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tomi-jacobs/README.md

Hi, I'm Tomi

A 3rd year PhD Candidate studying the dynamics of computation and genetics, building bioinformatics pipelines by utilizing shell scripting, programming languages, and models to decode large-scale phylotranscriptomics data.

Research Interests

Bioinformatics: Methods development & Phylogenomics

Research Highlights


Pythia Difficulty Score
Ph.D. — UIC

Conflict Analysis
Ph.D. — UIC

Differential Gene Expression
Fellow — Cornell

Sample Correlation Heatmap
Fellow — Cornell

Featured Projects

Pythia Difficulty Score Analysis

Applied the Pythia tool to evaluate per-dataset difficulty scores across phylogenetic clusters. The distribution of predicted difficulty scores was used to classify datasets as easy, intermediate, or difficult — informing downstream phylogenetic inference strategies.

Conflict Analysis across datasets

Phylogenetic conflict analysis examining the proportion of concordant, uninformative, and conflicting sites across the dataset. Each category reflects the degree of agreement between gene trees and the species tree.

WGCNA for Sugar Maple Transcriptomics

Carried out bioinformatics research using Weighted Gene Correlation Network Analysis (WGCNA) to identify key genes regulating drought resistance in Acer saccharum (Sugar Maple). Pipeline included DESeq2 differential expression analysis, variance stabilizing transformation, and co-expression network construction.

🔗 View Repository

Skills & Tools

Python R Bash Linux HPC

"Advancing science, one code at a time."

Pinned Loading

  1. pythia_batch_predictor pythia_batch_predictor Public

    Python 1

  2. WGCNA_MapleOmics WGCNA_MapleOmics Public

    I worked on this during my time at Cornell as a Masters student, when I studied drought resistance in Sugar Maple plants.

    R 1