HiCPro iced matrices to cooler #288
Description
Hello,
I have iced matrix genereated by HiC-Pro. when I run hicpro2higlass from HiC-pro on iced matrix, I can covbert the iced matrix to cooler format. however, there is no weight column in the cooler file. How can I add the weight calculated by ICE to the cooler file?
another question is that I convert the raw matrix generated by HiC-Pro to cooler format.
for example I have 2 cooler file, one is the 4000kb.cool, and the other is the 4000kb.mcool. why the 4000kb.cool does not have weight column, while the 4000kb.mcool does have the weight? please see the attached.
Best,