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ARES: aproximated RNA evolution simulator

Installation

Install dependencies:

ViennaRNA
conda install viennarna

Infernal
conda install -c bioconda infernal

Download code and prepare Rfam database

wget https://github.com/sahakyanhk/ares/archive/refs/heads/main.zip -O ares.zip; unzip ares.zip

bash ares/src/make_rfam_db.sh

python src/ares.py

Usage

python src/ares.py --nobackup -iseq random --random_seq_len 90  -o test/run1 -ps 100 -ng 500 -ed rna -em single_chain -b 1

python src/arestools.py -l test/run1/progress.log -o test/run1

or submit a sbatch job with SLURM:

bash run_ares.sbatch test/run

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