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Here, I have two questions.
Firstly, i want to input a pdb file which composed of only one protein chain. I need to fix the positions from 1-150 and design 151-160, for example. Besides, i hope to design a homooligomer, like dimer, using the position 151-160. How can i do it?
Secondly, if i design the postion from 151-160 to a more long sequences, can ProteinMPNN do it?
In all, the scaffold i design is to small to help me solve the structure through cryoEM, so i hope to make it more biger no matter through dimer-design or add more ridgy domain.
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