diff --git a/inference/core/interfaces/webrtc_worker/entities.py b/inference/core/interfaces/webrtc_worker/entities.py
index 3d2a0e0136..cfee2840ce 100644
--- a/inference/core/interfaces/webrtc_worker/entities.py
+++ b/inference/core/interfaces/webrtc_worker/entities.py
@@ -39,6 +39,9 @@ class WebRTCWorkerRequest(BaseModel):
     data_output: Optional[List[str]] = Field(default=None)
     declared_fps: Optional[float] = None
     rtsp_url: Optional[str] = None
+    use_data_channel_frames: bool = (
+        False  # When True, expect frames via data channel instead of media track
+    )
     processing_timeout: Optional[int] = WEBRTC_MODAL_FUNCTION_TIME_LIMIT
     processing_session_started: Optional[datetime.datetime] = None
     requested_plan: Optional[str] = "webrtc-gpu-small"
diff --git a/inference/core/interfaces/webrtc_worker/webrtc.py b/inference/core/interfaces/webrtc_worker/webrtc.py
index b899d510be..a990d528c4 100644
--- a/inference/core/interfaces/webrtc_worker/webrtc.py
+++ b/inference/core/interfaces/webrtc_worker/webrtc.py
@@ -2,8 +2,11 @@
 import datetime
 import json
 import logging
+import struct
 from typing import Any, Callable, Dict, List, Optional, Tuple
 
+import cv2
+import numpy as np
 from aiortc import (
     RTCConfiguration,
     RTCDataChannel,
@@ -60,6 +63,113 @@
 
 logging.getLogger("aiortc").setLevel(logging.WARNING)
 
+# WebRTC data channel chunking configuration
+CHUNK_SIZE = 48 * 1024  # 48KB - safe for all WebRTC implementations
+
+
+def create_chunked_binary_message(
+    frame_id: int, chunk_index: int, total_chunks: int, payload: bytes
+) -> bytes:
+    """Create a binary message with standard 12-byte header.
+
+    Format: [frame_id: 4][chunk_index: 4][total_chunks: 4][payload: N]
+    All integers are uint32 little-endian.
+    """
+    header = struct.pack("<III", frame_id, chunk_index, total_chunks)
+    return header + payload
+
+
+def parse_chunked_binary_message(message: bytes) -> Tuple[int, int, int, bytes]:
+    """Parse a binary message with standard 12-byte header.
+
+    Returns: (frame_id, chunk_index, total_chunks, payload)
+    """
+    if len(message) < 12:
+        raise ValueError(f"Message too short: {len(message)} bytes (expected >= 12)")
+
+    frame_id, chunk_index, total_chunks = struct.unpack("<III", message[0:12])
+    payload = message[12:]
+    return frame_id, chunk_index, total_chunks, payload
+
+
+class ChunkReassembler:
+    """Helper to reassemble chunked binary messages."""
+
+    def __init__(self):
+        self._chunks: Dict[int, Dict[int, bytes]] = (
+            {}
+        )  # {frame_id: {chunk_index: data}}
+        self._total: Dict[int, int] = {}  # {frame_id: total_chunks}
+
+    def add_chunk(
+        self, frame_id: int, chunk_index: int, total_chunks: int, chunk_data: bytes
+    ) -> Optional[bytes]:
+        """Add a chunk and return complete payload if all chunks received.
+
+        Returns:
+            Complete reassembled payload bytes if all chunks received, None otherwise.
+        """
+        # Initialize buffers for new frame
+        if frame_id not in self._chunks:
+            self._chunks[frame_id] = {}
+            self._total[frame_id] = total_chunks
+
+        # Store chunk
+        self._chunks[frame_id][chunk_index] = chunk_data
+
+        # Check if all chunks received
+        if len(self._chunks[frame_id]) >= total_chunks:
+            # Reassemble in order
+            complete_payload = b"".join(
+                self._chunks[frame_id][i] for i in range(total_chunks)
+            )
+
+            # Clean up
+            del self._chunks[frame_id]
+            del self._total[frame_id]
+
+            return complete_payload
+
+        return None
+
+
+def send_chunked_data(
+    data_channel: RTCDataChannel,
+    frame_id: int,
+    payload_bytes: bytes,
+    chunk_size: int = CHUNK_SIZE,
+) -> None:
+    """Send payload via data channel, automatically chunking if needed.
+
+    Args:
+        data_channel: RTCDataChannel to send on
+        frame_id: Frame identifier
+        payload_bytes: Data to send (JPEG, JSON UTF-8, etc.)
+        chunk_size: Maximum chunk size (default 48KB)
+    """
+    if data_channel.readyState != "open":
+        logger.warning(f"Cannot send response for frame {frame_id}, channel not open")
+        return
+
+    total_chunks = (
+        len(payload_bytes) + chunk_size - 1
+    ) // chunk_size  # Ceiling division
+
+    if frame_id % 100 == 1:
+        logger.info(
+            f"Sending response for frame {frame_id}: {total_chunks} chunk(s), {len(payload_bytes)} bytes"
+        )
+
+    for chunk_index in range(total_chunks):
+        start = chunk_index * chunk_size
+        end = min(start + chunk_size, len(payload_bytes))
+        chunk_data = payload_bytes[start:end]
+
+        message = create_chunked_binary_message(
+            frame_id, chunk_index, total_chunks, chunk_data
+        )
+        data_channel.send(message)
+
 
