.0564087998614544,0.3527697952882465,0.0032248705342652,1.054252873563169,0.001444805182757,0.3742957468168881,0.0137242223261113
3MZG,H160=,2.613491020819758e-14,0.0008127664151377,,,-2.6127248512845352e-14,0.232395772235868,-0.3506558624048241,0.2461272278328971,5.7824115865893605e-19,0.0169936221744849,-0.063202567904154,0.0788341586250042
3MZG,H160A,1.0599999999999976,0.0071523444533599,0.8502323050438934,0.0021428783529543,1.043448275862066,0.1358945446142443,0.0593169316226292,0.2342020741760109,1.10068965517239,0.0131968840531499,0.7414621490787031,0.0835242648654216
3MZG,H167=,-2.616425594699952e-14,0.3811093180789287,,,2.6145752229922443e-14,0.2703790345080098,-0.5716783344216531,0.0645201186017004,7.840471567008005e-14,0.0,0.0169776451967852,0.0
3MZG,H167A,1.7937931034482757,0.4225929247204339,1.233475202023919,0.2715837368940744,0.8105747126436936,0.3927457874174583,0.4272008194265118,0.5329135810716457,1.22149425287361,0.2130454731489857,1.546649668302387,0.1126316482294718
3MZG,H17=,0.0,0.0,,,2.6136500371383893e-14,0.0730439648112706,-0.2638427306782819,0.2565997199127048,-1.0453674962699705e-13,0.1262245868304592,-0.3270120124967047,0.2183393990479597
3MZG,H17A,-0.0072413793103304,8.673617379884035e-19,0.3003884566865002,0.0134752025111304,0.0285057471264422,0.1398788710274555,0.2822405311335178,0.0146583540201375,0.0532183908044891,0.202053730808008,0.3866830894059143,0.0841372824277207
3MZG,H182=,-5.226982041639516e-14,0.0053642583400568,,,0.0,0.0012272503737676,-0.0053756234195332,0.0006058051091591,0.0,0.0076400043024794,-0.0117950793010722,0.0021581807931486
3MZG,H182A,1.15563218390803,0.0026160475118694,-0.0250915322336608,0.0009399494043043,1.142528735632164,0.0001625532830645,-0.0186843531692808,0.0011809805710596,1.3545977011494348,0.0024382992454871,-0.0285611437000144,0.0018656878406737
3MZG,H33=,0.0,0.0,,,0.0,0.0,0.0008771136001463,0.0,0.0,0.0,0.0012569706684879,0.0
3MZG,H33A,-0.1306896551724596,0.0,-0.0004944724204945,0.0,1.4186206896551052,0.0,-6.190224447546543e-05,0.0,0.5224137931034566,0.0009753196982022,0.0015194863978921,0.0001000109688886
3MZG,H374=,4.625929269271485e-18,0.1481968068679349,,,5.2273000742767785e-14,0.1737712082540603,-0.2102121508425949,0.2004164315950306,-5.2263748884229244e-14,0.1108556185296992,-0.2513173014939451,0.1817814254362123
3MZG,H374A,1.2570114942528907,0.0039114251786787,1.019973965145469,0.0133706226687975,1.4873563218391128,0.0089404305667367,1.1757662920678122,0.0104555244889013,1.907126436781568,0.0013888558590378,1.0177911382392864,0.0061448614299067
3MZG,H46=,0.0,0.0,,,-7.840471567008005e-14,0.0,0.0013730176196359,2.1684043449710093e-19,-7.840471567008005e-14,0.0,0.0019819805998097,0.0
3MZG,H46A,3.644827586206875,0.0,0.0346803621219993,0.0,3.328620689655049,0.0005631010903136,-0.0030154737906668,0.0014225936892626,3.345517241379232,4.440892098500626e-16,0.0035673586221648,4.336808689942021e-19
3MZG,H84=,0.0,0.0,,,-7.840471567008005e-14,0.0,6.824775388442253e-05,0.0,0.0,0.0,-0.0092554612949201,0.0139902817140916
3MZG,H84A,0.6977011494253323,0.0001625532830275,-0.000550174350562,0.0002202028653157,0.9382758620688884,0.0,0.0001108378289465,1.3552527156068804e-20,1.1113793103448126,0.0,0.0008874463456965,1.0842021724855044e-19
3SGB,A194=,0.0,0.1823847835612313,,,0.0,0.0,-0.2563153449018344,0.0,0.0,0.0,0.0015482841511835,6.327003616460568e-08
3SGB,A194C,0.7910344827586279,0.1762985343288566,0.0294582294561913,0.0098340108833093,0.5541379310344727,0.0,-0.2813170172091053,0.0,0.7306896551723844,0.0,-0.1131478052152174,0.0
3SGB,A194D,2.1606896551724404,0.0,1.2081390055882053,0.0,1.505862068965504,0.0,0.6165166773009474,0.0,1.613793103448298,0.0,0.9338688878071596,6.327011006546405e-08
3SGB,A194E,1.8742528735632231,0.0006502131321471,1.52312975822685,0.0049516908821687,1.9898850574712263,0.0009887730192104,1.4567850792763757,0.0760625124882576,1.1903448275862063,0.0,0.9409204098144084,6.327007311595482e-08
3SGB,A194F,-0.0642528735632148,0.1798679070815165,-0.5331265306728356,0.0105953809437128,-1.088620689655225,0.0,-1.3753105573719353,0.0,-1.6681609195401943,0.0016255328303124,-1.5121059202431166,0.0049489166087868
3SGB,A194G,2.494942528735621,0.1763703120890643,1.860736671341924,0.0152644757353488,2.3595402298850594,0.0027634058115422,1.615710281938357,0.0291640872855033,2.191379310344834,0.0,1.7261724784595216,6.327007316829124e-08
3SGB,A194H,0.877356321839111,0.1854786383229677,0.7047262386929063,0.0232508390516666,0.0778160919540123,0.0016255328303493,-0.175128005395862,0.0204459016091461,-0.4972413793103473,0.0,-0.5941310193269727,0.0
3SGB,A194I,3.387586206896576,0.0,1.859673593729236,2.220446049250313e-16,1.6144827586206691,0.0476569522431782,-0.2370869543167321,0.1696137874014128,0.3317241379310569,0.0009753196982022,-0.4213853561694007,0.0037543295062765
3SGB,A194K,1.982413793103456,0.0027151751289651,1.6702628628212783,0.0032055628426189,1.858620689655181,0.0029259590945697,1.4547210465930194,0.0054374589750366,0.9178160919540378,0.0027054258151579,0.7783633288548003,0.0021247999154754
3SGB,A194L,2.3433333333333266,0.1802715908818363,0.1111329812537426,0.0025518358813441,1.071034482758619,0.0,-0.1203509801764644,0.0225637852988906,1.0113793103447992,0.0014629795472849,-0.6386206534307348,0.0003081194146482
3SGB,A194M,0.5218390804597659,0.1789501982975803,-0.3316222733741304,0.0116527201022889,1.1403448275862125,0.0,0.179971628898282,0.0,0.3033333333333475,0.1397961069298599,-0.3417940349943077,0.1005883640511351
3SGB,A194N,1.188965517241385,0.1770429140647197,0.6714845562126764,0.0132537957177033,0.5527586206895994,0.0,0.1651425448691388,0.0,0.023793103448262,0.0,-0.5906107213634945,6.327007311595482e-08
3SGB,A194P,5.452413793103413,0.0,1.3309752696360695,0.0,5.094482758620651,0.0,0.929060451390044,0.0,5.140344827586182,0.0,0.4602821147109195,5.551115123125783e-17
3SGB,A194Q,0.6627586206896378,0.1838477631085162,0.131010103637086,0.009713421947812,0.849770114942506,0.0008127664151377,0.1428778667958999,0.0568299376611822,0.464137931034484,0.0,0.0011108916569303,6.327007312495014e-08
3SGB,A194R,1.4264367816091787,0.0001625532830274,1.1658432662717009,0.0059211163400902,0.2272413793103028,2.775557561562892e-17,0.3869149491287834,5.551115123125783e-17,-0.3213793103448332,0.0004876598490826,0.0957641752450598,0.000767618906669
3SGB,A194S,1.2589655172413503,0.1794588244666616,1.646825470909648,0.0101917460698684,1.1693103448275342,0.0,1.3337156562242616,2.220446049250313e-16,0.709310344827592,1.1102230246251563e-16,1.2159140684643874,0.0
3SGB,A194T,0.9544827586206998,0.0,0.9477421066580504,0.0,0.8048275862068389,0.0,0.4657238265281978,0.0,1.3206896551723888,0.0,1.1031344327884969,0.0
3SGB,A194V,-0.0620689655172633,0.1804835623820949,-0.562191543919402,0.0096187663720961,-0.1548275862069204,0.0,-0.9173878392302554,1.1102230246251563e-16,0.5289655172414157,0.0,-0.0347467343178438,6.32700731257679e-08
3SGB,A194W,0.8749425287356153,0.2441766209574971,0.0713280944213348,0.5180929342440771,-0.0951724137931266,0.1097465823003051,-0.9815583568791972,0.1307596883547097,-1.1629885057471194,0.2442541987793937,-2.085496827168268,0.295650271037036
3SGB,A194Y,-0.5351724137930715,0.0,-0.5036693015227716,0.0,-1.2336781609195604,0.0008127664151747,-1.4019473279247396,0.0172857853878725,-1.842528735632181,0.0005860941969867,-1.5146968441243338,0.0049084039706247
3SGB,E198=,-5.2273000742767785e-14,0.1753949923908621,,,0.0,0.0,-0.2711350215670414,0.0,0.0,0.0,-0.3286479476371918,0.0012165137038982
3SGB,E198A,0.3367816091953312,0.0,-0.7529688482710016,0.0,-0.0668965517241502,0.0029259590945697,-1.8064146804678245,0.0012876405658083,0.2420689655172407,0.0,-0.752950324447362,3.506944646566028e-09
3SGB,E198C,0.1960919540229513,0.0,-1.278428044029614,0.0021139687302405,0.2872413793103476,0.0052748477726548,-1.821703297592262,0.0031464417742685,0.1541379310344445,0.0,-1.2141395324179345,0.0
3SGB,E198D,-0.1849425287356757,2.775557561562892e-17,-0.0667856378679281,0.0,0.1052873563218321,0.0018101167526401,-0.2891492695841052,0.0032661080510838,0.5124137931034056,0.0,-0.2532539702878207,4.1506089434582716e-09
3SGB,E198F,-0.3949425287356493,0.0,-0.963016078501055,0.0,-0.2322988505746817,0.0072020460679541,-1.9897762500292089,0.0049040217562435,-0.5737931034482715,0.0,-1.0701552523140232,0.0
3SGB,E198G,1.7005747126436603,0.0004876598490826,0.1629969392487688,0.0049795557217069,1.94931034482762,0.1536128524646534,-0.1823223042125501,0.1656204398520805,1.603448275862022,2.220446049250313e-16,0.1810519502989086,2.775557561562892e-17
3SGB,E198H,0.3702298850574717,0.0,-0.2602040806418856,0.0,0.3806896551724282,0.0004876598490826,-0.8069330056197037,0.0035921173261382,0.2141379310344369,0.0,-0.299690922766425,0.0
3SGB,E198I,-1.1329885057471492,0.00357617222668,-1.7201793458639258,0.0015156802285801,-0.575977011494223,0.0050391517740017,-1.991183068080553,0.0287545790929742,-1.1055172413793557,0.0,-1.6708482970895195,7.172104319765745e-07
3SGB,E198K,0.2409195402298855,0.0,-0.538070008456951,0.0,1.1058620689655545,0.0,-0.409081512761163,5.551115123125783e-17,0.1531034482758482,0.0,-0.5600612479682648,0.0069933892578494
3SGB,E198L,-1.2321839080460324,0.0,-1.7320610386456072,0.0,-0.6921839080459695,0.0013004262642572,-1.925856354639864,0.0041028402974561,-1.155747126436789,0.0032510656606248,-1.576851955212036,0.0010616233309443
3SGB,E198M,-1.0955172413793568,0.002113192679395,-2.121160498633548,0.0043541353319816,-0.5148275862068752,0.0,-2.0731261627594417,0.0,-1.1220689655172873,0.0,-2.023639994915968,0.0
3SGB,E198N,0.7060919540229658,0.0,-0.6405906494022271,0.0,1.1581609195402325,0.0211319267940984,-0.7039626510971505,0.0572149628072083,0.8158620689655122,1.1102230246251563e-16,-0.309367455322915,0.0
3SGB,E198P,-0.8328735632184016,1.1102230246251563e-16,-0.7854910815184479,0.0,-0.4865517241379249,0.0024382992454501,-1.5777508082435647,0.0073937438258628,-1.1324137931034848,0.0,-0.8421320862464262,6.195565262913217e-08
3SGB,E198Q,-0.4604597701149784,5.551115123125783e-17,-0.6818983281798333,1.1102230246251563e-16,0.1331034482758769,0.2450232341139274,-0.8600936116870449,0.0866363754979057,-0.6703448275861931,0.0,-0.7290482370130403,0.0
3SGB,E198R,0.1636781609194854,0.0078834152641125,-0.9115828141074384,0.0412538930753336,0.7578160919540315,0.1050399894909386,-0.9879372692999882,0.1005067284833246,0.0957471264367651,0.0162553283031242,-0.8737164476597749,0.0188462618345627
3SGB,E198S,0.3809195402298679,0.0,-0.2915164280590222,0.0,0.8019540229885161,0.0150631734399481,-0.3467748221492028,0.1123531516589597,0.1895402298850445,0.0476281119281798,-0.2401212829778452,0.0174105679609528
3SGB,E198T,0.1988505747126196,2.775557561562892e-17,-0.8544582854255293,1.1102230246251563e-16,1.4444827586207163,0.0570562023439993,-0.5998209796801861,0.0053512542852936,0.3862068965516865,0.0,-0.7421978074195726,0.0
3SGB,E198V,-0.2797701149426036,0.0,-1.3032580857197744,0.0,-0.5112643678160765,0.0001625532830275,-1.9011257485226447,0.0052526411783575,-0.5162068965517486,0.0,-0.997759934327311,0.0
3SGB,E198W,-0.1711494252874123,0.0,-1.510089314086709,0.0,0.5964367816092043,0.0295967525793977,-1.8745972682449967,0.1965304325299379,-0.1436781609195664,0.0801041401711173,-1.617678445850497,0.176995928509247
3SGB,E198Y,-0.5995402298850977,0.0281442596744433,-0.8042320995601303,0.054547575500128,-0.2727586206896344,0.0,-1.7895102993830294,0.0,-0.7182758620689943,0.0313786787861124,-0.9690331618923728,0.02139731039142
3SGB,G211=,0.0,0.0053642583400199,,,0.0,0.0,0.1082740349603886,0.0,0.0,0.0,-0.1019667971533489,6.727845867516253e-08
3SGB,G211A,1.2743678160919527,0.1875560602325586,0.3706406157324709,0.0034541705994704,1.0744827586206849,0.0,0.4730641351304633,0.0,1.2586206896551253,0.0,0.3051651501698808,0.0
3SGB,G211C,2.2758620689655378,0.0029259590945698,0.4538306109771451,0.1591196240265148,1.972873563218416,0.067135096276578,0.6841475611059158,0.1785899611324346,2.1741379310344264,0.0,0.6285179344849737,0.0
3SGB,G211D,1.663448275862093,0.1543736786486946,1.2862919758540503,0.0315754606209143,1.6788505747126692,0.0884832035776561,1.4301655274551657,0.2258065151957096,1.7918390804597373,0.0008127664151376,1.2810502377416777,0.0014118885421287
3SGB,G211E,1.2793103448275729,0.003594596729004,1.038518290170006,0.0125102830761188,1.0798850574712884,0.0306674765958251,0.888195451345105,0.1743108733714113,1.1386206896551403,0.0,0.79082587379154,1.1102230246251563e-16
