diff --git a/.github/workflows/ci.yaml b/.github/workflows/ci.yaml
index 6bb08b61..62a39d15 100644
--- a/.github/workflows/ci.yaml
+++ b/.github/workflows/ci.yaml
@@ -25,14 +25,12 @@ jobs:
       OE_LICENSE: ${{ github.workspace }}/oe_license.txt
 
     strategy:
-      fail-fast: false
       matrix:
         os:
           - ubuntu-latest
           - macos-latest
         python-version:
-          - "3.11"
-          - "3.12"
+          - "3.13"
         pymbar-version:
           - "3.1"
         pydantic-version:
diff --git a/devtools/conda-envs/test_env.yaml b/devtools/conda-envs/test_env.yaml
index 1c6da24d..ce114192 100644
--- a/devtools/conda-envs/test_env.yaml
+++ b/devtools/conda-envs/test_env.yaml
@@ -19,7 +19,8 @@ dependencies:
   - pint >=0.21,<0.25
 
     # Standard dependencies
-  - openff-toolkit >=0.14.3
+  - openff-toolkit ~=0.16.0
+  - openff-interchange ~=0.4.0
   - openmm
   - pymbar
   - dask >=2.7.0