 class RTCPeerConnectionWithLoop(RTCPeerConnection):
     def __init__(
@@ -91,6 +201,7 @@ def __init__(
         declared_fps: float = 30,
         termination_date: Optional[datetime.datetime] = None,
         terminate_event: Optional[asyncio.Event] = None,
+        use_data_channel_frames: bool = False,
     ):
         self._loop = asyncio_loop
         self._termination_date = termination_date
@@ -101,6 +212,11 @@ def __init__(
         self._received_frames = 0
         self._declared_fps = declared_fps
         self._stop_processing = False
+        self.use_data_channel_frames = use_data_channel_frames
+        self._data_frame_queue: "asyncio.Queue[Optional[VideoFrame]]" = asyncio.Queue()
+        self._chunk_reassembler = (
+            ChunkReassembler()
+        )  # For reassembling inbound frame chunks
 
         self.has_video_track = has_video_track
         self.stream_output = stream_output
@@ -185,7 +301,9 @@ async def _send_data_output(
         )
 
         if self._data_mode == DataOutputMode.NONE:
-            self.data_channel.send(json.dumps(webrtc_output.model_dump()))
+            # Even empty responses use binary protocol
+            json_bytes = json.dumps(webrtc_output.model_dump()).encode("utf-8")
+            send_chunked_data(self.data_channel, self._received_frames, json_bytes)
             return
 
         if self._data_mode == DataOutputMode.ALL:
@@ -216,11 +334,55 @@ async def _send_data_output(
                 webrtc_output.errors.append(f"{field_name}: {e}")
                 serialized_outputs[field_name] = {"__serialization_error__": str(e)}
 
-        # Only set serialized_output_data if we have data to send
+        # Set serialized outputs
         if serialized_outputs:
             webrtc_output.serialized_output_data = serialized_outputs
 
-        self.data_channel.send(json.dumps(webrtc_output.model_dump(mode="json")))
+        # Send using binary chunked protocol
+        json_bytes = json.dumps(webrtc_output.model_dump(mode="json")).encode("utf-8")
+        send_chunked_data(self.data_channel, self._received_frames, json_bytes)
+
+    async def _handle_data_channel_frame(self, message: bytes) -> None:
+        """Handle incoming binary frame chunk from upstream_frames data channel.
+
+        Uses standard binary protocol with 12-byte header + JPEG chunk payload.
+        """
+        try:
+            # Parse message
+            frame_id, chunk_index, total_chunks, jpeg_chunk = (
+                parse_chunked_binary_message(message)
+            )
+
+            # Add chunk and check if complete
+            jpeg_bytes = self._chunk_reassembler.add_chunk(
+                frame_id, chunk_index, total_chunks, jpeg_chunk
+            )
+
+            if jpeg_bytes is None:
+                # Still waiting for more chunks
+                return
+
+            # All chunks received - decode and queue frame
+            if frame_id % 100 == 1:
+                logger.info(
+                    f"Received frame {frame_id}: {total_chunks} chunk(s), {len(jpeg_bytes)} bytes JPEG"
+                )
+
+            nparr = np.frombuffer(jpeg_bytes, np.uint8)
+            np_image = cv2.imdecode(nparr, cv2.IMREAD_COLOR)
+
+            if np_image is None:
+                logger.error(f"Failed to decode JPEG for frame {frame_id}")
+                return
+
+            video_frame = VideoFrame.from_ndarray(np_image, format="bgr24")
+            await self._data_frame_queue.put((frame_id, video_frame))
+
+            if frame_id % 100 == 1:
+                logger.info(f"Queued frame {frame_id}")
+
+        except Exception as e:
+            logger.error(f"Error handling frame chunk: {e}", exc_info=True)
 