3SGB,G211F,0.2266666666666905,0.0161795644641241,0.3631029496538978,0.0029626937837585,0.0471264367815924,0.0328357631723405,-0.7798497906979124,0.048229925861307,0.1419540229884681,0.000905058376325,-0.8660651928225783,0.0034416010728612
3SGB,G211H,0.885172413793106,0.0068330408955023,0.7995169506484777,0.0125127091764349,0.5983908045977162,0.0015506594900209,0.612019345323641,0.0070636706020988,0.811149425287332,0.0027634058115422,0.1111246135980408,0.0040238902868217
3SGB,G211I,3.099540229885072,0.1965007663997068,1.4111384222743493,0.1281394302982012,8.290344827586232,3.5233424097053767,5.721622933593861,2.920723117987408,3.447931034482688,4.440892098500626e-16,1.643719595589934,0.0
3SGB,G211K,1.3717241379310312,0.0524115244518416,0.1812948971417103,0.0629582102800897,1.098505747126465,0.0607792789996126,0.3667063180235648,0.026895560379707,1.2041379310344436,0.0021989800540113,0.1368315403415547,0.0022787269717793
3SGB,G211L,0.9433333333333458,0.0487410536997261,-0.1574603581675494,0.0408032063553033,0.5277011494253275,0.0017880861133399,-0.0116768256652093,0.0014836580029332,0.9462068965516948,0.0023045905351533,-0.2355903534782879,0.0012490464083924
3SGB,G211M,1.7773563218390769,0.1939360812061839,1.2780288063148528,0.0247397398331097,1.425862068965514,0.0009753196981652,1.151286799240957,0.0105499941110155,1.6526436781608853,0.1100946637435409,1.0806918288524987,0.1517148274618238
3SGB,G211N,1.06919540229884,0.19808563254992,0.4002399762444138,0.0117854756435921,0.6906896551723894,1.1102230246251563e-16,0.0126978921889923,0.0,1.0904597701148997,0.0178808611334366,0.0396342981407385,0.0923058327651609
3SGB,G211P,1.0081609195402512,0.1922254945930986,1.0331889713307678,0.0111378409832458,0.8527586206896401,0.0,0.8412747220396294,0.0,1.0924137931034112,0.0,0.670002205192759,5.9146371291820553e-08
3SGB,G211Q,0.9680459770114972,0.0001625532830275,0.7845239904667188,0.0005942595803877,0.9247126436781432,0.0027634058115422,0.9384002004814084,0.0013084323221699,0.8506896551723693,0.0,0.5927539436796561,0.0
3SGB,G211R,1.3419540229885267,0.3442033813942541,0.3164139407470785,0.0595113728153631,0.5932183908046044,0.0007085533336578,0.2182330784414742,0.006050139778198,1.2542528735631702,0.0214373208770176,0.1605786901045733,0.0427284257236653
3SGB,G211S,1.432298850574714,0.1918128739770508,0.931272985671575,0.0126760088380346,1.4575862068965826,0.0,1.0555087954986089,0.0,1.4851724137930309,0.0,0.8270732973068303,0.0
3SGB,G211T,1.8209195402298963,0.2483668947626647,0.7801583728026648,0.0152418459543149,1.8065517241379423,0.0,0.8288557830104734,0.0,1.8510344827586,0.0,0.5715877857740495,5.9146408293666174e-08
3SGB,G211V,3.082988505747114,0.1908427464979382,2.155840082676427,0.0176388197314076,2.9013793103448235,4.440892098500626e-16,2.1975141062441628,0.0,3.1631034482758627,0.0,2.221711602101252,0.0
3SGB,G211W,0.625977011494269,0.1434538939365417,0.0099663318793454,0.057924398817291,1.722183908045997,0.0569792734311352,0.6343881188069447,0.6300372123615957,1.724137931034457,0.0004876598491195,0.2612641426453697,0.0296335246614945
3SGB,G211Y,-0.0322988505747067,0.0170572543903162,-0.5170024086856003,0.0160629844593488,-0.1118390804597651,0.0536960023513233,-0.7269961723257219,0.0452976844027324,-0.092758620689657,0.0,-0.7167484708052195,6.327007311595482e-08
3SGB,K192=,9.251858538542969e-18,0.1924599980228349,,,0.0,0.0,0.0313200640176813,0.0,-2.6127248512845352e-14,0.2167652143335513,-0.1876609182185891,0.0624218825432348
3SGB,K192A,1.804942528735629,0.0004876598490827,0.5922055037265782,5.859912403353532e-05,1.4358620689655128,0.0,0.5784122882185189,0.0,0.5686206896551336,0.0,-0.3368946422092292,5.551115123125783e-17
3SGB,K192C,1.653448275862094,0.0859906867236048,0.4701684957298646,0.036341286206075,1.3186206896551962,0.0,0.3293327700274356,0.0,0.4820689655172107,5.551115123125783e-17,-0.5954766765327658,6.327011006546405e-08
3SGB,K192D,4.2706896551724105,0.0217548284094254,1.0226914882170195,0.0324638541255311,3.888275862068989,0.0,0.9549357553382364,0.0,2.438275862068936,0.0,-0.1404705570368982,0.0
3SGB,K192E,2.835287356321829,0.1238659216562743,0.7438503099470397,0.0402360999935848,2.426551724137943,0.0,0.3551196180254026,0.0,1.441379310344771,2.220446049250313e-16,-0.3645378237142094,5.551115123125783e-17
3SGB,K192F,0.397011494252894,0.0018462503912789,-0.0556575196814547,0.0040720502703437,-0.0717241379309849,0.0,-0.0725282706587379,0.0,-1.2579310344828063,0.0,-0.7560930084002195,6.327007311595482e-08
3SGB,K192G,4.07471264367814,0.0009050583763383,0.7821372042280145,0.0012453889655149,3.568620689655228,0.0,0.7596851805705432,0.0,2.733793103448236,0.0,-0.1015010420681015,0.0
3SGB,K192H,2.1519540229885035,0.0178609002709319,0.2792900766271957,0.0252214373370945,1.8451724137931425,0.0,0.3525052925579859,0.0,0.8396551724137743,0.0,-0.4779071551562167,6.327007311595482e-08
3SGB,K192I,-0.4109195402298642,0.0273089515492931,-0.413024033650303,0.032735584300031,-0.6848275862068539,0.0,-0.3788665917118672,0.0,-1.5531034482759078,0.0,-1.1787177930545238,0.0
3SGB,K192L,-0.5920689655172491,0.1216911919639504,-0.2842788444781004,0.0365015236716411,-0.876896551724101,0.0,-0.3052872727009563,0.0,-1.0962068965517542,0.0,-0.6596258152466749,6.327011011780043e-08
3SGB,K192M,0.403563218390827,0.1326434789536194,0.2435193119463972,0.0139232630056421,0.1451724137931203,0.0,0.2485227624223908,0.0,-0.7164367816092154,0.0013004262642573,-0.5271159145358614,0.0029235721403909
3SGB,K192N,2.068160919540249,0.0262089130097667,0.6615042354839726,0.034457831343611,1.6444827586206916,0.0,0.685036182243619,1.1102230246251563e-16,0.7389655172413893,1.1102230246251563e-16,-0.2754279682817626,0.0
3SGB,K192P,4.725747126436811,0.0130377461502926,0.6474280791044241,0.0102640561893905,4.691034482758635,0.0,0.4310571529463781,0.0,3.816666666666659,0.0003251065660551,-0.4172835306906501,0.0006776254415847
3SGB,K192Q,0.3845977011494257,0.1348703521557043,0.309098262844093,0.039240248061142,0.1189655172413887,0.0,0.2049847432891542,2.775557561562892e-17,-0.6806896551724689,1.1102230246251563e-16,-0.6632797459554177,6.327003616644566e-08
3SGB,K192R,0.6104597701149598,0.0287719310965409,0.3672111111531267,0.0370792278433606,0.5466666666666765,0.0281217179644307,0.3021759990701474,0.1083743357437901,-1.1568965517241443,0.0,-1.2888200295715095,0.0
3SGB,K192S,2.304482758620713,0.0140671999493164,0.718192218526085,0.0226419604341826,1.9227586206896623,2.220446049250313e-16,0.7292753386015005,0.0,0.9824137931034252,1.1102230246251563e-16,-0.230950953831487,6.327007311595482e-08
3SGB,K192T,1.2890804597701315,0.1209425920949309,0.4545203253699312,0.0423123748171026,1.0251724137931668,0.0,0.5034134444809784,0.0,0.1996551724137761,0.0,-0.4267544795544151,6.327007311595482e-08
3SGB,K192V,-0.4374712643678207,0.114117961929915,0.3667590178541616,0.0203209693429163,-0.5087356321839,0.0011378729812297,0.2957926647910876,0.0090442063490255,-1.4200000000000574,2.220446049250313e-16,-1.0591926888443972,0.0
3SGB,K192W,1.1677011494252734,0.095290198645954,0.4682724368458053,0.0114994797688926,0.2020689655172457,0.0,0.3143285208510986,0.0,-1.4996551724138485,0.0,-0.8164504569601805,6.327007311595482e-08
3SGB,K192Y,1.0839080459769928,0.0297805422647249,-0.0381867650991347,0.0338865900589811,0.3851724137931425,0.3013737867402042,-0.1187163489879268,0.2331184863076584,-0.7005747126437075,0.0742057072359616,-0.9168309562091546,0.027577527374884
3SGB,L197=,0.0,0.0,,,-2.613491020819758e-14,0.0004876598491195,-0.220235683368615,0.0020422456910469,0.0,0.0,-0.0932424732036452,0.0
3SGB,L197A,2.842068965517307,0.0,2.0819607998186225,0.0,2.929655172413748,0.0,2.0086065252125365,0.0,2.799999999999963,4.440892098500626e-16,1.8759307026246088,0.0
3SGB,L197C,2.682528735632232,0.1157379375183481,1.939771422735144,0.0447619632381578,2.6955172413792865,0.0014629795472848,1.6904101010934145,0.0001802029397415,2.571379310344786,0.0,1.7848069697816002,0.0
3SGB,L197D,3.762413793103468,4.440892098500626e-16,3.9662749368255454,0.0,3.64218390804594,0.0003251065660551,3.894631278514221,0.0037894764608539,3.594482758620656,0.1155753842353205,3.8021241945247226,0.0508767547270666
3SGB,L197E,3.93172413793105,4.440892098500626e-16,3.369353453506628,4.440892098500626e-16,4.1365517241378855,0.0,3.5488439902031463,0.0,3.823448275862057,0.0,3.1340009923761065,4.440892098500626e-16
3SGB,L197F,-1.4262068965517127,2.220446049250313e-16,-1.6754745203071126,0.0,-1.1341379310345567,0.0,-1.8042650754561909,2.220446049250313e-16,-1.4848275862069105,0.0,-1.9345490639428704,6.935219234789138e-08
3SGB,L197G,4.85137931034484,0.0765625963077853,3.570187184010953,0.0045520884924853,4.672758620689631,0.0,3.7621684613964135,0.0,4.503103448275851,0.0,3.602595682540068,7.562277244680094e-08
3SGB,L197H,1.1244827586207045,0.0004876598491195,1.0389689017912636,0.0035400349473731,1.5214942528735464,0.0013004262642573,1.167688758452482,9.322880130408153e-06,1.0241379310344922,0.0,0.6758635749909069,0.0
3SGB,L197I,1.77551724137935,0.0,0.5182242465127337,0.0,1.8041379310344727,0.0,0.533534952990093,0.0315817227757987,1.595632183908027,0.0004300755616879,0.3533546369442973,0.0015583282944124
3SGB,L197K,2.5062068965517343,0.0,2.332011864580155,0.0032703966432542,2.530344827586195,0.0,2.2681917403872767,0.0,2.5193103448276,0.0,2.239309037124556,0.0
3SGB,L197M,0.6724137931034639,0.0,0.0562807141009529,0.0,1.1735632183907825,0.0023443767878392,0.3174075221907373,0.0378831512560856,0.7399999999999856,0.0,0.2314539573061164,0.0
3SGB,L197N,2.0872413793103832,0.0,2.522362579908735,0.0,1.9131034482758629,2.220446049250313e-16,2.127658583495202,0.0015257511454311,1.8400000000000043,0.0,2.1332355730593355,0.0
3SGB,L197P,5.32689655172417,0.0,4.961995926617827,0.0,8.289310344827582,0.0,6.235305226677791,0.0,6.647586206896559,0.0,6.22513842730886,7.995419132752205e-08
3SGB,L197Q,2.2431034482759,0.0,2.378886108561676,0.0,2.181149425287317,0.0006502131321471,1.7698606261083587,0.0022177752198243,1.8000000000000094,0.0,1.3610145041010762,3.083564033776838e-09
3SGB,L197R,2.644827586206922,0.0,2.429387820937273,0.0,1.9144827586206576,0.0,1.50535386353983,0.0,2.756206896551703,0.0,2.523960351953942,6.450447441632125e-08
3SGB,L197S,3.8268965517242015,0.0,3.6444998528986616,0.0,3.861839080459765,0.0030885123775972,3.5330219804923586,0.000829752300117,3.77655172413793,4.440892098500626e-16,3.469379013674459,7.562277244680094e-08
3SGB,L197T,2.898965517241432,0.0,2.8620292848604394,0.0,2.9996551724137386,0.0,2.8909830758578305,0.0,2.74620689655173,0.1160630440844033,2.560937505974505,0.0389538502430039
3SGB,L197V,1.626781609195457,0.0128417093594718,0.8161960760658703,0.0136917473993815,1.501494252873523,0.0034749922891719,0.7297332181800206,0.0073966436695199,1.421034482758601,0.0011262021805953,0.5521957687071973,0.0039673989913457
3SGB,L197W,-0.9189655172413668,0.0,-1.8315498034504063,0.0,-0.7193103448275906,0.0,-1.912747261221896,2.220446049250313e-16,-1.0396551724138277,0.0,-2.0012480914800204,0.0
3SGB,L197Y,-0.9279310344827432,0.0509762015771064,-1.0470230553056386,0.0979510257584211,-0.8113793103448762,0.0034136189436524,-1.1563468178744305,0.0016610396989874,-0.9479310344827668,0.0,-1.1506308074420817,6.792788873100207e-08
3SGB,N207=,0.0,0.0,,,0.0,0.0,0.0004183004644126,5.421010862427522e-20,0.0,0.0,0.0006932852217436,0.0
3SGB,N207S,1.051724137931019,0.0,0.0008680042418714,0.0,1.0989655172414226,0.0,0.0002564191805535,0.0,1.0072413793103618,0.0,0.0014561033648711,6.327011008529464e-08
3SGB,N215=,0.0,0.365744886820628,,,0.0,0.0,0.1308181596108044,0.0,0.0,0.0,-0.0971764037963739,0.0
3SGB,N215A,0.5534482758620752,0.0,0.3388647171301931,0.0,-0.2358620689655065,2.775557561562892e-17,0.2468123703287237,0.0,0.1106896551723836,1.3877787807814457e-17,0.0517866554497785,6.327011008509019e-08
3SGB,N215C,0.7396551724137347,0.3506274314986967,0.2343182485126545,0.0377799848612612,0.3913793103448245,0.0,0.1949540421714479,0.0,0.709310344827592,1.1102230246251563e-16,-0.0088192566328149,0.0
3SGB,N215D,0.777241379310286,0.3686708459151978,0.326711218295196,0.0288724290112222,0.3375862068965662,5.551115123125783e-17,0.3972016939928835,0.0,0.5913793103447994,0.0,0.1672978816376881,0.0
3SGB,N215E,-0.8422988505747621,0.1441850369413843,0.1465928290156563,0.0417857026824153,-0.8858620689655035,0.0,0.2966243752754947,0.0,-0.7258620689655236,1.1102230246251563e-16,-0.1099541173530739,1.3877787807814457e-17
3SGB,N215F,-1.5862068965517189,0.3813500019916421,-1.525781502184025,0.0349930179210271,-2.573793103448256,0.0,-1.303975771237486,0.0,-1.7575862068965449,0.0,-1.2528410159745162,6.32700730636184e-08
