Awesome AutoResearch

A curated list of AutoResearch tools and frameworks that can autonomously conduct research, design experiments, analyze data, write papers, and generate scientific discoveries.

AutoResearch represents a new paradigm in scientific discovery where AI systems can perform the complete research lifecycle - from hypothesis generation to peer review - with minimal or no human intervention. These systems leverage large language models and multi-agent frameworks to accelerate scientific progress across multiple domains.

Open-source Research Agents & Tools

End-to-End Research Systems

Autonomous systems that cover the full research lifecycle from ideation through experimentation and paper writing.

• AI-Scientist - First comprehensive system for fully automatic scientific discovery, enabling LLMs to autonomously generate ideas, run experiments, and write papers.
• AI-Scientist-v2 - Workshop-level automated scientific discovery via agentic tree search; builds on AI-Scientist with improved experimental control.
• AgentLaboratory - End-to-end autonomous research workflow using LLM agents to assist with literature reviews, experiments, and report writing.
• AI-Researcher - Autonomous scientific innovation system with dedicated research and paper agents for idea generation, experiment execution, and paper writing.
• ARIS - Lightweight Markdown-only research workflow with cross-model review loops, idea discovery, and experiment automation.
• auto-research - Autonomous generalist scientist framework for fully automated research agents from literature reviews to experiments and writing.
• autoresearch - Karpathy's autonomous overnight research loop where agents iteratively edit/train/evaluate a compact LLM setup under a fixed 5-minute experiment budget.
• AutoResearchClaw - Fully autonomous & self-evolving research from idea to paper using a multi-agent debate pipeline with self-healing and citation verification.
• Curie - AI-agent framework for automated and rigorous scientific experimentation with end-to-end automation from hypothesis formulation to result interpretation.
• nano-scientist - Budget-driven autonomous research agent that turns a topic into a technical report with a plan-execute-review loop and PDF output pipeline.
• OmniScientist - AI Scientist ecosystem covering idea generation, experiment design, and paper writing as a holistic blueprint for autonomous research.
• pi-autoresearch - Extension for the pi agent that enables autonomous experiment loops to benchmark ideas, keep improvements, and revert regressions.
• Virtual-Scientists - ACL 2025 project featuring many-heads multi-agent scientific idea generation for diverse hypothesis exploration.

Deep Research Agents

Research-focused agents for iterative retrieval, synthesis, and report generation on complex questions.

• open_deep_research - Fully open-source deep research agent with multi-model support, multi-search API, MCP integration, and built-in report generation.
• DeepResearch - Tongyi Deep Research — iterative retrieval-augmented research agent for complex multi-hop questions.

Experiment & Data Automation

Tools that automate experiment execution, data workflows, and closed-loop empirical research pipelines.

• agentic-data-scientist - Multi-agent framework for data science workflows with separated planning and execution phases.
• autora - Automated research assistant for closed-loop empirical research with autonomous experiment design and data analysis.
• Simply - Minimal JAX research codebase by Google DeepMind designed for agents to read code, propose ideas, run experiments, and iterate.

Scientific Writing & Skills

Frameworks and skill collections that support scientific writing, reasoning, and reusable research capabilities.

• claude-scientific-skills - Comprehensive collection of 140 ready-to-use scientific skills for Claude across biology, chemistry, medicine, and more.
• claude-scientific-writer - AI-powered scientific writing assistant for automated research paper generation and technical documentation.
• autoresearch-skill - Cross-platform LLM skill set (Claude Code/Codex/Gemini) that runs experiment-evaluate-iterate autoresearch loops from natural-language goals.
• Researcher - AI-powered research assistant for automated research workflows.

Learning & Tutorials

Educational resources for learning autonomous research concepts, tools, and practical workflows.

• learn-auto-research - Educational repository for learning and practicing autonomous research workflows.

Research Platforms

Integrated platforms that host AI agents for collaborative research, publishing, and scientific workflows.

• aiXiv - Multi-agent preprint server for human, AI and robot scientists with dual-track review and auto-agents ecosystem.

Benchmarks & Evaluation

Benchmarks and evaluation suites for measuring capabilities of autonomous research agents across tasks.

