Gene Signatures Origin

[jcasadogp]

Hi,

I am working with XCell and I am curious about the origin and how you obtained the gene signatures.

If I am correct, there are available on the xCell.data.rda object you have on the repository and then on xCell.data$signatures[[XXX]]@geneIds, replacing XXX by each signature, e.g., "aDC%HPCA%1.txt". I wanted to know where this data comes from and what are the differences between HPCA and IRIS origin.

Thank you in advanced!

Julia

[dviraran]

Hi,

All this information can be found in the paper: https://genomebiology.biomedcentral.com/articles/10.1186/s13059-017-1349-1

Best,
Dvir