3SGB,N215G,1.462758620689642,0.3193320664889078,0.4434257644262007,0.0458627419104065,1.0744827586206849,0.0,0.3772001025882234,0.0,1.4393103448275788,0.0,0.1714980674127292,6.327007311595482e-08
3SGB,N215H,-0.1413793103448558,0.0,-0.3237538453241729,0.0,-1.0313793103448226,0.0,-0.2844653288674447,0.0,-0.878620689655173,0.0,-0.4501961761485845,6.327007311595482e-08
3SGB,N215I,-1.2132183908046312,0.3151908157978784,0.0288644857144537,0.0754229873888402,-1.5096551724137426,0.0024382992454871,-0.0500633695481746,0.0028987670763199,-1.078620689655148,0.0,-0.1587114414234026,0.0
3SGB,N215K,0.5303448275861845,0.48263479528555,0.5475124102469281,0.1852326147617797,-0.5255172413792715,0.0,0.1200480779057843,0.0,0.4927586206896069,0.0,0.45947316094945,0.0
3SGB,N215L,-0.991149425287388,0.3253114405608392,-0.0982035198165866,0.0354969537904904,-1.060804597701102,0.0240578858886681,0.1132740138623323,0.2597018547657077,-0.8410344827586477,0.0,-0.2753936749946535,0.0
3SGB,N215M,-0.6559770114942914,0.3571295628199832,0.059430998344919,0.0546436761012625,-1.2010344827586026,0.0,-0.3627352963059334,0.0,-0.6710344827586168,0.1058225617995182,-0.3251446994485293,0.0635527091779916
3SGB,N215P,4.236436781609167,0.178630304923246,1.3362545596327562,0.0688189606963742,4.027931034482773,0.0,0.6876997471785029,0.0,4.244827586206878,0.000975319698165,1.3923904296119476,0.0006806845129575
3SGB,N215Q,-0.443678160919581,0.3921231306748414,0.117456194905169,0.0490502481380876,-1.304367816091923,0.000325106566055,-0.1281323394814744,0.0003405029783397,-0.8500000000000502,0.0,-0.2193048345285812,6.327011007854813e-08
3SGB,N215R,-0.6311494252873807,0.0084527707176171,-0.1783465833232342,0.0013954985609264,-0.6934482758620577,0.0,-0.4071813323181341,0.0,-0.192068965517247,0.0,-0.384100566959895,0.0
3SGB,N215S,0.910689655172388,0.3355308853589028,0.5513004781869575,0.1030681021650007,0.3944827586206915,0.0,0.4087516887162518,5.551115123125783e-17,0.7596551724137844,1.1102230246251563e-16,0.1884513039114619,6.327007312903894e-08
3SGB,N215T,-0.0521839080459975,0.0006502131321101,0.2188323328977245,0.0044552231608475,-0.1473563218390719,0.0011378729812297,0.1998898740384249,4.161121379393408e-05,0.2596551724137687,0.0,-0.0071353606865587,6.327007312495014e-08
3SGB,N215V,-1.0381609195402737,0.3357820874500823,-0.0584167734170697,0.0404269896455797,-1.2467816091953738,0.0011378729812297,-0.0599323095255793,0.000228748178543,-0.885172413793106,0.0,-0.2590209674502242,0.0
3SGB,N215W,-0.9048275862069308,0.3808623421425595,-1.3091397539353928,0.2356362144649701,-2.4437931034482463,0.0009753196982022,-1.4501412003198244,0.0001338733101177,-1.1758620689655457,0.0,-0.7198633425910289,0.0
3SGB,N215Y,-2.1983908045976985,0.1739320128435773,-1.5636353337453297,0.011028942887533,-2.337241379310352,0.0,-1.111850042216835,0.0,-1.5648275862069003,0.0,-0.8480744320782811,6.327011006546405e-08
3SGB,P193=,0.0,0.0,,,0.0,0.0,-0.0779789462218763,0.0,0.0,0.0,-0.0058873613923309,6.327011008549904e-08
3SGB,P193A,0.5106896551724119,0.0,0.0613639505167909,0.0,0.5286206896551385,0.0,-0.0735007790132746,0.0,0.4806896551724156,5.551115123125783e-17,-0.1774768786715909,6.327007312903894e-08
3SGB,P193C,0.7372413793103173,0.0,-0.2625677683139155,0.0,0.8489655172413756,0.0,-0.0943258891775179,0.0,0.958620689655163,0.0,-0.113416970489511,0.0
3SGB,P193D,0.0972413793103191,0.0,0.212433643955435,0.0,0.1296551724137849,0.0,0.0395978095520902,0.0,0.143793103448247,0.0,0.1847899042814819,2.775557561562892e-17
3SGB,P193E,-0.2379310344827774,0.0,0.4709011734594869,5.551115123125783e-17,-0.2544827586207091,0.0,0.1740051885879219,0.0,-0.2468965517241799,2.775557561562892e-17,0.3285271229548466,6.327007314212303e-08
3SGB,P193F,-1.0583908045976846,0.0001625532830274,-1.8689614970853183,0.0009619846414596,1.0286206896551542,0.0,-0.1008540907357342,0.0,-0.4686206896551723,0.0029259590945697,-1.4470021917629738,0.0012825461953091
3SGB,P193G,1.1496551724138138,0.0,0.2378605670410566,2.775557561562892e-17,1.1513793103448076,0.0,0.2463330269472016,0.0,1.1834482758620746,0.0,0.2056320368769618,0.0
3SGB,P193H,0.570000000000007,0.0,0.709504046906361,0.0,0.5489655172413348,0.0,0.6945841438261503,1.1102230246251563e-16,0.5689655172413323,0.0,0.5589995311661683,6.327003616644566e-08
3SGB,P193I,0.1493103448275837,0.0,-0.5241350362801565,0.0,0.3506896551723535,0.0,-0.313326184332568,0.0,0.364827586206894,5.551115123125783e-17,-0.3509826792056347,5.551115123125783e-17
3SGB,P193K,0.1672413793103103,0.0,0.2500860159835642,0.0,0.1782758620689053,0.0,-0.0447115953848596,0.0,0.1689655172413563,0.003901278792735,0.1442003776723684,0.0054081415912076
3SGB,P193L,-0.2699999999999661,0.0,-0.6686762594410446,1.1102230246251563e-16,0.192068965517247,0.0,-0.3667914050329116,5.551115123125783e-17,0.1620689655172507,0.0,-0.3505885089128597,6.327011009163222e-08
3SGB,P193M,-0.1879310344827837,0.0,-1.036398448561848,0.0,0.3893103448275536,0.0,-0.4222284830494369,0.0,0.6699999999999943,1.1102230246251563e-16,-0.1197752193376863,0.0
3SGB,P193N,0.444827586206884,0.0,0.2131634293327963,0.0,0.4368965517240777,0.0,0.0951583141442495,0.0,0.4686206896551461,0.0,0.1430526095178908,0.0
3SGB,P193Q,0.1758620689655141,0.0,0.292055668529852,0.0,0.1641379310344432,0.0,0.2565594671791038,0.0,-0.0520689655172645,0.0,0.0788512850425016,6.327003615990359e-08
3SGB,P193R,0.3406896551724332,0.0,0.1036410375155387,0.0,0.4382758620689511,0.0,-0.2054564964565731,0.0,0.4958620689654739,0.0,0.2030941501824411,0.0
3SGB,P193S,-0.0506896551723912,0.0,0.3753064050267218,0.0,-0.0420689655172658,6.938893903907228e-18,0.3539798245776245,5.551115123125783e-17,0.1055172413792457,0.0,0.4451264353571693,0.0
3SGB,P193T,0.2937931034483066,0.0,0.3539134513406961,5.551115123125783e-17,0.2072413793103053,0.0,0.1671444228313624,2.775557561562892e-17,0.3137931034482257,0.0,0.252192023761606,6.327011009163222e-08
3SGB,P193V,0.192068965517247,0.0,-0.4647023665889437,5.551115123125783e-17,0.3382758620689636,0.0,-0.38435993073696,0.0,0.3655172413792915,0.0,-0.3667337004883942,0.0
3SGB,P193W,0.143793103448247,0.0,-1.22911975899687,0.0,-0.6558620689655323,0.0,-2.05599167858037,0.0255601206269539,-0.6333333333333585,0.0008127664151747,-1.846204097146857,0.0012537628588917
3SGB,P193Y,-1.1675862068965406,0.0,-1.750926913753433,0.0,0.7917241379309731,0.0,0.4212239490944457,5.551115123125783e-17,-0.5400000000000107,0.0,-1.2569707056722652,6.32700730636184e-08
3SGB,R200=,0.0,0.1905292986944191,,,0.0,0.0,-0.1475250694006169,0.0,0.0,0.0,0.0753072127072143,0.0
3SGB,R200A,0.8375862068965819,0.2169405567869298,0.4447097647601722,0.031307416912435,1.0111494252872808,0.0047140452079096,0.093454089779115,0.001764110737566,0.9734482758620224,0.0,0.4841200962314047,0.0
3SGB,R200C,1.022873563218404,0.1914877674109957,0.2882031071926419,0.0347239635400472,0.968275862068963,0.0,0.1061300462554456,1.3877787807814457e-17,1.0013793103448263,0.0019708538160452,0.5137560430061079,0.0006594704021005
3SGB,R200D,0.9160919540230178,0.0,0.8361118926834402,1.1102230246251563e-16,1.4397701149424842,0.0856655801575498,0.5220507484864488,0.0928358720434608,1.362068965517257,0.0,0.9113315190722262,7.757342805019727e-08
3SGB,R200E,1.7099999999999946,0.0001625532830275,0.5835751133916075,0.0034011229713192,1.7147126436781226,0.0095242907981162,0.3493298353532606,0.0041916026867347,1.4241379310344942,0.054705640428832,0.5586020397365362,0.0250715228548565
3SGB,R200F,0.3512643678160965,0.0331608697384325,0.2129858604695627,0.001538148275695,0.631609195402234,0.0016255328303124,-0.0951642459250152,0.0001733459855568,0.676896551724126,0.0,0.2348680752835866,2.775557561562892e-17
3SGB,R200G,2.7613793103448665,0.0040638320757626,0.5852660834473724,0.0015635518332983,2.7789655172413688,0.0,0.1608749151291939,0.0,2.5989655172413912,0.0,0.5479625939976578,0.0
3SGB,R200H,0.5703448275862318,0.1069796982282332,0.1068312570218845,0.1529736677292601,0.4906896551723883,0.0051685809553935,-0.4235975786331039,0.0340595908220066,0.4606896551724182,0.0,-0.0241903672664695,6.475772670561017e-08
3SGB,R200I,0.5008045977011722,0.1757200989569171,0.1276969238450947,0.0041926254505489,0.5341379310344753,0.0,-0.2951021813804534,0.0,0.4113793103448219,0.0,0.1075464943843646,6.359913100653123e-08
3SGB,R200K,0.5535632183908343,0.1914347715709375,0.0989366670933645,0.0064519883947657,0.9174712643678128,0.0016255328303124,-0.0698375330535134,0.0012015180164419,0.7906896551723769,0.0048765984909372,0.3779388243137402,0.0024973012850251
3SGB,R200L,0.6251724137931386,0.1905124477127934,0.1145993258332128,0.0045164023037478,0.7565517241379173,0.0,-0.2331337043300789,0.0,0.7268965517241197,0.0,0.0152140144866185,1.734723475976807e-18
3SGB,R200M,0.3357471264368134,0.184936492189842,-0.5428724267519635,0.0066005466258235,0.5562068965516652,0.0,-1.0313475589912835,0.0,0.2517241379310407,0.0,-0.5919326178030228,0.0
3SGB,R200N,0.502643678160925,0.2024035126332664,0.4940844678004794,0.0073648862957125,0.7320689655171794,1.1102230246251563e-16,0.1935512846411461,2.775557561562892e-17,0.5837931034482703,0.0,0.5937289522487311,8.055505540118652e-08
3SGB,R200P,4.550919540229894,0.0065969401619804,0.956247314199818,0.0170778502107032,4.973793103448268,0.0,0.5801545077960113,0.0334662073689147,4.450229885057483,0.0486034316263821,0.641218925868726,0.0268415590794728
3SGB,R200Q,0.4608045977011772,0.1947681393047798,-0.2629184204836005,0.0094170430821095,0.6855172413792513,1.1102230246251563e-16,-0.5909103122146018,0.0341416740075309,0.4051724137930878,5.551115123125783e-17,-0.2372154074157737,6.698004092302965e-08
3SGB,R200S,0.9747126436781892,0.1809437101382862,0.6136690399872329,0.0027657594977256,1.32999999999999,0.0,0.2786396482948585,0.0,1.1758620689655457,0.0,0.6795481611348366,0.0
3SGB,R200T,0.7004597701149745,0.1704495776709352,0.1749120170461015,0.0076199518038364,0.849655172413773,1.1102230246251563e-16,-0.2045899667430227,0.0,0.5921839080459559,0.0611200344198358,0.1213121976673852,0.0082085935830276
3SGB,R200V,0.1064367816092135,0.1239599618277786,0.1226907301891557,0.0393934093530135,0.1724137931034483,0.0,-0.277719597351914,0.0,0.1889655172413799,2.775557561562892e-17,0.1064451461158684,6.865123953138472e-08
3SGB,R200W,0.2283908045977365,0.1998430484696951,0.3007443010157355,0.0081630386541001,0.2195402298850146,0.0529953619619854,0.0721074322481446,0.0548301565743618,0.0980459770115017,0.026014620318971,0.3919572111792003,0.0258881339852975
3SGB,R200Y,0.3620689655172518,0.238846868644721,0.2683585035504035,0.0323094899844063,0.4333333333333051,0.002113192679432,-0.0068700339077481,0.005734635971373,0.4668965517241523,0.0136544757746465,0.2429527636637357,0.0430612487966141
3SGB,T196=,2.6134187406749262e-14,0.0190936113101914,,,0.0,0.0,-0.2109504380232779,2.775557561562892e-17,0.0,0.0,-0.0847180335568768,0.0
3SGB,T196A,1.46298850574716,0.1796215984101188,0.6203371843270591,0.0033381629754382,1.8975862068965272,0.0,0.7767718936791677,0.0,1.5744827586206742,0.0009753196982021,0.7370318522661125,0.001749314428843
3SGB,T196C,1.0362068965517357,0.0014629795472849,-0.3802009550473935,0.0050058492455748,1.482068965517242,0.0,-0.1880162607514241,0.0,1.2186206896551826,0.0009753196982022,-0.2081624538148431,0.0023326394401396
3SGB,T196D,1.9009195402299124,0.1802715908818363,2.0627865649741537,0.0093053676030731,2.817816091954061,0.388566410281234,2.283247534107533,0.166155375865514,2.366896551724149,0.0,2.1462194034533524,0.0
3SGB,T196E,1.5977011494253242,0.1771018578126392,1.2754320342015364,0.0094105430180144,2.142758620689661,0.0036817511213984,0.994794510643874,0.0352265386055977,1.6689655172413511,0.0,1.1279820545654071,0.0
3SGB,T196F,0.5545977011494566,0.1760180361649426,-0.0833443812657553,0.0397244968973944,1.10459770114944,0.2624468439218511,-0.1430848421881265,1.0177540443858084,0.6867816091953919,0.004226385358827,-0.1400436080945482,0.0073809624453433
3SGB,T196G,2.444712643678162,0.1584530181605737,1.8035583191875244,0.0815445193545778,2.725517241379309,0.0,1.621039003460455,0.0,2.922758620689694,4.440892098500626e-16,2.019830642124644,0.0
3SGB,T196H,1.2282758620690089,0.0004876598490826,0.9045202433878132,0.0001209883229891,1.4350574712643562,0.017393201284354,-0.1402639144516379,0.0289163590479135,1.0647126436781778,0.0130164484293334,0.5259352901203397,0.0037212906077549
3SGB,T196I,0.0166666666667168,0.1792962711836341,-0.6637993633793402,0.0044282713672348,1.12712643678164,0.0044546718103547,-0.7859647551173823,0.036853407021955,0.2108045977011563,0.002113192679432,-0.468865313005075,0.004759706545087