     async def process_frames_data_only(self):
         """Process frames for data extraction only, without video track output.
@@ -232,24 +394,37 @@ async def process_frames_data_only(self):
             av_logging.set_libav_level(av_logging.ERROR)
             self._av_logging_set = True
 
-        logger.info("Starting data-only frame processing")
+        logger.info(
+            f"Starting data-only frame processing (use_data_channel_frames={self.use_data_channel_frames})"
+        )
 
         try:
-            while (
-                self.track
-                and self.track.readyState != "ended"
-                and not self._stop_processing
-            ):
+            while not self._stop_processing:
                 if self._check_termination():
                     break
 
-                # Drain queue if using PlayerStreamTrack (RTSP)
-                if isinstance(self.track, PlayerStreamTrack):
-                    while self.track._queue.qsize() > 30:
-                        self.track._queue.get_nowait()
+                # Get frame from appropriate source
+                if self.use_data_channel_frames:
+                    # Wait for frame from data channel queue
+                    item = await self._data_frame_queue.get()
+                    if item is None:
+                        logger.info("Received stop signal from data channel")
+                        break
+                    frame_id, frame = item
+                    self._received_frames = frame_id
+                else:
+                    # Get frame from media track (existing behavior)
+                    if not self.track or self.track.readyState == "ended":
+                        break
+
+                    # Drain queue if using PlayerStreamTrack (RTSP)
+                    if isinstance(self.track, PlayerStreamTrack):
+                        while self.track._queue.qsize() > 30:
+                            self.track._queue.get_nowait()
+
+                    frame = await self.track.recv()
+                    self._received_frames += 1
 
-                frame: VideoFrame = await self.track.recv()
-                self._received_frames += 1
                 frame_timestamp = datetime.datetime.now()
 
                 workflow_output, _, errors = await self._process_frame_async(
@@ -372,6 +547,7 @@ def __init__(
         declared_fps: float = 30,
         termination_date: Optional[datetime.datetime] = None,
         terminate_event: Optional[asyncio.Event] = None,
+        use_data_channel_frames: bool = False,
         *args,
         **kwargs,
     ):
@@ -387,6 +563,7 @@ def __init__(
             declared_fps=declared_fps,
             termination_date=termination_date,
             terminate_event=terminate_event,
+            use_data_channel_frames=use_data_channel_frames,
             model_manager=model_manager,
         )
 
@@ -531,6 +708,7 @@ async def init_rtc_peer_connection_with_loop(
                 declared_fps=webrtc_request.declared_fps,
                 termination_date=termination_date,
                 terminate_event=terminate_event,
+                use_data_channel_frames=webrtc_request.use_data_channel_frames,
             )
         else:
             # No video track - use base VideoFrameProcessor
@@ -545,6 +723,7 @@ async def init_rtc_peer_connection_with_loop(
                 declared_fps=webrtc_request.declared_fps,
                 termination_date=termination_date,
                 terminate_event=terminate_event,
+                use_data_channel_frames=webrtc_request.use_data_channel_frames,
             )
     except (
         ValidationError,
@@ -679,6 +858,23 @@ async def on_connectionstatechange():
     def on_datachannel(channel: RTCDataChannel):
         logger.info("Data channel '%s' received", channel.label)
 
+        # Handle upstream frames channel (client sending frames to server)
+        if channel.label == "upstream_frames":
+            logger.info(
+                "Upstream frames channel established, starting data-only processing"
+            )
+
+            @channel.on("message")
+            def on_frame_message(message):
+                asyncio.create_task(video_processor._handle_data_channel_frame(message))
+
+            # Start processing immediately since we won't get a media track
+            if webrtc_request.use_data_channel_frames and not should_send_video:
+                asyncio.create_task(video_processor.process_frames_data_only())
+
+            return
+
+        # Handle inference control channel (bidirectional communication)
         @channel.on("message")
         def on_message(message):
             logger.info("Data channel message received: %s", message)