using CNVKit standard pipeline I created :
cnvkit.py batch bam/*.bam --drop-low-coverage -p 45 -r Reference.cnn -d sample -m amplicon
cnvkit.py call -m clonal sample.cns --purity 0.45 -x female -y -o sample.call.cns
Now I want to use PureCN to estimate tumor ploidy what is best possible pipeline for this ?
@lbeltrame @chapmanb @lima1 @jwokaty @dtenenba Please help