3SGB,T196K,0.5886206896551833,0.0014629795472849,-0.1468654422737979,0.0023788144050734,1.295057471264374,0.0051172021355414,-0.2681461190741305,0.0464775871594442,1.5817241379310307,0.0,0.987885059198744,7.15229468616766e-08
3SGB,T196L,-0.8108045977011334,0.0030105289318897,-1.4999787601223764,0.0044771915195423,-0.4725287356321435,0.1173634703486605,-1.5924985230448665,0.0808444745675662,-0.781379310344854,0.0,-1.3854779582966958,0.0
3SGB,T196M,0.2718390804597973,0.1672365998448226,-0.5405319010166708,0.0359137616530772,1.7986206896552146,0.0,0.064826135786388,0.0077017034052546,1.5072413793103774,0.0,0.3522827767131213,5.551115123125783e-17
3SGB,T196N,1.1862068965517432,0.0691222357281649,0.5142588299512963,0.1142718762476198,1.6080459770115214,0.005751722300317,0.6354038182416974,0.0177281790895911,1.428965517241381,0.0,0.6445834854130434,8.166279367936186e-08
3SGB,T196P,1.2122988505747416,0.1759653366698672,0.7374274235798604,0.0164196372285748,1.890574712643715,0.0019164749425806,0.6248363657507081,0.0143712362607835,1.5875862068965665,0.0,0.6342211231259987,0.0
3SGB,T196Q,0.6357471264368281,0.1758826522399447,0.1377813852397186,0.0002494713379413,1.3214942528735714,0.0879413261199724,0.1775399513617988,0.0280773593681919,0.926551724137896,0.0,0.2672738191440083,0.0017739225255101
3SGB,T196R,0.7389655172413893,1.1102230246251563e-16,0.3385992883452923,0.0,0.7988505747126751,0.0056893649061119,-0.4014447472684162,0.0055700291888958,0.9494252873563208,0.002113192679395,0.2243076289195331,0.0008596871261384
3SGB,T196S,1.2618390804598036,0.1795445714517911,1.476696791868165,0.0074851460877104,1.717586206896576,0.1989652184304106,1.2235157681225142,0.0209827742058984,1.5181609195402397,0.0013004262642203,1.5067291384444803,0.0007684884951841
3SGB,T196V,0.2972413793103724,0.1448349751809811,-0.2825305773098048,0.0214480086139674,1.276321839080491,0.0013888558590377,-0.7207807398219757,0.044368005117182,0.4934482758620828,0.0,-0.199922416313633,0.0
3SGB,T196W,-0.0351724137930819,0.2143302484723794,-0.2264078579569338,0.0062304945290874,0.7842528735632551,0.0025547253759677,-0.2562814632762675,0.0150925054475794,0.1083908045977254,0.000325106566055,-0.2169578956541149,0.0040362791852052
3SGB,T196Y,0.409655172413802,0.1804341441648269,-0.0078762009561301,0.0147545242569032,1.0951724137930796,0.0,0.6971197035214499,0.0379590035663447,0.6837931034482838,0.0019506393964044,0.14897329244837,0.0024765957240881
3SGB,Y199=,0.0,0.0,,,0.0,0.0,-0.1756801763775096,2.775557561562892e-17,0.0,0.0,-0.1206031684396868,6.028497147091505e-08
3SGB,Y199A,2.002298850574696,0.0208068202280434,0.3547853470770379,0.0029940475754115,1.9596551724137907,0.0,0.233385350702598,0.0,2.0639080459769743,0.0003251065660551,0.2628089051756234,0.0025667177659072
3SGB,Y199C,1.486551724137904,0.0,0.722129353970684,1.1102230246251563e-16,1.8282758620689337,2.220446049250313e-16,0.5486869293215164,0.0,1.94793103448272,2.220446049250313e-16,0.7892774366686792,0.0
3SGB,Y199D,1.511034482758616,0.1744080072487171,0.5810336810519591,0.0102189023168316,1.6686206896551523,0.0,0.3460469830887914,5.551115123125783e-17,1.7531034482758827,0.0,0.3718666614800351,7.266727588291947e-08
3SGB,Y199E,2.317356321839061,0.2520898513814235,1.3763592183005162,0.6081712055410375,1.8775862068965297,0.0,0.3995124740333722,0.0,2.4287356321838947,0.3585925423672312,0.8551331718281133,0.3808423081091142
3SGB,Y199F,-0.0711494252873726,0.0011378729812271,-0.2369131485838598,0.0030040339413642,-0.0375862068965515,0.0004876598491196,-0.2654953252587786,0.0012824857961795,-0.012758620689667,0.0,-0.1410447846851168,0.0
3SGB,Y199G,3.5271264367816264,0.1306377336988609,1.4050712498159106,0.0265160919190683,3.737241379310333,0.0,1.2180247736495764,0.0,3.85448275862065,0.0,1.2847286437576697,0.0
3SGB,Y199H,1.4689655172413765,2.220446049250313e-16,0.8047152650515429,0.0,1.477011494252863,0.0762458075796429,0.5230837811873322,0.1748717927834365,1.4320689655172485,0.0,0.6996769994074823,0.0
3SGB,Y199I,3.124252873563224,0.1979503241297847,1.603535486399036,0.1383089169500516,3.1044827586206654,0.0,1.648442388434746,0.0,1.779310344827536,0.0,1.3312542323495986,0.0
3SGB,Y199K,3.2175862068965184,0.0,1.9579290936488587,0.0,3.15482758620691,0.0453523659657571,1.655674354346865,0.1862414680405144,3.071724137931001,4.440892098500626e-16,1.793969311222711,2.220446049250313e-16
3SGB,Y199L,1.563103448275828,0.0,0.9294122170464608,0.0,1.2613793103447937,0.0,0.7184484635644729,1.1102230246251563e-16,1.3845977011493786,0.5674735110625809,0.6572787455842047,0.5088070740382258
3SGB,Y199M,1.2736781609195291,0.0242204391716588,0.1372193911903593,0.0007646756919461,1.244827586206862,0.0,0.0598004884062479,0.0,1.1428735632183888,0.0003251065660919,0.030941042314173,0.0002263664669478
3SGB,Y199N,1.7937931034482757,2.220446049250313e-16,0.9111772344110628,1.1102230246251563e-16,1.7500000000000158,0.0,0.7023955225448891,0.0,1.7358620689654751,0.0,0.7359122532614429,0.0
3SGB,Y199P,10.533678160919544,1.53287745898602,6.879079879711116,0.4975264555836799,11.522068965517237,0.0,6.870480500941519,0.0385204892379518,10.052758620689636,1.4698067851698535,6.7167496195989855,0.4463612186103871
3SGB,Y199Q,2.441034482758604,0.0,1.6094774895017163,0.0,2.409540229885053,0.012028942944334,1.4275489724684969,0.0109206016792651,2.387931034482743,0.0,1.4968488407867913,0.0
3SGB,Y199R,1.5268965517241762,0.0,0.3437782100065996,0.0,1.4393103448275788,0.0,0.1188205312845294,0.0,1.4472413793103067,0.0,0.2044033412873651,0.0
3SGB,Y199S,2.5651724137931304,0.0,1.4802140648377862,2.220446049250313e-16,2.504827586206861,0.0,1.3370046092663008,0.0,2.5551724137930534,0.0,1.4218381454642617,5.663765144546439e-08
3SGB,Y199T,2.21172413793103,0.0,1.757828183022741,0.0,2.566896551724124,0.0,1.531267581214142,2.220446049250313e-16,2.873103448275821,0.0,1.8046521382869536,2.220446049250313e-16
3SGB,Y199V,1.478850574712616,0.0206442669449788,0.8358888583671124,0.0030878458432253,1.9137931034482605,2.220446049250313e-16,0.6163787931776479,0.0,2.2462068965516884,0.0,1.0835580137802874,7.625131981499635e-08
3SGB,Y199W,-0.3220689655172307,0.0,-0.7086528953278378,1.1102230246251563e-16,-0.2034482758621191,0.0,-0.8033355770961909,0.0,-0.2658620689655028,0.0,-0.6255775894577574,0.0004755370267268
1OGA,A149=,-1.0452749776845849e-13,0.1539132393345173,,,0.0,0.001788086113266,0.0006607938925738,0.002139114868223,0.0,0.0,-0.3121758360687416,3.104674659648793e-12
1OGA,A149G,0.7305747126434423,0.0449462032186822,0.0777894405493351,0.0023664094762421,0.8317241379310203,0.0013004262642203,-0.0024938121752669,0.0003059356801209,0.9095402298851112,0.0017880861134138,-0.2490458834122312,0.0001045603749084
1OGA,A150=,-1.04539351712211e-13,0.0114516451672208,,,-1.0453964083279033e-13,0.0008127664151746,-0.0019223229987644,0.0005290442098982,-3.614007241618348e-20,0.0013888558590832,-0.3174073370849526,0.0021361084873834
1OGA,A150G,1.612528735631922,0.005908090701555,0.8217263676731651,0.0058244001713028,1.0454022988507088,0.0011378729811558,0.3344988524818892,0.0008703971851223,1.258965517241324,0.0306674765958621,0.4074825145354466,0.0395691902645223
1OGA,A158=,-1.0453964083279033e-13,0.005533978444758,,,0.0,0.0034058695149656,-0.4315957260381891,0.0020789454125135,3.136183442572123e-13,0.0196689472468135,-0.3213601052806782,0.0051483731319829
1OGA,A158G,1.172183908045909,0.0004876598490456,0.4793635780031597,0.0021537177284064,1.7693103448275895,0.000430075561646,0.3988262521559868,0.0028243599181979,1.4206896551725852,0.0174886483386775,0.0950490543223638,0.0052547699723487
1OGA,A69=,0.0,0.0,,,1.0453964083279033e-13,0.0033942121978019,0.5054428044341671,0.0183606042254647,2.0907928166558065e-13,0.0058519181891395,4.6133826036493256e-05,0.0005251467064196
1OGA,A69G,1.843793103448191,2.220446049250313e-16,0.7644593081891046,3.593682436230444e-06,1.1095402298851904,0.0030885123776342,0.50549075104096,0.0172427834475827,2.16494252873595,0.0021318663208547,0.9699280792718692,0.0007391939511215
1OGA,D612=,0.0,0.0286149188661894,,,2.0907922745547205e-13,0.0007449127240099,0.7707378552197627,0.0012807409968861,1.04539351712211e-13,0.0150051737234695,0.0260396744890866,0.0189886240088799
1OGA,D612A,1.2016091954022672,0.1236562600786213,0.9354141899555168,0.0092117374509829,1.2017241379312351,0.0012902266851058,0.9051585929293244,0.002347120511042,0.7389655172414938,0.0085506735234384,0.0558154321756199,0.0048308638169725
1OGA,D612S,1.3909195402298458,0.0667318349734774,1.1724823653396184,0.0052394963845311,1.135632183908372,0.0008127664151747,1.1386412621467878,0.0021201097937784,0.7911494252874393,0.020315258725504,0.273143653056932,0.0072176908096839
1OGA,D61=,0.0,0.0,,,0.0,0.0,0.6927119898545108,9.240517490917479e-13,0.0,0.0,-0.0060554841399408,0.0006050793010361
1OGA,D61A,-0.1793103448277367,0.0,0.0342479075544392,0.0,0.4202298850575699,0.0007085533336832,1.1353282811489211,0.0045930024908353,0.1736781609194842,0.0588442884573762,-0.0039819763549468,0.0008811343652507
1OGA,D636=,1.0453674962699705e-13,0.0588442884572284,,,-1.0453964083279033e-13,0.0053642583399459,0.5923554461182694,0.0582691544080889,-1.0453964083279033e-13,0.0061748855257206,0.0044834447154484,0.0049113662388162
1OGA,D636A,-1.300114942528596,0.0,-0.4832840017129403,3.603167493704112e-06,0.2919540229885016,0.1571083156818495,0.7138693394290385,0.0041708899407803,-1.0941379310345096,0.001227250373753,-0.3637062125695572,0.005316727886568
1OGA,E154=,1.0453956855264552e-13,0.0009753196980913,,,0.0,0.0009887730191465,0.022858987631297,0.0035126192658371,0.0,0.0162040431171677,-0.3214980007317212,0.0054147668106336
1OGA,E154A,0.9227586206896836,0.0009753196982392,0.0019436175277625,0.0005569333128999,0.9677011494253768,0.0020302898543512,-0.0241768459130688,0.0041957485532386,1.483448275862063,0.0005860941969405,-0.51115438232401,0.001185996284882
1OGA,E58=,0.0,0.0,,,0.0,0.0,0.9568626547698402,0.0,0.0,0.0,-0.0034672632310325,0.0006050792959356
1OGA,E58A,0.9000000000002008,0.0,0.0376800515901965,0.0,0.8910344827585629,1.1102230246251563e-16,1.070849653247128,0.000226904108685,0.960689655172434,0.0,-0.0093312322456015,0.0006050793000751
1OGA,E63=,0.0,0.0,,,-1.0453964083279033e-13,0.0016255328303493,0.7642275462561775,0.0145331806561419,0.0,0.0133323424126983,-0.0024693409049459,0.0021493083467165
1OGA,E63A,1.99172413793098,0.0,0.0390551727710332,0.018189745594882,1.401149425287415,0.0019506393963304,0.6656396484889479,0.0251689914908867,1.1537931034482247,0.0011378729811558,-0.0109139325855073,0.0038621157535815
1OGA,H151=,-1.0454600148553557e-13,0.1204519827262578,,,1.0453964083279033e-13,0.0008127664151746,0.019414930248399,0.0008343201123295,0.0,0.0152800086049589,-0.3202377881260109,0.0035728470340688
1OGA,H151A,0.1995402298849387,0.5114108417073443,0.1709524217542706,0.0742971866667535,0.288850574712739,0.0020302898543512,-0.0096166589798809,0.0008514032480212,0.6698850574714182,0.0128848472713452,0.1412478239991946,0.0030560359909807
1OGA,H70=,3.13618922498371e-13,0.0022757459624595,,,,,,,,,,
1OGA,H70A,2.128735632184272,0.0034977296677218,-0.0129993477486127,0.019311905649324,,,,,,,,
1OGA,H74=,0.0,0.4754704368786537,,,,,,,,,,
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1IAR,I11A,2.2173563218391,0.0009887730192071,-0.066073456341969,0.0012358090036336,2.889425287356287,0.0451579339783288,0.3342693888112734,0.0160871827539829,2.772758620689688,0.0003251065660551,-0.0350547851757903,0.0017790488582216
1IAR,I5=,2.6134187406749262e-14,0.0370621485311306,,,0.0,0.0,0.0120931193775985,1.8480233565654712e-13,2.613497345332431e-14,0.0019775460384176,0.0003171945008525,0.001938115899822
1IAR,I5A,1.636666666666723,0.0027634058115422,1.5105300392095462,0.0078663997731465,1.4444827586207163,2.220446049250313e-16,1.648877873014169,1.6632519366328693e-13,1.3124137931034623,0.0011378729812297,1.851580098472024,0.0043209561861205
1IAR,I5R,1.3267816091954163,0.0334871599239795,1.441256992208853,0.0057308571047932,1.8575862068965847,0.0009753196982022,0.959564358119362,0.0310647451585045,2.580114942528775,0.0012902266850919,2.652372594514747,0.0102639033216552
1IAR,K12=,2.613491020819758e-14,0.0014629795472848,,,0.0,0.1379299808388783,-0.8893099911578267,0.2731820574465551,0.0,0.0186554238267709,-0.1955784297024626,0.0387604236790807
1IAR,K12E,0.825862068965511,0.0,0.5300855306922884,0.0,1.1481609195402598,0.0009753196981652,0.0306139700494205,0.0525419033770635,0.4760919540229946,0.0009050583763383,-0.1673350525556057,0.0009334807628229
