diff --git a/pygmt/params/frame.py b/pygmt/params/frame.py
new file mode 100644
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+++ b/pygmt/params/frame.py
@@ -0,0 +1,171 @@
+"""
+The Axes, Axis, and Frame classes for specifying the frame.
+"""
+
+import dataclasses
+from typing import Any, Literal
+
+from pygmt.alias import Alias
+from pygmt.params.base import BaseParam
+
+
+@dataclasses.dataclass(repr=False)
+class Axes(BaseParam):
+    """
+    Class for specifying the frame of a plot.
+
+    Attributes
+    ----------
+    axes
+        Specify which axes to draw and their attributes.
+    fill
+        Fill for the interior of the canvas [Default is no fill]. This also sets fill
+        for the two back-walls in 3-D plots.
+    title
+        The title string centered above the plot frame [Default is no title].
+    subtitle
+        The subtitle string beneath the title [Default is no subtitle]. This requires
+        ``title`` to be set.
+
+    Examples
+    --------
+    >>> from pygmt.params import Axes
+    >>> str(Axes("WSen", title="My Plot Title", fill="lightred"))
+    'WSen+glightred+tMy Plot Title'
+    """
+
+    axes: str | None = None
+    fill: str | None = None
+    title: str | None = None
+    subtitle: str | None = None
+
+    @property
+    def _aliases(self):
+        return [
+            Alias(self.axes, name="axes"),
+            Alias(self.fill, name="fill", prefix="+g"),
+            Alias(self.title, name="title", prefix="+t"),
+            Alias(self.subtitle, name="subtitle", prefix="+s"),
+        ]
+
+
+@dataclasses.dataclass(repr=False)
+class Axis(BaseParam):
+    """
+    Class for setting up one axis of a plot.
+
+    Attributes
+    ----------
+    interval
+        Intervals for annotations and major tick spacing, minor tick spacing, and/or
+        grid line spacing.
+    angle
+        Plot slanted annotations (for Cartesian plots only), where *angle* is measured
+        with respect to the horizontal and must be in the -90 <= *angle* <= 90 range.
+        Default is normal (i.e., ``angle=90``) for y-axis and parallel (i.e.,
+        ``angle=0``) for x-axis annotations. These defaults can be changed via
+        :gmt-term:`MAP_ANNOT_ORTHO`.
+    skip_edge
+        Skip annotations that fall exactly at the ends of the axis. Choose from ``left``
+        or ``right`` to skip only the lower or upper annotation, respectively, or
+        ``True`` to skip both.
+    fancy
+        Give fancy annotations with W|E|S|N suffixes encoding the sign (for geographic
+        axes only).
+    label/hlabel
+        Add a label to the axis (for Cartesian plots only). The label is placed parallel
+        to the axis by default; use **hlabel** to force a horizontal label for y-axis,
+        which is useful for very short labels.
+    alt_label/alt_hlabel
+        Add an alternate label for the right or upper axes. The label is placed parallel
+        to the axis by default; use **alt_hlabel** to force a horizontal label for
+        y-axis, which is useful for very short labels. [For Cartesian plots only].
+    prefix
+        Add a leading text prefix for axis annotation (e.g., dollar sign for plots
+        related to money) (for Cartesian plots only). For geographic maps the addition
+        of degree symbols, etc. is automatic and controlled by
+        :gmt-term:`FORMAT_GEO_MAP`.
+    unit
+        Append a unit to the annotations (for Cartesian plots only). For geographic maps
+        the addition of degree symbols, etc. is automatic and controlled by
+        :gmt-term:`FORMAT_GEO_MAP`.
+
+    Examples
+    --------
+    >>> from pygmt.params import Axis
+    >>> str(Axis(10, angle=30, label="X axis", unit="km"))
+    '10+a30+lX axis+ukm'
+    """
+
+    interval: float | str  # How to make it more Pythonic?
+    angle: float | None = None
+    skip_edge: Literal["left", "right"] | bool = False
+    fancy: bool = False
+    label: str | None = None
+    hlabel: str | None = None
+    alt_label: str | None = None
+    alt_hlabel: str | None = None
+    prefix: str | None = None
+    unit: str | None = None
+
+    @property
+    def _aliases(self):
+        return [
+            Alias(self.interval, name="interval"),
+            Alias(self.angle, name="angle", prefix="+a"),
+            Alias(
+                self.skip_edge,
+                name="skip_edge",
+                prefix="+e",
+                mapping={True: True, "left": "l", "right": "r"},
+            ),
+            Alias(self.fancy, name="fancy", prefix="+f"),
+            Alias(self.label, name="label", prefix="+l"),
+            Alias(self.hlabel, name="hlabel", prefix="+L"),
+            Alias(self.alt_label, name="alt_label", prefix="+s"),
+            Alias(self.alt_hlabel, name="alt_hlabel", prefix="+S"),
+            Alias(self.unit, name="unit", prefix="+u"),
+        ]
+
+
+@dataclasses.dataclass(repr=False)
+class Frame(BaseParam):
+    """
+    Class for setting up the frame of a plot.
+
+    >>> from pygmt.alias import AliasSystem, Alias
+    >>> from pygmt.params import Frame, Axes, Axis
+    >>> frame = Frame(
+    ...     axes=Axes("WSen", title="My Plot Title", fill="lightred"),
+    ...     xaxis=Axis(10, angle=30, label="X axis", unit="km"),
+    ... )
+    >>> def func(frame):
+    ...     alias = AliasSystem(B=Alias(frame))
+    ...     return alias.kwdict
+    >>> dict(func(frame))
+    {'B': ['WSen+glightred+tMy Plot Title', 'x10+a30+lX axis+ukm']}
+    """
+
+    axes: Any = None
+    xaxis: Any = None
+    yaxis: Any = None
+    zaxis: Any = None
+
+    @property
+    def _aliases(self):
+        return [
+            Alias(self.axes),
+            Alias(self.xaxis, prefix="x"),
+            Alias(self.yaxis, prefix="y"),
+            Alias(self.zaxis, prefix="z"),
+        ]
+
+    def __iter__(self):
+        """
+        Iterate over the aliases of the class.
+
+        Yields
+        ------
+        The value of each alias in the class. None are excluded.
+        """
+        yield from (alias._value for alias in self._aliases if alias._value is not None)