diff --git a/src/uproot_browser/plot.py b/src/uproot_browser/plot.py
index bb5fc1b..52a3724 100644
--- a/src/uproot_browser/plot.py
+++ b/src/uproot_browser/plot.py
@@ -50,8 +50,9 @@ def plot(tree: Any) -> None:
     raise RuntimeError(msg)
 
 
-@plot.register
-def plot_branch(tree: uproot.TBranch) -> None:
+# Simpler in Python 3.11+
+@plot.register(uproot.TBranch)
+def plot_branch(tree: uproot.TBranch | uproot.models.RNTuple.RField) -> None:
     """
     Plot a single tree branch.
     """
@@ -69,6 +70,10 @@ def plot_branch(tree: uproot.TBranch) -> None:
     plt.title(make_hist_title(tree, histogram))
 
 
+if hasattr(uproot.models, "RNTuple") and hasattr(uproot.models.RNTuple, "RField"):
+    plot.register(uproot.models.RNTuple.RField)(plot_branch)  # type: ignore[no-untyped-call]
+
+
 @plot.register
 def plot_hist(tree: uproot.behaviors.TH1.Histogram) -> None:
     """
diff --git a/src/uproot_browser/tree.py b/src/uproot_browser/tree.py
index 946a9c6..414d77b 100644
--- a/src/uproot_browser/tree.py
+++ b/src/uproot_browser/tree.py
@@ -57,6 +57,15 @@ def _(item: uproot.behaviors.TBranch.HasBranches) -> bool:
     return len(item.branches) > 0
 
 
+if hasattr(uproot.behaviors, "RNTuple") and hasattr(
+    uproot.behaviors.RNTuple, "HasFields"
+):
+
+    @is_dir.register
+    def _(item: uproot.behaviors.RNTuple.HasFields) -> bool:
+        return len(item.keys()) > 0
+
+
 def get_children(item: Mapping[str, Any]) -> set[str]:
     return {
         key.split(";")[0]
@@ -152,8 +161,11 @@ def _process_item_tfile(
     )
 
 
-@process_item.register
-def _process_item_ttree(uproot_object: uproot.TTree) -> MetaDict:
+# Python 3.11 can just use `|` directly for register
+@process_item.register(uproot.TTree)
+def _process_item_ttree(
+    uproot_object: uproot.TTree | uproot.behaviors.RNTuple.RNTuple,
+) -> MetaDict:
     """
     Given an tree, return a rich.tree.Tree output.
     """
@@ -169,6 +181,12 @@ def _process_item_ttree(uproot_object: uproot.TTree) -> MetaDict:
     )
 
 
+if hasattr(uproot.behaviors, "RNTuple") and hasattr(
+    uproot.behaviors.RNTuple, "HasFields"
+):
+    process_item.register(uproot.behaviors.RNTuple.RNTuple)(_process_item_ttree)  # type: ignore[no-untyped-call]
+
+
 @process_item.register
 def _process_item_tbranch(uproot_object: uproot.TBranch) -> MetaDict:
     """