Skip to content
View SamantGayatri2002's full-sized avatar
🎯
Focusing
🎯
Focusing

Block or report SamantGayatri2002

Block user

Prevent this user from interacting with your repositories and sending you notifications. Learn more about blocking users.

You must be logged in to block users.

Maximum 250 characters. Please don't include any personal information such as legal names or email addresses. Markdown supported. This note will be visible to only you.
Report abuse

Contact GitHub support about this user’s behavior. Learn more about reporting abuse.

Report abuse
SamantGayatri2002/README.md

Hi there πŸ‘‹

I'm Gayatri Samant

Gayatri Samant

πŸŽ“ Aspiring Bioinformatics Researcher | Genomics & Public Health
πŸ”¬ Passionate about uncovering insights from biological data using NGS analysis, computational biology, and machine learning.


πŸš€ About Me

  • 🧬 Completed M.Sc. in Bioinformatics with strong academic performance (CGPA: 8.93).
  • πŸ”Ž Experienced in analyzing NGS datasets (WES, RNA-seq, microarray, metagenomics) through reproducible pipelines.
  • πŸ’» Skilled in Python, R, Bash, Linux/Unix, Docker for bioinformatics and data science applications.
  • 🀝 Open to research and industry collaborations in computational genomics, transcriptomics, and clinical bioinformatics.
  • 🌟 Keen to apply bioinformatics for translational genomics, precision medicine, and public health.

πŸ› οΈ Skills

Programming & Scripting: Python, R, Bash
NGS & Genomics: RNA-seq, WES, WGS, DEG analysis, variant calling, metagenomics
Pipelines & Tools: HISAT2, BWA, samtools, GATK, bcftools, DESeq2, limma, Kraken2, Bracken, QIIME2, Docker
Databases: NCBI, Ensembl, UniProt, GeneCards, STRING, PDBsum
Machine Learning: kNN, SVM, Random Forest
Visualization: PCA, Heatmaps, Volcano plots, Pathway Enrichment


πŸ“‚ Projects & Experience

  • 🧬 Variant Calling in Ewing Sarcoma (WES) – Built a reproducible clinical genomics pipeline (BWA, GATK, Ensembl VEP, SnpEff).
  • πŸ”Ž RNA-Seq Hypoxia Study – Analyzed 20 runs from prostate cancer cell lines, performed DEG analysis (DESeq2), PCA, heatmaps, volcano plots, and pathway enrichment.
  • πŸ€– Cervical Cancer DEG with ML – Applied classification models (SVM, Random Forest, kNN) to microarray-based gene expression data.
  • 🦠 Metagenomics Pipelines – Performed taxonomic classification and abundance profiling using Kraken2, Bracken, and QIIME2.
  • πŸ§ͺ In-Silico CRISPR-Cas13 Dengue Detection – Designed guide RNAs, validated RNA structures, and checked off-targets for virus detection feasibility.

🌐 Connect with Me

πŸ“§ [email protected]
πŸ’Ό LinkedIn
πŸ’» GitHub Portfolio


✨ "Turning biological data into meaningful insights through bioinformatics and computational genomics."

Pinned Loading

  1. Complete-ChIP-Seq-Pipeline-for-USF2-Transcription-Factor-in-HepG2-Cells Complete-ChIP-Seq-Pipeline-for-USF2-Transcription-Factor-in-HepG2-Cells Public

    This project documents the Detailed Analysis Transcription Factor Binding sites in a ChIP Seq data.

    HTML

  2. ML_Based_Analysis_of_Gut_Microbiome_in_Colorectal_Cancer_Dataset ML_Based_Analysis_of_Gut_Microbiome_in_Colorectal_Cancer_Dataset Public

    Shotgun metagenomics based microbiome analysis of colorectal cancer using Machine Learning classifiers to build predictive diagnostic models and explore gut microbiome signatures.

    Jupyter Notebook

  3. DNA-Methylation-Analysis-of-GSE42861-Illumina-450K-Array- DNA-Methylation-Analysis-of-GSE42861-Illumina-450K-Array- Public

    A personal learning project documenting my first complete methylation workflow using R & Bioconductor.

  4. Bulk-RNA-Seq-Data-Analysis Bulk-RNA-Seq-Data-Analysis Public

    This project demonstrates step-by-step analysis of Bulk RNA-Seq data, starting from raw SRA files to obtaining differentially expressed genes (DEGs).

    HTML

  5. Cervical-cancer-DEG-analysis-using-ML Cervical-cancer-DEG-analysis-using-ML Public

    Final project for NyberMan 15 days internship held during 19th july to 3rd Aug 2025.

    R

  6. Clinical-Genomics-Project Clinical-Genomics-Project Public template

    This was the dissertation project on Variant calling and predictive annotation of "Ewing sarcoma" done at Mediomix diagnosis and Bioresearch Pvt ltd, bengaluru.

    HTML