• aira-dojo - Meta FAIR's extensible AI research agent development and evaluation framework with isolated code execution.
• AIRS-Bench - Benchmark by Meta FAIR for quantifying end-to-end AI research abilities of LLM agents.
• DeepResearch Bench - Comprehensive benchmark and leaderboard for evaluating deep research agents.
• MLGym - Unified framework and benchmark by Meta FAIR for developing and evaluating AI research agents across ML tasks.

ResearchClaw & OpenClaw Ecosystem

Agent-native research tools built on or inspired by the OpenClaw framework, covering research platforms, IDEs, skill libraries, and multi-agent research pipelines.

Research Platforms & IDEs

OpenClaw-based platforms and IDE experiences for end-to-end scientific workflows and agent orchestration.

• Dr. Claw - AI research IDE with 100+ skills, structured dashboard (Survey → Ideation → Experiment → Publication), auto-research one-click execution, and multi-agent support.
• openclaw-agents - One-command setup for 9 specialized research agents with Paper Pipeline, Brainstorm, Daily Digest, and Rebuttal workflows built in.
• PaperClaw - OpenClaw skill for generating topic-specific expert agents for paper search, review, and critique workflows.
• Prismer - End-to-end research platform with PDF reading, Jupyter, LaTeX, code execution, and citation verification.
• Research Claw - Self-hosted academic assistant by nanoAgentTeam for paper management, literature search, deadline tracking, and LaTeX/Overleaf sync.
• ResearchClaw - Local-first Research OS by ymx10086 with claims/evidence graph, experiment tracking, paper management, skills, and multi-channel access.
• sciClaw - Paired-scientist agent (Go/PicoClaw runtime) with Telegram/Discord interface, PubMed integration, reproducible experiment logging, skill library, and multi-provider LLM support.
• Scientify - Continuous-metabolism research system that tracks papers, evolves hypotheses, runs validation experiments, and proactively pushes updates.

Skill Libraries & Extensions

Reusable OpenClaw skill ecosystems for domain expertise, automation, and tool augmentation.

• LabClaw - 240 OpenClaw skills for biology, pharmacology, medicine, literature, and visualization.
• OpenClaw-Medical-Skills - 869 medical/biomedical skills spanning clinical, genomics, and drug discovery domains.
• SkillNet - Skill creation, evaluation, connection, and discovery infrastructure that searches 300k+ community skills.

Commercial Platforms

Full Research Automation

Commercial systems focused on autonomous end-to-end scientific research execution and acceleration.

• Analemma - Fully autonomous research system for end-to-end scientific research automation.
• DeepScientist - AI platform for accelerating scientific research and discovery.
• Edison Scientific - Autonomous AI scientist for end-to-end research automation.
• FutureHouse - AI platform building autonomous systems to accelerate scientific discovery.

Literature Discovery & Search

Commercial tools for discovering, searching, and synthesizing scientific literature at scale.

• AI Researcher - AI-powered research assistant for literature review and research synthesis.
• AiraXiv - AI research platform for automated paper discovery and analysis.
• Consensus - AI search engine that finds and summarizes scientific research papers.
• Elicit - AI research assistant that automates literature review workflows.

Paper Review & Management

Commercial platforms for paper understanding, review workflows, and research knowledge management.

• IBM Watson Discovery - Enterprise AI platform for intelligent document understanding and search.
• paper2skills - AI-powered platform that converts research papers into actionable skills.
• PaperReview - AI-powered platform for automated paper review and feedback.
• SciSpace - AI copilot for research paper reading, writing, and understanding.

Self-driving Labs

Automated laboratory platforms and initiatives that integrate robotics, AI, and closed-loop experimentation.

• Acceleration Consortium - University of Toronto-led initiative advancing self-driving labs for materials acceleration and autonomous experimentation.
• Emerald Cloud Lab - Cloud-based robotic laboratory platform for programmable and remotely executed experiments.
• IBM RXN for Chemistry - AI platform for chemistry synthesis planning and autonomous lab workflow integration.
• Strateos - Remote robotic lab platform for automated experiment execution and high-throughput biology workflows.

Contributing

Contributions are welcome! Please feel free to submit a pull request to add more AutoResearch tools to this awesome list.