The dynamic landscape of peptide function prediction

This curated list collects peer-reviewed machine learning models dedicated to predicting specific properties of peptides. For an interactive and browse-able list, please visit: https://biogenies.info/peptide-prediction-list/.

• Antiangiogenic peptides
• Antibacterial peptides (ABP)
• Antibiofilm peptides
• Anticancer peptides (ACP)
• Antifungal peptides (AFP)
• Antihypertensive peptides
• Antiinflammatory peptides (AIP)
• Antimicrobial peptides (AMP)
• Antiparasitic peptides (APP)
• Antiviral peptides (AVP)
• Blood-brain barrier peptides (BBP)
• Cell-penetrating peptides (CPP)
• Chemotactic peptides
• Neuropeptides peptides
• Quorum sensing peptides
• Surface-binding peptides
• Toxic peptides (TP)

Antiangiogenic peptides

1. AntAngioCOOL (2019): publication; model repository.
2. AntiAngioPred (2015): publication; web server.
3. Pep-CNN (2022): publication; training repository; model repository.
4. PEPred-Suite (2019): publication; web server.
5. PPTPP (2020): publication; training repository; model repository.
6. TargetAntiAngio (2019): publication; training repository; model repository; web server.
7. TPpred-ATMV (2022): publication; model repository.
8. Zhang et al. (2018): publication.

Antibacterial peptides (ABP)

1. ClassAMP (2012): publication; web server.
2. Deep-ABPpred (2021): publication; web server.
3. iAMP-CA2L (2021): publication; training repository; model repository; web server.
4. iAMPpred (2017): publication; web server.
5. MAMPs-Pred (2019): publication.
6. Pep-CNN (2022): publication; training repository; model repository.
7. PEPred-Suite (2019): publication; web server.
8. PPTPP (2020): publication; training repository; model repository.
9. PreTP-EL (2021): publication; web server.
10. PreTP-Stack (2022): publication; web server.
11. StaBle-ABPpred (2021): publication; web server.
12. TP-MV (2022): publication.
13. TPpred-ATMV (2022): publication; model repository.
14. Zhang et al. (2021): publication; training repository; model repository.

Antibiofilm peptides

1. dPABBs (2016): publication; web server.
2. iAMP-CA2L (2021): publication; training repository; model repository; web server.

Anticancer peptides (ACP)

1. ACHP (2021): publication; web server.
2. ACP-2DCNN (2022): publication.
3. ACP-DA (2021): publication; model repository.
4. ACP-DL (2019): publication; training repository; model repository.
5. ACP-MHCNN (2021): publication; training repository; model repository; web server.
6. ACPNet (2022): publication; training repository; model repository.
7. ACPP (2014): publication; web server.
8. ACPred (2019): publication; web server.
9. ACPred-FL (2018): publication; web server.
10. ACPred-Fuse (2019): publication; web server.
11. AntiCP (2013): publication; web server.
12. AntiCP 2.0 (2020): publication; model repository; web server.
13. cACP-2LFS (2020): publication; training repository; model repository.
14. CancerGram (2020): publication; training repository; model repository; web server.
15. DeepACP (2020): publication; training repository; model repository.
16. DLACP (2020): publication.
17. DLFF-ACP (2021): publication; training repository; model repository.
18. DRACP (2020): publication.
19. Hajisharifi et al. (2014): publication.
20. iACP (2016): publication; web server.
21. iACP-DRLF (2021): publication; model repository.
22. iACP-FSCM (2021): publication; training repository; model repository; web server.
23. iACP-GAEnsC (2017): publication.
24. iAMP-CA2L (2021): publication; training repository; model repository; web server.
25. Khan et al. (2017): publication.
26. Li & Wang (2016): publication.
27. Li et al. (2020): publication.
28. mACPpred (2019): publication; web server.
29. MAMPs-Pred (2019): publication.
30. ME-ACP (2022): publication; training repository; model repository.
31. MLACP (2017): publication; web server.
32. MLBP (2021): publication; training repository; model repository; web server.
33. MPMABP (2022): publication; training repository; model repository.
34. Pep-CNN (2022): publication; training repository; model repository.
35. PPTPP (2020): publication; training repository; model repository.
36. PreTP-EL (2021): publication; web server.
37. PreTP-Stack (2022): publication; web server.
38. SAP (2018): publication.
39. StackACPred (2022): publication; training repository; model repository.
40. TargetACP (2018): publication.
41. TPpred-ATMV (2022): publication; model repository.
42. xDeep-AcPEP (2021): publication; training repository; model repository; web server.

