diff --git a/src/main/java/com/google/devtools/build/lib/skyframe/toolchains/ToolchainResolutionFunction.java b/src/main/java/com/google/devtools/build/lib/skyframe/toolchains/ToolchainResolutionFunction.java
index df1d1ebfb1d803..b0f1e618115177 100644
--- a/src/main/java/com/google/devtools/build/lib/skyframe/toolchains/ToolchainResolutionFunction.java
+++ b/src/main/java/com/google/devtools/build/lib/skyframe/toolchains/ToolchainResolutionFunction.java
@@ -50,6 +50,7 @@
 import java.util.Optional;
 import java.util.SequencedSet;
 import java.util.Set;
+import java.util.regex.Pattern;
 import javax.annotation.Nullable;
 
 /**
@@ -392,10 +393,24 @@ protected Code getDetailedCode() {
 
     private static String getMessage(
         PlatformInfo targetPlatformInfo, SequencedSet<ToolchainTypeInfo> missingToolchainTypes) {
+      // All characters with special meaning anywhere in a regex (':' for example is only special within brackets).
+      List<Character> regexSpecialChars = "+.|([{^$?\\*".codePoints()
+          .mapToObj(c -> (char) c)
+          .toList();
       ImmutableList<String> labelStrings =
           missingToolchainTypes.stream()
               .map(ToolchainTypeInfo::typeLabel)
               .map(Label::toString)
+              .map(label -> {
+                // Regex-quote if label contains special characters.
+                for (char c : regexSpecialChars) {
+                  if (label.indexOf(c) >= 0) {
+                    return Pattern.quote(label);
+                  }
+                }
+                
+                return label;
+              })
               .collect(toImmutableList());
       ImmutableList<String> missingToolchainRows =
           missingToolchainTypes.stream()
diff --git a/src/test/java/com/google/devtools/build/lib/skyframe/toolchains/BUILD b/src/test/java/com/google/devtools/build/lib/skyframe/toolchains/BUILD
index a4386fb222c4ff..91367dbff46603 100644
--- a/src/test/java/com/google/devtools/build/lib/skyframe/toolchains/BUILD
+++ b/src/test/java/com/google/devtools/build/lib/skyframe/toolchains/BUILD
@@ -139,11 +139,13 @@ java_test(
         "//src/main/java/com/google/devtools/build/lib/analysis:platform_options",
         "//src/main/java/com/google/devtools/build/lib/analysis/config:build_options",
         "//src/main/java/com/google/devtools/build/lib/analysis/config:toolchain_type_requirement",
+        "//src/main/java/com/google/devtools/build/lib/analysis/platform",
         "//src/main/java/com/google/devtools/build/lib/cmdline",
         "//src/main/java/com/google/devtools/build/lib/skyframe/config",
         "//src/main/java/com/google/devtools/build/lib/skyframe/toolchains:constraint_value_lookup_util",
         "//src/main/java/com/google/devtools/build/lib/skyframe/toolchains:platform_lookup_util",
         "//src/main/java/com/google/devtools/build/lib/skyframe/toolchains:toolchain_context_key",
+        "//src/main/java/com/google/devtools/build/lib/skyframe/toolchains:toolchain_resolution_function",
         "//src/main/java/com/google/devtools/build/lib/skyframe/toolchains:toolchain_type_lookup_util",
         "//src/main/java/com/google/devtools/build/lib/skyframe/toolchains:unloaded_toolchain_context",
         "//src/main/java/com/google/devtools/build/skyframe",
diff --git a/src/test/java/com/google/devtools/build/lib/skyframe/toolchains/ToolchainResolutionFunctionTest.java b/src/test/java/com/google/devtools/build/lib/skyframe/toolchains/ToolchainResolutionFunctionTest.java
index e1a6bf79e6f642..cd1dfb3feaabc7 100644
--- a/src/test/java/com/google/devtools/build/lib/skyframe/toolchains/ToolchainResolutionFunctionTest.java
+++ b/src/test/java/com/google/devtools/build/lib/skyframe/toolchains/ToolchainResolutionFunctionTest.java
@@ -18,9 +18,11 @@
 import static com.google.devtools.build.skyframe.EvaluationResultSubjectFactory.assertThatEvaluationResult;
 
 import com.google.common.collect.ImmutableList;
-import com.google.devtools.build.lib.analysis.PlatformOptions;
 import com.google.devtools.build.lib.analysis.config.BuildOptions;
 import com.google.devtools.build.lib.analysis.config.ToolchainTypeRequirement;
+import com.google.devtools.build.lib.analysis.platform.PlatformInfo;
+import com.google.devtools.build.lib.analysis.platform.ToolchainTypeInfo;
+import com.google.devtools.build.lib.analysis.PlatformOptions;
 import com.google.devtools.build.lib.cmdline.Label;
 import com.google.devtools.build.lib.rules.platform.ToolchainTestCase;
 import com.google.devtools.build.lib.skyframe.config.BuildConfigurationKey;
@@ -30,6 +32,7 @@
 import com.google.devtools.build.lib.skyframe.util.SkyframeExecutorTestUtils;
 import com.google.devtools.build.skyframe.EvaluationResult;
 import com.google.devtools.build.skyframe.SkyKey;
+import java.util.LinkedHashSet;
 import org.junit.Test;
 import org.junit.runner.RunWith;
 import org.junit.runners.JUnit4;
@@ -396,6 +399,29 @@ public void resolve_mandatory_missing() throws Exception {
 """);
   }
 
+  @Test
+  public void unresolved_toolchain_message_regex_quotes() throws Exception {
+    PlatformInfo platformInfo = PlatformInfo.builder()
+        .setLabel(Label.parseCanonicalUnchecked("//platforms:test_platform"))
+        .build();
+    ToolchainTypeInfo toolchainTypeInfo = ToolchainTypeInfo.create(
+        Label.parseCanonicalUnchecked("@@repo+//toolchain:test_toolchain"));
+    LinkedHashSet<ToolchainTypeInfo> missingToolchainTypes = new LinkedHashSet<>();
+    missingToolchainTypes.add(toolchainTypeInfo);
+
+    var exception = new ToolchainResolutionFunction.UnresolvedToolchainsException(platformInfo, missingToolchainTypes);
+
+    assertThat(exception)
+        .hasMessageThat()
+        .isEqualTo(
+"""
+No matching toolchains found for types:
+  @@repo+//toolchain:test_toolchain
+To debug, rerun with --toolchain_resolution_debug='\\Q@@repo+//toolchain:test_toolchain\\E'
+"""
+        );
+  }
+
   @Test
   public void resolve_mandatory_missing_customPlatformMessage() throws Exception {
     scratch.appendFile(