1IAR,K12S,1.348275862068994,0.0,0.6266088055776473,8.611747790298865e-12,1.20712643678163,0.0056520877485707,-0.4121860191037939,0.0212377632371565,1.0186206896551817,0.0004300755616879,0.4449512333368126,0.0038361350841015
1IAR,K77=,0.0,0.0559742971798175,,,2.613482889303464e-14,0.0025391634522307,-1.0492962601689744,0.0020063646356353,2.6135343889066576e-14,0.0182059676995287,0.0399767470826609,0.011013810048636
1IAR,K77A,0.4701149425287523,0.0078228503573412,0.0208321268285638,0.0117759148805197,-0.0762068965516731,0.0030885123775973,-0.7738158897826587,0.0040722066490778,0.3460919540229847,0.1605273546040111,0.1938617341497827,0.0102634636211163
1IAR,K77E,0.0014942528735801,0.0497484755590807,-0.0071512663902174,0.0021781917019404,0.1436781609195925,0.079699362441816,-0.5365219183366746,0.4413346896724457,0.3573563218390717,0.0217378172586083,-0.0058887826130244,0.0064086772492522
1IAR,K84=,-2.613491020819758e-14,0.0017880861133399,,,-5.2254497025690703e-14,1.4387591081108164,-0.6107745808900741,0.7885678702162019,-7.840476676466516e-14,0.0010659331603991,0.0372293161406863,0.0015345198916377
1IAR,K84A,1.1640229885057156,0.002113192679395,-0.0169018120434351,0.0003161806179201,0.9936781609194858,1.4268927462269358,0.2101728327151924,1.0039770945596864,1.0844827586206311,0.022340877565823,0.0725075231179519,0.0025600347702962
1IAR,K84D,2.0811494252873035,0.0076538261216634,-0.1068399675759583,0.0044508185283135,3.079655172413729,1.4669621094714267,0.5667880588724064,0.8699898247392942,1.9131034482757583,0.0235702260395485,0.1405930452020406,0.0025209754783276
1IAR,N15=,-2.613491020819758e-14,0.0008127664151746,,,0.0,0.0016255328303124,-1.0196701866671358,0.000692035354688,-5.226980234635895e-14,0.000325106566055,0.0040140637324891,0.0018419624329695
1IAR,N15A,0.0401149425287279,0.0020302898543512,-0.0474315557881322,0.0010093813871991,0.5145977011493833,0.0570902311318286,-1.0352797770876438,0.0046357869605165,0.4417241379309646,0.000325106566055,0.0069958334435127,0.0003967881339095
1IAR,N15D,-0.8405747126436638,0.1053345274043633,-0.0478491655507366,0.0028060677762017,0.0077011494252881,8.673617379884035e-19,-1.0057351045603178,1.8474756079797025e-13,0.1016091954021959,0.0001625532830275,0.0089755711020063,0.0018349221854519
1IAR,N89=,-2.613491020819758e-14,0.0012272503738043,,,5.226982041639516e-14,0.0035761722266799,-112.8340508975673,0.018086387509953,-2.6134874068125164e-14,0.0010659331604132,0.0282120597008522,0.0015226321604448
1IAR,N89A,0.676781609195367,0.0014171066673453,1.1320272770358732,0.001908518423495,-1.501954022988402,1.477609342755324,-113.38315491855168,0.9792780136920516,0.4999999999999634,0.0004300755616879,0.6303245635790936,0.0059500027385758
1IAR,N89R,2.797701149425252,0.0047642256956316,2.2759743458982222,0.0040133422321326,3.3175862068966104,0.0024598775355251,-110.22616367788709,0.0169373074024452,2.5563218390804345,0.0014898254479108,1.995727229255476,0.0097882145079542
1IAR,Q78=,7.840256222024777e-14,0.0655904007748176,,,-5.2273000742767785e-14,0.2146425468289679,-0.7019954767800863,0.2362157903925055,0.0,0.0,0.0115335672612202,1.734723475976807e-18
1IAR,Q78A,0.5600000000000604,0.0604757201110204,0.0584861953095356,0.0041640051235193,0.6058620689654601,0.0009753196981652,-0.52131774982692,0.0206941509740802,0.3881609195402244,0.0130042626425363,0.6274766792682187,2.096397652813878e-05
1IAR,Q78E,0.3050574712644197,0.0668979341801193,0.0611073291076076,0.0037795935013689,0.2091954022987648,0.0029573977770673,-0.6018980841078972,0.0637584983913198,0.8928735632183681,0.0522747197076919,0.5295095180062863,0.1099951129928112
1IAR,Q8=,-7.840471567008005e-14,0.0,,,0.0,0.0,-0.010363281830487,1.8480233565654712e-13,-2.613491020819758e-14,0.002113192679422,0.0009149857123702,0.0029345064464824
1IAR,Q8A,0.929310344827486,0.0,0.2535942003260845,0.0,1.097931034482748,0.0,0.4159510952185046,1.847998907244445e-13,1.5383908045976769,0.1408524900957616,0.648941089002201,0.2371441347003329
1IAR,Q8R,-0.1568965517241912,0.0,-0.7199661043859615,8.685699145338711e-12,0.3622988505746654,0.1895371280146282,-0.6934365069908947,0.1876773981646935,0.7648275862068962,0.0019974881835771,0.5179288095794242,0.0017483324779763
1IAR,R53=,7.840487518488241e-14,0.0559183293627695,,,-7.841875297269024e-14,0.9407817704137764,0.717034062398063,1.167338762861114,5.226982041639516e-14,0.0021869307575319,-0.3632438758696198,0.0075148951904177
1IAR,R53Q,1.6533333333334397,0.0649198414241795,1.0096487208794505,0.0030388541307175,0.3311494252872877,0.1610905495282225,1.235582339874204,0.2288376138512346,2.9544827586207365,0.7408366007907632,1.3007664748846473,0.8931737056083472
1IAR,R81=,0.0,0.0658340796277086,,,7.840473062459274e-14,0.0038843092525831,1.479938248731773,0.0469805692364622,2.613491020819758e-14,0.0024274381703439,0.0460359545452294,0.0019235027816224
1IAR,R81A,0.8251724137930875,0.0660780595090198,0.9529229215324668,0.0017709615995152,0.7554022988506666,0.004102659378729,2.4120259563705697,0.0659082159164118,0.8929885057471271,0.0005860941969508,0.9506831954316676,0.0079096934207025
1IAR,R81E,1.5916091954022704,0.9317602251590764,1.53381787980813,0.2766139941018096,-0.6101149425286564,1.4947635466889049,1.8489839338959928,0.932262863983214,0.968620689655188,0.015524476814573,1.1098797985809843,0.0035943044591204
1IAR,R85=,2.6134548807473425e-14,0.0064777024384465,,,-2.6135054768487247e-14,0.0046633247758722,2.357202848512373,0.0303381645058352,2.6134187406749262e-14,0.0139331966001937,0.0420542945155715,0.0018741055064301
1IAR,R85A,2.631264367816124,0.0448920844573948,2.64202536169091,0.0603044337052228,1.3563218390804546,0.0007449127239735,3.5451810265969823,0.0402207053359022,2.0268965517241657,0.0163517614663178,2.217248346445213,0.0077227486947103
1IAR,R85E,3.848390804597727,0.0066646846042771,4.177843631950494,0.0039855408929189,1.3911494252873116,1.4454237927151306,4.138678577748563,0.9908695710638514,3.4186206896552203,0.1234408910653015,3.57450433983386,0.2837183418526677
1IAR,R88=,-2.620126338115369e-14,2.8389678743557045,,,5.2254497025690703e-14,1.304389441071216,0.4144164843989461,1.1718674876218085,5.226982041639516e-14,0.0052748477726548,1.1237433397034682,0.001403352854116
1IAR,R88A,2.689310344827579,2.067005783231818,2.967732030846539,0.4091521093366331,2.0232183908046344,1.0006447518515813,1.7743196864065318,0.777550940738219,1.1793103448276636,0.0039916678975165,1.9830814697997312,0.0039796739447264
1IAR,R88D,5.918275862068943,2.464227173675879,4.6796044932980765,0.5423983102163151,5.391379310344852,1.2502455195529771,-33.01634876201308,53.07069324477296,3.948390804597768,0.0037493118230633,4.225671355638272,0.0058611697300258
1IAR,R88Q,2.2472413793103105,0.0403868857636024,2.3317152594876167,0.2792156459077769,3.448505747126484,0.1309367451583463,3.324940280123554,0.1989810565686119,0.9409195402299284,0.0015506594900267,1.7640782639680233,0.0028825291074529
1IAR,S16=,2.6134765647907922e-14,0.0022347381718482,,,5.2270109536974495e-14,0.0104034101139847,-0.9794839699360764,0.0217090787091882,-5.226953129581583e-14,0.0174886483387316,0.0067060561477303,0.0015246736817444
1IAR,S16A,-0.4489655172413473,0.0,0.0050296969011312,0.0,-0.5483908045976179,0.0,-1.1170658673710996,0.0,-0.326781609195437,0.0169055414352344,0.088081419457425,0.0027703345702941
1IAR,S16D,0.0626436781609801,0.0018746559115212,0.1568748598554615,0.0014858982285312,-0.1701149425286593,0.0,-1.313279245205116,2.2169705516614906e-13,-0.198850574712698,0.0172329481301296,0.2802352605081016,0.0029850282960092
1IAR,T13=,-2.613491020819758e-14,0.0005860941969867,,,-5.22696758561055e-14,0.0022582623797946,1.6071447120664393,0.0496966859541981,-2.6135054768487247e-14,0.0056520877485707,0.0077169522700356,0.0102362328205519
1IAR,T13A,0.8213793103447967,0.0009050583763018,0.3549653779953263,0.0018860815774668,-1.3339080459770918,1.8282367742540573,0.5982792916001248,0.9804035914421012,1.083333333333302,0.0119926431846371,0.4598135671210849,0.0304212032153004
1IAR,T13D,1.5752873563218308,0.0022347381718482,-0.0716882305391402,0.0013956521099333,1.2212643678160398,0.0002815505451408,-0.3035113694224345,0.0575370599318894,1.5983908045976432,0.0030885123775953,0.5528678588479093,0.0069992113330386
1IAR,T6=,-5.226982041639516e-14,0.0004876598491195,,,0.0,0.0022757459624595,0.1011663545506607,0.0311154848952509,-2.6134901173179483e-14,0.0001625532830275,-0.0016367979665589,0.0026093026223954
1IAR,T6A,1.280459770114902,0.0028758611501653,0.0815108026393778,0.0036215481382564,1.1279310344827442,0.0089758266691117,0.1971067167253216,0.0309515875388907,1.513678160919473,0.0004876598490826,0.4691188993229195,0.0015181833775588
1IAR,T6D,2.982413793103383,0.1187472593922031,1.169482112364028,0.1315525040320979,3.674367816091965,0.1499919405946849,1.6419812585779736,0.2683319915617344,4.208620689655095,0.2690256834169462,1.6228677969684997,0.3901873983940571
1IAR,W91=,2.6134901173179483e-14,0.0001625532830275,,,2.613491020819758e-14,0.0017880861133399,1.1013969584095629,0.01382179574376,2.6134765647907922e-14,0.0026160475119061,1.6719291500296365,0.0046022796185613
1IAR,W91A,2.98022988505751,0.0005860941969507,2.046030870682752,0.0012760277835457,0.5483908045977486,0.0013305559658426,1.499399157330363,0.0212760142560427,-0.1199999999999588,0.000325106566092,1.9277471152153,0.001045509993275
1IAR,W91D,4.698850574712683,0.1706025165554082,1.950429851447176,0.1390150384493434,2.797126436781613,0.0,1.3626045257062505,2.216971663624709e-13,1.676436781609226,0.0005631010903136,1.9974946068487305,0.0027460119850461
1KTZ,D176=,0.0,0.0,,,0.0,0.0,-0.0033094666019318,0.0,0.0,0.0,0.0307583736998273,0.0
1KTZ,D176A,0.8003448275862161,0.0,0.024600615213252,3.469446951953614e-18,1.2655172413793354,0.0,-0.1270827233571285,0.0,1.3348275862069292,0.0,-0.1363112027896195,0.0
1KTZ,D90=,-3.9202437592441207e-14,0.0083947400627644,,,0.0,0.0,-0.0007031126969634,0.0,0.0,0.0,-0.0108833441752842,1.8110566744852144e-12
1KTZ,D90A,1.920804597701112,0.0140840952379294,1.3459823550135492,0.0028523342844224,2.42758620689654,0.0,1.3651466544917543,0.0,1.2864367816091962,0.0055268116230474,0.7609713428160471,0.0018945572849875
1KTZ,D90N,0.3973563218390405,0.006014471472167,0.6831512300947971,0.0005211094421377,0.7286206896551919,0.0,0.3484279352375293,0.0,-0.0979310344827166,0.0,0.2056550838541045,0.0
1KTZ,E113=,0.0,0.0,,,0.0,0.0,0.0058318475424616,8.673617379884035e-19,0.0,0.0,-0.0037027806052751,0.0
1KTZ,E113A,0.4906896551724144,0.0,-0.0076501710760833,0.0,0.6089655172414057,0.0,0.3259777247561832,0.0,0.6951724137931298,0.0,0.4838543836828633,0.0
1KTZ,E133=,-2.613491020819758e-14,0.0030367459341789,,,2.613489213816137e-14,0.000325106566055,0.0012909202300683,0.0004232152298976,0.0,0.0042263853587901,-0.0062021449571409,0.0022109497072259
1KTZ,E133A,2.325977011494239,0.4973408746196531,0.8323241720047436,0.5758566218789185,1.0655172413793603,0.0216415751537597,0.7007244757297203,0.0007012356424454,1.9131034482758629,0.0031013189800749,0.2676187598596395,0.0005974481307935
1KTZ,E177=,0.0,0.0,,,0.0,0.0011378729812297,0.0029120235333083,0.0028892835774849,0.0,0.0,0.2868103822474323,1.7740998058680713e-12
1KTZ,E177A,2.1866666666666803,0.0021318663208011,1.3173590614194408,0.0039709489661006,1.5952873563218544,0.0,0.7082371234168384,1.1102230246251563e-16,1.8506896551724008,0.0,1.3417953259897395,0.0
1KTZ,E177Q,0.5644827586206964,0.0029259590945697,0.4503371366097483,0.0003306812308783,0.3820689655172232,0.0026008525284777,0.1022902348514545,0.0044373261610833,0.7925287356321818,0.0037387255097444,0.9160879071343736,0.0003353313570516
1KTZ,F168=,-5.2273000742767785e-14,0.1358163565472606,,,7.840473062459274e-14,0.0004876598490826,-0.0016147592826582,0.0002612711216628,-2.6134765647907922e-14,0.005067909812631,-0.0009542191542775,0.0014743767706373
1KTZ,F168A,4.032298850574662,0.002715175128972,0.0833498182924191,0.0006152373493342,3.7613793103448727,0.0053716420439305,-0.002720097141541,0.0019022631056221,4.189999999999998,0.2960143487218645,-0.004488513815021,0.0036953492473364
1KTZ,F88=,2.8912057932946783e-19,0.0064960327130821,,,0.0,0.0,0.0260279562007389,0.0,0.0,0.0,0.0199514539325452,0.0
1KTZ,F88A,2.280804597701132,0.0826584642984318,1.844602512493992,0.0764155293947931,2.184942528735634,0.0003251065660551,1.0488288701370443,0.0002764822116001,1.9248275862068551,0.0,1.2379316410287458,0.0
1KTZ,H137=,2.6134765647907922e-14,0.0063395780382221,,,0.0,0.0006502131321471,-0.002240452792711,0.0019486217274267,2.6135343889066576e-14,0.00788509098214,0.0196504730084943,0.0003850091392904
