variants_db_lamindb_usecase

[biocoder1001]

The following draft includes:

1. VCF Collection Management
   Aggregating multiple summary-level VCF files into a unified collection

2. Functional Annotation Pipeline
   GSEApy integration for gene set enrichment analysis
   KEGG pathway annotation for biological context

3. RNA Editing Context
   Cross-referencing mutation positions with known RNA editing sites
   Helps distinguish true mutations from RNA editing events

4. Organizational Structure
   Stratifying variants by mutation type (snp, tandem repeats region mutations)
   Creating sub-collections for easier querying and analysis