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Novartis Open Source Initiative

Hosts open source projects for Novartis R&D. Details and instructions can be found on go/OSI (from Novartis network).

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Repositories

Showing 10 of 101 repositories
  • tinydenseR Public

    tinydenseR is a landmark-based platform for single cell data analysis that identifies differentially abundant cell types and differentially expressed features, including subtle within-cluster state changes. Modeling samples as replicates, tinydenseR enhances analytic efficiency and reproducibility while preserving the richness of single cell data

    Novartis/tinydenseR’s past year of commit activity
    R 2 1 0 0 Updated Dec 10, 2025
  • singleCellComic Public

    singeCellComic is an interactive Shiny application designed to teach the fundamental concepts of single-cell RNA sequencing (scRNA-seq) analysis through a fun, story-driven, and visual narrative.

    Novartis/singleCellComic’s past year of commit activity
    R 1 MIT 0 0 0 Updated Dec 9, 2025
  • UNIQUE Public

    A Python library for benchmarking uncertainty estimation and quantification methods for Machine Learning models predictions.

    Novartis/UNIQUE’s past year of commit activity
    Python 40 BSD-3-Clause 6 0 2 Updated Dec 8, 2025
  • torchsurv Public

    Deep survival analysis made easy

    Novartis/torchsurv’s past year of commit activity
    Python 169 MIT 13 8 1 Updated Dec 3, 2025
  • cellxgene-gateway Public

    Cellxgene Gateway allows you to use the Cellxgene Server provided by the Chan Zuckerberg Institute (https://github.com/chanzuckerberg/cellxgene) with multiple datasets.

    Novartis/cellxgene-gateway’s past year of commit activity
    Python 66 Apache-2.0 38 13 (1 issue needs help) 3 Updated Dec 3, 2025
  • subgroup_shrinkage Public

    Bayesian subgroup shrinkage estimation benchmark comparing various shrinkage models.

    Novartis/subgroup_shrinkage’s past year of commit activity
    R 0 GPL-3.0 1 0 0 Updated Dec 2, 2025
  • Pipeline_for_TES_AAV_LongReads Public

    This pipeline is designed for AAV integration site analysis using Target Enrichment Sequencing (TES) coupled with PacBio long-read sequencing. It enables the detection of integration site breakpoints and provides information on the structure of the integrated AAV vector genome to support the safety assessment of AAV-based gene therapies.

    Novartis/Pipeline_for_TES_AAV_LongReads’s past year of commit activity
    Jupyter Notebook 0 MIT 0 0 0 Updated Nov 26, 2025
  • attrib-path Public

    Parse a simplified JSONPath-like syntax

    Novartis/attrib-path’s past year of commit activity
    TypeScript 1 Apache-2.0 0 0 2 Updated Nov 18, 2025
  • bamdd Public

    Applied modelling in drug development: flexible Bayesian regression modelling in Stan via brms

    Novartis/bamdd’s past year of commit activity
    HTML 24 GPL-2.0 7 0 0 Updated Oct 21, 2025
  • slc-localization Public

    The codebase created to support the application of artificial intelligence for predicting the subcellular localization of solute carrier transporter (SLC) proteins. We developed an iterative method that harmonizes human annotations with AI-based model outputs.

    Novartis/slc-localization’s past year of commit activity
    Python 1 MIT 0 0 0 Updated Oct 20, 2025