Antifungal peptides (AFP)

1. Antifp (2018): publication; web server.
2. ClassAMP (2012): publication; web server.
3. Deep-AFPpred (2021): publication; web server.
4. Deep-AntiFP (2021): publication; model repository.
5. iAFPs-EnC-GA (2022): publication; model repository.
6. iAMP-CA2L (2021): publication; training repository; model repository; web server.
7. iAMPpred (2017): publication; web server.
8. Mousavizadegan & Mohabatkar (2018): publication.
9. PEPred-Suite (2019): publication; web server.
10. TCN-AFPpred (2022): publication; web server.

Antihypertensive peptides

1. ACHP (2021): publication; web server.
2. mAHTPred (2018): publication; web server.
3. MLBP (2021): publication; training repository; model repository; web server.
4. MPMABP (2022): publication; training repository; model repository.
5. PAAP (2018): publication; training repository; model repository; web server.
6. Rauf et al. (2021): publication.
7. Wang et al. (2021): publication.

Antiinflammatory peptides (AIP)

1. AIEpred (2021): publication; training repository; model repository.
2. AIPpred (2018): publication; web server.
3. AntiFlamPred (2021): publication.
4. AntiInflam (2017): publication; web server.
5. MLBP (2021): publication; training repository; model repository; web server.
6. MPMABP (2022): publication; training repository; model repository.
7. Pep-CNN (2022): publication; training repository; model repository.
8. PEPred-Suite (2019): publication; web server.
9. PPTPP (2020): publication; training repository; model repository.
10. PreAIP (2019): publication; web server.
11. PreTP-EL (2021): publication; web server.
12. PreTP-Stack (2022): publication; web server.
13. TPpred-ATMV (2022): publication; model repository.

Antimicrobial peptides (AMP)

1. ACEP (2020): publication; training repository; model repository.
2. AI4AMP (2021): publication; training repository; model repository; web server.
3. AMAP (2019): publication; web server.
4. AMP0 (2022): publication; web server.
5. AMPDiscover (2021): publication; web server.
6. AmPEP (2018): publication; model repository; web server.
7. amPEPpy 1.0 (2020): publication; training repository; model repository.
8. AmpGram (2020): publication; training repository; model repository; web server.
9. Ampir (2020): publication; training repository; model repository; web server.
10. AMPlify (2022): publication; training repository; model repository.
11. AMPpred-EL (2022): publication.
12. AMPScanner V2 (2018): publication; web server.
13. ANFIS (2012): publication.
14. AniAMPpred (2021): publication; web server.
15. APIN (2019): publication; training repository; model repository.
16. CAMP (2009): publication.
17. CAMPR3 (2015): publication; web server.
18. ClassAMP (2012): publication; web server.
19. Co-AMPpred (2021): publication; training repository; model repository.
20. CS-AMPPred (2012): publication; model repository.
21. DBAASP (2014): publication; web server.
22. Deep-AmPEP30 (2020): publication; training repository; model repository; web server.
23. Ensemble-AMPPred (2021): publication; training repository; model repository.
24. Healy et al. (2021): publication; model repository.
25. iAMP-2L (2013): publication; web server.
26. iAMP-CA2L (2021): publication; training repository; model repository; web server.
27. IAMPE (2020): publication; web server.
28. Ma et al. (2022): publication; model repository.
29. Maccari et al. (2013): publication.
30. Macrel (2020): publication; training repository; model repository; web server.
31. MAMPs-Pred (2019): publication.
32. MLAMP (2016): publication; web server.
33. MLBP (2021): publication; training repository; model repository; web server.
34. MPMABP (2022): publication; training repository; model repository.
35. Ng et al. (2015): publication.
36. PepVAE3 (2021): publication.
37. sAMP-PFPDeep (2021): publication; model repository.
38. Wang et al. (2011): publication; web server.
39. Wani et al. (2021): publication; model repository.
40. Zhang et al. (2021): publication; training repository; model repository.

Antiparasitic peptides (APP)

1. i2APP (2022): publication; training repository; model repository.
2. MAMPs-Pred (2019): publication.
3. PredAPP (2021): publication; training repository; model repository; web server.