1KTZ,H137A,1.9362068965517405,0.0404845796453534,0.014106525403472,0.0003612939086042,2.1578160919539866,0.0008127664151378,0.0015609082021685,0.0002447123966723,1.773563218390786,0.0004876598491196,0.0190226106358478,0.0006059008255707
1KTZ,I108=,2.8912057932946783e-19,0.0055196354958805,,,0.0,0.0,-0.0148067329565366,1.734723475976807e-18,0.0,0.0,-7.074318887134723e-05,0.0
1KTZ,I108A,3.3309195402298903,4.440892098500626e-16,1.5078306289999075,0.0,3.089310344827529,4.440892098500626e-16,1.660428743550632,0.0,2.918275862068954,4.440892098500626e-16,1.0377297922955144,0.0
1KTZ,I111=,0.0,0.0,,,-2.6134765647907922e-14,0.0027151751289784,-0.0084665387827494,0.0025038191033511,0.0,0.0,0.0185007816427404,0.0
1KTZ,I111A,2.373448275862043,0.0,1.417532088512887,0.0,2.912758620689617,0.0,1.5531687102529288,0.0,2.183103448275829,0.0,1.4443055659069814,1.7926269026064809e-12
1KTZ,I183=,0.0,0.206523994070498,,,0.0,0.0011378729812218,-0.0006014873652386,0.0006475120002313,0.0,0.0017880861133769,1.2482449677207492e-06,4.7739841965474566e-05
1KTZ,I183A,2.8218390804597653,0.2536663122398787,0.0548450929293188,0.0552495955552487,2.667356321839069,0.0022757459624595,-0.0013976139464323,0.0003178010515319,1.89689655172413,0.0009050583763383,-1.78720297534365e-05,4.922355267754369e-05
1KTZ,L85=,-3.920235783504001e-14,0.0,,,0.0,0.0,-0.0053199223501796,0.0,0.0,0.0,0.0012636048447332,0.0
1KTZ,L85A,2.5899999999999888,0.0,1.257697931574622,0.0,2.39896551724139,0.001462979547285,0.9494012642214288,0.001051272792462,2.5265517241379305,0.0,1.5222737958348609,0.0
1KTZ,M170=,2.6136500371383893e-14,0.2386054077891726,,,2.6134765647907922e-14,0.0104755470253572,0.0018574127640367,0.0019096816822115,1.1564823173178713e-18,0.0254441326098093,-0.0535808910244825,0.0027668343880332
1KTZ,M170A,2.4078160919540603,0.0721914118656208,0.0732320442329438,0.0177176255134042,1.9895402298851064,0.0004876598490826,-0.0029856111364253,9.93804206905044e-05,1.1679310344827916,0.0160927750200967,-0.0010585934414743,0.0018079846601487
1KTZ,N105=,3.920235783504001e-14,0.0,,,0.0,0.0,0.0021946149081486,0.0,0.0,0.0,-0.0034296001179992,4.336808689942021e-19
1KTZ,N105A,1.6303448275862686,0.0,0.0954702583294812,0.0,1.578275862068965,0.0,0.0019023810297124,0.0,1.638965517241355,2.220446049250313e-16,-0.0031757359113794,1.7925764000314185e-12
1KTZ,R13=,-1.306745510409879e-14,0.0008446516354385,,,-2.613491020819758e-14,0.0020753413891229,-0.3631718601661629,0.004462143677904,2.613491020819758e-14,0.0014629795472848,-0.0691301624191635,0.001525093185488
1KTZ,R13A,1.5417241379310358,0.0,1.241889635168718,6.555131098103217e-06,1.6906896551723944,0.0006502131321101,0.7114346190933797,0.0007883213102691,1.777126436781663,0.013491922491582,1.243057285843806,0.0007032571640182
1KTZ,R13K,1.122298850574701,0.00181011675264,1.0423295134811092,0.0023992215443013,0.9825287356321842,0.0037387255097075,0.5012762900286487,0.0017768686522086,1.330459770114974,0.0013004262642573,1.28052585194518,0.0015433697318257
1KTZ,R64=,3.9202437592441207e-14,0.0032510656606248,,,0.0,0.0,-0.0008069011853265,0.0,0.0,0.0,0.0104396630902572,1.829536335621049e-12
1KTZ,R64A,0.9767816091954468,0.0048765984909373,0.9795174970471684,0.0039921566054103,2.215632183908028,0.0013004262642203,1.688458924546655,0.0008114127055237,1.6724137931034957,0.0,1.245738534265396,1.8481035026298388e-12
1KTZ,R64K,0.302988505747188,0.2418792851506993,0.8991737094580046,0.373310679061675,0.8812643678160823,0.0011378729812297,1.0666910384619033,0.003688749655072,0.4896551724138182,0.0,0.8263615548473573,0.0
1KTZ,S107=,3.920235783504001e-14,0.0,,,0.0,0.0,-0.0146404222077135,1.734723475976807e-18,0.0,0.0,-0.0017762167293108,0.0
1KTZ,S107A,0.6001149425287622,0.0065021313212496,-0.1104352680519288,0.0535704235909636,0.6051724137930627,0.0,-0.189056385091621,2.775557561562892e-17,0.7144827586207297,1.1102230246251563e-16,-0.2005496404615706,1.82953715340084e-12
1KTZ,S110=,0.0,0.0,,,2.8912057932946783e-19,0.0035278182191121,-0.0076977000329516,0.0037743150187719,0.0,0.0,0.0166405116154801,0.0
1KTZ,S110A,-0.5689655172413585,0.252120141981675,-0.204577445098802,0.2548285893016528,-0.6705747126437113,0.0011378729812297,-0.3291050746910012,0.0018524289181237,-0.6440229885057808,0.0016255328303123,-0.2461435127650307,0.0033668160759935
1KTZ,S110L,9.02689655172415,0.001462979547285,7.493111346821927,0.0009689627516301,7.016436781609183,0.0003251065660551,5.840571704440516,0.0068201491972564,9.308620689655134,0.0,8.354612672781803,0.0
1KTZ,T109=,-3.920235783504001e-14,0.0,,,5.226982041639516e-14,0.0009753196982022,-0.0193712780182637,0.0029770996637784,-2.613491020819758e-14,0.0004300755617159,-0.0899243409618071,0.0024019417229573
1KTZ,T109A,1.8311494252873348,0.0937932443091118,0.090085988539843,0.1572794640962063,1.3441379310345305,0.0,-0.2582121831430241,0.0,1.3063218390804086,0.0,-0.0875230944414256,0.0
1KTZ,V120=,0.0,0.0018746559115332,,,2.613489213816137e-14,0.000325106566055,7.258446388753316e-05,0.0009180379077512,7.228014483236696e-20,0.0023612228257482,-1.4384610685529075e-05,0.0001485932771793
1KTZ,V120A,2.637701149425298,0.109484553640209,0.0935458444813509,0.000121882318008,2.306321839080466,0.0036601570869047,0.0080967969269368,0.0021962628681661,2.6793103448275537,0.0003251065660551,-0.0560767426173467,0.0025572662185446
1KTZ,V135=,-3.920214847186188e-14,0.0078245390460333,,,0.0,0.0,0.0026778164977588,0.0,2.613491020819758e-14,0.0009753196982022,0.0128383813959338,0.0009853799220028
1KTZ,V135A,0.6544827586206459,0.0001625532830275,0.1072480023803522,0.0015828292949938,1.0444827586206884,0.0,0.1188351934276538,0.0,0.9931034482758996,0.0097531969818744,0.0257643444407985,0.0036952014928195
1KTZ,V62=,0.0,0.0,,,-2.613491020819758e-14,0.0007085533336875,-0.005298887866677,0.0007156707815619,0.0,0.0,0.0027030312401558,0.0
1KTZ,V62I,-0.1558620689655166,0.0,-0.0622959839449777,0.0,-0.1525287356322098,0.0011378729812297,0.0238136203386696,0.0016991569192127,0.1403448275862334,0.003901278792735,-0.0473849774411242,0.0409875273666544
1KNE,A3=,-1.3067382823953958e-14,0.0021131926794043,,,0.0,0.0,0.0086670726369577,0.0,1.3067446069080687e-14,0.0001625532830275,0.0173842038485279,4.122775842450029e-05
1KNE,A3F,-0.4274712643678284,0.001065933160404,-0.8029455164426113,0.0014160941123025,-0.8158620689655122,1.1102230246251563e-16,-1.0917750608494174,0.0,0.3280459770115056,0.1123839369890982,-0.2846419365707057,0.0036457628511879
1KNE,A3K,-0.0645977011494397,0.0011262021805873,-0.0092133531348643,0.000910794091767,0.1593103448275824,0.0,0.0949979150815567,1.3877787807814457e-17,0.5190804597701303,0.0003251065660643,0.391857945340629,0.0019588717307326
1KNE,A3L,-0.3067816091954134,0.0016255328303124,-0.1828767022002094,0.0019712267546249,-0.0094252873563145,0.0001625532830275,-0.0200802644716749,0.0016383549536267,-0.0780459770114781,0.0,-0.2007300149344915,0.0001003432754708
1KNE,A3T,0.2001149425287209,0.000325106566055,0.0317588958778999,0.003633113488195,-0.0168965517241304,0.0,-0.0121489952589066,0.0,0.2837931034482817,0.1125682365244461,0.1158124003560991,7.377145507147175e-05
1KNE,D40=,6.531812128211338e-15,0.0495787513245751,,,6.5337275520493946e-15,0.0003251065660643,0.0972914788182532,0.004270776421586,1.306745510409879e-14,0.0003251065660643,0.0156505068125187,2.6844057255274448e-05
1KNE,D40F,-0.3750574712643586,0.0003251065660643,-0.8912955414439206,0.0004070032464878,-1.3294252873563124,0.0,-0.8962414812518303,0.0,-1.4448275862068762,0.0014171066673485,-1.0638565052724271,0.0020303265113771
1KNE,D40I,1.2677011494252934,0.0738013387462588,0.0594932787645243,0.1223655418663105,-0.145517241379306,0.001300426264248,-0.3678942765042812,0.0034010979157726,0.7545977011494447,0.0568139421183311,-0.01458950292378,0.2234190541518511
1KNE,D40K,0.7185057471264341,0.0,0.0835225610348128,0.0,-0.3308045977011347,0.0,0.0551929720051537,0.0028016021189478,-0.6695402298850365,1.1102230246251563e-16,0.199225789006883,2.775557561562892e-17
1KNE,D40T,0.5090804597701251,0.0837532819304008,0.1256838875041462,0.0723922843387784,-0.2535632183907935,0.0,0.1224517142866908,0.0,0.38425287356324,0.2228605510360422,0.7403155822302697,0.3084865390493876
1KNE,K24=,-1.3067382823953958e-14,0.0025024759835795,,,0.0,0.0,-0.0009221694054907,0.0,0.0,0.0009753196981929,0.0021861813530448,0.0007036230858379
1KNE,K24A,0.102298850574698,0.0900760824023398,-0.0713664041630759,0.0017212930384088,0.118275862068952,0.0,-0.0381353727389186,0.0,0.1841379310344799,0.0,-0.0347363039238232,0.0
1KNE,T54=,-9.251858538542969e-18,0.1888174462516245,,,0.0,0.0,0.0011700722024086,0.0,-1.1564823173178713e-18,0.0297485831688687,-0.0328109633543252,0.043665113273663
1KNE,T54F,-0.8481609195402321,0.0034252102128235,-1.4460233059924092,0.0014351706128562,0.7600000000000028,1.1102230246251563e-16,0.3164750395934209,0.0,-0.115977011494261,0.0054908372011481,-0.7127060140728364,0.0026065072144275
1KNE,T54I,0.1714942528735588,0.0048028925093667,-0.2326602115925651,0.0040635200847478,0.7959770114942607,0.089566858950294,0.2141853068101534,0.0774676083792185,0.8620689655172349,0.1153202987509268,0.2931411102492842,0.0046692707066527
1KNE,T54K,0.2209195402298814,0.0075355325991189,-0.2323268687372391,0.0086591052171861,1.0741379310344858,0.0014629795472757,0.3811898222694422,0.0016382287097498,1.0413793103448217,0.0014898254479169,0.4000109113585221,0.0033728136250862
1KNE,T54L,0.3559770114942506,0.0519588544188324,0.0980924227300369,0.0904880818114406,1.3090804597701229,0.1149251711032011,0.3443736858155941,0.0818856027221065,0.3020689655172398,0.0011262021805873,-0.3969235558294103,0.0023396156987319
1AO7,A149=,0.0,0.0005631010902816,,,0.0,0.1436971021997513,0.1210756769688518,0.1001470122666583,3.136187779380813e-13,0.0020367867984402,-0.0043780311931897,0.0050361977212601
1AO7,A149G,0.7821839080460106,0.0011378729811981,-0.0533900702566302,0.0022447624550539,1.0073563218390946,0.1469481678603022,0.0227960122214656,0.0697579746001781,0.7905747126439575,0.001489825447923,0.0134455031615937,0.0016714340098246
1AO7,A150=,1.568091721286062e-13,0.0034136189436893,,,-2.0907928166558065e-13,0.0203425545842892,0.1074704232449994,0.1079124485771862,0.0,0.0,-0.0046367692084459,9.14198999279022e-06
1AO7,A150G,1.3160919540231768,0.0017880861133399,0.1686326449580728,0.0222601478451532,1.0743678160917165,0.0235601343650192,0.2620942825871847,0.068831766986653,1.3365517241376876,0.0,0.3043419265648627,1.0132794184921442e-05
1AO7,A150P,7.297241379310487,0.2027306650522187,0.8217404143342405,0.1175634626360086,5.647701149424999,0.0034136189436155,1.0469573642296968,0.0077284302812094,10.3406896551722,0.0,-1.2742848151360338,3.99551368567157
1AO7,A158=,5.226982041639516e-14,0.0026611119316852,,,1.0454600148553557e-13,0.2644897769653415,0.2809882798253799,0.3732029490821125,2.0907812518326333e-13,0.0995224427312811,0.0250076440557029,0.0338683858891634
1AO7,A158G,1.389885057471276,0.0051094507519356,0.7444660209497064,0.0944465964828611,1.394597701149717,0.0121458960282782,0.911918573290353,0.033877488128684,1.4752873563220523,0.0099516601479494,0.7644116487159178,0.0042283976491325
1AO7,A548=,2.312964634635743e-18,0.0874541194851515,,,0.0,0.0460421951724667,-0.034041716766474,0.1362346203184836,1.0453964083279033e-13,0.0174795805978284,0.0056094328783206,0.0001902109597898
1AO7,A548P,-0.7670114942528476,0.0007449127239615,-0.4462735891964822,0.00160467576016,-0.639310344827679,0.000325106566129,0.0374887842433796,0.0518759158448234,-1.1040229885055926,0.0060144714722039,-0.0063670063152141,0.0011380900471477
1AO7,A594=,5.2269603575960666e-14,0.0036925007825578,,,-1.0453906259163166e-13,0.0342131220387879,0.1698696972046794,0.0576026015540632,1.0453964083279033e-13,0.0034136189435731,0.0168004583645534,0.001373644863213
1AO7,A594K,0.3894252873563649,0.0048955263078804,-0.6637076173547553,0.023082079522528,-0.3519540229885986,0.0190548228266247,-0.057054440922786,0.0451474387385169,0.979885057471327,0.0051326697843249,-0.0976785600865152,0.0036994861614792
1AO7,A594M,-0.0325287356321203,0.1391419072010222,-0.7344696679443253,0.2424554027113373,-0.9036781609195496,0.1042369679536911,-0.0629484741643184,0.1376204546625834,0.3981609195402232,0.0052093191693905,-0.5017745044478524,0.0029749719782172
1AO7,A69=,5.226978427632276e-14,0.0015676070916049,,,1.0453674962699705e-13,0.0946767870971738,-0.5341795796414448,0.3697518178466939,0.0,0.0,0.0163295249913271,9.062022089306749e-06