Antiviral peptides (AVP)

1. AntiVPP 1.0 (2019): publication; model repository.
2. AVP‐IC50Pred (2015): publication; web server.
3. AVPIden (2021): publication; model repository; web server.
4. AVPpred (2012): publication; web server.
5. Bakare et al. (2021): publication.
6. ClassAMP (2012): publication; web server.
7. DeepAVP (2020): publication; web server.
8. ENNAVIA (2021): publication; web server.
9. FIRM-AVP (2020): publication; training repository; model repository; web server.
10. iACVP (2022): publication; training repository; model repository; web server.
11. iAMPpred (2017): publication; web server.
12. MAMPs-Pred (2019): publication.
13. Meta-iAVP (2019): publication; web server.
14. Pep-CNN (2022): publication; training repository; model repository.
15. PEPred-Suite (2019): publication; web server.
16. PPTPP (2020): publication; training repository; model repository.
17. PreAntiCoV (2021): publication; training repository; model repository.
18. PreTP-EL (2021): publication; web server.
19. PreTP-Stack (2022): publication; web server.
20. TPpred-ATMV (2022): publication; model repository.

Blood-brain barrier peptides (BBP)

1. B3Pred (2021): publication; web server.
2. BBPpred (2021): publication; web server.
3. Zou (2021): publication.

Cell-penetrating peptides (CPP)

1. BChemRF-CPPred (2021): publication; web server.
2. CPPred-RF (2017): publication; web server.
3. ITP-Pred (2020): publication.
4. KELM-CPPpred (2018): publication; web server.
5. Liu et al. (2022): publication.
6. MLCPP (2018): publication; web server.
7. MLCPP 2.0 (2022): publication; web server.
8. Pep-CNN (2022): publication; training repository; model repository.
9. PEPred-Suite (2019): publication; web server.
10. PPTPP (2020): publication; training repository; model repository.
11. PreTP-EL (2021): publication; web server.
12. PreTP-Stack (2022): publication; web server.
13. SkipCPP-Pred (2017): publication; web server.
14. TargetCPP (2020): publication; training repository; model repository.
15. TP-MV (2022): publication.
16. TPpred-ATMV (2022): publication; model repository.
17. GraphCPP (2024): publication; model repository; data repository.

Chemotactic peptides

1. iAMP-CA2L (2021): publication; training repository; model repository; web server.

Neuropeptides peptides

1. NeuroPIpred (2019): publication; web server.
2. NeuroPP (2018): publication; web server.
3. NeuroPpred-Fuse (2021): publication; model repository.
4. NeuroPred-FRL (2021): publication; web server.
5. PredNeuroP (2020): publication; training repository; model repository.

Quorum sensing peptides

1. EnsembleQS (2022): publication; training repository; model repository.
2. iQSP (2019): publication; web server.
3. ITP-Pred (2020): publication.
4. Pep-CNN (2022): publication; training repository; model repository.
5. PEPred-Suite (2019): publication; web server.
6. PPTPP (2020): publication; training repository; model repository.
7. PreTP-EL (2021): publication; web server.
8. PreTP-Stack (2022): publication; web server.
9. QSPpred (2015): publication; web server.
10. QSPred-FL (2018): publication; web server.
11. TP-MV (2022): publication.
12. TPpred-ATMV (2022): publication; model repository.

Surface-binding peptides

1. Pep-CNN (2022): publication; training repository; model repository.
2. PEPred-Suite (2019): publication; web server.
3. PPTPP (2020): publication; training repository; model repository.
4. PreTP-EL (2021): publication; web server.
5. PreTP-Stack (2022): publication; web server.
6. TPpred-ATMV (2022): publication; model repository.

Toxic peptides (TP)

1. ATSE (2021): publication; web server.
2. ToxIBTL (2022): publication; model repository; web server.
3. ToxinPred (2014): publication; web server.

About and citation

This website accompanies our publication: The dynamic landscape of peptide function prediction.

Citation: Oriol Bárcenas, Carlos Pintado-Grima, Katarzyna Sidorczuk, Felix Teufel, Henrik Nielsen, Salvador Ventura and Michał Burdukiewicz, The dynamic landscape of peptide function prediction, Computational and Structural Biotechnology Journal, 10.1016/j.csbj.2022.11.043.