1AO7,A69G,2.32885057471264,0.0044724313697198,1.1221354715719607,0.0198427810122455,1.895862068965586,0.0501610565018044,0.8217812457548369,0.0643683446829261,2.1686206896550897,0.0,1.2283305702115694,9.058729884212055e-06
1AO7,D409=,1.5681900222830336e-13,0.3434977037475769,,,0.0,0.0,0.0141280524118475,0.0013601724803785,0.0,0.0,-0.0221973193719736,9.067449936619454e-06
1AO7,D409A,2.341494252873783,0.3130776231185202,-0.2275868846661184,0.2849188137282393,1.892528735632305,0.3026742130044617,0.5484668224516487,0.3448377594986246,2.193103448275749,0.0,0.0323194237966811,9.067449419173397e-06
1AO7,D409M,0.4256321839081998,0.3343038981434814,-1.8094460567821984,0.0630981588164034,-0.4217241379310194,0.0,0.096894364135279,0.0517997142938246,0.3555172413792928,0.0,-0.0022047447327032,9.067449862698567e-06
1AO7,D409P,3.953678160919742,0.3537250201494872,-0.4139193890245976,0.1337689728921471,3.310804597701264,0.0026008525284407,0.0765425247510424,0.0549264060388362,3.0589655172414125,4.440892098500626e-16,-0.0039546880117117,1.3305719919639797e-12
1AO7,D409V,0.7404597701151525,0.318220752130969,-1.0457761989305936,0.0562062263711791,0.4585057471265973,0.0008127664151746,0.0233462991294716,0.0511995771980713,0.4513793103448953,0.0,-0.1509545272923181,9.067448753895935e-06
1AO7,D409W,-0.2948275862066937,0.2921480484790794,-3.513106844223424,0.543113256425205,0.1159770114942545,0.3020272806661445,-2.1880320120391485,0.2873578507438407,-0.4248275862068865,5.551115123125783e-17,-2.849861448515592,9.06745001066975e-06
1AO7,D476=,-5.226982041639516e-14,0.0037245636197833,,,1.4456028966473392e-19,0.0091767051293161,-0.0793265539124703,0.0147032230511789,1.0453992995336965e-13,0.0079451814522883,0.0123230254420137,0.0012012606839534
1AO7,D476A,0.5803448275861521,0.1014055013474776,-0.4074976697645081,0.1821326567793205,1.078160919540347,0.0,0.8177672009028827,7.048980933901349e-07,2.238160919540306,0.0060800143242893,0.498235089434243,0.0017279846062608
1AO7,D476N,0.5872413793102838,0.104865389432887,-0.2138036843416557,0.1984144632628505,0.9602298850573976,0.0,0.7323729971188385,0.0538376163846476,1.4703448275863542,0.0062281458317704,0.6456569891008842,0.0010222895240752
1AO7,D61=,0.0,0.0,,,-1.0452749776845849e-13,0.1776707383532846,0.0366493379217262,0.0514852739573095,0.0,0.0,-0.0168598181235942,9.0674488278079e-06
1AO7,D61A,0.2789655172412902,0.0,-2.0078887995787125,3.11558764706281,0.1601149425287389,0.0,0.1835515422068976,0.0911285749947644,0.2555172413793053,0.0,0.3429190540359793,2.0697743844042884e-12
1AO7,E154=,0.0,0.002113192679395,,,2.0907929973561692e-13,0.0097165536577166,0.089561407480269,0.0932591866018178,2.09079137105291e-13,0.0031013189800419,-0.0098268330083524,0.0022310372375815
1AO7,E154A,0.915287356321809,0.0006502131321101,-0.0189874294200904,0.1013295731942104,1.511954022988662,0.1593032125918384,1.2751871831181851,0.0784896898238792,1.4355172413795756,0.0026008525284407,0.7219695855348681,0.0032706637648899
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1AO7,R590=,1.0454600148553557e-13,0.7637870233189316,,,9.251858538542969e-18,0.2302825873192814,0.037722121064428,0.0912069050730838,1.0453920715192133e-13,0.0073796326066107,-0.0001959132340294,0.0026267625864282
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1AO7,R65=,4.625929269271485e-18,0.1159008327783248,,,3.1360099702245253e-13,0.5405548545701289,0.2040398869392175,0.4718289049317397,2.0907928166558065e-13,0.0045077405864914,0.2913859320148637,0.0029287907654478
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1AO7,R75=,-5.2273000742767785e-14,0.1123243185746587,,,-4.625929269271485e-18,0.0926769000072558,-0.5110769951681045,0.3828020971905319,2.0907928166558065e-13,0.0191812873977679,0.0025787784836901,0.0013385461550518
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1AO7,S412=,-5.229150445984487e-14,0.3371386832486364,,,1.0454600148553557e-13,0.3014230133930823,0.1507577474330901,0.3423190076732357,-3.13618922498371e-13,0.0036311652871753,-0.0106717969972134,0.0008538659472849
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1AO7,S414=,9.251858538542969e-18,0.2639070947958221,,,-2.0907812518326333e-13,0.0220695641682143,0.1727705165428139,0.0771791536453239,0.0,0.093453153369714,0.0466747603924635,0.0777639743134135
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1AO7,S477N,0.4186206896551001,0.1199646532695718,0.2227909547954023,0.2778434537600035,0.2987356321839264,0.1113689306337557,0.2498324344975932,0.0794610182452709,0.3637931034481672,0.0208068202279694,0.242777896936755,0.0052508699612099
1AO7,S477T,-0.2827586206897639,0.0008446516354224,-0.0931008301310204,0.0757974709560956,0.4374712643678729,0.0208372766779612,-0.804655265809084,0.0537416457024582,-0.0180459770115118,0.0959093298423651,-0.0758235981241853,0.0146906193274304
1AO7,S477Y,6.944022988505644,0.158724187457298,5.227791501007002,0.0918722071215569,4.152988505747267,0.0597208019384349,3.2412659404319086,0.0909427898854126,2.2411494252874142,0.0004876598490456,0.4810846459779362,0.0129289922415602
1AO7,T163=,-5.2273000742767785e-14,0.1657102163694975,,,-7.228014483236696e-20,0.0080934559734335,0.6890489634105998,0.0843762094298116,-2.090794262258703e-13,0.006014471472178,0.0012887067523165,0.0026240784799118
1AO7,T163A,0.1148275862068731,0.0021131926794689,-0.4152775465546705,0.008150711512642,-0.1906896551722691,0.0035761722266799,0.0420741098975051,0.0317520610089372,0.7574712643674147,0.0037387255097444,0.3813668936527392,0.0007004626102773
1AO7,T474=,-1.0454600148553557e-13,0.19189943473236,,,2.090734992539941e-13,0.2957114979142886,0.3410966892706397,0.3161911946022406,-1.0453964083279033e-13,0.0091276237683609,-0.0113744543288138,0.0079779997919467
1AO7,T474A,-0.2224137931035465,0.1978345580353065,-0.3342472161991292,0.0437426171698543,0.7772413793105213,0.273756379211945,0.5440084705978525,0.3218001734824724,0.9786206896550822,0.0051685809553202,0.1383782880363479,0.0019830017598023
1AO7,T475=,2.8912057932946783e-19,0.0112936518249138,,,-1.0454600148553557e-13,0.2956396470340721,0.5123199347026038,0.3659454266963435,1.0453964083279033e-13,0.0069897911702953,0.0014622488684501,0.0054027635989922
1AO7,T475A,2.035862068965516,0.006136251869,0.2050413448629721,0.0995206791038812,1.882298850574632,0.3050351662280623,0.6425066768406918,0.3149089502229141,1.8088505747127577,0.0052017050570292,-0.209595137900066,0.0026277142516331
1AO7,T64=,-5.2268374813498524e-14,0.0689225920053059,,,0.0,0.0,0.0553558884100322,0.0821760725605772,0.0,0.0,-0.0178971582001144,9.067450675826408e-06
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1AO7,T73=,-4.625929269271485e-18,0.1512794772874982,,,1.045396046927179e-13,0.0006502131321101,-0.2281999870041775,0.0669809238871534,0.0,0.0,0.0080191542230917,9.0796158012833e-06
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1AO7,T80=,1.5680943134016005e-13,0.0,,,-2.0907957078616e-13,0.0101136362792049,0.0259135841703425,0.069849059112176,0.0,0.0,-0.002292759725752,9.064924436763413e-06
1AO7,T80A,0.6555172413795688,0.0,0.0493995646567635,0.0745043110179454,0.6486206896549668,0.0112420609529954,-0.0190046592794307,0.0291752456756865,0.7137931034484891,0.0,-0.0017308281681396,9.07424435544672e-06
1AO7,V152=,1.4456028966473392e-19,0.0028896103655142,,,-4.625929269271485e-18,0.1554011936299693,0.0939210586296934,0.0412063267799553,0.0,0.0,-0.0037954706062762,4.336808689942021e-19
1AO7,V152A,2.264252873563174,0.0101566538088617,0.1204914596595616,0.0258127047667447,2.3373563218391893,0.1570264714083797,0.900160296657106,0.104991463881614,2.56839080459773,0.1030587814419038,0.3514233880684316,0.2322969121567705
1AO7,V381=,-5.2273000742767785e-14,0.0873225887682253,,,0.0,0.0057792207310284,-0.0102703664067549,0.0023371384813002,0.0,0.0,0.0150070943265285,9.341169251136476e-06
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1AO7,V546=,-5.2268374813498524e-14,0.1155911583720094,,,2.0907812518326333e-13,0.0833866654549193,-0.0587704721836458,0.1635013233304591,0.0,0.0024055689122169,0.0113208271711206,0.0031451235275999
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1AO7,V67=,0.0,0.0053642583400199,,,-2.0907928166558065e-13,0.0081714356722636,0.1159060597392872,0.000725808390092,-1.0453906259163166e-13,0.0197674416798199,0.0047985235169003,0.0021557572688339
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1AO7,V76=,5.2263748884229244e-14,0.1021202108076699,,,0.0,0.0044546718103473,-0.1857929287449412,0.0556315074907417,-2.0907928166558065e-13,0.0020302898542092,0.0095062438497828,0.0007235441243115
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1AO7,W167=,1.8503717077085938e-17,0.4440637059891771,,,-1.0453906259163166e-13,0.0201913164210896,0.0099254445003889,0.0010162097885209,0.0,0.002438299245524,-0.0138574091055614,3.5774966913529915e-05
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1AO7,W478=,-5.2273000742767785e-14,0.3957076807887969,,,-3.136148748102604e-13,0.1005352303455825,-0.0420922425521779,0.1406977442324502,0.0,0.0049331640767348,0.0660843200337736,0.0123575872135363
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1AO7,Y159=,1.0453956855264552e-13,0.0009887730192133,,,0.0,0.2860250079839165,0.3932092378639957,0.318277046203973,-1.0453964083279033e-13,0.0017880861134138,-0.009779707771099,0.0032773849125096
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1AO7,Y379=,-5.2268374813498524e-14,0.0705284583908146,,,9.251858538542969e-18,0.282193763434947,0.3459960734473247,0.3471362870026639,1.4456028966473392e-19,0.0054376442171826,0.006465483596724,0.0045033907955681
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1AO7,Y382=,0.0,0.947529110361338,,,3.1361950073952965e-13,0.147685092378161,0.6598004315733776,0.0259197731732976,-3.1362875259806816e-13,0.206942587470997,0.0228671191393653,0.0369453881830758
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1AO7,Y433=,-5.2270109536974495e-14,0.0090110837345067,,,2.0907928166558065e-13,0.0074721484887824,0.0439930944932565,0.0723250536337407,0.0,0.002438299245524,-0.0227730950153,0.0091365002244942
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3SZK,D330=,0.0,0.0,,,0.0,0.0,-0.0140463691386998,0.0016670389720764,-5.226982041639516e-14,0.0007085533336832,-0.2820365697785203,0.0040884068448717
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3SZK,D333A,0.2555172413793576,0.1461451651649896,-0.0014951676771958,0.001610874516132,0.7317241379309806,0.0,-0.0039599689809369,0.0,0.7075862068965458,0.0014448051827841,-0.2877599732939688,0.0002042909696751
3SZK,D402=,0.0,0.0,,,0.0,0.0,-0.1217547169986134,1.3877787807814457e-17,0.0,0.0,0.0069986412875644,0.003500339436877
3SZK,D402A,1.0279310344828352,0.0,0.0542691880002752,0.0021336199120264,1.556896551724094,0.0,0.4814322317433206,5.551115123125783e-17,1.0496551724139047,0.0,0.063132161923367,0.003500339436877
3SZK,D403=,0.0,0.0,,,0.0,0.0,-0.0003480070148432,0.0017191785976303,0.0,0.0,0.0045087750205029,0.0
3SZK,D403A,1.2168965517241368,0.0,0.0056630962533996,0.0,1.5558620689655764,2.220446049250313e-16,0.0062328879958244,0.001396515447696,1.1855172413793456,0.0,-0.0011553715170646,0.0
3SZK,E405=,0.0,0.0,,,5.226982041639516e-14,0.0050391517740387,-0.1278916497580442,0.0038971588007814,0.0,0.0,0.0060101249494113,0.0035003394370248
3SZK,E405A,0.6365517241379323,0.0,-0.0157921914613576,0.0021336199119525,0.5787356321839435,0.0058519181891395,-0.132462162724216,0.0047086160230771,0.6710344827587474,0.0,0.0024600066102323,0.0035003394368031
3SZK,E406=,0.0,0.0,,,-5.226980234635895e-14,0.000325106566055,-0.1339255201579864,0.0026350737560246,0.0,0.0,0.0092643631234395,0.0035003394368031
3SZK,E406A,1.6982758620688714,0.0,0.0076222395889623,0.0021336199119525,1.6580459770113585,0.0,-0.1202568074321444,0.0,1.7213793103448929,0.0,-0.0047698334465794,0.003500339436877
3SZK,F325=,0.0,0.0,,,1.5680931668889588e-13,0.0018462503912837,-0.0466915197006235,0.0082890184828089,-1.5680975036976485e-13,0.0372768385183445,-0.6249345274755828,0.0011715548599459
3SZK,F325A,1.7534482758621337,0.0004876598491195,0.5704575518789746,0.0279307342775842,2.552643678161034,0.0008127664151747,1.3902391266350838,0.0072790552627717,1.4718390804596468,0.0021131926793951,0.1885131205448613,0.0014726140042794
3SZK,F326=,0.0,0.0,,,0.0,0.0039114251786786,-0.0603036885005512,0.0043991268673643,0.0,0.0036601570868948,-0.661509080663689,0.0032809467037942
3SZK,F326A,4.125862068965568,0.0042513200020742,3.3029616808609465,0.0058910279166387,3.920459770115015,0.0076607276795211,3.2118282926470805,0.0051538292602952,3.889425287356292,0.013284691296994,2.5502673418917365,0.0022232969876182
3SZK,G404=,0.0,0.0,,,0.0,0.0,-0.130342755634078,0.0,0.0,0.0,-6.849297435486546e-05,0.0035003394366552
3SZK,G404A,1.386551724137995,0.0,-0.0223037384718224,0.0167869820297497,0.6951724137931298,0.0,-0.3295213120970308,0.0,1.438275862068904,0.0,-0.0193518254332309,0.0035003394367292
3SZK,H324=,-5.2270109536974495e-14,0.0172329481301106,,,-1.0453732786815569e-13,0.0807477604589311,-0.1358755474243533,0.0305039027687027,1.734723475976807e-18,0.0504166809976677,-0.3282995834226166,0.0213445943161526
3SZK,H324A,1.6095402298850754,0.0063395780381852,0.0650150120167507,0.0196684688967619,0.8732183908044647,0.0911242736094638,-0.2164381345135385,0.0044279388476924,1.2520689655172448,0.0561693925602162,-0.351045480601897,0.0016464481880238
3SZK,K338=,0.0,0.0,,,0.0,0.0,-0.0038443192734748,0.0,0.0,0.0,0.0024751137920477,0.0035003394368031
3SZK,K338A,1.1989655172413316,0.0,5.331520665565442e-12,0.0,0.4417241379310169,5.551115123125783e-17,-0.0038443192223549,4.336808689942021e-19,0.5431034482757994,0.0,0.0024751137674287,0.0035003394368031
3SZK,K339=,0.0,0.0,,,0.0,0.0,-0.0025628794931216,0.0018122294805927,0.0,0.0,1.0506231899790724e-11,1.6155871338926322e-27
3SZK,K339A,0.8886206896552502,0.0,-0.007343973999463,0.0167868073414458,0.7582758620689893,0.0,-0.0012814397315332,0.0018122294805188,0.5686206896551336,0.0,3.2929980581433606e-11,0.0
3SZK,N317=,0.0,0.0,,,5.226982041639516e-14,0.0027054258151923,-0.0072551736965234,0.0039274301350884,-1.0453906259163166e-13,0.0572545338713724,0.0210497747259758,0.0152756072816207
3SZK,N317A,0.9952873563218512,0.0016497356430327,-0.0077470473004346,0.0188514387501785,1.0345977011494487,0.0025339549063315,-0.0052401866306072,0.0011086216609003,1.032413793103288,0.0551055629476318,0.0309678764390276,0.0015515368537234
3SZK,N348=,1.045396046927179e-13,0.0006502131321101,,,5.226982041639516e-14,0.0016255328302754,-0.0079860588051104,0.0023185497359282,0.0,0.0,-0.3242074978851602,0.0046209617928279
3SZK,N348A,1.0173563218392505,0.0002815505451407,1.6053282956699642,0.008670267601718,0.5358620689655473,0.0027345694835039,0.0887050024480283,0.0012475725702379,0.7972413793104666,0.0,0.3706217315064496,0.0049321448964516
3SZK,Q321=,-5.227068777813315e-14,0.0956651965565642,,,0.0,0.0016971060988408,-0.0099284053716808,0.0038485096007496,1.5680975036976485e-13,0.0170820221744788,-0.1015639063565498,0.0230209915295228
3SZK,Q321A,1.239655172413724,0.009795099899014,0.1518103834849108,0.0126837958994508,1.0290804597700598,0.0883020495160913,0.0500749608821955,0.0062418924959097,-0.251839080459643,0.0869012648481414,-0.0477979948357841,0.0058816385246141
3SZK,S351=,-5.226978427632276e-14,0.0006502131321101,,,0.0,0.0,-0.0102879718799848,0.0019758003357823,0.0,0.0,0.0028856942042003,0.003500339436877
3SZK,S351A,0.075287356321862,0.0004876598491195,-0.2269333729825235,0.000524579523218,0.3658620689655687,0.0336485295874782,-0.163351323815617,0.0022634672430267,0.2720689655173154,0.0,-0.1467462980516412,0.0
3SZK,T320=,0.0,0.0,,,0.0,0.0,-0.0003846925026915,0.0017408230875583,5.226982041639516e-14,0.0018318824656275,-0.0740956127136651,0.0021040781610003
3SZK,T320A,1.5296551724138443,2.220446049250313e-16,0.0970851732750063,1.3877787807814457e-17,1.3675862068966722,0.0,0.0934435519693893,0.0019556202638758,1.3839080459770077,2.220446049250313e-16,-0.0559039566286597,0.0
3SZK,T352=,0.0,0.0,,,5.227068777813315e-14,0.0342987427196623,-0.111370697841371,0.0037618477750303,0.0,0.0,0.0058763833371342,0.0035003380113907
3SZK,T352A,1.6668965517240804,0.0009753196981652,1.2438158294492696,0.0018609062212824,0.5112643678161288,0.0295846975117526,-0.1669092644757236,0.0068161854664802,1.427931034482785,0.0,1.346679291728394,0.0
3SZK,V309=,0.0,0.0,,,-1.807003620809174e-20,0.0009050583762885,-0.0027029551862226,0.0017663248524995,0.0,0.0,-0.2970788883992319,0.0
3SZK,V309A,2.418965517241336,0.0,0.0030764409292788,0.0021336199122482,2.682183908045929,0.0,-0.0033687853795725,0.0018122211874322,2.768965517241449,4.440892098500626e-16,-0.30456069873253,0.0
3SZK,Y322=,0.0,0.0,,,-5.2273000742767785e-14,0.4434628743359078,-0.0605154286013307,0.0006255485191604,-1.5680946124918556e-13,0.0009753196981652,-0.1175503031635835,0.0037660145356111
3SZK,Y322A,3.2237931034482785,0.001462979547285,1.6256467041636624,0.0163206323912951,3.8757471264366834,0.4518205565257754,2.023184947654004,0.001549574668494,2.724827586206755,0.0,1.1639139999624604,0.0
3SZK,Y323=,5.2273000742767785e-14,0.0831804384150514,,,-5.2273000742767785e-14,0.0842407198271413,-0.0980149065985799,0.0057746668328682,4.625929269271485e-18,0.0555056983311767,-0.0515870169448689,0.0127746440376646
3SZK,Y323A,3.816321839080538,0.0055052551792649,2.072541529148383,0.0068157053755331,4.037701149425305,0.0466193633763483,1.6386040328395746,0.0314109714181315,3.239195402298908,0.0186128832792504,1.969242635985566,0.0293736088774431
3SZK,D330=,0.0,0.0,,,0.0,0.0,-0.0140463691386998,0.0016670389720764,-5.226982041639516e-14,0.0007085533336832,-0.2820365697785203,0.0040884068448717
3SZK,D330A,0.7817241379309743,0.0,-0.0587374592296014,0.0,-1.088620689655225,0.0,0.0350729742144565,0.0,0.0093103448275489,0.0031394253526205,-0.2807934863194637,0.0012572813324553
3SZK,D333=,0.0,0.0042730184587532,,,0.0,0.0,-0.0054419229298156,0.0,-5.226980234635895e-14,0.000325106566055,-0.2969263743165586,0.0007456099199617
3SZK,D333A,0.2555172413793576,0.1461451651649896,-0.0014951676771958,0.001610874516132,0.7317241379309806,0.0,-0.0039599689809369,0.0,0.7075862068965458,0.0014448051827841,-0.2877599732939688,0.0002042909696751
3SZK,D402=,0.0,0.0,,,0.0,0.0,-0.1217547169986134,1.3877787807814457e-17,0.0,0.0,0.0069986412875644,0.003500339436877
3SZK,D402A,1.0279310344828352,0.0,0.0542691880002752,0.0021336199120264,1.556896551724094,0.0,0.4814322317433206,5.551115123125783e-17,1.0496551724139047,0.0,0.063132161923367,0.003500339436877
3SZK,D403=,0.0,0.0,,,0.0,0.0,-0.0003480070148432,0.0017191785976303,0.0,0.0,0.0045087750205029,0.0
3SZK,D403A,1.2168965517241368,0.0,0.0056630962533996,0.0,1.5558620689655764,2.220446049250313e-16,0.0062328879958244,0.001396515447696,1.1855172413793456,0.0,-0.0011553715170646,0.0
3SZK,E405=,0.0,0.0,,,5.226982041639516e-14,0.0050391517740387,-0.1278916497580442,0.0038971588007814,0.0,0.0,0.0060101249494113,0.0035003394370248
3SZK,E405A,0.6365517241379323,0.0,-0.0157921914613576,0.0021336199119525,0.5787356321839435,0.0058519181891395,-0.132462162724216,0.0047086160230771,0.6710344827587474,0.0,0.0024600066102323,0.0035003394368031
3SZK,E406=,0.0,0.0,,,-5.226980234635895e-14,0.000325106566055,-0.1339255201579864,0.0026350737560246,0.0,0.0,0.0092643631234395,0.0035003394368031
3SZK,E406A,1.6982758620688714,0.0,0.0076222395889623,0.0021336199119525,1.6580459770113585,0.0,-0.1202568074321444,0.0,1.7213793103448929,0.0,-0.0047698334465794,0.003500339436877
3SZK,F325=,0.0,0.0,,,1.5680931668889588e-13,0.0018462503912837,-0.0466915197006235,0.0082890184828089,-1.5680975036976485e-13,0.0372768385183445,-0.6249345274755828,0.0011715548599459
3SZK,F325A,1.7534482758621337,0.0004876598491195,0.5704575518789746,0.0279307342775842,2.552643678161034,0.0008127664151747,1.3902391266350838,0.0072790552627717,1.4718390804596468,0.0021131926793951,0.1885131205448613,0.0014726140042794
3SZK,F326=,0.0,0.0,,,0.0,0.0039114251786786,-0.0603036885005512,0.0043991268673643,0.0,0.0036601570868948,-0.661509080663689,0.0032809467037942
3SZK,F326A,4.125862068965568,0.0042513200020742,3.3029616808609465,0.0058910279166387,3.920459770115015,0.0076607276795211,3.2118282926470805,0.0051538292602952,3.889425287356292,0.013284691296994,2.5502673418917365,0.0022232969876182
3SZK,G404=,0.0,0.0,,,0.0,0.0,-0.130342755634078,0.0,0.0,0.0,-6.849297435486546e-05,0.0035003394366552
3SZK,G404A,1.386551724137995,0.0,-0.0223037384718224,0.0167869820297497,0.6951724137931298,0.0,-0.3295213120970308,0.0,1.438275862068904,0.0,-0.0193518254332309,0.0035003394367292
3SZK,H324=,-5.2270109536974495e-14,0.0172329481301106,,,-1.0453732786815569e-13,0.0807477604589311,-0.1358755474243533,0.0305039027687027,1.734723475976807e-18,0.0504166809976677,-0.3282995834226166,0.0213445943161526
3SZK,H324A,1.6095402298850754,0.0063395780381852,0.0650150120167507,0.0196684688967619,0.8732183908044647,0.0911242736094638,-0.2164381345135385,0.0044279388476924,1.2520689655172448,0.0561693925602162,-0.351045480601897,0.0016464481880238
3SZK,K338=,0.0,0.0,,,0.0,0.0,-0.0038443192734748,0.0,0.0,0.0,0.0024751137920477,0.0035003394368031
3SZK,K338A,1.1989655172413316,0.0,5.331520665565442e-12,0.0,0.4417241379310169,5.551115123125783e-17,-0.0038443192223549,4.336808689942021e-19,0.5431034482757994,0.0,0.0024751137674287,0.0035003394368031
3SZK,K339=,0.0,0.0,,,0.0,0.0,-0.0025628794931216,0.0018122294805927,0.0,0.0,1.0506231899790724e-11,1.6155871338926322e-27
3SZK,K339A,0.8886206896552502,0.0,-0.007343973999463,0.0167868073414458,0.7582758620689893,0.0,-0.0012814397315332,0.0018122294805188,0.5686206896551336,0.0,3.2929980581433606e-11,0.0
3SZK,N317=,0.0,0.0,,,5.226982041639516e-14,0.0027054258151923,-0.0072551736965234,0.0039274301350884,-1.0453906259163166e-13,0.0572545338713724,0.0210497747259758,0.0152756072816207
3SZK,N317A,0.9952873563218512,0.0016497356430327,-0.0077470473004346,0.0188514387501785,1.0345977011494487,0.0025339549063315,-0.0052401866306072,0.0011086216609003,1.032413793103288,0.0551055629476318,0.0309678764390276,0.0015515368537234
3SZK,N348=,1.045396046927179e-13,0.0006502131321101,,,5.226982041639516e-14,0.0016255328302754,-0.0079860588051104,0.0023185497359282,0.0,0.0,-0.3242074978851602,0.0046209617928279
3SZK,N348A,1.0173563218392505,0.0002815505451407,1.6053282956699642,0.008670267601718,0.5358620689655473,0.0027345694835039,0.0887050024480283,0.0012475725702379,0.7972413793104666,0.0,0.3706217315064496,0.0049321448964516
3SZK,Q321=,-5.227068777813315e-14,0.0956651965565642,,,0.0,0.0016971060988408,-0.0099284053716808,0.0038485096007496,1.5680975036976485e-13,0.0170820221744788,-0.1015639063565498,0.0230209915295228
3SZK,Q321A,1.239655172413724,0.009795099899014,0.1518103834849108,0.0126837958994508,1.0290804597700598,0.0883020495160913,0.0500749608821955,0.0062418924959097,-0.251839080459643,0.0869012648481414,-0.0477979948357841,0.0058816385246141
3SZK,S351=,-5.226978427632276e-14,0.0006502131321101,,,0.0,0.0,-0.0102879718799848,0.0019758003357823,0.0,0.0,0.0028856942042003,0.003500339436877
3SZK,S351A,0.075287356321862,0.0004876598491195,-0.2269333729825235,0.000524579523218,0.3658620689655687,0.0336485295874782,-0.163351323815617,0.0022634672430267,0.2720689655173154,0.0,-0.1467462980516412,0.0
3SZK,T320=,0.0,0.0,,,0.0,0.0,-0.0003846925026915,0.0017408230875583,5.226982041639516e-14,0.0018318824656275,-0.0740956127136651,0.0021040781610003
3SZK,T320A,1.5296551724138443,2.220446049250313e-16,0.0970851732750063,1.3877787807814457e-17,1.3675862068966722,0.0,0.0934435519693893,0.0019556202638758,1.3839080459770077,2.220446049250313e-16,-0.0559039566286597,0.0
3SZK,T352=,0.0,0.0,,,5.227068777813315e-14,0.0342987427196623,-0.111370697841371,0.0037618477750303,0.0,0.0,0.0058763833371342,0.0035003380113907
3SZK,T352A,1.6668965517240804,0.0009753196981652,1.2438158294492696,0.0018609062212824,0.5112643678161288,0.0295846975117526,-0.1669092644757236,0.0068161854664802,1.427931034482785,0.0,1.346679291728394,0.0
3SZK,V309=,0.0,0.0,,,-1.807003620809174e-20,0.0009050583762885,-0.0027029551862226,0.0017663248524995,0.0,0.0,-0.2970788883992319,0.0
3SZK,V309A,2.418965517241336,0.0,0.0030764409292788,0.0021336199122482,2.682183908045929,0.0,-0.0033687853795725,0.0018122211874322,2.768965517241449,4.440892098500626e-16,-0.30456069873253,0.0
3SZK,Y322=,0.0,0.0,,,-5.2273000742767785e-14,0.4434628743359078,-0.0605154286013307,0.0006255485191604,-1.5680946124918556e-13,0.0009753196981652,-0.1175503031635835,0.0037660145356111
3SZK,Y322A,3.2237931034482785,0.001462979547285,1.6256467041636624,0.0163206323912951,3.8757471264366834,0.4518205565257754,2.023184947654004,0.001549574668494,2.724827586206755,0.0,1.1639139999624604,0.0
3SZK,Y323=,5.2273000742767785e-14,0.0831804384150514,,,-5.2273000742767785e-14,0.0842407198271413,-0.0980149065985799,0.0057746668328682,4.625929269271485e-18,0.0555056983311767,-0.0515870169448689,0.0127746440376646
3SZK,Y323A,3.816321839080538,0.0055052551792649,2.072541529148383,0.0068157053755331,4.037701149425305,0.0466193633763483,1.6386040328395746,0.0314109714181315,3.239195402298908,0.0186128832792504,1.969242635985566,0.0293736088774431